Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence -----MADSARYTFNMAGIIMHPGEKRVLLRAVQGGWMLPQVEWQADEYSSWKEVARFNREMQGLLDVCLSTVRCLGEDFERATMHFSRIYVMELHSSYDNLPADAC-WIDIEDLKEFMITPEEHLVWLEEWLAKRDEEERTPWYHPDWLAKAKVWIEQALAEPEAQPLVSIEQVGVAERGCLLRVQTKENAFYFKALPAFFRHELTLLQHLARYRVGCVPALVAVDEREHRLLM-HDFGSKHLDQSLDLADWQEALRRYAILQI-DHIQIDHIQIDHSAQVEQLEELGCPRLPLATLPDQLERLLTSEQSLLFDTPT-ALSLEQVRRL------------------HDALPLIRSLCQELAGYGLPETL-EHGDLHAQNIAL-SGGDYLYFDWTDSCIAHPFFSLYPFLLDI-----EARWPEARIRLREAYLQPWERYAARAQLVEAFELAQRLAPLHLAMLYATLIIPHMKARWEMQHGVPLNLKVLLDRLHDAG--- 4D0L Chain:A ((10-566)) SWLLRLFESKLFDISMAISYLYNS-KEPGVQAYIGNRLFCFRNEDVDFY------------LPQLLNMYIHMDEDVGDAIKPYIVHRCRQSINFSLQCALLLGAYSSRGTKLRKLILSRLAPEREFIKSLMAIGKRLATLPT-------KEQKTQRLISELSLLNHKLPARVWLPTAGFDHHVVRVPHTQAVVLNSKDKAPYLIYVEVLE-CENFDTTSVPARIPENPSAVALKEPWQEKVRRIREGSPYGHLPNWRLLSVIVKCGDDLRQELLAFQVLKQLQSIWEQ--ERVPLWIKP--YKILVISADSGMIEPVVNAVSIHQVKKQSQLSLLDYFLQEHGSYTTEAFLSAQRNFVQSCAGYCLVCYLLQVKDRHNGNILLDAEGHIIHIDFGFILSSSSAFKLTTEFVDVMGGLDGDMFNYYKMLMLQGLIAARKHMDKVVQIVEIMQQGSQL-----PCFHGSSTIRNLKERFHMSMT-EEQLQLLVEQMVDGSMRS

General information: TITO was launched using: RESULT: Template: 4D0L.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2061 -25070 -12.16 -57.90 target 2D structure prediction score : 0.52 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : -12.16 2D Compatibility (Sec. Struct. Predict.) : 0.52 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.189

(partial model without unconserved sides chains): PDB file : Tito_4D0L.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4d0l-query.scw PDB file : Tito_Scwrl_4D0L.pdb: