Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKEKLRLYHTNDLHSHFEN---------------WPKIVDYIEQKRKEHQSDGEETLVFDIGDHLDRFQFVTEATFGKANVDLLNRLHIDGAAIGNNEGITLPHEELAALYDHAEFPVIVSNLFD-KNGNRPSWAVPYHIKSLKNGMSIAFLGVTVPYYPVY-----DKLGWTVTDALESIKETILEVKGQADIIVLLSHLGILDD-------------QAVAEAVPEIDVILESHTHHLLEDGQVVNGVLLASAEKYGHYVGCVEITVDSVQRSINSKTASVQNM--AEWTGESAETKAFLNEKEREAEEKLSDAVAELAQDAEVKWFEESELPLLLAYALKEWCE--TDISMVNSGVILGPLKAGPVTKLDLHRICPHPINPVAVRLTGEELKETIVHAASEQMEQLRIKGLGFRGEVMGKMVYA-GVEVETKRLDDGITHVTRITLNGEDIEKHKQYSVAVLDMFTLGKL-FPLIRDAAEKEYFMPEFLRDLLAWKLAQ 3IVE Chain:A ((4-483)) -AKDVTIIYTNDLHAHVEPYKVPWIADGKRDIGGWANITTLVKQEKAKN----KATWFFDAGDYFTGPY-ISSLTKGKAIIDIMNTMPFDAVTIGNHEFDH-GWDNTLLQLSQAKFPIVQGNIFYQNSSKS-FWDKPYTIIE-KDGVKIGVIGLHGVFAFNDTVSAATRVGIEARDEIKWLQRYIDELKGKVDLTVALIHEGVPARQSSMDVRRALDKDIQTASQVKGLDILITGHAHVGTPEPIKVGNTLILSTDSGGIDVGKLVLDYKEKPHNFTVKNFELKTIYADEWK-PDQQTKQVIDGWNKKLDEVVQQTVAQSPVELKRAYGESASLGNLAADALLAAAGKNTQLALTNSGGIRNEIPAGAITMGGVISTFPFPNELVTMELTGKQLRSLMEHGASLS--------NGVL-------QVSKGLEMKYDSSKPVGQRVITLTLNGKPIEDATVYHIATQSFLADGGDGFTAFTEGKARNITGGYYVYHAVVDYFKA

General information: TITO was launched using: RESULT: Template: 3IVE.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2666 76518 28.70 175.10 target 2D structure prediction score : 0.54 Monomeric hydrophicity matching model chain A : 0.71 3D Compatibility (PKB) : 28.70 2D Compatibility (Sec. Struct. Predict.) : 0.54 1D Compatibility (Hydrophobicity) : 0.71 QMean score : 0.497

(partial model without unconserved sides chains): PDB file : Tito_3IVE.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3IVE-query.scw PDB file : Tito_Scwrl_3IVE.pdb: