Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MMKKVPEFVVQFSPESFSLTPVPGGLSNHNYRLQFQQHGLNNRYFVRQFSATYLGMDNDVELEYAAQIQAANIGLA-PNVIVKHK-QGMICDWVTGE-HWDQTAQVRDENIEKLAQLVAMLHQQPMPSHH-LDMVERLQHYYQTLNTEFKTVQLAQQLTLVIDLIEQH-LPANRLGFCHHDMNPLNFIEDEQAKLYLLDWEFAAAGHCDFDIATLFQTFEWQDAQQALFIRYYNQYYPAAKVTFEQLDVMAVVVEMMTLLWCIVMYQQDKDATYLRLWQQSEYAITDKINRLSKELQWDQ 4R78 Chain:A ((29-304)) ----ISSLLSQE-EEVLSVEQL-GGMTNQNYLAKTT----NKQYIVKFFGKGTE-KLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTS--IKTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLEKRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTSQEEETFLSHYESDQT--PVSHEKIAIYKILQDTIWSLWTVYKEEQ--GEDFGDYGVNRYQRAVKGLASYG-------

General information: TITO was launched using: RESULT: Template: 4R78.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1288 -15061 -11.69 -55.57 target 2D structure prediction score : 0.66 Monomeric hydrophicity matching model chain A : 0.69 3D Compatibility (PKB) : -11.69 2D Compatibility (Sec. Struct. Predict.) : 0.66 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.353

(partial model without unconserved sides chains): PDB file : Tito_4R78.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4r78-query.scw PDB file : Tito_Scwrl_4R78.pdb: