Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNRLHAFIDLDRGAVADLTADYSLGELRSVEPLVTGIINTNYV-LRTDA-GDFLLRLYPPERSADALRFEFSTLARLAEANFPCPRVIANREGKTVAWSEAHARHYAVLEFIPGTTLPRE-------AIDAGVVDQIGSLFADMQRTLSGFVPEGDKPRADLEFVRELGQATLDRIAALP-GEGPATAERLRQVWARSHARFDQPKGSVPALERGVVHADLYFDNVIVEGD----QIRGVIDFDDSYFGLFLIDLAVTLMEFTFVEADALDFELGERLLRRYYARRPEAKGEAHLLHDGMI-CACYKYLGYTADLPEYA-GE----ALLGNEYIARIDYLARPEIRAKVEAMIAAAVEVPA 3CSV Chain:A ((4-318)) ---------SREDEIRDFLATHGY-ADWNRTP--------RYQRLRSPTGAKAVLMDWSPE-EGGDTQPFVDLAQYLRNLDISAPEIYAEEH----------ARGLLLIEDLGDALFTEVINNDPAQEMPLY--RAAVDLLIHLHDAQTPELARL-DPETLSEMTRLAFSEYRY--AILGDAAEDNR--KRFEHRFAQILSA------QLEGDMVFVHRDFHAQNLLWLPEREGLARVGVIDFQDAKLGHRAYDLVSLLQDARR----DVPAQVEAQMIDHYIQATGVDESHFRSAYAVIAVQRNMRILGIFAR-LSQRFGKRHYIEFVPRVWAHFERGLAHPALASAAEEILN-------

General information: TITO was launched using: RESULT: Template: 3CSV.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1315 -18971 -14.43 -66.10 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : -14.43 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.326

(partial model without unconserved sides chains): PDB file : Tito_3CSV.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3csv-query.scw PDB file : Tito_Scwrl_3CSV.pdb: