Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKFAVIVLPGSNCDIDM----YHAVKDELGHEVEYVWHEETSLDGFDGVLIPGGFSYGDYLRCG---AIARFANIMPAVKQAAAEGKP---VLGVCNGFQILQELG-LLPGA-----MRRNKDLKFICRPVELIVQNDETLFTASYEKGESITIPVAHGEGNFYC-DDETLATLKENNQIAF-----------TYGSNINGSVSDIAGVVNEKGNVLGMMPHPERAVDELLGSADGLKLFQSIVKNWRETHVTTA 3UGJ Chain:A ((1049-1280)) -KVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLLGGRIGLGNFHALVACGGFSYGDVLGAGEGWAKSILFNHRVRDEFETFFHRPQTLALGVCNGCQMMSNLRELIPGSELWPRFVRNHSDRFEARFSLVEVTQSPSLLLQGM-VGSQMPIAVSHGEGRVEVRDDAHLAALESKGLVALRYVDNFGKVTETYPANPNGSPNGITAVTTENGRVTIMMPHPER-------------VFRTVANSW--------

General information: TITO was launched using: RESULT: Template: 3UGJ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1083 -95718 -88.38 -469.21 target 2D structure prediction score : 0.55 Monomeric hydrophicity matching model chain A : 0.73 3D Compatibility (PKB) : -88.38 2D Compatibility (Sec. Struct. Predict.) : 0.55 1D Compatibility (Hydrophobicity) : 0.73 QMean score : 0.320

(partial model without unconserved sides chains): PDB file : Tito_3UGJ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3UGJ-query.scw PDB file : Tito_Scwrl_3UGJ.pdb: