Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MPLGPEGVTRGWLGAALGRDVSDLRLVRVGVDEGFTGTRLYRAEIGGGASVIVKLASEDAALRARFAAENAREVAFYHHYAE--GLPVPRCYHAASDA---------EAGASVVVLEDLGGARSVPFVTGLSRDEAEAAVRALARCHAAHWGAAGLADLPGAS-VAQEL-GFAACWDGYAQALQGLLPGADLSPEVLALGAAMARDAAAVLGPI-LDDGVLTLRHGDVQADNLMFDG----PGAVLLDWQFMARGRGGSDLAYLLISSLEPEVRRAHEAALIACYLNALQEQGIAYEHAALWRDYRRGVAVKLLMSVVATVGMDNQGAAKQAWRRADLARLLAFAADHGAGEAA 6EF6 Chain:A ((51-292)) ---------------------------------LSENA-TYLVEDG-EHQSILRVHRQDYHQP----HEIESELDWLAALRTDSDVTVPTVVPARDGRRVVTVDPAD-VPRHVVHFEMVGGAEPDEE--SLTLDDFQTLGRITASLHEHSQRWTRPAGFGRFSWDWEHCLGDTPRWGRWQDAE-------GVGASETALLTRAQDLLHRKLEEYGSGPDRYGLIHADLRLANLLVDSSTPQRTITVIDFDDCGFGWYFYDFGTAVSFIEHDPRLGEWQESWVAGYRSR------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 6EF6.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 896 -20871 -23.29 -94.44 target 2D structure prediction score : 0.66 Monomeric hydrophicity matching model chain A : 0.60 3D Compatibility (PKB) : -23.29 2D Compatibility (Sec. Struct. Predict.) : 0.66 1D Compatibility (Hydrophobicity) : 0.60 QMean score : 0.228

(partial model without unconserved sides chains): PDB file : Tito_6EF6.pdb: (Unconserved sides chains are recalculated) : Sequence: align-6ef6-query.scw PDB file : Tito_Scwrl_6EF6.pdb: