Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSLLDIKNLSVRFGDTTAVPVVDGLDLSVDKGEVLAIVGESGSGKSVTMMALMGLIDAPGWVSADHLRFDGHDMLTLKGRQRRRIVGKDMAMVFQDPMTALNPSYTVGYQIEEVLRLHLGLRGK--ALRQRALELLERVEIPAAASRLDAYPHQLSGGMSQRVAIAMAIAAEPKLLIADEPTTALDVTIQAQIMELLLNLQRDQDMALILITHDLAVVAETAQRVCVMYAGEAVEIGGVPALFDRPTHPYTEALIKAIPEHCAGEARLATLPGIVPGRYDRPRGCLLSPRCPYAQEHCRQERPALETHERGAVRCFYPLNLLNEVA 4FWI Chain:B ((16-303)) ----------VREGTIKAA---DGISLDILENSVTAIVGESASGKSTIIEAMTKTLPPNGRILSGRVLYKGKDLLTMREEELRKIRWKEIALVPQAAQQSLNPTMKVIEHFKDTVEAH-GVRWSHSELIEKASEKLRMVRLNPEAV-LNSYPLQLSGGMKQRVLIALALLLDPVVLILDEPTSALDVLTQAHIIQLLKELKKMLKITLIFVTHDIAVAAELADKVAVIYGGNLVEYNSTFQIFKNPLHPYTRGLINSIM----------PIPGDPPSLLNPPSGCRFHPRCEYAMEICKKEKP-----------------------

General information: TITO was launched using: RESULT: Template: 4FWI.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -183817 for 2159 contacts (-85.1/contact) + 2D Compatibility (PS) -30442 + (NN) -20479 + (LL) 4092 1D Compatibility (HY) -20000 + (ID) 5750 Total energy: -256396.0 ( -118.76 by residue) QMean score : 0.444

(partial model without unconserved sides chains): PDB file : Tito_4FWI.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4FWI-query.scw PDB file : Tito_Scwrl_4FWI.pdb: