Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence -------------MCINFLVCASLSMFRTSVSGARVP----IGA-----WPDRGGEVRDAVLSVFRRNEYMREIDTG-----------------ARVASPG-------TGCD-----GLVGTCPVDKPVDSVAVGVLARFLAQLTLVRKEALPAL------PAEWSRNERDSRAYLDTLVRHAKRRMLD-------PN------WTAIGGLFAVLGVPGDRLVRFAEQVP---AMSRRPYGLLLTNLARDN---VTILEGPKLAEAGLDWTSASYGDPLHGLAGHVVRMRYPQDQVNEVVQAWACEMRRIRPPAVSGLDRDLPYYLDFERIHAAYDDVIRAARSLGDSIENLALLAAASDIGTALKRAAGLLGMSEVPPEKEIADALFRWQAARLVRAAERVPDSLFRWRC--DDRVPERDDFPSDLVRRALAVEGVAPADRVFRGTAHLNTVVQLENYPDPVVVRRETAAAPRREQGLLPEHAVLQVIERSGVQVRAPRILALGYDDRRRHVAIHTYEGPGGRSPQHPVDGLLP---AEADELVDELAALAEVD-----------HSSLPSNEPE--------GGFYRWLAERLADFVAALPDATLRAADQRGLPDGDLLRQILGRYKVSDRAPVLLHGDLNPWNLVRAGRQGGLTIIDWEMGM-IGDPLYDLVRHLHLTPTRTEMRVRMFDRWSKKLPAECVVGWEEDWRVYRYIEQIRSAYVDLDRMTTGAA---------LSTPNVRRAVDAYEMTLSAATGSLGLRRRV----VPKVPASLKVS------------------------------------------------------------------------------------------------------------------------ 1KBL Chain:A ((1-872)) AKWVYKFEEGNASM-RNLLGGKGCNLAEMTILGMPIPQGFTVTTEACTEYYNSGKQITQEIQDQIFEAITWLEELNGKKFGDTEDPLLVSVRSGARASMPGMMDTILNLGLNDVAVEGFAKKTGNPRFAYDSYRRFIQMYSDVVMEVPKSHFEKIIDAMKEEKGVHFDTDLTADDLKELAEKFKAVYKEAMNGEEFPQEPKDQLMGAVKAVFRSWDNPRAIVYRRMNDIPGDWGTAVNVQTMVFGNKGETSGTGVAFTRNPSTGEKGIYGEYLINAQG-EDVVA-GVRTPQPITQLENDMPDCYKQFMDLAMKLEKHFRDMQDMEFTIEEGK-LY---FLQTRNGKRT-APAALQIACDLVDEGMITEEEAVVRIE-------AKSLDQLLHPTFNPAALKAGEVIGSALPASPGAAAGKVYFTADEAKAAHEKGERV---ILVRLETSPEDIEGMHAA-EGILT--VRGGMTSHAAVVARGMGTCCVSGCGEIKINEEAKTFELGGHTFAEGDYISLDGSTGKIYKGDIETQEASVSGSFERIMVWADKFRTLKVRTNADTPEDTLNAVKLGAEGIGLCRTEHMFFEADRIMKIRKMILSDSVEAREEALNELIPFQKGDFKAMYKAL-EGRPMTVRYLDPPLHEFVPHTEEEQA-----ELAKNMGLTLAEVKAKVDELHEFNPMMGHRGCRLAVTYP--------E--IAKMQTRAVMEAAIEVKEETGIDIVPEIMIPLVGEKKELKFVKDVVVEVAEQVKKEKGSDMQYHIGTMIEIPRAALTADAIAEEAEFFSFGTNDLTQMTFGFSRDDAGKFLDSYYKAKIYESDPFARLDQTGVGQLVEMAVKKGRQTRPGLKCGICGEHGGDPSSVEFCHKVGLNYVSCSPFRVPIARLAAAQAALNN

General information: TITO was launched using: RESULT: Template: 1KBL.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 3576 83194 23.26 130.40 target 2D structure prediction score : 0.62 Monomeric hydrophicity matching model chain A : 0.61 3D Compatibility (PKB) : 23.26 2D Compatibility (Sec. Struct. Predict.) : 0.62 1D Compatibility (Hydrophobicity) : 0.61 QMean score : 0.205

(partial model without unconserved sides chains): PDB file : Tito_1KBL.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1kbl-query.scw PDB file : Tito_Scwrl_1KBL.pdb: