Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEYALHEVLEVQEMTAFKTLCLTKSKTMKALVSDPKLKEIMQQDVDITTRQLQEFASILSNAKQE 1PGY Chain:A ((1-47)) ---ALVDEVKDMEIARLMSLGL----------SIEEATEFYENDVTY-----ERYLEILKSKQKE

General information: TITO was launched using: RESULT: Template: 1PGY.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 85 -12133 -142.74 -258.15 target 2D structure prediction score : 0.81 Monomeric hydrophicity matching model chain A : 0.69 3D Compatibility (PKB) : -142.74 2D Compatibility (Sec. Struct. Predict.) : 0.81 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.752

(partial model without unconserved sides chains): PDB file : Tito_1PGY.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1PGY-query.scw PDB file : Tito_Scwrl_1PGY.pdb: