Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ---MNFLLDLFTNWTFDKVLDYTLAAVIWSVFKSRSKQNKY---PGYFEKIRRYRNLHPLLRSLSMRVLLSITIHPYMFS 4MYY Chain:A ((2-85)) SALEAKLLDEIKQSS-NQELESSIDQILESIINGGSMLNKFTKKEQILSEKQQIKQLSPLQRAALALKKLETKLNNTLHE

General information: TITO was launched using: RESULT: Template: 4MYY.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 116 -5314 -45.81 -72.79 target 2D structure prediction score : 0.74 Monomeric hydrophicity matching model chain A : 0.67 3D Compatibility (PKB) : -45.81 2D Compatibility (Sec. Struct. Predict.) : 0.74 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.411

(partial model without unconserved sides chains): PDB file : Tito_4MYY.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4MYY-query.scw PDB file : Tito_Scwrl_4MYY.pdb: