Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDFEKMKQWMEFAQQMYGGDFWKQVFDEDQKTPFMTNGQSPFPFAQQDQRGKGDASFPSMDIVDTVAEVQFLIYLPGYRKQDVHILSYGDYLVVKG----QRFSYFNEQDFRQKEGKYGSFEKKIPLSDHLHG-KMNAIFKDGILYITIQKDEGQAKTIVIDD 3W1Z Chain:A ((37-132)) ---------------------------------------------------------PSIDVHEGKDTVSVDVELPGVKKEDVQVHYDSGKLTISGEVVNERKNESTEGNQRWSERRFGSFSRTITIPAKIDADRIEANFSNGLLTVTLPKVE----------

General information: TITO was launched using: RESULT: Template: 3W1Z.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 296 -12968 -43.81 -142.50 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain A : 0.67 3D Compatibility (PKB) : -43.81 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.588

(partial model without unconserved sides chains): PDB file : Tito_3W1Z.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3W1Z-query.scw PDB file : Tito_Scwrl_3W1Z.pdb: