Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTPGDRMMASALGSWTRLAPFAGLDPAAFEAEELWRREDP------GQVRIVLRMRGGAGQDLVFKRVFQPQDRGRWAEALDGQRRAVR---------ALMRDPVHVPPAILAEDAETLSTVQDFVPGRTLQDHMLLRFDKPGARAQVLQRAGRFLAAFH-GATAEGDKP------FNPATMLDYIRALGRRALSGDLT--LADPDLFAVLAEGLEAAAQTAAGQPVRVAAQHGDLHARNLIVSGKRATLIDFAQDRSAPVQYDMARLIVDLGARFSG--------DAAPEATCGLPAA-DLAALSDGYGRDLSQDACLAFLCRCRVLQDWAALPAVASQRSAFQQERLLQLQKTATRLAAA-- 1B6C Chain:B ((14-339)) TTLKDLIYDM-------TTSGSGSGLPLLVQRTIARTIVLQESIGKGRFGEVWRGK-WRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWL---------VSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNIL----------VKKNGTCCIAD---LG-LAVRHDSATDTIDIAPNHRVGTKR-YMAPEVL-----DDSINM-KHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQLSQQEG

General information: TITO was launched using: RESULT: Template: 1B6C.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 1503 1554 1.03 5.34 target 2D structure prediction score : 0.56 Monomeric hydrophicity matching model chain B : 0.65 3D Compatibility (PKB) : 1.03 2D Compatibility (Sec. Struct. Predict.) : 0.56 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.282

(partial model without unconserved sides chains): PDB file : Tito_1B6C.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1b6c-query.scw PDB file : Tito_Scwrl_1B6C.pdb: