Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MESKIEILSTINVEHSDDLYKIVDTLNRTLKRDNLMFGLALDEENKNQAVFTIYRT-------------------------- 1XN7 Chain:A ((1-78)) MASLIQVRDLLALRGRMEAAQISQTLNTP----QPMINAMLQQLESMGKAVRIQEEPDGCLSGSCKSCPEGKACLREWWALR

General information: TITO was launched using: RESULT: Template: 1XN7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 154 -20829 -135.25 -400.55 target 2D structure prediction score : 0.46 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : -135.25 2D Compatibility (Sec. Struct. Predict.) : 0.46 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.337

(partial model without unconserved sides chains): PDB file : Tito_1XN7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1XN7-query.scw PDB file : Tito_Scwrl_1XN7.pdb: