@TOME V3
(Feb 2022)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
3D Alignment Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
3D Alignment Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
PDB Ligands
Affinity Score
Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
Sequence Alignment
Tab of Complexes
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : I0V2R5_9PSEU: (2019-01-29 )
MATLRDGRWIERRPRRPAVTAQLRREASFLPWLAPALPLRVPVPRILVDQPGHEFVSTHELVPGEPLCAFTSANGRRLGRFLRALHSRSSDDAVRHGLLPASGAAEDLANDVNLFRRTVLPLVPAGWRPDAQAVLDRVGTFPFDTVVHGDLGPEHVLTCDDVITGVIDFGDARCGDAAMDFSWVLHGTPSVFGEAAAEEYGVTPAVRERARVWRRLSPWYDVTRGLGTGDADMVRDGLDGLVNRLRKP
Atome Classification :
(20 SA)
........-.10........20........30........40.....----...50.----...-....60.......--.-----70------------....-------.....80-------------------.........90........--100.......110.......----120.......130.......-140---..-..---.-----....150......-.160--..----.......170.......180.......----190..---.....200-----.-....--..210......--.220.......230.......240......
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MATLRDGR-
W
I
ERRPRRP
A
V
T
A
Q
L
R
R
E
ASFLPWLAPALPLRVPVP
R
I
----
L
VDQPG----H
E
F
-
V
S
THELVPGEP
L
C
--
A
-----F-------------TSA
N
-------
G
R
R
L
G
R
--------------------
F
L
R
A
L
HSRSS
D
D
A
V
R
HGLL--PASG
A
A
E
D
L
A
N
D
V
N
L
F
R
R
T
V----LPLVPAGWRP
D
A
Q
A
V
L
D
R
VG-T-----FP-FD---
T
-----
V
VHGDLGPE
H
V
L
T
-
C
D
----
D
V
----
I
T
G
V
I
DFGDARCGDAAM
D
F
S
W
V
LHGT
P
----
S
V
F
G
E
---
A
A
A
E
EYGV-----
T
-
P
A
V
R
--
E
R
A
R
V
W
R
RLS
P
--
W
Y
D
V
T
RGLGTG
D
A
D
M
V
R
D
G
L
D
G
L
V
N
R
LRKP
8
PsiBlast_PDB
75.70
22%
-23
- C2 -
-
3TDW
1
?
A:
[35-293]
-
A
I
L
V
N
G
D
-
W
V
F
R
F
P
K
S
Q
Q
G
A
D
E
L
N
K
E
I
Q
L
L
P
L
L
V
G
C
V
K
V
N
I
P
-------------------
Q
Y
-
V
Y
I
G
K
R
S
D
G
N
P
F
V
--
G
-----
Y
-------------
R
K
V
Q
-------
G
Q
I
L
G
E
D
G
M
A
V
LP
D
D
A
K
D
R
L
A
L
Q
L
A
E
F
M
N
E
L
S
A
F
P
V
E
T
A
I
S
A
G
V
---
P
V
T
N
L
K
N
K
I
L
L
L
S
E
A
V
E
D
Q
V
----
F
P
L
L
D
E
S
L
R
D
Y
L
T
L
R
F
Q
S
Y
M
-
T
-----
H
P
-
V
Y
---
T
RYT
P
R
L
I
H
G
D
L
S
P
D
H
F
L
T
-
N
L
----
N
S
RQTP
L
T
G
I
I
D
F
G
D
A
A
I
S
D
P
D
Y
D
Y
V
Y
L
L
E
D
C
G
----
E
L
F
T
R
Q
V
M
A
Y
R
G
E
V
D
L
-----
D
-
T
H
I
R
---
K
V
S
L
F
V
T
F
D
Q
--
V
S
Y
L
L
E
G
L
R
A
R
D
Q
D
W
I
S
E
G
L
E
L
L
-------
144
HHSearch
74.41
26%
-24
- C2 -
-
5IGH
-
?
A:
[46-299]
-----
G
R
R
-
W
V
L
R
I
P
R
R
A
E
V
S
A
K
V
E
P
E
A
R
V
L
A
M
L
K
N
R
L
P
F
A
V
P
D
W
R
V
----
A
N
A
E
L
V
A
Y
P
M
L
E
D
-
S
T
A
M
V
I
Q
P
G
S
S
T
P
--
D
W
V
V
P
Q
D
-------------
S
E
V
F
-------
A
E
S
F
A
T
--------------------
A
L
A
A
L
H
A
V
P
I
S
A
A
V
D
A
G
M
L
I
R
T
P
T
Q
A
R
Q
K
V
A
D
D
V
D
R
V
R
R
E
F
----
V
--
V
N
D
K
R
L
H
R
W
Q
R
W
L
D
D
D
S
-
S
W----
P
D
-
F
S
---
V
-----
V
V
H
G
D
L
Y
V
G
H
V
L
I
-
D
N
T---
E
R
----
V
S
G
M
I
D
W
S
E
A
R
V
D
D
P
A
I
D
M
A
A
H
L
M
V
F
G
----
E
E
G
L
A
---
K
L
L
L
T
Y
E
A
A
G
G
R
V
W
-
P
R
L
A
--
H
H
I
A
E
R
L
A
F
G
A
--
V
T
Y
A
L
F
A
L
D
S
G
N
E
E
Y
L
A
A
A
K
A
Q
L
A
A
-----
4
PsiBlast_PDB
74.00
32%
1
- C2 -
-
5IGR
3
?
A:
[40-263]
I
A
T
V
D
D
G
R
R
W
V
L
R
I
P
R
R
A
E
V
S
A
K
V
E
P
E
A
R
V
L
A
M
L
K
N
R
L
P
F
A
V
P
D
W
R
V
ANAE
L
V
A
Y
P
M
----
L
E
D
-
S
T
A
M
V
I
Q
P
G
S
S
T
P
--
D
-----
W
VVPQD--------
S
E
V
F
-------
A
E
S
F
A
T
--------------------
A
L
A
A
L
H
A
V
P
I
S
A
A
V
D
A
G
M
L
I
R
T
P
T
Q
A
R
Q
K
V
A
D
D
V
D
R
V
R
R
E
F
------
V
V
N
D
K
R
L
H
R
W
Q
R
W
L
D
D
D
S
-
S
-----
W
P
D
F
S
---
V
-----
V
V
H
G
D
L
Y
V
G
H
V
L
I
-
D
N
T---
E
R
----
V
S
G
M
I
D
W
S
E
A
R
V
D
D
P
A
I
D
M
A
A
H
L
--------
M
V
F
G
E
---
E
G
L
A
K
L
L
L
-----
T
-
Y
E
A
---
A
G
G
R
V
W
P
R
L
A
---------------------------------
143
HHSearch
73.66
26%
-18
- C2 -
-
5IGI
3
?
A:
[46-299]
-----
G
R
R
-
W
V
L
R
I
P
R
R
A
E
V
S
A
K
V
E
P
E
A
R
V
L
A
M
L
K
N
R
L
P
F
A
V
P
D
W
R
V
----
A
N
A
E
L
V
A
Y
PM
L
E
D
-
S
T
A
-
V
I
Q
P
G
S
S
T
P
--
D
WVVPQ
D
-------------
S
E
V
F
-------
A
E
S
F
A
T
--------------------
A
L
A
A
L
H
A
V
P
I
S
A
A
V
D
A
G
M
L
IR
T
P
T
Q
A
R
Q
K
V
A
D
D
V
D
R
V
R
R
E
F
----
V
--
V
N
D
K
R
L
H
R
W
Q
R
W
L
D
D
D
S
-
S
W----
P
D
-
F
S
---
V
-----
V
V
H
G
D
L
Y
V
G
H
V
L
I
-
D
N
T---
E
R
----
V
S
G
M
I
D
W
S
E
A
R
V
D
D
P
A
I
D
M
A
A
H
L
M
V
F
G
----
E
E
G
L
A
---
K
L
L
L
T
Y
E
A
A
G
G
R
V
W
-
P
R
L
A
--
H
H
I
A
E
R
L
A
F
G
A
--
V
T
Y
A
L
F
A
L
D
S
G
N
E
E
Y
L
A
A
A
K
A
Q
L
A
A
-----
2
PsiBlast_PDB
73.51
32%
2
- C2 -
-
5IGJ
3
?
A:
[40-263]
I
A
T
V
D
D
G
R
R
W
V
L
R
I
P
R
R
A
E
V
S
A
K
V
E
P
E
A
R
V
L
A
M
L
K
N
R
L
P
F
A
V
P
D
W
R
V
ANAE
L
V
A
Y
P
M
----
L
E
D
-
S
T
A
M
V
I
Q
P
G
S
S
T
P
--
D
-----
W
VVPQD--------
S
E
V
F
-------
A
E
S
F
A
T
--------------------
A
L
A
A
L
H
A
V
P
I
S
A
A
V
D
A
G
M
L
IR
T
P
T
Q
A
R
Q
K
V
A
D
D
V
D
R
V
R
R
E
F
------
V
V
N
D
K
R
L
H
R
W
Q
R
W
L
D
D
D
S
-
S
-----
W
P
D
F
S
---
V
-----
V
V
H
G
D
L
Y
V
G
H
V
L
I
-
D
N
T---
E
R
----
V
S
G
M
I
D
W
S
E
A
R
V
D
D
P
A
I
D
M
A
A
H
L
--------
M
V
F
G
E
---
E
G
L
A
K
L
L
L
-----
T
-
Y
E
A
---
A
G
G
R
V
W
P
R
L
A
---------------------------------
14
PsiBlast_PDB
73.44
19%
0
- C2 -
-
5IQI
1
AACA_STAAU
A:
[41-304]
V
A
Y
L
V
N
N
E
-
Y
I
F
K
T
K
F
S
T
N
K
K
K
G
F
A
K
E
K
A
I
Y
N
F
L
N
T
N
L
E
T
N
V
K
I
P
N
I
----
E
Y
S
Y
I
S
----
D
E
L
S
I
L
G
Y
K
E
I
K
G
T
F
L
T
P
E
I
-----
Y
-------------
S
T
M
S
E
E
E
Q
N
L
L
K
R
D
I
A
S
--------------------
F
L
R
Q
M
H
G
L
D
Y
T
D
I
S
E
C
T
I
D
--
N
K
Q
N
V
L
E
E
Y
I
----
L
L
R
E
T
I
----
Y
N
D
L
T
D
I
E
K
D
Y
I
E
S
F
M
E
R
L
N
A
T
-----
T
V
-
F
E
GKK
C
-----
L
C
H
N
D
F
S
C
N
H
L
L
L
D
G
N
----
N
R
----
L
T
G
I
I
D
F
G
D
S
G
I
I
D
E
Y
C
D
F
I
Y
L
L
E
D
S
E
EEIG
T
N
F
G
E
---
D
I
L
R
M
Y
G
N
ID---
I
-
E
K
A
K
--
E
Y
Q
D
I
V
E
E
Y
Y
P
--
I
E
T
I
V
Y
G
I
K
N
I
K
Q
E
F
I
E
N
G
R
K
E
I
Y
K
R
T
Y
K
-
18
PsiBlast_PDB
73.36
19%
-0
- C2 -
-
5BYL
2
AACA_STAAU
A:
[41-304]
V
A
Y
L
V
N
N
E
-
Y
I
F
K
T
K
F
S
T
N
--
K
G
Y
A
K
E
K
A
I
Y
N
F
L
N
T
N
L
E
T
N
V
K
I
P
N
I
----
E
Y
S
Y
I
S
----
D
E
L
S
I
L
G
Y
K
E
I
K
G
T
F
L
T
P
E
I
-----
Y
-------------
S
T
M
S
E
E
E
Q
N
L
L
K
R
D
I
A
S
--------------------
F
L
R
Q
M
H
G
L
D
Y
T
D
I
S
E
C
T
I
D
--
N
K
Q
N
V
L
E
E
Y
I
----
L
L
R
E
T
I
----
Y
N
D
L
T
D
I
E
K
D
Y
I
E
S
F
M
E
R
L
N
A
T
-----
T
V
-
F
E
GKK
C
-----
L
C
H
N
D
F
S
C
N
H
L
L
L
D
G
N
----
N
R
----
L
T
G
I
I
D
F
G
D
S
G
I
I
D
E
Y
C
D
F
I
Y
L
L
E
D
S
E
EEIG
T
N
F
G
E
---
D
I
L
R
M
Y
G
N
ID---
I
-
E
K
A
K
--
E
Y
Q
D
I
V
E
E
Y
Y
P
--
I
E
T
I
V
Y
G
I
K
N
I
K
Q
E
F
I
E
N
G
R
K
E
I
Y
K
R
T
Y
K
-
142
HHSearch
73.18
26%
-29
- C2 -
-
5UXD
2
?
A:
[44-299]
----
D
G
G
D
-
W
V
L
R
L
P
R
R
P
D
V
L
E
R
A
A
V
E
G
R
L
L
A
M
L
A
P
H
L
D
V
A
V
P
D
W
R
I
----
S
T
---------
S
E
-
L
I
A
Y
P
L
L
P
G
S
P
G
L
--
T
-----
V
A
ADG
E
V
S
W
HVDMA
S
T
V
Y
-------
A
R
S
L
G
S
--------------------
V
V
A
Q
L
H
A
V
D
A
E
A
A
A
A
T
G
I
E
V
R
S
P
A
Q
V
R
G
A
W
R
Q
D
L
A
R
V
G
A
E
F
------
E
I
A
P
A
L
R
E
R
W
E
A
W
L
A
D
D
G
-
C
W----
P
G
-
H
S
---
V
-----
L
T
H
G
E
L
Y
P
A
H
T
L
V
-
E
D
----
E
R
----
I
T
A
V
L
D
W
T
T
A
A
V
G
D
P
A
K
D
L
M
F
H
Q
V
S
A
P
----
S
A
I
F
E
---
V
A
L
Q
A
Y
A
E
-----
G
G
G
R
P
W
PG
L
A
R
H
C
T
E
M
F
S
A
A
P
L
G
Y
G
L
Y
A
L
A
T
G
E
A
A
H
R
E
A
A
A
A
A
L
N
P
P
E
E
--
6
PsiBlast_PDB
73.18
32%
4
- C2 -
-
5IGT
3
?
A:
[40-263]
I
A
T
V
D
D
G
R
R
W
V
L
R
I
P
R
R
A
E
V
S
A
K
V
E
P
E
A
R
V
L
A
M
L
K
N
R
L
P
F
A
V
P
D
W
R
V
ANAE
L
V
A
Y
P
M
----
L
E
D
-
S
T
A
M
V
I
Q
P
G
S
S
T
P
--
D
-----
W
VVPQD--------
S
E
V
F
-------
A
E
S
F
A
T
--------------------
A
L
A
A
L
H
A
V
P
I
S
A
A
V
D
A
G
M
L
IR
T
P
T
Q
A
R
Q
K
V
A
D
D
V
D
R
V
R
R
E
F
------
V
V
N
D
K
R
L
H
R
W
Q
R
W
L
D
D
D
S
-
S
-----
W
P
D
F
S
---
V
-----
V
V
H
G
D
L
Y
V
G
H
V
L
I
-
D
N
T---
E
R
----
V
S
G
M
I
D
W
S
E
A
R
V
D
D
P
A
I
D
M
A
A
H
L
--------
M
V
F
G
E
---
E
G
L
A
K
L
L
L
-----
T
-
Y
E
A
---
A
G
G
R
V
W
P
R
L
A
---------------------------------
5
PsiBlast_PDB
73.11
32%
2
- C2 -
-
5IGS
3
?
A:
[40-263]
I
A
T
V
D
D
G
R
R
W
V
L
R
I
P
R
R
A
E
V
S
A
K
V
E
P
E
A
R
V
L
A
M
L
K
N
R
L
P
F
A
V
P
D
W
R
V
ANAE
L
V
A
Y
P
M
----
L
E
D
-
S
T
A
M
V
I
Q
P
G
S
S
T
P
--
D
-----
W
VVPQD--------
S
E
V
F
-------
A
E
S
F
A
T
--------------------
A
L
A
A
L
H
A
V
P
I
S
A
A
V
D
A
G
M
L
I
R
T
P
T
Q
A
R
Q
K
V
A
D
D
V
D
R
V
R
R
E
F
------
V
V
N
D
K
R
L
H
R
W
Q
R
W
L
D
D
D
S
-
S
-----
W
P
D
F
S
---
V
-----
V
V
H
G
D
L
Y
V
G
H
V
L
I
-
D
N
T---
E
R
----
V
S
G
M
I
D
W
S
E
A
R
V
D
D
P
A
I
D
M
A
A
H
L
--------
M
V
F
G
E
---
E
G
L
A
K
L
L
L
-----
T
-
Y
E
A
---
A
G
G
R
V
W
P
R
L
A
---------------------------------
3
PsiBlast_PDB
73.02
32%
1
- C2 -
-
5IGP
3
?
A:
[40-263]
I
A
T
V
D
D
G
R
R
W
V
L
R
I
P
R
R
A
E
V
S
A
K
V
E
P
E
A
R
V
L
A
M
L
K
N
R
L
P
F
A
V
P
D
W
R
V
ANAE
L
V
A
Y
P
M
----
L
E
D
-
S
T
A
M
V
I
Q
P
G
S
S
T
P
--
D
-----
W
VVPQD--------
S
E
V
F
-------
A
E
S
F
A
T
--------------------
A
L
A
A
L
H
A
V
P
I
S
A
A
V
D
A
G
M
L
I
R
T
P
T
Q
A
R
Q
K
V
A
D
D
V
D
R
V
R
R
E
F
------
V
V
N
D
K
R
L
H
R
W
Q
R
W
L
D
D
D
S
-
S
-----
W
P
D
F
S
---
V
-----
V
V
H
G
D
L
Y
V
G
H
V
L
I
-
D
N
T---
E
R
----
V
S
G
M
I
D
W
S
E
A
R
V
D
D
P
A
I
D
M
A
A
H
L
--------
M
V
F
G
E
---
E
G
L
A
K
L
L
L
-----
T
-
Y
E
A
---
A
G
G
R
V
W
P
R
L
A
---------------------------------
1
PsiBlast_PDB
72.73
32%
2
- C2 -
-
5IGI
3
?
A:
[40-263]
I
A
T
V
D
D
G
R
R
W
V
L
R
I
P
R
R
A
E
V
S
A
K
V
E
P
E
A
R
V
L
A
M
L
K
N
R
L
P
F
A
V
P
D
W
R
V
ANAE
L
V
A
Y
P
M
----
L
E
D
-
S
T
A
-
V
I
Q
P
G
S
S
T
P
--
D
-----
W
VVPQD--------
S
E
V
F
-------
A
E
S
F
A
T
--------------------
A
L
A
A
L
H
A
V
P
I
S
A
A
V
D
A
G
M
L
IR
T
P
T
Q
A
R
Q
K
V
A
D
D
V
D
R
V
R
R
E
F
------
V
V
N
D
K
R
L
H
R
W
Q
R
W
L
D
D
D
S
-
S
-----
W
P
D
F
S
---
V
-----
V
V
H
G
D
L
Y
V
G
H
V
L
I
-
D
N
T---
E
R
----
V
S
G
M
I
D
W
S
E
A
R
V
D
D
P
A
I
D
M
A
A
H
L
--------
M
V
F
G
E
---
E
G
L
A
K
L
L
L
-----
T
-
Y
E
A
---
A
G
G
R
V
W
P
R
L
A
---------------------------------
15
PsiBlast_PDB
72.64
19%
-1
- C2 -
-
6CH4
1
AACA_STAAU
A:
[41-304]
V
A
Y
L
V
N
N
E
-
Y
I
F
K
T
K
F
S
T
N
K
K
K
G
Y
A
K
E
K
A
I
Y
N
F
L
N
T
N
L
E
T
N
V
K
I
P
N
I
----
E
Y
S
Y
I
S
----
D
E
L
S
I
L
G
Y
K
E
I
K
G
T
F
L
T
P
E
I
-----
Y
-------------
S
T
M
S
E
E
E
Q
N
L
L
K
R
D
I
A
S
--------------------
F
L
R
Q
M
H
G
L
D
Y
T
D
I
S
E
C
T
I
D
--
N
K
Q
N
V
L
E
E
Y
I
----
L
L
R
E
T
I
----
Y
N
D
L
T
D
I
E
K
D
Y
I
E
S
F
M
E
R
L
N
A
T
-----
T
V
-
F
E
GKK
C
-----
L
C
H
N
D
F
N
C
N
H
L
L
L
D
G
N
----
N
R
----
L
T
G
I
I
D
F
G
D
S
G
I
I
D
E
Y
C
D
F
I
Y
L
L
E
D
S
E
EEIG
T
N
F
G
E
---
D
I
L
R
M
Y
G
N
ID---
I
-
E
K
A
K
--
E
Y
Q
D
I
V
E
E
Y
Y
P
--
I
E
T
I
V
Y
G
I
K
N
I
K
Q
E
F
I
E
N
G
R
K
E
I
Y
K
R
T
Y
K
-
17
PsiBlast_PDB
72.50
19%
4
- C2 -
-
4ORK
1
AACA_STAAU
A:
[41-304]
V
A
Y
L
V
N
N
E
-
Y
I
F
K
T
K
F
S
T
N
K
K
K
G
Y
A
K
E
K
A
I
Y
N
F
L
N
T
N
L
E
T
N
V
K
I
P
N
I
----
E
Y
S
Y
I
S
----
D
E
L
S
I
L
G
Y
K
E
I
K
G
T
F
L
T
P
E
I
-----
Y
-------------
S
T
M
S
E
E
E
Q
N
L
L
K
R
D
I
A
S
--------------------
F
L
R
Q
M
H
G
L
D
Y
T
D
I
S
E
C
T
I
D
--
N
K
Q
N
V
L
E
E
Y
I
----
L
L
R
E
T
I
----
Y
N
D
L
T
D
I
E
K
D
Y
I
E
S
F
M
E
R
L
N
A
T
-----
T
V
-
F
E
GKK
C
-----
L
C
H
N
D
F
S
C
N
H
L
L
L
D
G
N
----
N
R
----
L
T
G
I
I
D
F
G
D
S
G
I
I
D
E
Y
C
D
F
I
Y
L
L
E
D
S
E
EEIG
T
N
F
G
E
---
D
I
L
R
M
Y
G
N
ID---
I
-
E
K
A
K
--
E
Y
Q
D
I
V
E
E
Y
Y
P
--
I
E
T
I
V
Y
G
I
K
N
I
K
Q
E
F
I
E
N
G
R
K
E
I
Y
K
R
T
Y
K
-
145
HHSearch
72.47
23%
-20
- C2 -
-
3TDW
1
?
A:
[39-299]
-----
N
G
D
-
W
V
F
R
F
P
K
S
Q
Q
G
A
D
E
L
N
K
E
I
Q
L
L
P
L
L
V
G
C
V
K
V
N
I
P
Q
Y
V
Y
----
I
G
K
R
S
D
----
G
N
P
-
F
V
G
Y
R
K
V
Q
G
Q
I
L
G
--
E
-----
D
G
M
A
V
LP
D
D
A
----
K
D
R
L
-------
A
L
Q
L
A
E
--------------------
F
M
N
E
L
S
A
F
P
V
E
T
A
I
S
A
G
V
P
--
V
-----
T
N
L
K
N
K
I
L
L
L
S
E
A
V
E
D
QV
F
P
L
L
D
E
S
L
R
D
Y
L
T
L
R
F
Q
S
Y
M
-
T
HPVYT
R
Y
-
T
P
---
R
-----
L
I
H
G
D
L
S
P
D
H
F
L
T
-
N
L
NSRQ
T
P
----
L
T
G
I
I
D
F
G
D
A
A
I
S
D
P
D
Y
D
Y
V
Y
L
L
E
D
C
G
----
E
L
F
-
T
---
R
Q
V
M
A
Y
R
G
EVD--
L
-
D
T
H
I
--
R
K
V
S
L
F
V
T
F
D
Q
--
V
S
Y
L
L
E
G
L
R
A
R
D
Q
D
W
I
S
E
G
L
E
L
L
E
E
D
K
A
N
-
7
PsiBlast_PDB
72.19
32%
6
- C2 -
-
5IGH
-
?
A:
[40-263]
I
A
T
V
D
D
G
R
R
W
V
L
R
I
P
R
R
A
E
V
S
A
K
V
E
P
E
A
R
V
L
A
M
L
K
N
R
L
P
F
A
V
P
D
W
R
V
ANAE
L
V
A
Y
P
M
----
L
E
D
-
S
T
A
M
V
I
Q
P
G
S
S
T
P
--
D
-----
W
V
V
P
QD--------
S
E
V
F
-------
A
E
S
F
A
T
--------------------
A
L
A
A
L
H
A
V
P
I
S
A
A
V
D
A
G
M
L
I
R
T
P
T
Q
A
R
Q
K
V
A
D
D
V
D
R
V
R
R
E
F
------
V
V
N
D
K
R
L
H
R
W
Q
R
W
L
D
D
D
S
-
S
-----
W
P
D
F
S
---
V
-----
V
V
H
G
D
L
Y
V
G
H
V
L
I
-
D
N
T---
E
R
----
V
S
G
M
I
D
W
S
E
A
R
V
D
D
P
A
I
D
M
A
A
H
L
--------
M
V
F
G
E
---
E
G
L
A
K
L
L
L
-----
T
-
Y
E
A
---
A
G
G
R
V
W
P
R
L
A
---------------------------------
20
PsiBlast_PDB
72.10
19%
-2
- C2 -
-
5IQB
2
AACA_STAAU
A:
[41-304]
V
A
Y
L
V
N
N
E
-
Y
I
F
K
T
K
F
S
---
K
K
G
Y
A
K
E
K
A
I
Y
N
F
L
N
T
N
L
E
T
N
V
K
I
P
N
I
----
E
Y
S
Y
I
S
----
D
E
L
S
I
L
G
Y
K
E
I
K
G
T
F
L
T
P
E
I
-----
Y
-------------
S
T
M
S
E
E
E
Q
N
L
L
K
R
D
I
A
S
--------------------
F
L
R
Q
M
H
G
L
D
Y
T
D
I
S
E
C
T
I
D
--
N
K
Q
N
V
L
E
E
Y
I
----
L
L
R
E
T
I
----
Y
N
D
L
T
D
I
E
K
D
Y
I
E
S
F
M
E
R
L
N
A
T
-----
T
V
-
F
E
GKK
C
-----
L
C
H
N
D
F
S
C
N
H
L
L
L
D
G
N
----
N
R
----
L
T
G
I
I
D
F
G
D
S
G
I
I
D
E
Y
C
D
F
I
Y
L
L
E
D
S
E
EEIG
T
N
F
G
E
---
D
I
L
R
M
Y
G
N
ID---
I
-
E
K
A
K
--
E
Y
Q
D
I
V
E
E
Y
Y
P
--
I
E
T
I
V
Y
G
I
K
N
I
K
Q
E
F
I
E
N
G
R
K
E
I
Y
K
R
T
Y
K
-
9
PsiBlast_PDB
72.04
22%
-25
- C2 -
-
3TDV
1
?
A:
[35-293]
-
A
I
L
V
N
G
D
-
W
V
F
R
F
P
K
S
Q
Q
G
A
D
E
L
N
K
E
I
Q
L
L
P
L
L
V
G
C
V
K
V
N
I
P
-------------------
Q
Y
-
V
Y
I
G
K
R
S
D
G
N
P
F
V
--
G
-----
Y
-------------
R
K
V
Q
-------
G
Q
I
L
G
E
DGMAVFP
D
D
A
K
D
R
L
A
L
Q
L
A
E
F
M
N
E
L
S
A
F
P
V
E
T
A
I
S
A
G
V
---
P
V
T
N
L
K
N
K
I
L
L
L
S
E
A
V
E
D
Q
V
----
F
P
L
L
D
E
S
L
R
D
Y
L
T
L
R
F
Q
S
Y
M
-
T
-----
H
P
-
V
Y
---
T
R
Y
T
P
R
L
I
H
G
D
L
S
P
D
H
F
L
T
-
N
L
----
N
S
RQTP
L
T
G
I
I
D
F
G
D
A
A
I
S
D
P
D
Y
D
Y
V
Y
L
L
E
D
C
G
----
E
L
F
T
R
Q
V
M
A
Y
R
G
E
V
D
L
-----
D
-
T
H
I
R
---
K
V
S
L
F
V
T
F
D
Q
--
V
S
Y
L
L
E
G
L
R
A
R
D
Q
D
W
I
S
E
G
L
E
L
L
-------
19
PsiBlast_PDB
71.60
19%
-2
- C2 -
-
5IQA
1
AACA_STAAU
A:
[41-304]
V
A
Y
L
V
N
N
E
-
Y
I
F
K
T
K
F
S
T
N
K
K
K
G
Y
A
K
E
K
A
I
Y
N
F
L
N
T
N
L
E
T
N
V
K
I
P
N
I
----
E
Y
S
Y
I
S
----
D
E
L
S
I
L
G
Y
K
E
I
K
G
T
F
L
T
P
E
I
-----
Y
-------------
S
T
M
S
E
E
E
Q
N
L
L
K
R
D
I
A
S
--------------------
F
L
R
Q
M
H
G
L
D
Y
T
D
I
S
E
C
T
I
D
--
N
K
Q
N
V
L
E
E
Y
I
----
L
L
R
E
T
I
----
Y
N
D
L
T
D
I
E
K
D
Y
I
E
S
F
M
E
R
L
N
A
T
-----
T
V
-
F
E
GKK
C
-----
L
C
H
N
D
F
S
C
N
H
L
L
L
D
G
N
----
N
R
----
L
T
G
I
I
D
F
G
D
S
G
I
I
D
E
Y
C
D
F
I
Y
L
L
E
D
S
E
EEIG
T
N
F
G
E
---
D
I
L
R
M
Y
G
N
ID---
I
-
E
K
A
K
--
E
Y
Q
D
I
V
E
E
Y
Y
P
--
I
E
T
I
V
Y
G
I
K
N
I
K
Q
E
F
I
E
N
G
R
K
E
I
Y
K
R
T
Y
K
-
16
PsiBlast_PDB
71.48
19%
-1
- C2 -
-
5IQH
2
AACA_STAAU
A:
[41-304]
V
A
Y
L
V
N
N
E
-
Y
I
F
K
T
K
F
S
---
K
K
G
Y
A
K
E
K
A
I
Y
N
F
L
N
T
N
L
E
T
N
V
K
I
P
N
I
----
E
Y
S
Y
I
S
----
D
E
L
S
I
L
G
Y
K
E
I
K
G
T
F
L
T
P
E
I
-----
Y
-------------
S
T
M
S
E
E
E
Q
N
L
L
K
R
D
I
A
S
--------------------
F
L
R
Q
M
H
G
L
D
Y
T
D
I
S
E
C
T
I
D
--
N
K
Q
N
V
L
E
E
Y
I
----
L
L
R
E
T
I
----
Y
N
D
L
T
D
I
E
K
D
Y
I
E
S
F
M
E
R
L
N
A
T
-----
T
V
-
F
E
GKK
C
-----
L
C
H
N
D
F
S
C
N
H
L
L
L
D
G
N
----
N
R
----
L
T
G
I
I
D
F
G
D
S
G
I
I
D
E
Y
C
D
F
I
Y
L
L
E
D
S
E
EEIG
T
N
F
G
E
---
D
I
L
R
M
Y
G
N
ID---
I
-
E
K
A
K
--
E
Y
Q
D
I
V
E
E
Y
Y
P
--
I
E
T
I
V
Y
G
I
K
N
I
K
Q
E
F
I
E
N
G
R
K
E
I
Y
K
R
T
Y
K
-