@TOME V3
(Feb 2022)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
3D Alignment Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
3D Alignment Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
PDB Ligands
Affinity Score
Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
Sequence Alignment
Tab of Complexes
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : C5FE38_ARTOC: (2019-01-26 )
MSDAMTQGNFVYAFLKSCFTRLRGFAQFLLPFLRPKKRRGINYYNPVELNKYAMQTLQKALKDDPGADIRDCLPLVYNSAMRVISKTKARKEEELKRPPTPEFRTKINYVENAEIIFPLSDEVVSLLLQYSDKDGELVGKQLVISLKQLIWESPKIWESAVRGVVLKCSDNVALKVIRQHPDYTEYTTLQYLAEKLPEIPVPSTYGVIRFKPFTAYFMSYIPSMTLAEAWPSLNHEGKTSVQEQLEEIFSKLRTLRKDDGYPLGGVGGEGVKEARVGNSAQEKTINTAASFVDLQFSLSEFLSKSYIQFIRTLQPPPPTGSVFTHGDVRKDNIMVDIGDNNTCTVTAIIDWEDAGFYPDYFECTTLTRTWLPHVEDDWYNYLPPCIDPARFPHHWLIDRLWGIHHPIF
Atome Classification :
(20 SA)
------.........10.------------.......20--------------------.........30-......---...40..--..-....50........60........70......-..80........90........100........110.......120.......130.--...-...140----........150-........160......----.-----170--.....--...---.---180-------..----.---------......190..---...-..200.......-210--........220.....-.-.230--------..--------......240.......250.-......260-----------.......270.......280.-----......290......--.-300.......310...---.--...320.......330.......340......-------.350........360--.......370---------------..-----....--...380....-------...390---...-.....400..-....----------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
------MSDAMTQG
N
F
V
Y
------------
A
F
L
K
S
C
F
T
---------------------
R
L
R
G
F
A
Q
F
L
L
--
P
F
LR
P
K
---KRRGINY--YN-
P
V
E
L
N
K
Y
A
M
Q
T
L
Q
K
A
LKDDPG
A
D
I
R
D
C
L
P
L
V
Y
-
N
S
A
M
R
V
I
S
K
T
KA
R
K
E
E
E
LKRPPTP-
E
F
R
T
K
I
NYVEN
A
E
I
I
F
PL
S
D
E
V
V
S
L
L
L
QYSDK--D
G
E
-
L
V
G
K
Q
-----
L
V
I
S
L
K
Q
L
IW--ES
P
K
I
W
E
S
A
VR
G
V
V
L
KC----S-----D----
N
V
A
L
K
--
V
I
R
---Q---H---------PD----Y---------T
E
Y
T
T
L
Q
Y
L
A
E
---KLP-EIPVPST
Y
G
V
I
R
-
F
K
---
P
F
T
A
Y
F
M
S
YIPS
M
T
L
A
-
E
-
A
W
P---------SL--------NHEG
K
T
S
V
Q
E
Q
L
E
E
I
F
S
K
L
R
-
T
L
R
KDDGYP-----------LGGVGGEG
V
K
E
ARVGNS
A
Q
E
K
-----
T
INTA
A
S
F
V
D
L
Q
F
S
L
--
S
-
E
F
L
S
K
S
Y
I
Q
F
I
R
TLQP---P--PPTGS
V
F
THGDVRKD
N
I
M
V
D
IGDNN
T
C
T
V
T
A
I
-------
I
DW-EDAGFYPD
Y
F
E
--
C
T
T
L
T
R
TW-----------------LP-----HVED--
D
W
YNYLPPCI-------DPARF----
P
H
H
-
W
L
I
D
R
L
W
GIH-HPIF----------------------------------------------
27
Fugue
80.22
14%
-15
- C5 -
-
4DGK
5
CRTI_PANAN
A:
[1-492]
------
M
K
P
T
T
V
I
G
A
G
F
G
------------
G
L
A
L
A
I
R
L
---------------------
Q
A
A
G
I
P
V
L
L
L
--
E
Q
R
Y
V
Y
---
E
D
Q
G
F
T
F
--
D
A
G
P
T
V
I
---
T
D
P
S
A
I
E
E
L
F
A
L
A
G
K
Q
L
K
E
Y
V
E
L
L
P
V
T
P
F
Y
R
L
C
W
E
S
G
K
V
F
N
Y
D
----------
N
D
Q
T
R
L
E
A
Q
I
Q
Q
F
N
P
R
D
V
E
G
Y
R
Q
F
L
D
Y
S
R
A
V
F
K
E
G
-
Y
L
G
T
V
-----
P
F
L
S
F
R
D
M
L
R
--
A
A
P
Q
L
A
K
-------
L
Q
A
----
W
-----
R
----
S
V
Y
S
K
--
V
A
S
---
Y
---
I
---------
E
D
----
E
---------
H
L
R
Q
A
F
S
F
H
S
L
---
L
V
G
-
G
N
P
T
S
S
I
Y
T
L
I
H
-
A
L
E
R
-
E
W
G
V
W
F
P
R
-----------------------------------
G
G
T
G
A
L
V
Q
G
M
I
K
L
F
Q
D
L
G
G
E
V
V
L
N
A
R
V
S
-----------
H
M
E
T
T
G
N
K
I
E
A
V
H
L
E
D
G
R
R
F
L
T
Q
A
V
A
S
N
A
D
S
N
S
L
F
V
L
Y
F
G
L
--
N
-
H
H
H
D
Q
L
A
H
H
T
V
C
F
G
P
R
---
L
--
A
E
D
F
S
L
Y
L
H
A
P
C
V
T
D
S
S
L
A
P
E
G
C
G
S
Y
Y
V
L
A
P
V
P
H
LGTAN
L
D
W
-
T
V
E
G
P
K
L
R
D
R
I
--
F
A
Y
L
E
Q
H
Y
-----------------
M
P
-----
G
L
R
S
QL
V
T
H
R
M
F
T
P
-
F
-------
D
F
R
T
I
----
T
N
L
-
Y
L
V
G
A
--
G
I
P
-
G
V
I
G
S
A
K
A
T
A
G
L
M
L
E
D
L
I--------------------------------
21
Fugue
77.34
16%
-16
- C2 -
-
1J7L
1
KKA3_ENTFL
A:
[2-264]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
K
M
-
R
I
S
P
E
-----
L
K
K
L
I
E
K
Y
R
C
--
V
K
D
T
E
G
M
S
P
A
--
K
V
Y
K
L
----
V
-----
G
----
E
N
E
N
L
--
Y
L
K
---
M
---
T
---------
D
S
----
R
YKGTTYD
V
E
R
E
K
D
M
M
L
W
L
E
G
---
K
----
L
P
V
P
K
V
L
H
F
E
R
-
H
D
---
G
W
S
N
L
L
M
S
E
A
D
G
V
L
C
S
-
E
-
E
Y
E
---------
D
----------
E
Q
S
P
E
K
I
I
E
L
Y
A
E
C
I
R
L
F
H
-
S
I
D
I
S
D
C
-
P
-----------
Y
T
N
S
L
D
S
R
L
A
E
L
D
Y
L
L
N
N
D
L
A
-----
D
V
D
C
E
N
W
E
E
D
T
P
F
K
D
--
P
-
R
E
L
Y
D
F
L
K
T
------
E
---
K
--
P
E
E
E
L
V
F
S
H
G
D
L
G
D
S
N
I
F
V
K
D
G
-----
K
V
S
G
F
-------
I
D
L
-
G
R
S
G
R
A
D
K
W
Y
D
--
I
A
F
C
V
R
S
I
-----------------
R
E
D
IGEE
Q
Y
V
E
--
L
F
F
D
L
L
G
I
K
P
-------
D
W
E
K
I
----
K
Y
Y
-
I
L
L
D
E
L
F
------------------------------------------------------
26
Fugue
73.23
16%
6
- C5 -
-
5EZ7
1
Y4991_PSEAE
A:
[2-392]
------
M
P
Q
A
L
S
T
D
I
L
I
V
G
GG
I
A
-------
G
L
W
L
N
A
R
L
---------------------
R
R
A
G
Y
A
T
V
L
V
E
S
A
S
L
G
G
G
QSV
K
S
Q
G
I
I
H
GG
T
G
-
A
S
E
A
I
A
D
M
P
R
R
W
R
A
C
L
G
S
D
G
E
L
D
L
R
G
-
V
R
L
L
S
-
E
A
H
Y
L
W
S
P
V
E
Q
A
K
G
E
D
L
P
P
A
L
R
D
K
-
G
F
K
G
K
A
Y
R
L
T
--
E
I
V
F
----
D
V
P
D
L
I
R
R
L
A
E
L
--
A
G
D
S
L
L
A
G
E
-----
R
I
E
P
L
R
E
-----------
G
R
E
L
A
G
L
C
V
D
G
----
R
-----
E
----
I
R
A
Q
R
--
V
V
L
---
S
---
A
---------
G
A
----
G
---------
N
E
A
L
L
R
E
L
G
L
E
---
Q
P
A
-
M
Q
R
R
P
L
H
M
V
M
V
K
-
A
A
---
T
L
K
P
L
Y
A
H
C
L
G
A
-----------------------------
G
P
K
P
R
I
T
V
T
T
H
P
T
R
------------
D
G
Q
S
-----------
V
W
Y
L
G
G
D
I
A
E
T
D
G
V
A
R
D
E
A
A
Q
-----
I
A
E
A
R
R
E
L
A
K
L
L
P
W
I
--
D
---
L
G
Q
A
Q
W
A
T
L
R
V
D
R
A
---
E
--
P
A
Q
S
N
L
L
-----
R
P
D
N
A
F
L
A
E
Q
G
R
------
L
L
-------
V
G
W
P
T
K
L
A
L
A
P
D
F
A
D
R
V
C
A
R
L
E
E
D
G
-----------------
I
R
-----
P
S
E
H
--
A
----------------
A
L
P
Q
L
----
P
R
P
-
P
L
A
E
P
A
W
E
V
A
-
F
A
------------------------------------------------
22
Fugue
72.60
16%
-37
* C4 *
-
4WMA
2
XXLT1_MOUSE
A:
[7-305]
--------
V
V
P
V
D
Y
H
L
L
M
------------
M
F
----------------------------------------------------
T
K
A
--
E
H
-
N
A
P
L
Q
A
K
A
R
V
A
L
S
S
L
L
R
L
---
A
K
F
E
A
H
E
V
L
N
L
-
H
F
V
S
E
E
A
S
R
E
V
A
K
A
L
L
R
E
L
L
P
P
A
A
-
G
F
K
C
K
V
I
F
H
D
V
A
V
L
T
D
K
L
F
P
V
V
E
A
M
Q
K
Y
F
S
A
G
--
S
G
T
-
Y
Y
S
D
S
IFF--
L
S
V
A
M
H
Q
I
M
P
--
K
E
I
P
--------------------------------
R
--
I
I
Q
---
L
---
D
---------
L
D
----
L
---------
K
Y
K
T
N
I
R
E
L
F
E
---
E
F
D
-
N
F
L
P
G
A
V
I
G
I
A
R
-----------------------
E
-
M
Q
P
---------
V
Y
--------
R
H
T
--------
F
W
Q
F
R
H
E
N
P
-
K
T
R
V
G
D
P
P
P
-----------
E
G
L
P
G
----------------------
F
N
S
G
V
M
L
L
N
L
E
A
M
R
--
Q
----
S
P
L
Y
S
H
L
L
E
--------------
P
S
W
V
Q
Q
L
A
D
K
Y
H
F
R
G
H
L
G
D
Q
D
F
F
T
M
I
G
M
-------
E
H
P
-
E
L
F
H
V
L
D
C
T
W
N
---
R
Q
L
C
T
W
W
-----------------
R
D
-----
H
G
Y
S
--
D
V
F
Q
A
Y
F
R
C
E
-------
G
H
V
K
I
----
Y
H
G
-
N
C
N
T
P
I
P
E
-----------------------------------------------------
41
SP3
69.03
12%
-30
- C2 -
-
1NW1
-
CKA2_CAEEL
A:
[32-426]
---------------------------------------------------------------------------------------------------
G
M
K
E
L
L
S
T
M
--
D
L
D
T
D
A
N
T
-
I
P
E
L
K
-
E
R
A
H
M
L
C
A
R
F
L
G
---
G
A
W
K
T
V
P
L
E
-
H
--
L
R
I
S
R
I
K
G
G
-----
M
S
N
M
L
F
--
L
C
R
L
S
E
V
--
Y
P
P
-
I
R
N
E
---------------------------------------
P
-----
N
----
K
V
L
L
R
--
V
Y
F
---
N
---
P
---------
E
T
E
S
H
L
V
---------
A
E
S
V
I
F
T
L
L
S
E
---
R
H
L
-
G
---
P
K
L
Y
G
I
F
S
-
G
-------
G
R
L
E
E
Y
I
P
S
R
P
L
----------------
S
C
--------
H
E
I
S
L
A
H
M
S
T
K
I
A
K
R
V
A
K
V
H
-
Q
L
E
V
P
I
W
K
E
PD
Y
L
C
E
A
L
Q
R
W
L
K
Q
L
T
G
T
V
D
A
E
H
R
F
D
L
P
E
E
C
G
-----
V
-----------
S
S
V
--
N
-
C
L
D
L
A
R
E
L
E
F
L
R
A
H
I
S
---
L
--
S
K
S
P
V
T
F
C
H
N
D
L
Q
E
G
N
I
L
L
P
K
R
-------
L
V
L
-------
I
D
F
-
E
Y
A
S
Y
N
Y
R
A
F
D
--
F
A
N
H
F
I
E
W
T
IDYDIDEAPF
Y
K
I
Q
TE
N
F
-----
P
E
N
D
--
Q
M
L
E
F
F
L
N
Y
L
-------
R
E
Q
G
N
TREN
E
L
Y
-
K
K
S
E
D
L
V
Q
E
T
-
L
P
F
V
P
V
S
H
F
F
W
G
V
W
G
L
L
Q
V
ELSPVGFG
F
A
D
Y
G
R
D
R
L
S
L
Y
F
K
H
K
Q
L
L
K
N
LA
38
SP3
67.45
10%
-12
- C2 -
-
1ND4
1
KKA2_KLEPN
A:
[10-264]
-----------------------------------------------------------------------------------------------------------------------------------------------
G
S
P
--
A
-
A
W
V
E
R
L
F
G
Y
D
W
A
Q
Q
T
I
G
C
S
D
A
A
V
F
R
L
----
S
A
--
Q
G
---------------------------------------------
R
-----
P
----
V
L
F
V
K
--
T
D
L
SGA
L
---
N
---------
E
L
----
Q
---------
D
E
A
A
R
L
S
W
L
A
T
---
T
---
G
V
P
C
A
A
V
L
D
V
V
T
-
E
A
---
G
R
D
W
L
L
L
G
E
V
P
G
Q
D
-------
L
---------
L
S
--------
S
H
L
A
P
A
E
K
V
S
I
M
A
D
A
M
R
R
L
H
-
T
L
D
P
A
T
C
P
F
-----------
D
H
Q
A
K
H
---
R
I
E
R
A
R
T
R
M
E
A
G
-----
L
V
D
Q
----
D
D
L
D
E
E
H
--
Q
-
G
L
A
P
A
E
L
F
A
R
L
K
A
-
R
M
---
P
--
D
G
E
D
L
V
V
T
H
G
D
A
C
L
P
N
I
M
V
E
N
G
-----
R
F
S
G
F
-------
I
D
C
-
G
R
L
G
V
A
D
R
Y
Q
D
--
I
A
L
A
T
R
D
-------------------------
I
A
E
E
--
L
G
G
E
W
A
D
R
F
L
-------
V
L
Y
G
I
----
A
A
P
D
S
Q
R
I
A
F
Y
R
L
L
-
D
E
F
F
----------------------------------------------
51
HHSearch
67.33
18%
-17
- C2 -
-
4GKI
1
?
C:
[39-239]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
T
I
Y
R
L
----
Y
GKPNA
P
----
E
L
F
L
K
--
H
G
K
---
G
---
S
V
A
N
------
D
V
----
T
---------
D
E
M
V
R
L
N
W
L
T
A
-------
F
M
P
L
P
T
I
K
H
F
I
R
-
T
P
---
D
D
A
W
L
L
T
T
A
I
P
G
K
T
A
F
-
Q
-
V
L
E
---------
E
Y
--------
P
-
D
S
G
E
N
I
V
D
A
L
A
V
F
L
R
R
L
H
-
S
I
P
V
C
N
C
P
F
------------
N
S
D
---
R
V
F
R
L
A
Q
A
Q
S
R
M
N
N
-----
G
L
---
V
D
A
S
D
F
D
D
E
R
--
N
-
G
W
P
V
E
Q
V
W
K
E
M
H
K
L
L
P
------
F
S
P
D
S
V
V
T
H
G
D
F
S
L
D
N
L
I
F
D
E
G
-----
K
L
I
G
C
-------
I
D
V
-
G
R
V
G
I
A
D
R
Y
Q
D
--
L
A
I
L
W
N
C
L
-----------------
G
E
------------------------------------------------------------------------------------------------------
50
HHSearch
67.32
18%
-17
* C2 *
-
4GKH
2
?
A:
[39-239]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
T
I
Y
R
L
----
Y
GKPN
A
P
----
E
L
F
L
K
--
H
G
K
---
G
---
S
V
A
N
------
D
V
----
T
---------
D
E
M
V
R
L
N
W
L
T
A
-------
F
M
P
L
P
T
I
K
H
F
I
R
-
T
P
---
D
D
A
W
L
L
T
T
A
I
P
G
K
T
A
F
-
Q
-
V
L
E
---------
E
Y
--------
P
-
D
S
G
E
N
I
V
D
A
L
A
V
F
L
R
R
L
H
-
S
I
P
V
C
N
C
P
F
------------
N
S
D
---
R
V
F
R
L
A
Q
A
Q
S
R
M
N
N
-----
G
L
---
V
D
A
S
D
F
D
D
E
R
--
N
-
G
W
P
V
E
Q
V
W
K
E
M
H
K
L
L
P
------
F
S
P
D
S
V
V
T
H
G
D
F
S
L
D
N
L
I
F
D
E
G
-----
K
L
I
G
C
-------
I
D
V
-
G
R
V
G
I
A
D
R
Y
Q
D
--
L
A
I
L
W
N
C
L
-----------------
G
E
------------------------------------------------------------------------------------------------------
30
Fugue
67.18
16%
6
- C5 -
-
5L3T
-
THP1_YEAST
B:
[1-455]
MD
M
A
N
Q
L
L
D
E
L
A
H
G
N
F
S
H
LTLNLSQN
G
R
E
I
A
I
L
Q
K
Q
L
T
GFD
D
K
Q
L
E
T
F
V
E
Q
HPAMPND
T
R
F
K
I
M
C
T
S
F
L
--
N
Y
A
R
D
V
---
D
P
W
--
S
A
--
W
S
-
S
S
D
L
I
F
E
F
Y
Q
C
L
I
N
C
L
I
N
D
N
A
P
H
I
E
M
L
I
P
V
A
T
-
R
E
T
E
F
I
I
N
L
A
G
K
L
D
S
F
H
L
Q
L
H
T
-----
R
S
H
Q
F
L
S
H
I
S
S
I
L
S
R
L
F
N
S
I
K
P
P
--
R
G
N
A
S
--
S
T
N
-
I
P
G
K
Q
R
I
L
L
Y
L
V
N
K
L
N
N
I
Y
F
R
I
E
S
P
Q
L
C
S
N
I
F
K
N
F
Q
P
K
-----
S
-----
M
----
L
A
H
F
N
EY
Q
L
D
---
Q
---
Q
---------
I
E
----
Y
---------
R
Y
L
L
G
R
Y
Y
L
L
N
SQ
V
H
N
A
-
F
V
Q
F
N
E
A
F
Q
S
L
L
-
N
L
---
P
L
T
N
Q
A
I
T
R
N
G
T
R
I
L
N
-
Y
-
M
I
P
---------
T
G
--------
L
I
L
G
K
M
V
K
W
G
P
L
R
P
F
L
S
Q
E
T
-
I
D
N
W
S
V
L
Y
K
-----------
H
V
R
Y
G
N
--
I
Q
G
V
S
L
W
L
R
Q
N
E
R
-----
H
L
C
A
R
Q
L
L
I
V
L
L
E
K
L
--
P
-
M
V
T
Y
R
N
L
I
K
T
V
I
K
S
W
T
---
T
--
E
W
G
Q
N
K
L
P
Y
S
L
I
E
R
V
-
L
Q
L
S
I
G
P
T
F
E
D
P
G
A
Q
E
-------
I
T
I
-
Y
N
G
I
H
S
P
K
N
V
E
--
N
V
L
V
T
L
I
N
-----------------
L
G
-----
L
L
R
A
--
N
C
F
P
Q
L
Q
L
C
V
V
K
KTTM
I
Q
E
I
V
P
----
P
V
N
-
E
R
I
T
K
M
F
P
A
H
S
H
V
L
W
----------------------------------------------
67
HHSearch
64.56
18%
22
- C2 -
-
1ND4
1
KKA2_KLEPN
A:
[31-229]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
C
S
D
A
A
V
F
R
L
----
S
-----
A
Q
G
R
P
V
L
F
V
K
--
T
D
L
---
S
GAL
N
---------
E
L
----
Q
---------
D
E
A
A
R
L
S
W
L
A
T
---
T
---
G
V
P
C
A
A
V
L
D
V
V
T
-
E
A
---
G
R
D
W
L
L
L
G
E
V
P
G
Q
D
L
L
-
S
-
S
-----------
H
L
--------
A
---
P
A
E
K
V
S
I
M
A
D
A
M
R
R
L
H
-
T
L
D
P
A
T
C
P
------------
F
D
H
Q
A
K
H
R
I
E
R
A
R
T
R
M
---
E
A
-----
G
L
V
D
Q
D
D
L
D
E
E
H
Q
------
G
L
A
P
A
E
L
F
A
R
L
K
A
R
M
P
------
D
G
E
D
L
V
V
T
H
G
D
A
C
L
P
N
I
M
V
E
N
G
-----
R
F
S
G
F
-------
I
D
C
-
G
R
L
G
V
A
D
R
Y
Q
D
--
I
A
L
A
T
R
D
I
-----------------
A
-------------------------------------------------------------------------------------------------------
60
HHSearch
63.59
19%
33
- C- -
-
4H05
-
?
B:
[27-226]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
G
V
Y
R
L
R
G
G-
G
-----
R
----
E
L
F
V
K
--
V
A
A
---
L
---
G
A
G
V
------
G
L
----
L
---------
G
E
A
E
R
L
V
W
L
A
E
---
V
---
G
I
P
V
P
R
V
V
E
G
G
G
-
D
E
---
R
V
A
W
L
V
T
E
A
V
P
G
R
P
A
S
-
A
-
R
W
--------------------
P
R
E
Q
R
L
D
V
A
V
A
L
A
G
L
A
R
S
L
H
-
A
L
D
W
E
R
C
P
F
------------
D
R
S
L
A
V
T
V
P
Q
A
A
R
A
V
A
---
E
-----
G
S
---
V
D
L
E
D
L
D
E
E
R
--
K
-
G
W
S
G
E
R
L
L
A
E
L
E
R
T
R
P
------
A
D
E
D
L
A
V
C
H
G
D
L
C
P
D
N
V
L
L
D
P
R
T
C
---
E
V
T
G
L
-------
I
D
V
-
G
R
V
G
R
A
D
R
H
S
D
--
L
A
L
V
L
R
E
L
-----------------
A
H
------------------------------------------------------------------------------------------------------
59
HHSearch
62.98
19%
28
- C- -
-
4H05
-
?
A:
[27-226]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
G
V
Y
R
L
R
G
G-
G
-----
R
----
E
L
F
V
K
--
V
A
A
---
L
---
G
A
G
V
------
G
L
----
L
---------
G
E
A
E
R
L
V
W
L
A
E
---
V
---
G
I
P
V
P
R
V
V
E
G
G
G
-
D
E
---
R
V
A
W
L
V
T
E
A
V
P
G
R
P
A
S
-
A
-
R
W
--------------------
P
R
E
Q
R
L
D
V
A
V
A
L
A
G
L
A
R
S
L
H
-
A
L
D
W
E
R
C
P
F
------------
D
R
S
L
A
V
T
V
P
Q
A
A
R
A
V
A
---
E
-----
G
S
---
V
D
L
E
D
L
D
E
E
R
--
K
-
G
W
S
G
E
R
L
L
A
E
L
E
R
T
R
P
------
A
D
E
D
L
A
V
C
H
G
D
L
C
P
D
N
V
L
L
D
P
R
T
C
---
E
V
T
G
L
-------
I
D
V
-
G
R
V
G
R
A
D
R
H
S
D
--
L
A
L
V
L
R
E
L
-----------------
A
H
------------------------------------------------------------------------------------------------------
37
SP3
62.25
9%
16
- C2 -
-
1J7L
1
KKA3_ENTFL
A:
[2-264]
-----------------------------------------------------------------------------------------------------------------------------------------------
A
K
M
R
I
S
P
E
L
K
K
L
I
---
E
K
Y
R
C
V
K
D
T
E
G
M
S
P
A
K
V
Y
K
L
V
G
E
--
N
E
N
-
L
Y
---------------------------------
L
K
M
T
----
D
-----
S
----
R
Y
K
-----
G
T
---
T
---
Y
---------
D
V
----
E
---------
R
E
K
D
M
M
L
W
L
E
G
-------
K
L
P
V
P
K
V
L
H
F
E
R
-
H
D
---
G
W
S
N
L
L
M
S
E
A
D
G
V
L
C
S
-
E
-
E
Y
E
---------
D
----------
E
Q
S
P
E
K
I
I
E
L
Y
A
E
C
I
R
L
F
H
-
S
I
D
I
S
D
C
P
Y
-----------
T
N
S
L
D
S
R
L
A
E
L
D
Y
L
L
N
N
D
L
A
D
-----
V
D
C
E
N
W
E
-----
E
D
T
--
P
-
F
K
D
P
R
E
L
Y
D
F
L
K
T
E
K
P
-------
E
E
E
L
V
F
S
H
G
D
L
G
D
S
N
I
F
V
K
D
G
-----
K
V
S
G
F
-------
I
D
L
-
G
R
S
G
R
A
D
K
W
Y
D
--
I
A
F
C
V
R
S
I
-----------------
R
E
-----
D
I
G
E
--
E
--
Q
Y
V
E
L
F
F
-------
D
L
L
G
I
----
K
P
D
-
W
E
K
I
K
Y
Y
I
L
L
-
D
E
L
F
----------------------------------------------
63
HHSearch
60.70
15%
10
- C2 -
-
5IWU
2
?
A:
[32-239]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
F
Q
A
V
F
A
Q
D
NN
G
-----
I
----
D
W
V
L
R
--
L
P
R
---
R
---
E
D
V
M
P
-----
R
T
----
K
---------
V
E
K
Q
A
L
D
L
V
N
K
---
Y
A
I
-
S
F
Q
A
P
N
W
I
I
Y
--------
T
E
E
L
I
A
Y
K
K
L
D
G
V
P
A
G
-
T
-
I
D
H
---------
N
I
GNYIWEID
I
N
N
V
P
E
L
F
H
K
S
L
G
R
V
L
A
E
L
H
-
S
I
P
S
N
K
A
A
A
-----------
L
D
L
V
V
H
T
P
-
E
E
A
R
M
S
M
K
---
Q
-----
R
M
---
D
A
V
R
A
K
F
-
G
V
--
G
-
E
N
L
W
N
R
W
Q
A
W
L
N
D
D
D
----
M
--
W
P
K
K
T
G
L
I
H
G
D
V
H
A
G
H
T
M
I
D
K
D
A
----
N
V
T
G
L
-------
I
D
W
-
T
E
A
K
V
T
D
V
S
H
D
--
F
I
F
N
Y
R
A
F
-------------------------------------------------------------------------------------------------------------------------
55
HHSearch
59.18
18%
-3
- C2 -
-
1L8T
2
KKA3_ENTFL
A:
[27-228]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
A
K
V
Y
K
L
VGE-
N
-----
E
----
N
L
Y
L
K
--
M
T
D
---
S
---
R
YKGTTY---
D
V
----
E
---------
R
E
K
D
M
M
L
W
L
E
G
-------
K
L
P
V
P
K
V
L
H
F
E
R
-
H
D
---
G
W
S
N
L
L
M
S
E
A
D
G
V
L
C
S
-
E
-
E
Y
E
---------
D
----------
E
Q
S
P
E
K
I
I
E
L
Y
A
E
C
I
R
L
F
H
-
S
I
D
I
S
D
C
P
Y
-----------
T
N
S
L
D
-
S
R
L
A
E
L
D
Y
L
L
N
---
N
-----
D
L
A
D
-
V
D
C
E
N
W
E
E
D
T
--
P
-
F
K
D
P
R
E
L
Y
D
F
L
K
T
E
K
-------
P
E
E
E
L
V
F
S
H
G
D
L
G
D
S
N
I
F
V
K
D
G
-----
K
V
S
G
F
-------
I
D
L
-
G
R
S
G
R
A
D
K
W
Y
D
--
I
A
F
C
V
R
S
I
-----------------
R
-------------------------------------------------------------------------------------------------------
64
HHSearch
59.16
15%
8
- C2 -
-
5UXA
-
?
A:
[32-239]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
F
Q
A
V
F
A
Q
D
NN
G
-----
I
----
D
W
V
L
R
--
L
P
R
---
R
---
E
D
V
M
P
-----
R
T
----
K
---------
V
E
K
Q
A
L
D
L
V
N
K
---
Y
A
I
-
S
F
Q
A
P
N
W
I
I
Y
--------
T
E
E
L
I
A
Y
K
K
L
D
G
V
P
A
G
-
T
-
I
D
H
---------
N
I
GNYIWEID
I
N
N
V
P
E
L
F
H
K
S
L
G
R
V
L
A
E
L
H
-
S
I
P
S
N
K
A
A
A
-----------
L
D
L
V
V
H
T
P
-
E
E
A
R
M
S
M
K
---
Q
-----
R
M
---
D
A
V
R
A
K
F
-
G
V
--
G
-
E
N
L
W
N
R
W
Q
A
W
L
N
D
D
D
----
M
--
W
P
K
K
T
G
L
I
H
G
D
V
H
A
G
H
T
M
I
D
K
D
A
----
N
V
T
G
L
-------
I
D
W
-
T
E
A
K
V
T
D
V
S
H
D
--
F
I
F
N
Y
R
A
F
-------------------------------------------------------------------------------------------------------------------------
47
HHSearch
59.12
15%
-4
- C2 -
-
3TDW
1
?
A:
[30-239]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
F
R
N
Y
A
I
L
V
----
N
-----
G
----
D
W
V
F
R
--
F
P
K
---
S
---
Q
Q
G
A
D
-----
E
L
----
N
---------
K
E
I
Q
L
L
P
L
L
V
G
---
C
V
--
K
V
N
I
P
Q
Y
V
Y
I
G
K
R
S
D
---
G
N
P
F
V
G
Y
R
K
V
Q
G
Q
I
L
G
-
E
D
G
M
A
---------
V
L
--------
P
D
D
A
K
D
R
L
A
L
Q
L
A
E
F
M
N
E
L
S
-
A
F
P
V
E
T
A
I
S
-----------
A
G
V
P
V
----
T
N
L
K
N
K
I
L
L
L
S
-----------
E
A
V
E
D
Q
V
F
P
L
--
L
D
E
S
L
R
D
Y
L
T
L
R
F
Q
S
Y
M
T
HPV
Y
--
T
R
Y
T
P
R
L
I
H
G
D
L
S
P
D
H
F
L
T
N
L
N
S
-
R
Q
T
P
L
T
G
I
-------
I
D
F
-
G
D
A
A
I
S
D
P
D
Y
D
--
Y
V
Y
L
L
E
D
C
-----------------
G
-------------------------------------------------------------------------------------------------------
54
HHSearch
59.05
18%
-3
- C2 -
-
3TM0
2
KKA3_ENTFL
A:
[27-228]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
A
K
V
Y
K
L
V
G
E-
N
-----
E
----
N
L
Y
L
K
--
M
T
D
---
S
---
R
YKGTTY---
D
V
----
E
---------
R
E
K
D
M
M
L
W
L
E
G
-------
K
L
P
V
P
K
V
L
H
F
E
R
-
H
D
---
G
W
S
N
L
L
M
S
E
A
D
G
V
L
C
S
-
E
-
E
Y
E
---------
D
----------
E
Q
S
P
E
K
I
I
E
L
Y
A
E
C
I
R
L
F
H
-
S
I
D
I
S
D
C
P
Y
-----------
T
N
S
L
D
-
S
R
L
A
E
L
D
Y
L
L
N
---
N
-----
D
L
A
D
-
V
D
C
E
N
W
E
E
D
T
--
P
-
F
K
D
P
R
E
L
Y
D
F
L
K
T
E
K
-------
P
E
E
E
L
V
F
S
H
G
D
L
G
D
S
N
I
F
V
K
D
G
-----
K
V
S
G
F
-------
I
D
L
-
G
R
S
G
R
A
D
K
W
Y
D
--
I
A
F
C
V
R
S
I
-----------------
R
-------------------------------------------------------------------------------------------------------
66
HHSearch
58.54
14%
-26
- C2 -
-
3ATS
1
Y3168_MYCTU
A:
[53-267]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
----
K
L
V
A
R
--
V
A
P
---
A
---
A
EDVPVFPTY
R
L
----
D
---------
H
Q
F
E
V
I
R
L
V
G
E
---
L
-
T
-
D
V
P
V
P
R
V
R
W
I
E
T
-
T
G
DVL
G
T
P
F
F
L
M
D
Y
V
E
G
V
V
P
P
-
D
-
V
M
P
YTFGDNWFA
D
A
--------
P
A
E
R
Q
R
Q
L
Q
D
A
T
V
A
A
L
A
T
L
H
-
S
I
P
N
A
Q
N
T
------------
F
S
F
L
T
----
D
T
T
L
H
------
R
-----
H
F
N
W
V
R
S
W
Y
D
F
A
V
E
G
I
G
R
-
S
P
L
L
E
R
T
F
E
W
L
Q
S
H
W
P
---
D
D
A
A
A
R
E
P
V
L
L
W
G
D
A
R
V
G
N
V
L
Y
R
D
F
-----
Q
P
V
A
V
-------
L
D
W
-
E
M
V
A
L
G
P
R
E
L
D
--
V
A
W
M
I
F
A
H
-----------------
R
-------------------------------------------------------------------------------------------------------
49
HHSearch
58.22
13%
17
- C2 -
-
5IQI
1
AACA_STAAU
C:
[36-240]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
G
Y
D
S
V
A
Y
L
V
----
N
-----
N
----
E
Y
I
F
K
--
T
K
F
---
S
---
T
NKKK-----
G
F
----
A
---------
K
E
K
A
I
Y
N
F
L
N
T
---
N
L
E
T
N
V
K
I
P
N
I
E
Y
S
Y
I
-
S
D
---
E
L
S
I
L
G
Y
K
E
I
K
G
T
F
L
T
P
E
-
I
Y
S
---------
T
M
--------
S
E
E
E
Q
N
L
L
K
R
D
I
A
S
F
L
R
Q
M
H
-
G
L
D
Y
T
D
I
S
E
-----------
C
T
I
D
N
K
Q
--
N
V
L
E
E
Y
I
L
L
------------
R
E
T
I
Y
N
D
L
T
D
I
--
E
-
K
D
Y
I
E
S
F
M
E
R
L
N
A
T
T
V
------
F
E
G
K
K
C
L
C
H
N
D
F
S
C
N
H
L
L
L
D
G
N
N
----
R
L
T
G
I
-------
I
D
F
-
G
D
S
G
I
I
D
E
Y
C
D
--
F
I
Y
L
L
E
D
S
-----------------
E
-------------------------------------------------------------------------------------------------------