Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKRVLFSVIVFTAV---GFTFCQSKAHALTFTVLPITQKTDQWSVKVSEAKNVKEFTRPHKGEYQVYSL-EVKNIGEKAATVDVQLYRND--PNSITRFSLFGCPDENCVKPKEDS-KMLAESLNDGSPLKFNHFMLADKASELEVVIIWTQKGQEGRN------LKQTFKFTEDGVN-------- 4MGX Chain:A ((1-185)) QKVRAWGPGLETGQVGKSADFVVEAIGTLGFSIEGPSQAKIECDDKGDGSCDVRYWPTE-PGEYAVHVICDDEDIRDSPFIAHILPAPPDCFPDKVKAFG-PGLEPTGCIVDKPAEFTIDARAAGKGD---LKLYAQDADGCPIDIKVIPNGDGTFRCSYVPTKPIKHTIIISWGGVNVPKSPFRV

General information: TITO was launched using: RESULT: Template: 4MGX.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 699 9654 13.81 60.33 target 2D structure prediction score : 0.53 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : 13.81 2D Compatibility (Sec. Struct. Predict.) : 0.53 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.237

(partial model without unconserved sides chains): PDB file : Tito_4MGX.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4MGX-query.scw PDB file : Tito_Scwrl_4MGX.pdb: