Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTAHDQELRRRAYEEVEKKEPIANSDPHRQHFHIMPPVGLLNDPNGVIYWKGSYHVFFQWQPFQTGHG-AKFWGHYTTQDVVNWKREEIALAPSDWFDKNGCYSGSAVTK-DDRLYLFYTGNVRDQD----GNRETYQCLAVSDD--GLSFEKKG-VVARLPEGYTAHFRDPKVWEHEGTWYMVIGAQTENLKGQAVLFASDNLTEWRFLGPITGAGFNGLDDFGYMWECPDLFSLQ-----GSDVLIVSPQGLEADGFRYQNVYQSGYFVGRLDYNKPELKHG-EFTELDQGFDFYAPQTLEDDQGRRILFAWMAVPDQDEGSHPTIDCHWIHCMTLPRQLTLS-GQKLIQQPLPELKAMRRNEKKI-HINMHGSSGALPV-EKPERTEILLE-DIH--TESGFSISIRGT-----ATFSFHKDEGIVTLERKSFDG-K--RT--EARHCRI-KDLHTVHMFLDASSVEIFINNGEEVLSARYFPFPGNHEVTASATGK--SEMNVGIWTLM 3PIJ Chain:A ((33-513)) ---------------------AKRNNRWYPKYHIASNGGWINDPNGLCFYKGRWHVFYQLHPYGTQWGPM-HWGHVSSTDMLNWKREPIMFAPSLEQEKDGVFSGSAVIDDNGDLRFYYTGHRWANGHDNTGGDWQVQMTALPDNDELTSATKQGMIIDCPTDKVDHHYRDPKVWKTGDTWYMTFGVSSADKRGQMWLFSSKDMVRWEYERVLFQH----PDPDVFMLECPDFSPIKDKDGNEKWVIGFSAMGSKPSGFMNRNVSNAGYMIGTWEPG-GEFKPETEFRLWDCGHNYYAPQSFNV-DGRQIVYGWMSPFVQP---IPMEDDGWCGQLTLPREITLGDDGDVVTAPVAEMEGLREDTLDHGSVTLDM-DGEQIIADDAEAVEIEMTIDLAASTAERAGLKIHATEDGAYTYVAYDGQIGRVVVDRQAMANGDRGYRAAPLTDAELASGKLDLRVFVDRGSVEVYVNGGHQVLSSYSYASEGPRAIKLVAESGSLKVDSLKLHHMK

General information: TITO was launched using: RESULT: Template: 3PIJ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2602 -18363 -7.06 -41.08 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain A : 0.76 3D Compatibility (PKB) : -7.06 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.76 QMean score : 0.494

(partial model without unconserved sides chains): PDB file : Tito_3PIJ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3PIJ-query.scw PDB file : Tito_Scwrl_3PIJ.pdb: