Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDESGGEARAYMLGSGIVVKTQRPHRLRPRTSLEKEAHVLSLLAGPLAGRIPRLFGYGREDTAAGPVEFLVMSRIRGCAALHAGL-----PAREALLASLADVLRSVHAADVTGLRDSGLL----PADVDSAALRGRLQLGFADACDGFAAHRDRYAGAGAPERIAIAAVDALAG--LTDESPVLLHSNPGPTHV-FVGDGGLCTGLIDFGDAYASHPALDLRSWPDPADRIVLHEAYTGGRPTTRGFDAVWTVVMILADLNAMLHRADLAEAAGRDLALRLAQL 5C4L Chain:A ((50-252)) ---KGNDCIAYEINRDFIFKF--PKHSRGSTNLFNEVNILKRIHNKLPLPIPEVVFTGMP-SETYQMSFAGFTKIKGVPLTPLLLNNLPKQSQNQAAKDLARFLSELHSINISGFKSNLVLDFREKINEDNKKIKKLLS---------------RELKGPQMKKVDDFYRDILENEIYFKYYPCLIHNDFSSDHILFDTEKNTICGIIDFGDAAISDPDNDFIS-------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 5C4L.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 656 -22344 -34.06 -116.98 target 2D structure prediction score : 0.55 Monomeric hydrophicity matching model chain A : 0.67 3D Compatibility (PKB) : -34.06 2D Compatibility (Sec. Struct. Predict.) : 0.55 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.226

(partial model without unconserved sides chains): PDB file : Tito_5C4L.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5c4l-query.scw PDB file : Tito_Scwrl_5C4L.pdb: