Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTGAGAADATEDAATDATRGTDATRGTDATGGTDGPVPAARTAEEDRLVARVEELVGG--RVTAIERQ--PRWRKAWYLTVDRDGAELALYVRGDKQIDAEPYPGLDREAAILRILERNGVPVPHVHGMSSD-----PIGIIMDRVPGTRDVAEA---ADDAQRRGIAEQYMEILARMHSIDVAEFAAAGIEVPTTPEGAQLAFVDANERLYRRTKKAPEPLVEWALRWARRRLPT-AGNRARFIHGDTG--QFLFVD--GRITCVYDFEASHIGDPLSDLAGLRTRAGTE-------------PLG-ADIEHMIRHYQRVAGTTIDPSALSFYTATYMLTAVMALSGPLTELRPADQQAEYLTWDLMVRRAMLWAIAEVEGVKIEPAPPVTLPTGYPARVTTVLEGTVRRMVPATGVDEANQSAALALAQWAGAMVAVGMANVERDLDRAAVLLGHRPADQAAADAELERFVLAAGPEHDLALLEYFAAQTEARVAEAVPMRTRLEQYALPKVVL 3DXP Chain:A ((20-330)) -----------------------------------------RFDTEALEAWMRQHVEGFAGPLSVEQFKG-QSNPTFKLVTP----GQTYVMRAKPG-------AIEREYRVMDALAGTDVPVAKMYALCEDESVIGRAFYIMEFVSGRVLWDQSLPGMSPAERTAIYDEMNRVIAAMHTVDYQAIGLGD---YGKPGNYFQRQIERWTKQYKLSETESIPAMDSLMDWLPQHIPQEDADLTSIVHGDYRLDNLMFHPTEPRVLAVLDWELSTLGHPMGDFGYHCMSWHIAPGQFRGIAGLDHAALGIPDEASYRKLYEQRTGRPIT-GDWNFYLAFSMFRIAGILQGIMKRVVDGT---------------------------------------------------------------------------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 3DXP.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1150 -2401 -2.09 -8.93 target 2D structure prediction score : 0.73 Monomeric hydrophicity matching model chain A : 0.63 3D Compatibility (PKB) : -2.09 2D Compatibility (Sec. Struct. Predict.) : 0.73 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.264

(partial model without unconserved sides chains): PDB file : Tito_3DXP.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3dxp-query.scw PDB file : Tito_Scwrl_3DXP.pdb: