Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSTRRPEIPADLRQWIAEMTGT--DVVEVRQVPGGASRQAWFVDAGTGARSRALFLRYDPREADPGSAFHPLQVEAEIMAELHRHGVTVPQVIAAHPTL-----QAVLLERVGGDTWFRLIQ---DPDEQVRTARDFIGKLAALHRIDAQHLTIPSLGPAGPVAGHVRAEIAAMRARLS-RYGKPAPLLAFCIDWLDRHVPDY-DGPTVMVQGDTGPGNFMYSGG--VVTAVVDWELAHFGDPMDDIAWLSLRTV---------------QDTFTDFPARLAEYEQLSGHRIDDDRVWYYRLFAETRLASISPGSIDTRASVPPASPDAGNSLIYGMLHRRLLVEALAHVVGIPEVDVELPPEGDADAPSEHSSVYEAAASAMSGAAARSTDALALRYVKGAARLVKYLAEVDRIGAVVDAQETAELTAVLGWAPRSVSQGRAALAELAGRGDLTDRDYVTQLWRGIKHDDYLTRTASGALARRTWPPLRHPVPPPSVEQGDRDRWVSPSPKTTVS 3DXP Chain:A ((20-332)) -----RFDTEALEAWMRQHVEGFAGPLSVEQFKG-QSNPTFKLVTP----GQTYVMRAKPG---------AIEREYRVMDALAGTDVPVAKMYALCEDESVIGRAFYIMEFVSGRVLWDQSLPGMSPAERTAIYDEMNRVIAAMHTVDYQAIGLGDYGK---PGNYFQRQIERWTKQYKLSETESIPAMDSLMDWLPQHIPQEDADLTSIVHGDYRLDNLMFHPTEPRVLAVLDWELSTLGHPMGDFGYHCMSWHIAPGQFRGIAGLDHAALGIPDEASYRKLYEQRTGRPIT-GDWNFYLAFSMFRIAGILQGIMKRV----VDGTAS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 3DXP.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1181 -17093 -14.47 -62.61 target 2D structure prediction score : 0.65 Monomeric hydrophicity matching model chain A : 0.63 3D Compatibility (PKB) : -14.47 2D Compatibility (Sec. Struct. Predict.) : 0.65 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.290

(partial model without unconserved sides chains): PDB file : Tito_3DXP.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3dxp-query.scw PDB file : Tito_Scwrl_3DXP.pdb: