@TOME V3
(Apr 2019)

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Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : A9GMF3_SORC5: (2019-01-26 )
MTRDALDRAAVTAFLVARHGDAVCDSAIEIRPLPGGLCSEVALVTARLRGAAGARRVTLVAKLVHGTAAREAAVYRRLSRSVGRRFSPELLGAERLGRGRWLLYLERIEPAHAWPWADSGHTARVLERLARLHEETPQGAALPAWDYEAENLAMARDTLSLAERLPRGEVPALARALPALRRVVSALPAMRRQLLAFQPLGRAVIHGDVHPGNVMVRRRDGVVEPVLLDWARARMGSPLEDVSSWLQALGYWEPEARRRHDTLLAGYLSARGLPPALTRPLRDVYWFASASNALAGALGHHLAMACGASAPGVLAAAARNAADWLRVIRRADACWS

Atome Classification :

(22 SA) --------------.........10........20--..---...---....30........40..-..---....50-........60-----.-..--.-----.-----...----------.70........80.-.....-...90.....----------..------.100--.........---110.-....-----.-------------.----------------.-120....-...130.......-------------.140...-...----.150-.-...-.-...160------...-----..----.-.170---......-----...180.......190.....---...200-.......210.....-..220---........230.......240..-..----------------...----------250.-----------------.-...----...--------------260.-....--..270--.......280--.........290-.......300.......310--.....---...320.......330....---------------------
(Atome) (Ident) (Tito) (Num) (QMean) (Ligand) (Uniprot) --------------MTRDALDRAAVTAFLVARHG---DA---VCD---SAIEIRPLPGGLCSEVAL-VT---ARLRGA-AGARRVTLV------A-KL--V-----H-----GTA----------AREAAVYRRLSR-S-VGRRF-SPELLGAERL----------GR------GR----WLLYLERIE---P-AH-AWPW-----A-------------D----------------S-GHTARVL-ERLAR-LHEETPQ-------------GAALPAW-DYE----AE-N-L-AMA-R-DTLSLA------ERL-----PR----G-EV-----PALARA-----LPALRRVVSALPAM-RRQLLA---FQPLGR-AVIHGDVHPGNVMVR-RRDG----VVEPVLLDWARARMGSPLEDVSS-WL----------------QAL----------GY-W-----------------E-PEA----RRR--------------HDTL-LAGY--LSARG--LPPALTRP----LRDVYWFASASN-ALAGALGHHLAMACGASAP---GVLAA---AARNAADWLRVIRRADACWS---------------------
30 Fugue 79.7415% -31 - C3 - - 3ATS Y3168_MYCTU A:[1-357] ------------------TLPAVISRWLSSVLPG---GA---APE---VTVESGVDSTGMSSETII-LT---ARWQQD-GRSIQQKLV------A-RV--A-----P-----AAEDVPVFPTYRLDHQFEVIRLVGE-L-TDVPV-PRVRWIETTG----------DVL-----GT----PFFLMDYVEGVVP-PD-VMPY-----TFGDNWFADAPAERQ----------------R-QLQDATV-AALAT-LHSIPNA-------------QNTFSFLTDTT----LH-R-H-FNW-V-RSWYDF------AVE-----GI----G-RS-----PLLERT-----FEWLQSHWPDDAAA-REP-------------VLLWGDARVGNVLYR-DF-------QPVAVLDWEMVALGPRELDVAW-MI----------------FAH----------RV-F-----------------Q-ELA----GLA--------------TLPG-LPEV--MREDD--VRATYQALTGVELGDLHWFYVYSG-VMWACVFMRTGARRVHFGE---IEKPD---DVESLFYHAGLMKHLLGEEH---------------------
39 Fugue 79.4916% -31 - C3 - - 2PPQ - KHSE_AGRFC A:[5-320] -----------------TDITEDELRNFLTQYDV---GS---LTS---YKGIAENSNFLLHTTKDP-LI---LTLYEK-KNDLPFFLG------LMQH--L-----A-----AKG----------LSCPLPLPRKDG-E-LLGEL-S---------------------------GR----PAALISFLE---GMWL-RKP--------------------E----------------A-KHCREVG-KALAAMHLASEGF-------------EIKRPNA-LSV----DG-W-K-VLW-D-KSEERA------DEV-----EK----G-LR-----EEIRPE-----IDYLAAHWP----------------KDLPA-GVIHADLFQDNVFFL----G----DELSGLIDFYFACNDLLAYDVSI-CL----------------NAW----------CF-E-----------------K-DGAYN--VTK--------------GKAL-LEGY--QSVRP--LSEAELEA----LPLLSRGSALRF-FLTRLYDWLTTPAGALVVK---KDPLE---YLRKLRFHRTIANVAEYGLA---------------------
44 HHSearch 78.0019% -37 - C3 - - 2PPQ - KHSE_AGRFC A:[5-263] -----------------TDITEDELRNFLTQ-YD---V----G-----SLTSYKGIAE---NSNFL-LH---TTK---------DPLI------L-TLY-EK----K-----NDL----------PFFLGLMQHLAA-K---GLS-CPLPLPRKDGELLGE-----LS------GR----PAALISFLE-----GM-WLRK-----P-------------E----------------A-KHCREVG-KALAA-MHLASEG-------------FEIK-RP-N------A------LSV-D-GWKVLW------DKS-----EERA--D-EV-----EKGLR----------EEIRPEIDYL-AAH--W---PKDLPA-GVIHADLFQDNVFFL-G-D------ELSGLIDFYFACNDLLAYDVSI-CL----------------NAW----------CF-EKDGAY------------N-VTK----GKA-----------------L-LEGY--QSVRP--LSEAELE-----------------------------------------------------------------------------------------
41 Fugue 75.2017% 10 - C3 - - 3CSV ? A:[4-333] --------------------SREDEIRDFLATHG---YA---DWN---RTPRYQRLRSPTGAKAVLMDW---SPEEGG-DTQPFVDLA------Q-YL--R-----N-----LDI------------------SAPE-I-YAEEH-ARGLLLIEDL----------GD------AL----FTEVINNDP---A-Q------------------------------------------EMPLYRAAV-DLLIH-LHDAQTP-------------ELARLDP-ETL----SEMT-R-LAF-S-E----------------------------------YRYAIL-----GDAAEDNRKRFEHR-FAQILS---AQLEGDMVFVHRDFHAQNLLWLPEREG----LARVGVIDFQDAKLGHRAYDLVS-LL----------------QDA-------------------------------R-RDV----PAQ--------------VEAQMIDHY--IQATG--VD---ESH----FRSAYAVIAVQR-NM-RILGIFARLSQRFGKR---HYIEF---VPRVWAHFERGLAHPALASAAEEILNALPAPAPEVLERLRA
31 Fugue 74.5813% -1 - C3 - - 1ZYL - SRKA_ECOLI A:[4-328] ------------SAFTFQTLHPDTIMDALFEHGI---R----------VDSGLTPLNSYENRVYQF-QD-------ED-RRRFVVKFYRP----E-RW--T-----A-----DQI----------LEEHQFALQLVN-D-EVPVA-APVAFNGQTL----------LNH-----QG----FYFAVFPSV---G-GR-QFEA-----D-------------N----------------I-DQMEAVG-RYLGR-MHQTGRK-------------QLFIHRP-TIG----LN-E-YLIEP-R-KLFEDA------TLI-----PS----G-LK-----AAFLKA-----TDELIAAVTAHWR------------EDFTV-LRLHGDCHAGNILWR-DGPM----FV-----DLDDARNGPAVQDLW--------------------MLL----------NG-D-----------------K-AEQ----RMQ--------------LETI-IEAY--EEFSE--FDTAEIGL----IEPLRAMRLVYY-LAWLMRRWADP---AFPKN---FPWLT---GEDYWLRQTATFIEQAKVLQEPPLQLTPMY-----------
66 HHSearch 74.3715% -8 - C3 - - 5FTG CHKA_HUMAN A:[4-309] ----------------PEPRTRRRAYLWCKEFLP---GA---WRGLREDEFHISVIRGGLSNMLFQ-CS---LPDTTATLGDEPRKVL------L-RLYG------------EAM----------VLESVMFAILAE-R---SLG--PKLYGIFP-------------------------QGRLEQFIP-----SR-RLDT-----E-------------ELSL-------------P-DISAEIA-EKMAT-FHGMKMP-------------FNKEPK----------W-L-F-GTM-E-KYLKEV------LRI-----KF----T-EESR---IKKLHK------LLSYNLPLELENL-RSL-LE---STPSPV-VFCHNDCQEGNILLL-E-GRENSEKQKLMLIDFEYSSYNYRGFDIGN-HF----------------CEW----------MY-DYSYEKYPFFRANIRKYPT-KKQ----QLH-----------------F-ISSY--LPAFQ--N-----------------------------------------------------------------------------------------------
28 Fugue 73.6912% -17 - C3 - - 1NW1 - CKA2_CAEEL A:[32-426] GMKELLSTMDLDTDANTIPELKERAHMLCARFLGGAWKT---VPL---EHLRISRIKGGMSNMLFL-CRLSEVYPPIR-NEPNKVLLR------V-YF--N-----P-----ETE----------SHLVAESVIFTL-L-SERHL-GPKLYG--IF----------SG------GR----LEEYIPSRP---L-SC-H-EI-----S-------------L----------------A-HMSTKIA-KRVAK-VHQLEVP-------------IWKEPD--YLC----EA-L-Q-RWL-K-QLTGTV------DAE-----HR----F-DL-----PEECGV-----SSVNCLDLARELEF-LRAHIS---LSKSPV-TFCHNDLQEGNILLP-KR---------LVLIDFEYASYNYRAFDFAN-HF----------------IEWTIDYDIDEAPFY-K-----------------I-QTENFPENDQ--------------MLEF-FLNY--LREQGNTRENELYKK----SEDLVQETLPFV-PVSHFFWGVWGLLQVELSP---VGFGF---ADYGRDRLSLYFKHKQLLKNLA-------------------
29 Fugue 70.7910% -20 - C3 - - 3I1A ? A:[3-330] ----------------KQPIQAQQLIELLKVHYG---ID---I-----HTAQFIQGGADTNAFAYQ-AD---SE-----SKSYFIKLK------Y-GY--H-----D-----EIN----------LSIIRLLHDSGI-K-EIIFP-IHTLEAKLFQ----------QL------KH----FKIIAYPFI---H-AP-NGFT-----Q-------------NLT--------------G-KQWKQLG-KVLRQ-IHETSVP-------------ISIQQQL-RKE----IY-S-P-KWR-E-IVRSFY------NQIEFDNSDD----K-LT-----AAFKSF-----FNQNSAAIHRLVDT-SEKLSKKIQPDLDKY-VLCHSDIHAGNVLVG-NEES-------IYIIDWDEPMLAPKERDLMF-IG----------------GGV----------GN-------------------V-WNK----PHE--------------IQYF-YEGYGEINVDK--TILSYYRH----ERIVEDIAVYGQ-DLLSRNQN-----------------NQ---SRLESFKYFKEMFDPNNVVEIAFATE---------------
65 HHSearch 69.9815% 6 - C3 - - 5FUT CHKA_HUMAN A:[4-309] ----------------PEPRTRRRAYLWCKEFLP---GA---WRGLREDEFHISVIRGGLSNMLFQ-CS---LPDTTATLGDEPRKVL------L-RLYG-------GA---EAM----------VLESVMFAILAE-R---SLG--PKLYGIFP-------------------------QGRLEQFIP-----SR-RLDT-----E-------------ELSL-------------P-DISAEIA-EKMAT-FHGMKMP-------------FNKEPK----------W-L-F-GTM-E-KYLKEV------LRI-----KF----T-EESR---IKKLHK------LLSYNLPLELENL-RSL-LE---STPSPV-VFCHNDCQEGNILLL-E-GRENSEKQKLMLIDFEYSSYNYRGFDIGN-HF----------------CEW----------MY-DYSYEKYPFFRANIRKYPT-KKQ----QLH-----------------F-ISSY--LPAFQ--N-----------------------------------------------------------------------------------------------
45 HHSearch 69.4616% -11 - C3 - - 6EF6 ? A:[27-303] ---------------------DVTIAQQALTHYD---V----S-----DNASLRLL-NLSENATYL-VE---DGE---------HQSI------L-RVH-RQDYHQP-----HEI----------ESELDWLAALRTDS---DVT-VPTVVPARDGRRVVTVDPAD-V------PR----HVVHFEMVG-----GA-EPDE-----ESL-----------T----------------L-DDFQTLG-RITAS-LHEHSQR-------------WTRPAGF-GRFSWDWEH-C-L-GDT-P-RWGRWQ------DA------------E-GV-----GASETA-------LLTRAQDLLHRK-LEE-YG---SGPDRY-GLIHADLRLANLLVD-S-STP---QRTITVIDFDDCGFGWYFYDFGT-AV----------------SFI----------EH-DPR---------------L-GEW----QES-----------------W-VAGY--RSRRE--LPAADEAM----L-----------------------------------------------------------------------------------
49 HHSearch 69.4514% -44 - C3 - - 3I1A ? B:[2-272] ---------------LKQPIQAQQLIELLKVHYG---I----------DIHTAQFIQGGADTNAFA-YQ---ADSE---S----KSYF------I-KLK-Y-----G-----YHD----------EINLSIIRLLHD-S---GIKEIIFPIHTLEAKLFQQ-----LK------HF----KIIAYPFIH-----AP-NGFT-----QNL-----------T----------------G-KQWKQLG-KVLRQ-IHETSVP-------------ISIQQQL-RK-----EI-Y-S-PKWRE-IVRSFY------NQI-----EFDNSDD-KL-----TAAFKSFFNQNSAAIHRLVDTSEKL-SKK-IQ---PDLDKY-VLCHSDIHAGNVLVG-N-E------ESIYIIDWDEPMLAPKERDLMF-IG----------------GGV----------GNVW-----------------NKPHE----IQY-----------------F-YEGY--GEINV--------------------------------------------------------------------------------------------------
70 SP3 68.4911% 0 - C3 - - 1NW1 - CKA2_CAEEL A:[32-426] GMKELLSTMDLDTDANTIPELKERAHMLCARFLG---GAWKTVPL---EHLRISRIKGGMSNMLFL-CR---LSEVYP-PIRNEPNKVLLRVYFN-PE--T-----E-----SHL----------VAESVIFTLLSE-R-HL-GP-KLYGIFSG---------------------------GRLEEYIP---S-RP-LSCHEI---S-------------L----------------A-HMSTKIA-KRVAK-VHQLEVP-------------IW------KEP----DY-L-C-EAL-Q-RWLKQL------TGT-----VD----A-EHRFDLPEECGVS-----SVNCLDLARELEFL-RAHI-S---LSKSPV-TFCHNDLQEGNILLP-KR---------LVLIDFEYASYNYRAFDFAN-HF----------------IEW----------TI-D-----------------Y-DID----EAPFYKIQTENFPENDQMLEF-FLNY--LREQGNTRENELYKK----SEDLVQETLPFV-PVSHFFWGVWGLLQVELSPVGFGFADY---GRDRLSLYFKHKQLLKNLA----------------------
63 HHSearch 63.6319% -13 - C3 - - 5IGH - ? A:[5-257] -----------------TTADTSQLYALAAR-HG---L----KLH-----GPLTVNELGLDYRIVI-AT---VDD----G----RRWV------L-RIPRRAEV--S-----AKV----------EPEARVLAMLKN-R--LPFA-VPDWRVANAE----------LV------AYPMLEDSTAMVIQP-----GS-STPDWVVPQD-------------S----------------E-VFAESFA-TALAA-LHAVPIS-------------AAVDAGM-LI-----RT-P---TQARQ-KVADDV------DRV-----R-----R-EF-----V-VNDK-------RLHRWQRWLDDD-S--------SWPDFS-VVVHGDLYVGHVLID-N-TE-----RVSGMIDWSEARVDDPAIDMAA-HL----------------MV--------------F-----------------G-EEG----LAK-----------------L-LLTY--EAAGG--R-----------------------------------------------------------------------------------------------
64 HHSearch 62.5816% -16 - C3 - - 1ZYL - SRKA_ECOLI A:[9-263] -----------------QTLHPDTIMDALFE-HG---I----RVD-----SGLTPL-NSYENRVYQ-FQ---DED----R----RRFV------V-KFY-RPERWTA-----DQI----------LEEHQFALQLVN-D---EVP-VAAPVAFNGQTLLN------HQ------GF----YFAVFPSVG-----GR-QFEA-----D-------------N----------------I-DQMEAVG-RYLGR-MHQTGRK-------------QLFIHRP-T------IG-L---NEYLI-EPRKLF------EDA-----------T-LI-----PSGLKA------AFLKATDELIAAV-TAH--W---REDFTV-LRLHGDCHAGNILWR-D---------GPMFVDLDDARNGPAVQDLWM-LL----------------NGD----------KA-E-----------------Q-RMQ----LET-----------------I-IEAY--EEFSE--FDTAEI------------------------------------------------------------------------------------------
46 HHSearch 62.2218% -28 - C3 - - 5UXD ? A:[3-255] -----------------MPEDLDALLDLAARHGL---D------L---DGGTLRTEEIGLDFRVAF-AR---AHD----G----GDWV------L-RLP-RRPDV-L-----ERA----------AVEGRLLAMLAP-H--LDVA-VPDWRIST---------------------S----ELIAYPLLP-----GS-PGLT-----V-------------AADGEVSWHVDMAS---T-VYARSLG-SVVAQ-LHAVDAE-------------AAAATGI-EV-----RS-P---AQVRG-AWRQDL------ARV-----GA----EFEI-----APA----------LRERWEAWLADD-G--------CWPGHS-VLTHGELYPAHTLVE-D-E------RITAVLDWTTAAVGDPAKDLMF-HQ----------------V------------S--A-----------------P-SAI----FEV-----------------A-LQAY--AEGGG--RP----------------------------------------------------------------------------------------------
33 Fugue 62.209% -3 - C3 - - 2Q83 COTI_BACSU A:[11-346] --------------LSAEDAKKLTELAENVLQGW---DV---QAE---KIDVIQA------------LV---WKVHTD-SGAVCLKRI------H-RP--E-----K-----KAL----------FSIFAQDYLAKK-GMNVPGI-LPNKKGSLYS----------KH------GS----FLFVVYDWI---E-GR-PFEL-------------------T----------------V-KQDLEFIMKGLAD-FHTASVGYQPPNGVPIFTKLGRWPNHY-TKR----CK-QME-TWK-LMAEAEKE------DPF-----SQ----L-YL-----QEIDGF-----IEDGLRIKDRLLQSTYVPWTE---QLKKSP-NLCHQDYGTGNTLLG-ENE-------QIWVIDLDTVSFDLPIRDLRKMII----------------PLL----------DT-------------------T-GVW----DDE--------------TFNVMLNAY--ESRAP--LTEEQKQVM---F---------IDMLFPYELYDVIREKYVRKSA---LPKEE---LESAFEYERIKANALRQLI----------------------
35 Fugue 61.0712% 1 - C3 - - 2OLC MTNK_BACSU A:[5-396] ------------KTPLYETLNESSAVALAVKLGL---T------------LTCQEIGDGNLNYVFH-IY---DR---A-LIIKQAVPY------W-PL--T-----I-----DRA----------RIESSALIRQGE-H-VPHLV-PRVFYSDTEM----------AVTVMEDLSH----LKIARKGLI---E-GE-NYPH-----L-------------S----------------Q-HIGEFLG-KTLFY-SSDYALE-------------PKVKKQL-VKQ----FT-N-P-ELC-D-ITERLVFTDPFFDHD-----TN----D-FE-----EELRPF-----VEKLWNNDSVKIEA-AKLKKS---FLTSAE-TLIHGDLHTGSIFAS-EH--------ETKVIDPEFAFYGPIGFDVGQ-FIANLFLNALSRDGADREPLY----------EH-V-----------------N-QVW----ETF--------------EETF-SEAW--QKDSL--DVYANIDG----YLTDTLSHIFEE-AIGFAGCELIRRTIGLAHV---ADLDTIVPFDKRIGRKRLALETGTAFIEKRSEFKTITDVIELFKLLVK-
47 HHSearch 60.3817% 1 - C3 - - 3CSV ? A:[4-256] -------------------SREDEIRDFLAT-HG----------Y---ADWNRTP--------RYQRLR---SPT----G----AKAV------L-MDW-SPEE--G-----GDT----------QPFVDLAQYLRN-L---DIS-APEIYAEEH-------------------AR----GLLLIEDLG-----DA-LFTE-----V-------------INNDPAQE---------M-PLYRAAV-DLLIH-LHDAQTP-------------ELA--RL-DP-----ET-L-S-EMTRL-AFSEYR------YA--------------IL-----GDAAED-------NRKRFEHRFAQI-LSA------QLEGDM-VFVHRDFHAQNLLWL-P-EREG--LARVGVIDFQDAKLGHRAYDLVS-LL----------------QDA----------RRDV-----------------P-AQV----EAQ-----------------M-IDHY--IQATG--VDES--------------------------------------------------------------------------------------------
59 HHSearch 60.1517% -23 - C3 - - 5UXA - ? A:[3-257] -------------------KDIKQVIEIAKKHNL---------FL---KEETIQFNESGLDFQAVF-AQ---DNN----G----IDWV------L-RLP-RREDV-M-----PRT----------KVEKQALDLVNK-Y-AISFQ-APNWIIYT---------------------E----ELIAYKKLD-----GV-PAGT-----I-------------DHNIGNYIWEIDINNVPE-LFHKSLG-RVLAE-LHSIPSN-------------KAAALDL-VV-----HT-P---EEARM-SMKQRM------DAV-----R-----A-KF-----G-VGEN-------LWNRWQAWLNDD------D---MWPKKT-GLIHGDVHAGHTMID-K-DA-----NVTGLIDWTEAKVTDVSHDFIF-NY----------------R------------A--F-----------------G-EEG----LEA-----------------L-ILAY--KEIGG--Y-----------------------------------------------------------------------------------------------
58 HHSearch 59.9417% -20 - C3 - - 5IWU ? A:[3-257] -------------------KDIKQVIEIAKKHNL---------FL---KEETIQFNESGLDFQAVF-AQ---DNN----G----IDWV------L-RLP-RREDV-M-----PRT----------KVEKQALDLVNK-Y-AISFQ-APNWIIYT---------------------E----ELIAYKKLD-----GV-PAGT-----I-------------DHNIGNYIWEIDINNVPE-LFHKSLG-RVLAE-LHSIPSN-------------KAAALDL-VV-----HT-P---EEARM-SMKQRM------DAV-----R-----A-KF-----G-VGEN-------LWNRWQAWLNDD------D---MWPKKT-GLIHGDVHAGHTMID-K-DA-----NVTGLIDWTEAKVTDVSHDFIF-NY----------------R------------A--F-----------------G-EEG----LEA-----------------L-ILAY--KEIGG--Y-----------------------------------------------------------------------------------------------
62 HHSearch 58.6119% -10 - C3 - - 5IGI ? A:[5-257] -----------------TTADTSQLYALAAR-HG---L----KLH-----GPLTVNELGLDYRIVI-AT---VDD----G----RRWV------L-RIPRRAEV--S-----AKV----------EPEARVLAMLKN-R--LPFA-VPDWRVANAE----------LV------AYPMLEDSTA-VIQP-----GS-STPDWVVPQD-------------S----------------E-VFAESFA-TALAA-LHAVPIS-------------AAVDAGM-LI-----RT-P---TQARQ-KVADDV------DRV-----R-----R-EF-----V-VNDK-------RLHRWQRWLDDD-S--------SWPDFS-VVVHGDLYVGHVLID-N-TE-----RVSGMIDWSEARVDDPAIDMAA-HL----------------MV--------------F-----------------G-EEG----LAK-----------------L-LLTY--EAAGG--R-----------------------------------------------------------------------------------------------
56 HHSearch 53.5815% 7 - C3 - - 4R78 ? A:[18-253] -----------------GSHMEKIIKEKISSLLS---QE-----E---EVLSVEQL-GGMTNQNYL-AK---TTN---------KQYI------V-KF--FG----KGTEKLINR----------QDEKYNLELLKD-L---GLD-VKNYLFDI--------------------EA----GIKVNEYIE-----SAITLDS-----T-------------SI---------------K-TKFDKIA-PILQT-IHTSAKE-------------LRG--E---------FA-P-F-EEI-K-KYESLI------EEQ--------------I-----PYA----------NYESVRNAVFSL-EKR-LA---DLGVDR-KSCHIDLVPENFIES-P-Q------GRLYLIDWEYSSMNDPMWDLAA-LF----------------LES-----------E-F-----------------T-SQE----EET-----------------F-LSHY--ESDQT--------------------------------------------------------------------------------------------------