Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDFMNFFILGADLPTLGGVKGWASDVVIQFITIVV--MFIAAKNLMKLKM---------------GGIIFVCCIGSAVTWVIK---HWSEFSGWINALMEKL 2LZ0 Chain:A ((1-100)) GSHEGEPVVGMDKSLFAGNTVIREITVQPNIGLLYDGMFSGCTALEKLILTGEDPSAYSAGDGLRDGADFLICVPEEALDRYRRDYFWQTYAAWIQPMEQ--

General information: TITO was launched using: RESULT: Template: 2LZ0.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 255 -62707 -245.91 -783.84 target 2D structure prediction score : 0.30 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : -245.91 2D Compatibility (Sec. Struct. Predict.) : 0.30 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.092

(partial model without unconserved sides chains): PDB file : Tito_2LZ0.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2LZ0-query.scw PDB file : Tito_Scwrl_2LZ0.pdb: