Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MGESTSLKEILSTLTKRILLIMIVTAAATAAGGLISFFALTPIYENSTQILVNQSKNERKEVQFNDVQTNLQLINTYNVIIKSPAILDEVIKEMGLSMTSQELNDKITVSSEQDSQVVNISVRDENAETAAHIANTIASVFQDKITSIMNVDNVSILSKAEVSEHPSPVSPKPLLNIAIAFAAGLAGSI---------GLAFLLEHLDNTIKSEEQLESL---LDIPVLGTVSTIANEQKTAKTLQGFQSEKTGSGHFGA 1Y5R Chain:A ((104-204)) -----------------------------------------------------------------------------------------------------------------------------------HITQTSLSLFHDDIHSVRRVMEVNFLSYVVMSTAALPMLKQS--NGSIAVISSLAGKMTQPMIAPYSASKFALDGFFSTIRTELYITKVNVSITLCVLGLIDT--------------------------

General information: TITO was launched using: RESULT: Template: 1Y5R.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 255 -16204 -63.54 -182.06 target 2D structure prediction score : 0.30 Monomeric hydrophicity matching model chain A : 0.60 3D Compatibility (PKB) : -63.54 2D Compatibility (Sec. Struct. Predict.) : 0.30 1D Compatibility (Hydrophobicity) : 0.60 QMean score : 0.228

(partial model without unconserved sides chains): PDB file : Tito_1Y5R.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1Y5R-query.scw PDB file : Tito_Scwrl_1Y5R.pdb: