@TOME V3
(Feb 2022)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
3D Alignment Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
3D Alignment Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
PDB Ligands
Affinity Score
Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
Sequence Alignment
Tab of Complexes
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : D1BT79_XYLCX: (2019-01-27 )
MRAELDVTVDLARALLVEQHPDLAHLPLAVAANGWDNVMVRAGSDLVLRLPRRAVAAPLLINERAALPLLEPVLSAAVPGVLVPVPVREGAPSEALGYPWPWNVLRWVDGVRAASTPVESRRAWAPTLGRFLAALHRPIADGVPVPRNPFRGVPLAARAVPPFAHLAAHAQHLLPGADAAAHEAALRSTWAQALRAPAYDGPPVWIHGDPHPANLVVAPGAPAPAAAGHGAHDRLVAVVDFGDVTAGDPASDLGSLWLTFDAEGRTACRRAMSDAGAVRDEATWVRARGWAMAFAGTMLAHPDEHPTMVPIGEHALAALLDDR
Atome Classification :
(21 SA)
.........10........20........30........40..----......50........60........70..-......80........90........100.......110.....-----.------------.120.......130...-----....140.....--..150---.......160......-.170.......180.......190..-..-...200...-------....210.......---220........230.......240.......250.......---260.......270...-....280.......290--.......300..--.....310.......320.---
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MRAE
L
D
V
T
V
D
L
A
R
A
L
L
V
EQHPDLAHL
P
L
A
V
AANGWD
N
V
M
V
RAG----SD
L
V
L
RL
P
R
R
AVAA
P
L
L
INERAA
L
P
L
L
E
P
V
-
L
S
AAVP
G
V
L
V
PVPVREGAPSEALGYPWP
W
N
V
L
R
W
VDGVRAASTP-----V------------ESRRA
W
A
P
T
L
G
R
F
L
A
A
L
-----HRPIADGVPVPR--NPFRG---VPLAARAVP
P
F
A
H
L
A
A
-
H
A
Q
H
LLPGA
D
A
A
A
H
E
A
A
L
R
S
T
W
A
Q
A
L
-RA-PAYDGP
P
V
W
-------IHGDPHPA
N
L
V
VAP---G-APAPAAAGHGAH
D
R
L
V
A
V
V
D
FGDVTAGD
P
A
S
DLG
S
L
W
L
T
---FDAE
G
R
T
A
C
R
R
A
M
S
DA-GAVRDE
A
T
W
V
RARG
W
A
M
--
A
F
A
G
T
MLAHPDE--HP
T
M
VP
I
G
E
H
A
L
A
A
L
LDDR---
2
PsiBlast_PDB
82.91
23%
-64
- C2 -
-
3TDV
1
?
A:
[10-268]
-------------
T
M
I
M
T
Q
F
P
D
I
S
I
Q
S
V
E
S
L
G
E
G
F
R
N
Y
A
I
L
V
N
----
G
D
W
V
F
R
F
P
K
S
Q
Q
G
A
D
E
L
N
K
E
I
Q
L
L
P
L
L
V
G
C
-
V
K
V
N
I
P
Q
Y
V
Y
I
G
K
R
S
D
G
N
P
--
F
V
G
Y
R
K
V
Q
G
Q
I
L
G
E
D
G
M
--
A
V
F
P
-----
D
------------
D
A
K
D
R
L
A
L
Q
L
A
E
F
M
N
E
L
S
A
FP
V
E
T
A
I
S
A
G
V
P
V
T
---
N
L
K
N
K
---
I
L
L
L
S
E
A
V
E
----------
D
Q
V
F
P
L
L
D
E
S
L
R
D
Y
L
-------
T
L
-
R
F
-
Q
S
Y
M
T
H
P
V
Y
T
R
Y
T
P
R
L
I
H
G
D
L
S
P
D
H
F
L
T
N
L
---
N
-
S
R
Q
T
P
L
T
G
---------
I
I
D
F
G
D
A
A
I
S
D
P
--
D
Y
D
Y
V
Y
L
L
---
E
D
C
-
G
E
L
F
T
R
Q
V
M
A
Y
R
-
G
E
V
-
D
L
D
T
H
I
R
K
V
S
L
F
V
--
T
F
----------------------------------
1
PsiBlast_PDB
82.62
23%
-61
- C2 -
-
3TDW
1
?
A:
[10-268]
-------------
T
M
I
M
T
Q
F
P
D
I
S
I
Q
S
V
E
S
L
G
E
G
F
R
N
Y
A
I
L
V
N
----
G
D
W
V
F
R
F
P
K
S
Q
Q
G
A
D
E
L
N
K
E
I
Q
L
L
P
L
L
V
G
C
-
V
K
V
N
I
P
Q
Y
V
Y
I
G
K
R
S
D
G
N
P
--
F
V
G
Y
R
K
V
Q
G
Q
I
L
G
E
D
G
M
--
A
V
L
P
-----
D
------------
D
A
K
D
R
L
A
L
Q
L
A
E
F
M
N
E
L
S
A
FP
V
E
T
A
I
S
A
G
V
P
V
T
---
N
L
K
N
K
---
I
L
L
L
S
E
A
V
E
----------
D
Q
V
F
P
L
L
D
E
S
L
R
D
Y
L
-------
T
L
-
R
F
-
Q
S
Y
M
T
H
P
V
Y
TRYT
P
R
L
I
H
G
D
L
S
P
D
H
F
L
T
N
L
---
N
-
S
R
Q
T
P
L
T
G
---------
I
I
D
F
G
D
A
A
I
S
D
P
--
D
Y
D
Y
V
Y
L
L
---
E
D
C
-
G
E
L
F
T
R
Q
V
M
A
Y
R
-
G
E
V
-
D
L
D
T
H
I
R
K
V
S
L
F
V
--
T
F
----------------------------------
18
PsiBlast_PDB
78.56
19%
-65
- C2 -
-
4DFB
1
?
A:
[26-256]
-------
T
F
D
Q
V
E
K
A
I
E
Q
L
Y
P
D
F
T
I
N
T
I
E
I
S
G
E
G
N
D
C
I
A
Y
E
I
N
----
R
D
F
I
F
K
F
P
K
H
S
R
G
S
T
N
L
F
N
E
V
N
I
L
K
R
I
H
N
K
-
L
P
L
P
I
P
E
V
V
F
T
-----
G
M
P
S
E
T
--
Y
Q
M
S
F
A
G
F
T
K
I
K
G
V
P
L
T
P
L
L
-----
L
N
N
LP
K
-------
Q
S
Q
N
Q
A
A
K
D
L
A
R
F
L
S
E
L
-----
H
S
I
N
I
S
G
---------
F
K
S
NLV
L
D
F
R
E
K
I
N
E
D
N
K
K
I
K
K
-
L
L
S
R
E
L
K
G
P
Q
M
K
K
V
D
D
F
Y
R
D
I
L
E
N
E
I
-
Y
F
-
K
Y
Y
---
P
C
L
-------
I
H
N
D
F
S
S
D
H
I
L
F
D
T
---------------
E
K
N
T
I
C
G
I
I
D
F
G
D
A
A
I
S
D
P
D
N
D
F
I
S
L
------------------------------------------------------------------------------
15
PsiBlast_PDB
78.24
19%
-67
- C2 -
-
3SG8
1
?
A:
[5-233]
-------
T
F
D
Q
V
E
K
A
I
E
Q
L
Y
P
D
F
T
I
N
T
I
E
I
S
G
E
G
N
D
C
I
A
Y
E
I
N
----
R
D
F
I
F
K
F
P
K
H
S
R
G
S
T
N
L
F
N
E
V
N
I
L
K
R
I
H
N
K
-
L
P
L
P
I
P
E
V
V
F
T
-----
G
M
P
S
E
T
--
Y
Q
M
S
F
A
G
F
T
K
I
K
G
V
P
L
T
P
L
L
-----
L
N
N
LP
K
-------
Q
S
Q
N
Q
A
A
K
D
L
A
R
F
L
S
E
L
-----
H
S
I
N
I
S
G
---------
F
K
S
NLV
L
D
F
R
E
K
I
N
E
D
N
K
K
I
K
K
-
L
L
S
R
E
L
K
G
P
Q
M
K
K
V
D
D
F
Y
R
D
I
L
E
N
E
I
-
Y
F
-
K
Y
Y
---
P
C
L
-------
I
H
N
D
F
S
S
D
H
I
L
F
D
T
---------------
E
K
N
T
I
C
G
I
I
D
F
G
D
A
A
I
S
D
P
D
N
D
F
I
S
L
------------------------------------------------------------------------------
66
HHSearch
78.22
18%
-39
- C- -
-
3N4U
-
?
A:
[3-298]
-----
T
Y
T
F
D
Q
V
E
K
A
I
E
Q
L
Y
P
D
F
T
I
N
T
I
E
I
S
G
E
G
N
D
C
I
A
Y
E
I
N
----
R
D
F
I
F
K
F
P
K
H
S
R
G
S
T
N
L
F
N
E
V
N
I
L
K
R
I
H
N
K
-
L
P
-----
L
P
I
P
E
V
V
F
T
G
M
P
S
E
--
T
Y
Q
M
S
F
A
G
F
T
K
I
K
G
V
P
L
T
P
L
L
-----
L
N
N
LP
K
-------
Q
S
Q
N
Q
A
A
K
D
L
A
R
F
L
S
E
L
-----
H
S
I
N
I
S
G
F
K
S
N
L
--
V
L
D
F
R
---
E
K
I
N
E
D
N
K
K
I
K
K
L
L
S
R
-----
E
L
K
G
P
Q
M
----
K
K
V
D
D
F
Y
R
D
I
L
-
E
N
E
I
Y
F
K
Y
Y
P
C
L
-------
I
H
N
D
F
S
S
D
H
I
L
F
D
T
---
E
K
N
------------
T
I
C
G
I
I
D
F
G
D
A
A
I
S
D
P
D
N
D
F
I
S
L
M
E
D
DEE
Y
G
M
E
F
V
S
K
I
L
N
H
Y
K
H
K
-
D
---
I
P
T
V
L
E
K
Y
R
M
K
E
K
--
Y
W
S
F
E
K
I
I
Y
G
K
E
Y
G
Y
M
D
W
Y
E
E
G
L
N
E
I
R
S
I
-------
7
PsiBlast_PDB
78.16
19%
-59
- C2 -
-
4DTA
1
?
A:
[5-233]
-------
T
F
D
Q
V
E
K
A
I
E
Q
L
Y
P
D
F
T
I
N
T
I
E
I
S
G
E
G
N
D
C
I
A
Y
E
I
N
----
R
D
F
I
F
K
F
P
K
H
S
R
G
S
T
N
L
F
N
E
V
N
I
L
K
R
I
H
N
K
-
L
P
L
P
I
P
E
V
V
F
T
-----
G
M
P
S
E
T
--
Y
Q
M
S
F
A
G
M
T
K
I
K
G
V
P
L
T
P
L
L
-----
L
N
N
LP
K
-------
Q
S
Q
N
Q
A
A
K
D
L
A
R
F
L
S
E
L
-----
H
S
I
N
I
S
G
---------
F
K
S
NLV
L
D
F
R
E
K
I
N
E
D
N
K
K
I
K
K
-
L
L
S
R
E
L
K
G
P
Q
M
K
K
V
D
D
F
Y
R
D
I
L
E
N
E
I
-
Y
F
-
K
Y
Y
---
P
C
L
-------
I
H
N
D
F
S
S
D
H
I
L
F
D
T
---------------
E
K
N
T
I
C
G
I
I
D
F
G
D
A
A
I
S
D
P
D
N
D
F
I
S
L
------------------------------------------------------------------------------
10
PsiBlast_PDB
78.13
19%
-67
- C2 -
-
3SG9
1
?
A:
[5-233]
-------
T
F
D
Q
V
E
K
A
I
E
Q
L
Y
P
D
F
T
I
N
T
I
E
I
S
G
E
G
N
D
C
I
A
Y
E
I
N
----
R
D
F
I
F
K
F
P
K
H
S
R
G
S
T
N
L
F
N
E
V
N
I
L
K
R
I
H
N
K
-
L
P
L
P
I
P
E
V
V
F
T
-----
G
M
P
S
E
T
--
Y
Q
M
S
F
A
G
F
T
K
I
K
G
V
P
L
T
P
L
L
-----
L
N
N
LP
K
-------
Q
S
Q
N
Q
A
A
K
D
L
A
R
F
L
S
E
L
-----
H
S
I
N
I
S
G
---------
F
K
S
NLV
L
D
F
R
E
K
I
N
E
D
N
K
K
I
K
K
-
L
L
S
R
E
L
K
G
P
Q
M
K
K
V
D
D
F
Y
R
D
I
L
E
N
E
I
-
Y
F
-
K
Y
Y
---
P
C
L
-------
I
H
N
D
F
S
S
D
H
I
L
F
D
T
---------------
E
K
N
T
I
C
G
I
I
D
F
G
D
A
A
I
S
D
P
D
N
D
F
I
S
L
------------------------------------------------------------------------------
14
PsiBlast_PDB
78.05
19%
-62
- C- -
-
3N4U
-
?
A:
[5-233]
-------
T
F
D
Q
V
E
K
A
I
E
Q
L
Y
P
D
F
T
I
N
T
I
E
I
S
G
E
G
N
D
C
I
A
Y
E
I
N
----
R
D
F
I
F
K
F
P
K
H
S
R
G
S
T
N
L
F
N
E
V
N
I
L
K
R
I
H
N
K
-
L
P
L
P
I
P
E
V
V
F
T
-----
G
M
P
S
E
T
--
Y
Q
M
S
F
A
G
F
T
K
I
K
G
V
P
L
T
P
L
L
-----
L
N
N
LP
K
-------
Q
S
Q
N
Q
A
A
K
D
L
A
R
F
L
S
E
L
-----
H
S
I
N
I
S
G
---------
F
K
S
NLV
L
D
F
R
E
K
I
N
E
D
N
K
K
I
K
K
-
L
L
S
R
E
L
K
G
P
Q
M
K
K
V
D
D
F
Y
R
D
I
L
E
N
E
I
-
Y
F
-
K
Y
Y
---
P
C
L
-------
I
H
N
D
F
S
S
D
H
I
L
F
D
T
---------------
E
K
N
T
I
C
G
I
I
D
F
G
D
A
A
I
S
D
P
D
N
D
F
I
S
L
------------------------------------------------------------------------------
6
PsiBlast_PDB
77.81
19%
-63
- C2 -
-
5C4L
-
?
A:
[25-253]
-------
T
F
D
Q
V
E
K
A
I
E
Q
L
Y
P
D
F
T
I
N
T
I
Q
I
S
G
K
G
N
D
C
I
A
Y
E
I
N
----
R
D
F
I
F
K
F
P
K
H
S
R
G
S
T
N
L
F
N
E
V
N
I
L
K
R
I
H
N
K
-
L
P
L
P
I
P
E
V
V
F
T
-----
G
M
P
S
E
T
--
Y
Q
M
S
F
A
G
F
T
K
I
K
G
V
P
L
T
P
L
L
-----
L
N
N
LP
K
-------
Q
S
Q
N
Q
A
A
K
D
L
A
R
F
L
S
E
L
-----
H
S
I
N
I
S
G
---------
F
K
S
NLV
L
D
F
R
E
K
I
N
E
D
N
K
K
I
K
K
-
L
L
S
R
E
L
K
G
P
Q
M
K
K
V
D
D
F
Y
R
D
I
L
E
N
E
I
-
Y
F
-
K
Y
Y
---
P
C
L
-------
I
H
N
D
F
S
S
D
H
I
L
F
D
T
---------------
E
K
N
T
I
C
G
I
I
D
F
G
D
A
A
I
S
D
P
D
N
D
F
I
S
L
------------------------------------------------------------------------------
11
PsiBlast_PDB
77.32
19%
-62
- C2 -
-
4DT8
1
?
A:
[5-233]
-------
T
F
D
Q
V
E
K
A
I
E
Q
L
Y
P
D
F
T
I
N
T
I
E
I
S
G
E
G
N
D
C
I
A
Y
E
I
N
----
R
D
F
I
F
K
F
P
K
H
S
R
G
S
T
N
L
F
N
E
V
N
I
L
K
R
I
H
N
K
-
L
P
L
P
I
P
E
V
V
F
T
-----
G
M
P
S
E
T
--
Y
Q
M
S
F
A
G
F
T
K
I
K
G
V
P
L
T
P
L
L
-----
L
N
N
LP
K
-------
Q
S
Q
N
Q
A
A
K
D
L
A
R
F
L
S
E
L
-----
H
S
I
N
I
S
G
---------
F
K
S
NLV
L
D
F
R
E
K
I
N
E
D
N
K
K
I
K
K
-
L
L
S
R
E
L
K
G
P
Q
M
K
K
V
D
D
F
Y
R
D
I
L
E
N
E
I
-
Y
F
-
K
Y
Y
---
P
C
L
-------
I
H
N
D
F
S
S
D
H
I
L
F
D
T
---------------
E
K
N
T
I
C
G
I
I
D
F
G
D
A
A
I
S
D
P
D
N
D
F
I
S
L
------------------------------------------------------------------------------
19
PsiBlast_PDB
76.87
19%
-62
- C2 -
-
4DFU
3
?
A:
[26-254]
-------
T
F
D
Q
V
E
K
A
I
E
Q
L
Y
P
D
F
T
I
N
T
I
E
I
S
G
E
G
N
D
C
I
A
Y
E
I
N
----
R
D
F
I
F
K
F
P
K
H
S
R
G
S
T
N
L
F
N
E
V
N
I
L
K
R
I
H
N
K
-
L
P
L
P
I
P
E
V
V
F
T
-----
G
M
P
S
E
T
--
Y
Q
M
S
F
A
G
F
T
K
I
K
G
V
P
L
T
P
L
L
-----
L
N
N
LP
K
-------
Q
S
Q
N
Q
A
A
K
D
L
A
R
F
L
S
E
L
-----
H
S
I
N
I
S
G
---------
F
K
S
NLV
L
D
F
R
E
K
I
N
E
D
N
K
K
I
K
K
-
L
L
S
R
E
L
K
G
P
Q
M
K
K
V
D
D
F
Y
R
D
I
L
E
N
E
I
-
Y
F
-
K
Y
Y
---
P
C
L
-------
I
H
N
D
F
S
S
D
H
I
L
F
D
T
---------------
E
K
N
T
I
C
G
I
I
D
F
G
D
A
A
I
S
D
P
D
N
D
F
I
S
L
------------------------------------------------------------------------------
17
PsiBlast_PDB
75.91
19%
-61
- C2 -
-
4DE4
1
?
A:
[26-254]
-------
T
F
D
Q
V
E
K
A
I
E
Q
L
Y
P
D
F
T
I
N
T
I
E
I
S
G
E
G
N
D
C
I
A
Y
E
I
N
----
R
D
F
I
F
K
F
P
K
H
S
R
G
S
T
N
L
F
N
E
V
N
I
L
K
R
I
H
N
K
-
L
P
L
P
I
P
E
V
V
F
T
-----
G
M
P
S
E
T
--
Y
Q
M
S
F
A
G
F
T
K
I
K
G
V
P
L
T
P
L
L
-----
L
N
N
LP
K
-------
Q
S
Q
N
Q
A
A
K
D
L
A
R
F
L
S
E
L
-----
H
S
I
N
I
S
G
---------
F
K
S
NLV
L
D
F
R
E
K
I
N
E
D
N
K
K
I
K
K
-
L
L
S
R
E
L
K
G
P
Q
M
K
K
V
D
D
F
Y
R
D
I
L
E
N
E
I
-
Y
F
-
K
Y
Y
---
P
C
L
-------
I
H
N
D
F
S
S
D
H
I
L
F
D
T
---------------
E
K
N
T
I
C
G
I
I
D
F
G
D
A
A
I
S
D
P
D
N
D
F
I
S
L
------------------------------------------------------------------------------
4
PsiBlast_PDB
75.59
19%
-66
- C2 -
-
4N57
1
?
A:
[25-253]
-------
T
F
D
Q
V
E
K
A
I
E
Q
L
Y
P
D
F
T
I
N
T
I
Q
I
S
G
K
G
N
D
C
I
A
Y
E
I
N
----
R
D
F
I
F
K
F
P
K
H
S
R
G
S
T
N
L
F
N
E
V
N
I
L
K
R
I
H
N
K
-
L
P
L
P
I
P
E
V
V
F
T
-----
G
M
P
S
E
T
--
Y
Q
M
S
F
A
G
F
T
K
I
K
G
V
P
L
T
P
L
L
-----
L
N
N
LP
K
-------
Q
S
Q
N
Q
A
A
K
D
L
A
R
F
L
S
E
L
-----
H
S
I
N
I
S
G
---------
F
K
S
NLV
L
D
F
R
E
K
I
N
E
D
N
K
K
I
K
K
-
L
L
S
R
E
L
K
G
P
Q
M
K
K
V
D
D
F
Y
R
D
I
L
E
N
E
I
-
Y
F
-
K
Y
Y
---
P
C
L
-------
I
H
N
D
F
S
S
D
H
I
L
F
D
T
---------------
E
K
N
T
I
C
G
I
I
D
F
G
D
A
A
I
S
D
P
D
N
D
F
I
S
L
------------------------------------------------------------------------------
72
HHSearch
75.56
19%
-29
- C2 -
-
5IWU
2
?
A:
[2-299]
-----
S
K
D
I
K
Q
V
I
E
I
A
K
K
H
N
L
F
L
K
E
E
T
I
Q
F
N
E
S
G
L
D
F
Q
A
V
F
A
Q
D
NNG
I
D
W
V
L
R
L
P
R
R
E
D
V
M
P
R
T
K
V
E
K
Q
A
L
D
L
V
N
K
Y
A
I
S
-----
F
Q
A
P
N
W
I
I
Y
T
---------
E
E
L
I
A
Y
K
K
L
D
G
V
P
A
G
T
I
D
-----
H
NIGNYIWEIDIN
N
V
P
E
L
F
H
K
S
L
G
R
V
L
A
E
L
-----
H
S
I
P
S
N
K
A
A
A
L
D
L
-
V
V
H
T
P
---
E
E
A
---
R
M
S
M
K
Q
R
M
D
A
-
V
R
A
-
K
F
G
--
V
G
----
E
N
L
W
N
R
W
Q
A
W
L
-
N
D
D
D
M
W
P
K
K
T
G
L
-------
I
H
G
D
V
H
A
G
H
T
M
I
D
K
---
D
-
A
------------
N
V
T
G
L
I
D
W
T
E
A
K
V
T
D
V
S
H
D
F
I
F
N
Y
R
A
---
F
G
E
E
G
L
E
A
L
I
L
A
Y
K
E
I
-
G
G
Y
Y
W
P
K
M
K
E
H
I
I
E
L
N
A
--
A
Y
P
V
S
I
A
E
F
A
L
V
S
G
I
E
E
Y
E
Q
M
A
K
E
A
L
E
V
--------
5
PsiBlast_PDB
75.56
19%
-67
- C2 -
-
5C4K
1
?
A:
[25-253]
-------
T
F
D
Q
V
E
K
A
I
E
Q
L
Y
P
D
F
T
I
N
T
I
Q
I
S
G
K
G
N
D
C
I
A
Y
E
I
N
----
R
D
F
I
F
K
F
P
K
H
S
R
G
S
T
N
L
F
N
E
V
N
I
L
K
R
I
H
N
K
-
L
P
L
P
I
P
E
V
V
F
T
-----
G
M
P
S
E
T
--
Y
Q
M
S
F
A
G
F
T
K
I
K
G
V
P
L
T
P
L
L
-----
L
N
N
LP
K
-------
Q
S
Q
N
Q
A
A
K
D
L
A
R
F
L
S
E
L
-----
H
S
I
N
I
S
G
---------
F
K
S
NLV
L
D
F
R
E
K
I
N
E
D
N
K
K
I
K
K
-
L
L
S
R
E
L
K
G
P
Q
M
K
K
V
D
D
F
Y
R
D
I
L
E
N
E
I
-
Y
F
-
K
Y
Y
---
P
C
L
-------
I
H
N
D
F
S
S
D
H
I
L
F
D
T
---------------
E
K
N
T
I
C
G
I
I
D
F
G
D
A
A
I
S
D
P
D
N
D
F
I
S
L
------------------------------------------------------------------------------
8
PsiBlast_PDB
75.50
19%
-65
- C2 -
-
6CD7
-
?
A:
[6-234]
-------
T
F
D
Q
V
E
K
A
I
E
Q
L
Y
P
D
F
T
I
N
T
I
E
I
S
G
E
G
N
D
C
I
A
Y
E
I
N
----
R
D
F
I
F
K
F
P
K
H
S
R
G
S
T
N
L
F
N
E
V
N
I
L
K
R
I
H
N
K
-
L
P
L
P
I
P
E
V
V
F
T
-----
G
M
P
S
E
T
--
Y
Q
M
S
F
A
G
F
T
K
I
K
G
V
P
L
T
P
L
L
-----
L
N
N
LP
K
-------
Q
S
Q
N
Q
A
A
K
D
L
A
R
F
L
S
E
L
-----
H
S
I
N
I
S
G
---------
F
K
S
NLV
L
D
F
R
E
K
I
N
E
D
N
K
K
I
K
K
-
L
L
S
R
E
L
K
G
P
Q
M
K
K
V
D
D
F
Y
R
D
I
L
E
N
E
I
-
Y
F
-
K
Y
Y
---
P
C
L
-------
I
H
N
D
F
S
S
D
H
I
L
F
D
T
---------------
E
K
N
T
I
C
G
I
I
D
F
G
D
A
A
I
S
D
P
D
N
D
F
I
S
L
------------------------------------------------------------------------------
12
PsiBlast_PDB
75.41
19%
-60
- C2 -
-
4DT9
1
?
A:
[5-233]
-------
T
F
D
Q
V
E
K
A
I
E
Q
L
Y
P
D
F
T
I
N
T
I
E
I
S
G
E
G
N
D
C
I
A
Y
E
I
N
----
R
D
F
I
F
K
F
P
K
H
S
R
G
S
T
N
L
F
N
E
V
N
I
L
K
R
I
H
N
K
-
L
P
L
P
I
P
E
V
V
F
T
-----
G
M
P
S
E
T
--
Y
Q
M
S
F
A
G
F
T
K
I
K
G
V
P
L
T
P
L
L
-----
L
N
N
LP
K
-------
Q
S
Q
N
Q
A
A
K
D
L
A
R
F
L
S
E
L
-----
H
S
I
N
I
S
G
---------
F
K
S
NLV
L
D
F
R
E
K
I
N
E
D
N
K
K
I
K
K
-
L
L
S
R
E
L
K
G
P
Q
M
K
K
V
D
D
F
Y
R
D
I
L
E
N
E
I
-
Y
F
-
K
Y
Y
---
P
C
L
-------
I
H
N
D
F
S
S
D
H
I
L
F
D
T
---------------
E
K
N
T
I
C
G
I
I
D
F
G
D
A
A
I
S
D
P
D
N
D
F
I
S
L
------------------------------------------------------------------------------
16
PsiBlast_PDB
75.18
19%
-111
- C- -
-
4DBX
-
?
A:
[5-233]
-------
T
F
D
Q
V
E
K
A
I
E
Q
L
Y
P
D
F
T
I
N
T
I
E
I
S
G
E
G
N
D
C
I
A
Y
E
I
N
----
R
D
F
I
F
K
F
P
K
H
S
R
G
S
T
N
L
F
N
E
V
N
I
L
K
R
I
H
N
K
-
L
P
L
P
I
P
E
V
V
F
T
-----
G
M
P
S
E
T
--
Y
Q
M
S
F
A
G
F
T
K
I
K
G
V
P
L
T
P
L
L
-----
L
N
N
LP
K
-------
Q
S
Q
N
Q
A
A
K
D
L
A
R
F
L
S
E
L
-----
H
S
I
N
I
S
G
---------
F
K
S
NLV
L
D
F
R
E
K
I
N
E
D
N
K
K
I
K
K
-
L
L
S
R
E
L
K
G
P
Q
M
K
K
V
D
D
F
Y
R
D
I
L
E
N
E
I
-
Y
F
-
K
Y
Y
---
P
C
L
-------
I
H
N
D
F
S
S
D
H
I
L
F
D
T
---------------
E
K
N
T
I
C
G
I
I
D
F
G
D
A
A
I
S
D
P
D
N
D
F
I
S
L
------------------------------------------------------------------------------
20
PsiBlast_PDB
75.04
19%
-62
- C2 -
-
4DTB
1
?
A:
[5-233]
-------
T
F
D
Q
V
E
K
A
I
E
Q
L
Y
P
D
F
T
I
N
T
I
E
I
S
G
E
G
N
D
C
I
A
Y
E
I
N
----
R
D
F
I
F
K
F
P
K
H
S
R
G
S
T
N
L
F
N
E
V
N
I
L
K
R
I
H
N
K
-
L
P
L
P
I
P
E
V
V
F
T
-----
G
M
P
S
E
T
--
Y
Q
M
S
F
A
G
Y
T
K
I
K
G
V
P
L
T
P
L
L
-----
L
N
N
LP
K
-------
Q
S
Q
N
Q
A
A
K
D
L
A
R
F
L
S
E
L
-----
H
S
I
N
I
S
G
---------
F
K
S
NLV
L
D
F
R
E
K
I
N
E
D
N
K
K
I
K
K
-
L
L
S
R
E
L
K
G
P
Q
M
K
K
V
D
D
F
Y
R
D
I
L
E
N
E
I
-
Y
F
-
K
Y
Y
---
P
C
L
-------
I
H
N
D
F
S
S
D
H
I
L
F
D
T
---------------
E
K
N
T
I
C
G
I
I
D
F
G
D
A
A
I
S
D
P
D
N
D
F
I
S
L
------------------------------------------------------------------------------
65
HHSearch
74.54
18%
-46
- C2 -
-
3TDW
1
?
A:
[4-298]
-------
N
K
L
H
Y
T
T
M
I
M
T
Q
F
P
D
I
S
I
Q
S
V
E
S
L
G
E
G
F
R
N
Y
A
I
L
V
N
----
G
D
W
V
F
R
F
P
K
S
Q
Q
G
A
D
E
L
N
K
E
I
Q
L
L
P
L
L
V
G
C
-
V
K
-----
V
N
I
P
Q
Y
V
Y
I
G
K
R
----
S
D
G
N
P
F
V
G
Y
R
K
V
Q
G
Q
I
L
G
E
D
G
M
A
V
LP
D
------------
D
A
K
D
R
L
A
L
Q
L
A
E
F
M
N
E
L
-----
S
A
F
P
V
E
T
A
I
S
A
G
--
V
--
P
V
---
T
N
L
K
N
K
I
L
L
L
S
E
A
V
E
D
Q
V
F
P
-
L
L
D
E
S
L
R
----
D
Y
L
T
L
R
F
Q
S
Y
M
-
T
H
P
V
Y
T
R
Y
T
P
R
L
-------
I
H
G
D
L
S
P
D
H
F
L
T
N
L
NSR
Q
-
T
------------
P
L
T
G
I
I
D
F
G
D
A
A
I
S
D
P
D
Y
D
Y
V
Y
L
L
E
D
---
C
G
E
L
F
-
T
R
Q
V
M
A
Y
R
G
E
-
V
D
--
L
D
T
H
I
R
K
V
S
L
F
V
T
--
F
D
Q
V
S
Y
L
L
E
G
L
R
A
R
D
Q
D
W
I
S
E
G
L
E
L
L
E
E
D
K
A
-----
49
Fugue
70.37
16%
-24
- C2 -
-
3HAM
3
?
A:
[1-299]
-------
M
V
N
L
D
A
E
I
Y
E
H
L
N
K
Q
I
K
I
N
E
L
R
Y
L
S
S
G
D
D
S
D
T
F
L
C
N
----
E
Q
Y
V
V
K
V
P
K
R
D
S
V
R
I
S
Q
K
R
E
F
E
L
Y
R
F
L
E
N
-------
C
K
L
S
Y
Q
I
P
-------
A
V
V
Y
Q
S
D
R
F
N
I
M
K
Y
I
K
G
E
R
I
T
Y
E
Q
-----
Y
H
K
LS
E
-------
K
E
K
D
A
L
A
Y
D
E
A
T
F
L
K
E
L
-----
H
S
I
E
I
D
C
S
V
S
L
F
SD
A
L
V
N
K
---
K
D
K
F
L
Q
D
K
K
L
L
I
S
I
L
E
-
K
-----
E
Q
L
L
T
D
E
M
L
E
H
I
E
T
I
Y
E
N
I
L
N
N
A
-
V
L
F
K
Y
T
P
C
L
-------
V
H
N
D
F
S
A
N
N
M
I
F
R
N
---
N
--------------
R
L
F
G
V
I
D
F
G
D
F
N
V
G
D
P
D
N
D
F
L
C
L
L
D
C
---
S
T
D
D
F
G
K
E
F
G
R
K
V
L
K
Y
Y
Q
H
K
A
P
E
V
A
E
R
K
A
E
L
N
D
V
Y
W
S
I
D
Q
I
I
Y
G
Y
E
R
K
--
D
R
E
M
L
I
K
G
V
S
E
L
L
Q
T
Q
A
E
M
FIF