Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSASISAAADPRLQQAITWLNTLKTQFGLDLDSLQAASSDASFRRYFRLQAQNRSLILM-DAPPAT-EDCKPFVQVTQLLAPTGIHVPDILAADTEQGFLLLSDLGQDNFQTALKTPMPQSELD-KLYRSTLLTLVKLQQADTTGLPPYNEQRLLE-ELQVFPEWYVQKHRQFELSEKDHNMLRKTFAELVQANVQSAT-VLVHRDFHSPNLMM--PLPGQTEPGVIDYQDALAGPITYDIASLVMDARVTWTEEQQLDWA-IRYWQAAMEAGLDVPADFAVFHQQYEWMSLQRNLRILGVFARLSLRDGKHHYLDHMPRLLGYVHQVAS--RYESFNGLLRLLNRLEGRQTVLGMTV 3CSV Chain:A ((4-333)) ----------SREDEIRDFLAT------------HGYADWNRTPRYQRLRSPTGAKAVLMDWSPEEGGDTQPFVDLAQYLRNLDISAPEIYAEEHARGLLLIEDLGDALFTEVINN---DPAQEMPLYRAAVDLLIHLHDAQTPELARLDPETLSEMTRLAFSEYRYAILG--DAAEDNRKRFEHRFAQILSAQLEG-DMVFVHRDFHAQNLLWLPEREGLARVGVIDFQDAKLGHRAYDLVSLLQDARRDV--PAQVEAQMIDHYIQATGV------DESHFRSAYAVIAVQRNMRILGIFARLSQRFGKRHYIEFVPRVWAHFERGLAHPALASAAEEILNALPAPAPEVLERLRA

General information: TITO was launched using: RESULT: Template: 3CSV.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1501 -6486 -4.32 -20.79 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain A : 0.72 3D Compatibility (PKB) : -4.32 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.399

(partial model without unconserved sides chains): PDB file : Tito_3CSV.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3csv-query.scw PDB file : Tito_Scwrl_3CSV.pdb: