@TOME V3
(Feb 2022)
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
3D Alignment Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
3D Alignment Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
PDB Ligands
Affinity Score
Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
Sequence Alignment
Tab of Complexes
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : CG050_HUMAN: (2020-01-31 )
MAKQKRKVPEVTEKKNKKLKKASAEGPLLGPEAAPSGEGAGSKGEAVLRPGLDAEPELSPEEQRVLERKLKKERKKEERQRLREAGLVAQHPPARRSGAELALDYLCRWAQKHKNWRFQKTRQTWLLLHMYDSDKVPDEHFSTLLAYLEGLQGRARELTVQKAEALMRELDEEGSDPPLPGRAQRIRQVLQLLS
Atome Classification :
(20 SA)
-----------------------.........10-------....----.....20...---.-..----..-30----------.........-40--------------....--.--------.-...50----.....-...60..-......70...---...-..80....--------------.....90........100..--.....-110-.......--.120------.....-----....130..------------.....---------140.----..-----------.-.-..150-----.....-.-...160.---------.-..-----...-170..----..----------...-----------180.......190------...
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
-----------------------MAKQKRKVP
E
--------
V
T
E
K
----
K
N
K
K
L
KKASA---E-GP----LL-G-----------PEAAPSGEG-A---------------GSKG--
E
--------
A
-
V
LRPG----LDAEP-ELS
P
E
E
Q
-
R
V
L
E
R
K
L
K
K
E
R
---
K
K
E
-
E
R
Q
-
R
L
R
E--------------AGLVAQHPPARRS
G
A
E
L
A
L
D
--
Y
L
C
R
W
-
A
Q
--KHKN
W
R
F
--
Q
K
--------
T
R
Q
T
W
-----
L
L
L
H
M
YDSD------------KV
P
D
E
---------
H
F
S
T
----
L
L
-----------
A
-
Y
-
L
E
G
-------LQG
R
A
-
R
-
E
L
T
V
Q
K
A
---------
E
-
A
L
-----
M
R
E
-
L
D
EEG----SD----------PPL-----------P
G
R
A
Q
R
I
R
Q
V
L
Q
-------LLS
30
Fugue
68.18
19%
105
- C3 -
-
3A98
-
ELMO1_HUMAN
B:
[530-727]
-------------------SGPI
L
E
L
K
E
K
I
Q
P
E
--------
I
L
E
L
----
I
K
Q
Q
R
L
N
R
L
V
---
E
-
G
T
----
C
F
-
R
---------------------------------------
K
L
--
N
--------
A
-
R
R
R
Q
D
----
K
F
W
Y
C
-
R
L
S
P
N
H
K
-
V
L
H
Y
G
D
L
E
E
S
P
---
Q
G
E
-
V
P
H
-
D
S
L
Q
--------------
D
K
L
P
V
A
D
I
K
A
V
V
T
G
K
D
--------
C
P
H
M
N
K
--
E
V
L
E
L
A
F
--
S
I
--------
L
Y
D
S
N
-----
C
Q
L
N
F
I
----------------
A
P
D
K
---------
H
E
Y
C
----
I
W
-----------
T
-
D
G
L
N
A
-------
L
L
G
K
D
M
S
-
D
L
T
R
N
D
L
---------
D
-
T
L
-----
L
S
E
M
I
K
L
R
L
----
L
D
LENIQIPDAP
P
P
I
-----------
P
K
E
P
S
N
Y
D
F
V
Y
D
-------
C
N
-
28
Fugue
64.01
18%
5
- C3 -
-
2R5S
4
?
A:
[6-176]
-----------------------
D
E
Q
L
L
K
Q
V
S
E
--------
L
L
Q
Q
----
G
E
H
A
Q
A
L
N
V
I
---
Q
-------
T
L
-
S
-----------
D
E
L
Q
S
R
G
D
V
-
K
---------------
L
A
K
A
--
D
--------
C
-
L
L
E
T
K
-------
Q
F
-
E
L
A
Q
E
L
L
-
A
T
I
P
L
E
Y
Q
D
N
S
---
Y
K
S
-
L
I
A
-
K
L
E
L
--------------
H
Q
Q
A
A
E
S
P
E
L
K
R
L
E
Q
E
L
A
A
N
--
P
------------------
D
N
--------
F
E
L
A
C
-----
E
L
A
V
Q
Y
N
Q
V
------------
G
R
D
E
E
---------
A
L
E
L
----
L
W
-----------
N
-
I
-
L
K
V
-------
N
L
G
-
A
-
Q
-
D
G
E
V
K
K
T
---------
F
M
D
I
-----
L
S
A
-
L
G
Q
G
-------------------------------
N
A
I
A
S
K
Y
R
R
Q
L
Y
-------
S
I
L
22
Fugue
63.55
17%
90
- C5 -
-
4Q3K
1
?
A:
[20-260]
---------------------QG
M
N
I
S
K
I
T
I
N
Q
HVGVTLTC
Y
V
Q
D
----
V
S
Q
E
M
S
N
M
S
K
---
R
-
P
A
----
M
L
-
I
FPGGGYQFCSD
R
E
A
E
P
I
A
L
S
-
Y
---------------
L
A
K
G
YN
A
--------
F
-
V
L
R
Y
S
----
V
K
E
H
A
-
V
F
-
P
R
P
L
-
I
D
A
E
D
A
L
S
Y
L
K
---
D
N
A
-
H
A
L
-
H
I
N
P
DKIAVIGFSAGGHL
A
T
T
L
A
T
E
G
K
V
R
P
N
A
V
V
L
G
Y
P
--
A
L
I
R
H
-
E
K
YW
N
F
P
T
P
K
V
--
D
Q
--------
Q
T
P
E
M
-----
F
V
F
H
T
F
E
D
D
------------
L
V
P
L
S
---------
H
P
L
Y
----
I
V
-----------
E
-
E
-
L
S
K
--------
A
N
I
P
-
V
-
E
F
H
L
F
K
S
GVHGLSLGN
K
-
I
V
-----
S
N
G
-
L
D
K
M
I
----
E
D
----------
D
V
Q
-----------
V
W
F
D
L
S
C
R
W
L
D
K
-------
V
L
D
24
Fugue
60.47
18%
64
- C3 -
-
4MTE
-
ZUR_ECOLI
A:
[4-152]
---------------------TT
T
Q
E
L
L
A
Q
A
E
K
--------
I
C
A
Q
----
R
N
V
R
L
-------------------------------------------------------------------------------------------
T
P
Q
R
L
-
E
V
L
-
R
L
M
S
L
Q
D
---
G
A
I
-
S
A
Y
-
D
L
L
D
--------------
L
-
L
R
E
A
E
P
Q
A
K
P
P
T
V
Y
R
A
L
D
--
F
L
L
E
Q
-
G
F
--
V
H
K
V
------
E
--------
S
T
N
S
Y
-----
V
L
C
H
L
F
D
----------------
Q
P
T
---------
H
T
S
A
----
M
F
-----------
I
-
C
-
D
R
C
---------
G
A
V
-
K
-
E
E
C
A
E
G
V
---------
E
-
D
I
-----
M
H
T
-
L
A
A
K
M
----
G
F
----------
A
L
R
-----------
H
N
V
I
E
A
H
G
L
C
A
A
-------
C
V
E
35
Fugue
59.68
11%
-75
- C5 -
-
1K3E
-
CEST_ECO57
A:
[1-146]
-----------------------------------------
M
S
S
R
----
S
E
L
L
L
E
K
F
A
E
---
K
-
I
G
----
I
G
-
S
-----------
I
S
F
N
E
N
R
L
C
-------------------------------------------------------
S
-
F
A
I
D
E
I
Y
Y
I
S
L
---
S
D
A
-
N
D
E
-
Y
M
M
I
--------------
Y
G
V
C
G
K
F
P
T
D
N
S
N
F
A
L
E
I
L
N
--
A
N
L
W
F
-
A
E
--
N
G
G
P
Y
L
C
--
Y
E
--------
A
G
A
Q
S
-----
L
L
L
A
L
R
F
P
L
------------
D
D
A
T
------------------------------------
P
E
-------
K
L
E
N
E
-
I
-
E
V
V
V
K
S
M
---------
E
-
N
L
-----
Y
L
V
-
L
H
N
Q
G
----
I
T
----------
L
K
I
-----------
E
E
I
S
S
-----------------
36
Fugue
56.69
18%
76
- C4 -
-
5DWB
-
T2A1_THAGE
A:
[1-278]
--------------MRLDLDFGR
G
L
V
A
H
V
M
L
D
N
--------
V
S
E
E
----
Q
Y
Q
Q
I
S
D
Y
F
V
------
P
----
L
V
-
N
-----------
K
P
K
L
K
S
R
D
A
-
I
---------------
G
Q
A
F
--
V
--------
M
-
A
T
E
V
C
----
P
D
A
N
P
-
S
D
L
W
H
---
H
V
L
Y
R
I
Y
I
R
E
K
IG-
T
D
P
-
S
Q
S
-
W
V
R
T
--------------
S
G
E
A
F
E
V
A
L
V
E
R
Y
N
P
V
L
A
R
H
GI
R
L
T
A
L
-
F
K
--
G
Q
K
G
L
A
L
--
T
R
MGVADRVG
S
R
K
V
D
-----
V
M
I
E
K
Q
G
G
G
------------
R
S
P
D
A
EGFGVVGGI
H
A
K
V
----
S
L
-----------
A
E
R
-
V
S
D
-------
D
I
P
A
S
-
R
-
I
M
M
G
E
G
L
---------
L
-
S
V
-----
L
S
T
-
L
D
V
K
S
----
F
P
----------
P
P
H
GDLVNRGELGT
P
D
R
P
S
D
K
R
N
Y
I
E
GHGDFSA
C
F
S
26
Fugue
49.66
11%
37
* C4 *
-
1XO5
-
CIB1_HUMAN
A:
[4-183]
-----------------------
L
L
A
E
Y
Q
D
L
T
F
--------
L
T
K
Q
----
E
I
L
L
A
H
R
R
F
C
---
E
-
L
L
----
P
Q
-
E
-----------
Q
R
S
V
E
S
S
L
R
-
A
---------------
Q
V
P
F
--
E
--------
Q
-
I
L
S
L
-------
P
E
L
-
K
A
N
P
F
K
E
-
R
I
C
R
V
F
S
T
S
P
A
---
K
D
S
L
S
F
E
-
D
F
L
D
--------------
L
L
S
V
F
S
D
T
A
--------------------------------
T
P
--------
D
I
K
S
H
-----
Y
A
F
R
I
F
D
F
D
------------
D
D
G
T
L
---------
N
R
E
D
----
L
S
-----------
R
-
L
-
V
N
C
-------
L
T
R
L
S
-
A
-
S
E
M
K
Q
L
I
---------
D
-
N
I
-----
L
E
E
-
S
D
I
D
R
DGTI
N
L
----------
S
E
F
-----------
Q
H
V
I
S
R
S
P
D
F
A
S
-------
S
F
K
23
Fugue
47.25
11%
86
- C3 -
-
5A7Z
-
TRM10_SULAC
A:
[-4-246]
--------------MHTLAKVFS
Q
K
L
R
E
L
G
I
S
S
--------
I
Y
I
G
----
H
E
R
P
S
L
Q
S
L
A
---
I
M
K
L
----
L
K
-
N
-----------
Y
G
L
V
E
E
R
R
E
M
G
LITQDHGIKLISGKG
T
E
T
S
--
R
--------
Y
-
T
F
R
K
G
----
G
K
K
V
S
-
I
H
L
P
E
Y
P
M
K
V
I
D
L
G
L
F
E
F
L
---
N
E
E
-
E
K
E
-
K
T
L
L
--------------
Q
-
V
D
L
C
L
S
V
I
R
K
F
L
W
D
G
N
L
T
--
V
V
G
K
A
-
D
Y
--
V
L
G
R
A
N
I
--
V
Q
--------
S
L
S
L
S
DEDNP
V
I
L
D
P
Y
G
D
V
------------
V
A
T
D
Q
---------
I
L
R
D
HNVF
V
I
-----------
G
-
G
-
I
V
D
-------
K
G
R
R
L
-
D
-
R
A
T
E
R
L
A
---------
L
-
S
R
GYSFP
R
V
K
-
I
Q
L
R
G
----
S
I
----------
I
G
V
-----------
P
D
E
I
N
K
I
L
E
I
I
L
-------
R
V
K
29
Fugue
46.76
10%
64
* C5 *
-
2BU3
1
?
A:
[40-250]
-------------------------
L
S
P
N
L
I
G
F
--------
N
S
N
E
----
G
E
K
L
L
L
T
S
R
S
RED
F
-
F
P
----
L
S
M
Q
-----------
F
V
T
Q
V
N
Q
A
Y
-
C
---------------
G
V
A
S
--
I
--------
I
M
V
L
N
S
L
----
G
I
N
A
Y
-
R
V
F
T
Q
D
N
-
F
F
S
T
K
A
V
I
A
P
E
---
V
V
A
-
R
Q
G
M
T
L
D
E
--------------
L
G
R
L
I
A
S
Y
G
V
K
V
K
V
N
H
A
S
D
T
--
N
I
E
D
F
-
R
K
--
Q
V
A
E
N
L
K
--
Q
D
--------
G
N
F
V
I
-----
V
N
Y
L
R
K
E
I
G
------------
Q
E
R
G
G
---------
H
I
S
P
----
L
A
-----------
A
-
Y
-
N
E
Q
-------
T
D
R
F
L
-
I
M
D
V
S
R
Y
K
Y
---------
P
-
P
V
-----
W
V
K
-
T
T
D
L
W
----
K
A
M---------
N
T
V
-----------
D
S
V
S
Q
K
T
R
G
F
V
F
-------
V
S
K
25
Fugue
46.13
9%
79
- C1 -
-
2BON
-
YEGS_ECOLI
A:
[30-326]
PASLLILNGKSTDNLPLREAIML
L
R
E
E
G
M
T
I
H
V
--------
R
V
T
W
EKGD
A
A
R
Y
V
E
E
A
R
K
---
F
-
G
V
ATVI
A
G
-
G
-----------
G
D
G
T
I
N
E
V
S
-
T
---------------
A
L
I
Q
--
C
EGDDIPAL
G
-
I
L
P
L
G
TAND
F
A
T
S
V
-
G
I
P
E
A
L
D
-
K
A
L
K
L
A
I
A
G
D
A
---
I
A
I
-
D
M
A
-
Q
V
N
K
QTCFINMAT-----
G
G
F
G
T
R
I
A
L
G
S
V
S
Y
I
I
H
G
L
M
--
R
M
D
T
L
-
Q
P
--
D
R
C
E
I
R
G
EN
F
H
--------
W
Q
G
D
A
-----
L
V
I
G
I
G
N
G
R
QAGGGQQLCPNA
L
I
N
D
G
---------
L
L
Q
L
----
R
I
FTGDEILPALV
S
-
T
-
L
K
S
DEDNPNI
I
E
G
A
S
-
S
-
W
F
D
I
Q
A
P
---------
H
-
D
I
-----
T
F
N
-
L
D
G
E
P
----
L
S
----------
G
-
Q
-----------
N
F
H
I
E
I
L
P
A
A
L
R
-------
C
R
L
32
Fugue
40.40
24%
-4
* C3 *
-
1BW5
-
A:
[1-66]
------------------------
M
K
T
T
R
V
R
T
V
--------
L
N
E
K
----
Q
L
H
T
L
R
T
C
Y
A
---
A
-
N
P
-----------------------------------------------
R
P
--
D
--------
A
-
L
M
K
E
Q
----
L
V
E
M
T
-
G
L
S
P
R
V
I
-
R
V
W
F
Q
N
K
R
C
K
D
---
K
K
R
-
S
I
M
-
M
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
Fugue
38.87
23%
-85
- C6 -
-
3J2P
-
?
B:
[1-72]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
V
A
L
V
P
H
V
G
M
G
L
E
T
A
T
E
-----
T
W
-
M
S
--
S
E
G
A
W
K
H
--
A
Q
--------
R
I
E
T
W
-----
I
L
R
H
------------------
P
G
F
T
---------
I
M
A
A
----
I
L
-----------
A
-
Y
-
T
I
G
-------
T
T
H
F
Q
-
R
-
A
L
I
F
I
L
L
---------
T
-
A
V
-----
A
P
-----------------------------------------------------------
6
PsiBlast_PDB
36.89
30%
-35
- C6 -
-
1XVJ
-
PRVA_RAT
A:
[46-94]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
F
H
I
L
D
K
D
------------
K
S
G
F
I
---------
E
E
D
E
----
L
G
-----------
S
-
I
-
L
K
G
-------
F
S
S
D
A
-
R
-
D
L
S
A
K
E
T
---------
K
-
T
L
-----
M
A
A
-
G
D
K
D
G
----
S
-----------------------------------------------
3
PsiBlast_PDB
35.75
48%
-130
- C6 -
-
4Q7A
-
?
A:
[231-263]
---------------------------------------------------------------------------------------------------------------
G
L
Y
G
--
E
--------
A
-
V
A
R
I
G
----
L
R
L
P
P
-
A
L
S
P
E
E
A
-
I
A
V
A
T
S
L
A
S
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
32.72
45%
-292
- C6 -
-
4J8D
-
F10A1_RAT
A:
[222-241]
-----------------------------------------------------------------------------------------------------------------------------------------------
E
V
Q
P
R
A
Q
-
K
I
A
E
H
R
R
K
Y
E
R
---
K
R
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
32.08
30%
36
- C6 -
-
2WQD
-
PT1_STAAU
A:
[216-265]
-----------------------------------------------------------------------------------------------------------------
Q
G
--
D
--------
M
-
I
I
V
D
G
----
L
N
G
D
V
-
I
V
N
P
T
E
D
-
E
L
I
A
Y
Q
D
K
R
E
R
YFA
D
K
K
-
E
L
Q
-
K
L
R
D
--------------
A
D
T
V
T
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
31.87
40%
210
- C6 -
-
2PGE
-
?
A:
[40-92]
--------------------------------------------------------------------------------------------
D
G
-
H
---------------
G
G
Q
G
--
E
--------
V
-
S
L
I
P
G
----
L
S
L
D
P
E
E
Q
I
G
R
E
L
-
D
L
L
A
R
R
L
R
A
E
E
---
P
I
R
-
L
R
Q
-
F
L
A
E
--------------
R
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
Fugue
31.22
16%
27
- C2 -
-
2LV2
-
A:
[1-85]
-----------------------------------------------------------------------
M
-
G
-----------
H
H
H
H
H
H
S
H
M
-
G
---------------
D
G
E
G
--
A
--------
G
-
V
L
G
L
S
----
A
S
A
E
C
-
H
L
C
P
V
C
G
-
E
S
F
A
S
K
G
A
Q
E
R
---
H
L
R
-
L
L
H
-
A
-
A
Q
--------------
V
F
P
C
K
Y
C
P
A
T
F
Y
S
S
P
G
L
T
R
H
--
I
N
K
C
H
-
P
S
--
E
N
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
Fugue
30.72
21%
-135
- C- -
-
3H8K
-
?
B:
[573-600]
------------------------------------------------------------------------------------------------------------------------------------------------
W
S
A
D
E
R
-
Q
R
M
L
V
Q
R
K
D
E
L
---
L
Q
Q
-
A
R
K
-
R
F
L
N
--------------
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
HHSearch
27.82
20%
-276
- C6 -
-
3CP5
1
?
A:
[104-123]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
L
S
E
E
---------
Q
A
R
A
----
I
L
-----------
E
-
Y
-
L
R
Q
-------
V
A
E
N
------------------------------------------------------------------------------------------