Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSVYKHAPSRVRLRQTRSTVVKGRSGSLSWRRVRTGDLGLAVWGGREEYRAVKPGTPGIQPKGDMMTVTVVDAGPGRVSRSVEVAAPAAELFAIVADPRRHRELDGSGTVRGNIKVPAKLVVGSKFSTKMKLFGLPYRITSRVTALKPNELVEWS-HPLGHRWRWEFESLSPTLTRVTETFDYHAAGAIKNGLK-----FYEMTGFAKSNAAGIEATLAKLSDQYARGRA------ 2M47 Chain:A ((1-163)) -----------------------------------------------------------------------MPKSLTFEDSINIAAPINQVYALVSDITRTGEWSPV-CEKCWWDEDEGPVVGAHFTGRNVTPERTWETRSEVIVAEPNRCFGWSVTDGNVKWIYSMEPL-EEGTVLTESWEFTPKGQRFFHDKFGDKSIEEIEKRRLAAITGIPETLVAIQRILEVELEHHHHHH

General information: TITO was launched using: RESULT: Template: 2M47.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -21589 for 991 contacts (-21.8/contact) + 2D Compatibility (PS) -16302 + (NN) -7708 + (LL) 3812 1D Compatibility (HY) -6000 + (ID) 1600 Total energy: -49387.0 ( -49.84 by residue) QMean score : 0.327

(partial model without unconserved sides chains): PDB file : Tito_2M47.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2M47-query.scw PDB file : Tito_Scwrl_2M47.pdb: