Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDTATADIIAGLRAAGL-----TG--E--GEVVLEPLTGGVSCDVWRVDGPAGPIVVKRPLEQLRVAAE-WHAPVERGASEVRWLRRARGVDPHLVPEVLAELP-GHGFAMRFLPD-CPVWKDELIAGRVDPAFAAAVGRGIVAVHAATANSAAD-------RDAFP---------TDAMFR--ALRVDPFLLFV-AQK---------DAELASALYALADDLSSRKVALVHGDVSPKNILVGADGPVFLDAECAVYGDPAFDLAFCTTHLLLKAVWLG--H--------------ERLGEAAAALVEAYRAGIDWE----------------------DA---DALALRAGKLTAALLLARVEG---KSPAPYLTDPHHKQIVRDQAR----ALLLA---PTPIDALVANWKRTKE 2PYW Chain:A ((9-418)) ---LNEKSLVDYIKSTPALSSKIGADKSDDDLVIKEVGDGNLNFVFIVVGSSGSLVIKQALPYIRCIGESWPMTKERAYFEATTLRKHGNLSPDHVPEVYHFDRTMALIGMRYLEPPHIILRKGLIAGIEYPFLADHMSDYMAKTLFFTSLLYHDTTEHRRAVTEFCGNVELCRLTEQVVFSDPYRV-STFNRWTSPYLDDDAKAVREDSALKLEIAELKSMFCERAQALIHGDLHTGSVMVTQDSTQVIDPEFSFYGPMGFDIGAYLGNLILAFFAQDGHATQENDRKEYKQWILRTIEQTWNLFNKRFIALWDQNKDGPGEAYLADIYNNTEVLKFVQENYMRNLLHDSLGFGAAKMIRRIVGVAHVEDFESIEEDKRRAICERSALEFAKMLLKERRKFKSIGEVVSAIQQ---

General information: TITO was launched using: RESULT: Template: 2PYW.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1466 -38479 -26.25 -120.62 target 2D structure prediction score : 0.70 Monomeric hydrophicity matching model chain A : 0.69 3D Compatibility (PKB) : -26.25 2D Compatibility (Sec. Struct. Predict.) : 0.70 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.496

(partial model without unconserved sides chains): PDB file : Tito_2PYW.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2pyw-query.scw PDB file : Tito_Scwrl_2PYW.pdb: