@TOME V3
(Feb 2022)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
3D Alignment Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
3D Alignment Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
PDB Ligands
Affinity Score
Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
Sequence Alignment
Tab of Complexes
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : H12_HUMAN: (2020-02-01 )
MSETAPAAPAAAPPAEKAPVKKKAAKKAGGTPRKASGPPVSELITKAVAASKERSGVSLAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKKAKVAKPKKAAKSAAKAVKPKAAKPKVVKPKKAAPKKK
Atome Classification :
(20 SA)
-------------.........10........20----........30........40.-----.......50...---------.....60..-.....---.-70.---.----.-..---...80------------.........90........100.......110..-.....120.......-----.130.......140.......150.......160.......170.......180.......190.......200.......210.
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
-------------MSETAPAAPAAAPPAEKAP
V
K
----
K
K
A
A
KKAGGTPRKASGP
P
V
S
E
-----
L
I
T
K
A
V
AASKER---------SG
V
S
L
A
A
L
K
-
K
A
L
A
A---A-GYD---V----E-KN---N
S
R
I
-------------
K
L
G
L
K
S
LVSKG
T
L
V
Q
TKGTGASG
S
F
K
L
NKKAASG-EAKPKVK-KAGGTKP-----KKPVGAAKKPKKAAGGATPKKSAKKT
P
K
KAKKP
A
A
A
T
V
T
K
K
V
AKSPKKAKVAK
P
K
K
A
A
K
S
A
A
K
AVKPKAAKPKVVKPKKAAPKKK
23
HHSearch
65.33
87%
-84
- C4 -
-
1GHC
-
H11L_CHICK
A:
[1-75]
---------------------------------------------------
M
A
G
P
S
V
T
E
-----
L
I
T
K
A
V
S
A
S
K
E
R
---------
K
G
L
S
L
A
A
L
K
-
K
A
L
A
A
---
G
-
G
Y
D
---
V
----
E
-
K
N
---
N
S
R
I
-------------
K
L
G
L
K
S
L
V
S
K
G
T
L
V
Q
T
K
G
T
G
A
S
G
S
F
R
L
S
K
---------------------------------------------------------------------------------------------------------------
44
Fugue
64.84
17%
111
- C2 -
-
5J9T
-
EPL1_YEAST
C:
[8-279]
MTWNEYDKFYTGS
F
Q
E
T
T
S
Y
I
K
F
S
A
T
V
E
D
C
C
G
T
N
YNMD
E
R
D
E
T
F
L
N
E
Q
V
N
K
G
S
S
D
I
L
T
E
DEFEI
L
C
S
S
F
E
H
A
I
H
E
R
QPFLSMDPE
S
I
L
S
F
E
E
L
K
-
P
T
L
I
K
SDM
A
-
D
F
N
---
L
----
R
-
N
Q
---
L
N
H
E
INSHKTHFITQFD
P
V
S
Q
M
N
T
R
P
L
I
Q
L
I
E
K
F
G
S
K
I
Y
D
Y
W
R
E
R
K
I
E
V
N
G
Y
E
I
F
P
Q
L
K
F
E
R
P
G
I
D
P
YVCFR
R
R
E
V
R
H
P
R
K
T
R
R
I
D
I
L
N
S
Q
R
L
R
A
L
H
Q
E
L
K
N
A
K
D
L
A
L
L
V
A
K
R
E
N
V
S
L
N
W
I
N
D
E
L
K
I
F
D
Q
R
V
K
I
K
N
L
K
R
S
L
N
I
S
G
E
D
D
D
L
I
N
H
K
R
K
R
1
PsiBlast_PDB
64.56
89%
-92
- C4 -
-
1GHC
-
H11L_CHICK
A:
[3-75]
-----------------------------------------------------
G
P
S
V
T
E
-----
L
I
T
K
A
V
S
A
S
K
E
R
---------
K
G
L
S
L
A
A
L
K
-
K
A
L
A
A
---
G
-
G
Y
D
---
V
----
E
-
K
N
---
N
S
R
I
-------------
K
L
G
L
K
S
L
V
S
K
G
T
L
V
Q
T
K
G
T
G
A
S
G
S
F
R
L
S
K
---------------------------------------------------------------------------------------------------------------
25
HHSearch
56.45
45%
-1
- C4 -
-
5WCU
-
H5_CHICK
V:
[2-76]
---------------------------------------------------
A
S
H
P
T
Y
S
E
-----
M
I
A
A
A
I
R
A
E
K
S
R
---------
G
G
S
S
R
Q
S
I
Q
-
K
Y
I
K
S
-----
H
Y
K
---
V
----
G
H
N
A
---
D
L
Q
I
-------------
K
L
S
I
R
R
L
L
A
A
G
V
L
K
Q
T
K
G
V
G
A
S
G
S
F
R
L
A
K
---------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
54.71
44%
-3
- C4 -
-
4QLC
-
H5_CHICK
U:
[2-74]
---------------------------------------------------
A
S
H
P
T
Y
S
E
-----
M
I
A
A
A
I
R
A
E
K
S
R
---------
G
G
S
S
R
Q
S
I
Q
-
K
Y
I
K
S
---
H
--
Y
K
---
V
----
G
-
H
N
A--
D
L
Q
I
-------------
K
L
S
I
R
R
L
L
A
A
G
V
L
K
Q
T
K
G
V
G
A
S
G
S
F
R
L
-----------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
54.55
43%
-23
- C4 -
-
1HST
-
H5_CHICK
A:
[24-95]
----------------------------------------------------
S
H
P
T
Y
S
E
-----
M
I
A
A
A
I
R
A
E
K
S
R
---------
G
G
S
S
R
Q
S
I
Q
-
K
Y
I
K
S
---
H
--
Y
K
---
V
----
G
-
H
N
A--
D
L
Q
I
-------------
K
L
S
I
R
R
L
L
A
A
G
V
L
K
Q
T
K
G
V
G
A
S
G
S
F
R
L
-----------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
54.53
44%
-7
- C4 -
-
5WCU
-
H5_CHICK
U:
[2-74]
---------------------------------------------------
A
S
H
P
T
Y
S
E
-----
M
I
A
A
A
I
R
A
E
K
S
R
---------
G
G
S
S
R
Q
S
I
Q
-
K
Y
I
K
S
---
H
--
Y
K
---
V
----
G
-
H
N
A--
D
L
Q
I
-------------
K
L
S
I
R
R
L
L
A
A
G
V
L
K
Q
T
K
G
V
G
A
S
G
S
F
R
L
-----------------------------------------------------------------------------------------------------------------
27
HHSearch
54.40
41%
-9
- C4 -
-
1HST
-
H5_CHICK
B:
[24-97]
----------------------------------------------------
S
H
P
T
Y
S
E
-----
M
I
A
A
A
I
R
A
E
K
S
R
---------
G
G
S
S
R
Q
S
I
Q
-
K
Y
I
K
S
-----
H
Y
K
---
V
----
G
H
N
A
---
D
L
Q
I
-------------
K
L
S
I
R
R
L
L
A
A
G
V
L
K
Q
T
K
G
V
G
A
S
G
S
F
R
L
A
K
---------------------------------------------------------------------------------------------------------------
24
HHSearch
54.31
35%
23
- C4 -
-
2LSO
-
H1X_HUMAN
A:
[3-82]
---------------------------------------------------
M
Q
P
G
K
Y
S
Q
-----
L
V
V
E
T
I
R
R
L
G
E
R
---------
N
G
S
S
L
A
K
I
Y
-
T
E
A
K
K
---
V
P
W
F
D
---
Q
----
Q
-
N
G
---
R
T
Y
L
-------------
K
Y
S
I
K
A
L
V
Q
N
D
T
L
L
Q
V
K
G
T
G
A
N
G
S
F
K
L
N
R
K
K
L
E
-----------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
51.82
42%
-6
- C4 -
-
5NL0
-
H10B_XENLA
Z:
[25-95]
-----------------------------------------------
H
P
K
------
Y
S
D
-----
M
I
L
A
A
V
Q
A
E
K
S
R
---------
S
G
S
S
R
Q
S
I
Q
-
K
Y
I
K
N
---
H
--
Y
K
---
V
----
G
-
E
N
A--
D
S
Q
I
-------------
K
L
S
I
K
R
L
V
T
S
G
A
L
K
Q
T
K
G
V
G
A
S
G
S
F
R
L
-----------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
51.59
39%
25
- C4 -
-
2LSO
-
H1X_HUMAN
A:
[8-83]
--------------------------------------------------------
Y
S
Q
-----
L
V
V
E
T
I
R
R
L
G
E
R
---------
N
G
S
S
L
A
K
I
Y
T
E
A
K
K
V
---
P
-
W
F
D
---
Q
----
Q
-
N
G
---
R
T
Y
L
-------------
K
Y
S
I
K
A
L
V
Q
N
D
T
L
L
Q
V
K
G
T
G
A
N
G
S
F
K
L
N
R
K
K
L
E
G
----------------------------------------------------------------------------------------------------------
21
HHSearch
51.48
43%
6
- C4 -
-
5NL0
-
H10B_XENLA
Z:
[25-97]
-----------------------------------------------------
H
P
K
Y
S
D
-----
M
I
L
A
A
V
Q
A
E
K
S
R
---------
S
G
S
S
R
Q
S
I
Q
-
K
Y
I
K
N
-----
H
Y
K
---
V
----
G
E
N
A
---
D
S
Q
I
-------------
K
L
S
I
K
R
L
V
T
S
G
A
L
K
Q
T
K
G
V
G
A
S
G
S
F
R
L
A
K
---------------------------------------------------------------------------------------------------------------
22
HHSearch
50.70
38%
20
- C4 -
-
6N88
-
?
C:
[24-97]
----------------------------------------------------
D
H
P
K
Y
S
D
-----
M
I
V
A
A
I
Q
A
E
K
N
R
---------
A
G
S
S
R
Q
S
I
Q
-
K
Y
I
K
S
-----
H
Y
K
---
V
----
G
E
N
A
---
D
S
Q
I
-------------
K
L
S
I
K
R
L
V
T
T
G
V
L
K
Q
T
K
G
V
G
A
S
G
S
F
R
L
A
K
---------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
50.14
38%
14
- C4 -
-
6N88
-
?
C:
[24-95]
----------------------------------------------------
D
H
P
K
Y
S
D
-----
M
I
V
A
A
I
Q
A
E
K
N
R
---------
A
G
S
S
R
Q
S
I
Q
-
K
Y
I
K
S
-----
H
Y
K
---
V
----
G
-
E
N
A--
D
S
Q
I
-------------
K
L
S
I
K
R
L
V
T
T
G
V
L
K
Q
T
K
G
V
G
A
S
G
S
F
R
L
-----------------------------------------------------------------------------------------------------------------
26
HHSearch
48.27
31%
-27
- C4 -
-
2RQP
-
HP1B3_HUMAN
A:
[153-235]
------------------------------------------------
M
A
S
S
P
R
P
K
M
D
A
-----
I
L
T
E
A
I
K
A
C
F
Q
K
---------
S
G
A
S
V
V
A
I
R
-
K
Y
I
I
H
-----
K
Y
P
SLE
L
----
E
-
R
R
---
G
Y
L
L
-------------
K
Q
A
L
K
R
E
L
N
R
G
V
I
K
Q
V
K
G
K
G
A
S
G
S
F
V
V
V
Q
K
S
R
------------------------------------------------------------------------------------------------------------
53
Fugue
47.70
13%
-74
- C4 -
-
2FOK
-
T2F1_PLAOK
A:
[287-386]
--------------------------------
V
P
----
K
R
V
Y
W
E
M
L
A
T
N
L
T
-
D
K
E
Y
V
R
T
-----
R
R
A
L
I
L
E
I
L
I
K
A
---------
G
S
L
K
I
E
Q
I
Q
-
D
N
L
K
K
---
L
-
G
F
D
----------
E
V
---
I
E
T
I
-------------
E
N
D
I
K
G
L
I
N
T
G
I
F
I
E
I
K
G
R
F
Y
Q
L
K
D
H
I
L
Q
F
V
I
P
N
-
R
L
V
------------------------------------------------------------------------------------------------------
29
HHSearch
47.32
36%
41
- C4 -
-
1UHM
-
H1_YEAST
A:
[42-117]
---------------------------------------------------
A
S
S
K
S
Y
R
E
-----
L
I
I
E
G
L
T
A
L
K
E
R
---------
K
G
S
S
R
P
A
L
K
-
K
F
I
K
E
-----
N
Y
P
---
I
VGSA
S
-
N
F
---
D
L
Y
F
-------------
N
N
A
I
K
K
G
V
E
A
G
D
F
E
Q
P
K
G
--
P
A
G
A
V
K
L
A
K
---------------------------------------------------------------------------------------------------------------
28
HHSearch
47.30
32%
51
- C4 -
-
1YQA
-
H1_YEAST
A:
[172-254]
------------------------------------------------
A
S
S
P
S
S
L
T
Y
K
E
-----
M
I
L
K
S
M
P
Q
L
N
D
G
---------
K
G
S
S
R
I
V
L
K
-
K
Y
V
K
D
-----
T
Y
P
---
I
VGSA
S
-
N
F
---
D
Y
L
F
-------------
N
S
A
I
K
K
C
V
E
N
G
E
L
V
Q
P
K
--
G
P
S
G
I
I
K
L
N
K
K
K
V
K
-----------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
47.25
38%
21
- C4 -
-
6N89
-
?
B:
[24-95]
----------------------------------------------------
D
H
P
K
Y
S
D
-----
M
I
V
A
A
I
Q
A
E
K
N
R
---------
A
G
S
S
R
Q
S
I
Q
-
K
Y
I
K
S
-----
H
Y
K
---
V
----
G
-
E
N
A--
D
S
Q
I
-------------
K
L
S
I
K
R
L
V
T
T
G
V
L
K
Q
T
K
G
V
G
A
S
G
S
F
R
L
-----------------------------------------------------------------------------------------------------------------
43
Fugue
46.21
29%
61
- C4 -
-
1YQA
-
H1_YEAST
A:
[171-257]
-----------------------------------------------
K
A
S
S
P
S
S
L
T
Y
K
E
-----
M
I
L
K
S
M
P
Q
L
N
D
G
---------
K
G
S
S
R
I
V
L
K
-
K
Y
V
K
D
---
T
-
Y
P
I
---
V
----
G
-
S
A
SNF
D
Y
L
F
-------------
N
S
A
I
K
K
C
V
E
N
G
E
L
V
Q
P
K
G
--
P
S
G
I
I
K
L
N
K
K
K
V
K
L
-
S
T
-------------------------------------------------------------------------------------------------------