Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNMQKLRIELGEETNDELYDLLLLADPSKDIVDEYLERGECYTAWAGDELAGVYVLLKTRPQTVEIVNIAVKESLQKKGFGKQLVLDAIEKAKKLGADTIEIGTGNSSIHQLSLYQKCGFRIQAIDHDFFLRHYDEDIFENGIQCRDMVRLYLDL 1YVK Chain:C ((5-155)) ----KLRIELGEETNDELYDLLLLADPSKDIVDEYLERGECYTAWAGDELAGVYVLLKTRPQTVEIVNIAVKESLQKKGFGKQLVLDAIEKAKKLGADTIEIGTGNSSIHQLSLYQKCGFRIQAIDHDFFLRHYDEDIFENGIQCRDMVRLYLDL

General information: TITO was launched using: RESULT: Template: 1YVK.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 697 -88867 -127.50 -588.52 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain C : 0.99 3D Compatibility (PKB) : -127.50 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.99 QMean score : 0.535

(partial model without unconserved sides chains): PDB file : Tito_1YVK.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1YVK-query.scw PDB file : Tito_Scwrl_1YVK.pdb: