Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLAAEDPEKEISLYINSPGGSITAGMAIYDTMQFIKPKVSTICIGMAASMGAFLLAAGEKGKRYALPNSEVMIHQPLGGAQGQATEIEIAAKRILLLRDKLNKVLAERTGQPLEVIERDTDRDNFKSAEEALEYGLIDKILTHTEDKK 3TT7 Chain:F ((4-191)) ---IPTVI--------AYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLAAEDPEKEISLYINSPGGSITAGMAIYDTMQFIKPKVSTICIGMAASMGAFLLAAGEKGKRYALPNSEVMIHQPLGGAQGQATEIEIAAKRILLLRDKLNKVLAERTGQPLEVIERDTDRDNFKSAEEALEYGLIDKILT------

General information: TITO was launched using: RESULT: Template: 3TT7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain F - contact count / total energy / energy per contact / energy per residue : 820 -117530 -143.33 -652.94 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain F : 0.98 3D Compatibility (PKB) : -143.33 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.98 QMean score : 0.636

(partial model without unconserved sides chains): PDB file : Tito_3TT7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3TT7-query.scw PDB file : Tito_Scwrl_3TT7.pdb: