Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEELLTIAFRTVVLYFVILVIFRFMGKREIGELSILDLVVFIMMAEIAVLAIENVDDHLFHTILPMLVLMIIQVTLAYFSLKNRKVRQLLDGKPTIIIKYGKIDEEAMKSQRYNFDDLMVQLRENSIDRVADVSFAILEPSGKLTIVKKE--NSGEHRQLEMP---------LIIDGFIQTENLSRISKDRKWLLESLQKHGYTNPSDISFCSFTDGEIYIDEKDGHRT 3C6F Chain:A ((16-136)) ---------------------------------------------------------------------------------------------PNIVIRKGELQYKVMKKNKIDINQLQSMLRQAGSFSIQEVEYAIMETNGMVSVLPKSDFDKPTNKDMQIPSKSVSLPITLIIDGEIVRDNLKEAGVDEQWLKQEMKKKNIDKTEDVLFAEW---------------

General information: TITO was launched using: RESULT: Template: 3C6F.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 286 -26797 -93.70 -243.61 target 2D structure prediction score : 0.74 Monomeric hydrophicity matching model chain A : 0.59 3D Compatibility (PKB) : -93.70 2D Compatibility (Sec. Struct. Predict.) : 0.74 1D Compatibility (Hydrophobicity) : 0.59 QMean score : 0.674

(partial model without unconserved sides chains): PDB file : Tito_3C6F.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3C6F-query.scw PDB file : Tito_Scwrl_3C6F.pdb: