@TOME V3
(Feb 2022)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
3D Alignment Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
3D Alignment Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
PDB Ligands
Affinity Score
Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
Sequence Alignment
Tab of Complexes
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PSB10_HUMAN: (2020-02-02 )
MLKPALEPRGGFSFENCQRNASLERVLPGLKVPHARKTGTTIAGLVFQDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADAEMTTRMVASKMELHALSTGREPRVATVTRILRQTLFRYQGHVGASLIVGGVDLTGPQLYGVHPHGSYSRLPFTALGSGQDAALAVLEDRFQPNMTLEAAQGLLVEAVTAGILGDLGSGGNVDACVITKTGAKLLRTLSSPTEPVKRSGRYHFVPGTTAVLTQTVKPLTLELVEETVQAMEVE
Atome Classification :
(20 SA)
.........10........20.......--.30........40........50........60........70........80........90........100.....-..110-----.......120.......130-.-........140....----...150.......160........170.......180-........190.......200.......210.......-220........230.......240.......250.......260.......270.
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MLKPALEPRGGF
S
F
E
N
C
QRNA
S
L
E
R
VLP--GLKVPHARKTG
T
T
I
A
G
L
V
FQD
G
V
I
L
GADTRATNDSVVADKSC
E
K
I
H
F
IA
P
K
I
Y
CCGAGVAA
D
A
E
M
T
T
R
M
V
A
S
K
M
E
L
H
A
L-STGRE-----P
R
V
A
T
V
T
R
I
L
R
Q
T
L
F
R
YQ---G-HVG
A
S
L
I
VGGVDLTG----P
Q
L
Y
G
VHPHGSYSR-L
P
F
T
ALGSG
Q
D
A
A
L
A
V
L
E
D
RF--QPNM
T
L
E
A
A
Q
G
L
L
V
E
A
V
T
A
G
I
L
GDLGSGGNV
D
A
C
V
I
TK-
T
G
-
A
K
L
L
R
T
LSSPT
E
P
V
KRSG
R
Y
H
FVPG
T
T
A
V
L
T
QTVK
P
L
T
L
E
L
V
E
E
T
V
Q
A
MEVE
1
PsiBlast_PDB
100.00
100%
0
- C- -
-
6AVO
-
PSB10_HUMAN
B:
[1-219]
-----------------------------------------
T
T
I
A
G
L
V
F
Q
D
G
V
I
L
G
A
D
T
R
A
T
N
D
S
V
V
A
D
K
S
C
E
K
I
H
F
I
A
P
K
I
Y
C
C
G
A
G
V
A
A
D
A
E
M
T
T
R
M
V
A
S
K
M
E
L
H
A
L
-
S
T
G
R
E
-----
P
R
V
A
T
V
T
R
I
L
R
Q
T
L
F
R
Y
Q
---
G
-
H
V
G
A
S
L
I
V
G
G
V
D
L
T
G
----
P
Q
L
Y
G
V
H
P
H
G
S
Y
S
R
-
L
P
F
T
A
L
G
S
G
Q
D
A
A
L
A
V
L
E
D
R
F
--
Q
P
N
M
T
L
E
A
A
Q
G
L
L
V
E
A
V
T
A
G
I
L
G
D
L
G
S
G
G
N
V
D
A
C
V
I
T
K
-
T
G
-
A
K
L
L
R
T
L
S
S
P
T
E
P
V
K
R
S
G
R
Y
H
F
V
P
G
T
T
A
V
L
T
Q
T
V
K
P
L
---------------
22
HHSearch
93.58
89%
0
- C- -
-
3UNF
-
PSB10_MOUSE
V:
[1-219]
-----------------------------------------
T
T
I
A
G
L
V
F
R
D
G
V
I
L
G
A
D
T
R
A
T
N
D
S
V
V
A
D
K
S
C
E
K
I
H
F
I
A
P
K
I
Y
C
C
G
A
G
V
A
A
D
T
E
M
T
T
R
M
A
A
S
K
M
E
L
H
A
L
-
S
T
G
R
E
-----
P
R
V
A
T
V
T
R
I
L
R
Q
T
L
F
R
Y
Q
---
G
-
H
V
G
A
S
L
V
V
G
G
V
D
L
N
G
----
P
Q
L
Y
E
V
H
P
H
G
S
Y
S
R
-
L
P
F
T
A
L
G
S
G
Q
G
A
A
V
A
L
L
E
D
R
F
--
Q
P
N
M
T
L
E
A
A
Q
E
L
L
V
E
A
I
T
A
G
I
L
S
D
L
G
S
G
G
N
V
D
A
C
V
I
T
A
-
G
G
-
A
K
L
Q
R
A
L
S
T
P
T
E
P
V
Q
R
A
G
R
Y
R
F
A
P
G
T
T
P
V
L
T
R
E
V
R
P
L
---------------
21
HHSearch
93.58
89%
0
- C- -
-
3UNH
-
PSB10_MOUSE
H:
[1-219]
-----------------------------------------
T
T
I
A
G
L
V
F
R
D
G
V
I
L
G
A
D
T
R
A
T
N
D
S
V
V
A
D
K
S
C
E
K
I
H
F
I
A
P
K
I
Y
C
C
G
A
G
V
A
A
D
T
E
M
T
T
R
M
A
A
S
K
M
E
L
H
A
L
-
S
T
G
R
E
-----
P
R
V
A
T
V
T
R
I
L
R
Q
T
L
F
R
Y
Q
---
G
-
H
V
G
A
S
L
V
V
G
G
V
D
L
N
G
----
P
Q
L
Y
E
V
H
P
H
G
S
Y
S
R
-
L
P
F
T
A
L
G
S
G
Q
G
A
A
V
A
L
L
E
D
R
F
--
Q
P
N
M
T
L
E
A
A
Q
E
L
L
V
E
A
I
T
A
G
I
L
S
D
L
G
S
G
G
N
V
D
A
C
V
I
T
A
-
G
G
-
A
K
L
Q
R
A
L
S
T
P
T
E
P
V
Q
R
A
G
R
Y
R
F
A
P
G
T
T
P
V
L
T
R
E
V
R
P
L
---------------
3
PsiBlast_PDB
93.06
88%
0
- C- -
-
3UNH
-
PSB10_MOUSE
H:
[1-219]
-----------------------------------------
T
T
I
A
G
L
V
F
R
D
G
V
I
L
G
A
D
T
R
A
T
N
D
S
V
V
A
D
K
S
C
E
K
I
H
F
I
A
P
K
I
Y
C
C
G
A
G
V
A
A
D
T
E
M
T
T
R
M
A
A
S
K
M
E
L
H
A
L
-
S
T
G
R
E
-----
P
R
V
A
T
V
T
R
I
L
R
Q
T
L
F
R
Y
Q
---
G
-
H
V
G
A
S
L
V
V
G
G
V
D
L
N
G
----
P
Q
L
Y
E
V
H
P
H
G
S
Y
S
R
-
L
P
F
T
A
L
G
S
G
Q
G
A
A
V
A
L
L
E
D
R
F
--
Q
P
N
M
T
L
E
A
A
Q
E
L
L
V
E
A
I
T
A
G
I
L
S
D
L
G
S
G
G
N
V
D
A
C
V
I
T
A
-
G
G
-
A
K
L
Q
R
A
L
S
T
P
T
E
P
V
Q
R
A
G
R
Y
R
F
A
P
G
T
T
P
V
L
T
R
E
V
R
P
L
---------------
2
PsiBlast_PDB
93.06
88%
0
- C- -
-
3UNF
-
PSB10_MOUSE
H:
[1-219]
-----------------------------------------
T
T
I
A
G
L
V
F
R
D
G
V
I
L
G
A
D
T
R
A
T
N
D
S
V
V
A
D
K
S
C
E
K
I
H
F
I
A
P
K
I
Y
C
C
G
A
G
V
A
A
D
T
E
M
T
T
R
M
A
A
S
K
M
E
L
H
A
L
-
S
T
G
R
E
-----
P
R
V
A
T
V
T
R
I
L
R
Q
T
L
F
R
Y
Q
---
G
-
H
V
G
A
S
L
V
V
G
G
V
D
L
N
G
----
P
Q
L
Y
E
V
H
P
H
G
S
Y
S
R
-
L
P
F
T
A
L
G
S
G
Q
G
A
A
V
A
L
L
E
D
R
F
--
Q
P
N
M
T
L
E
A
A
Q
E
L
L
V
E
A
I
T
A
G
I
L
S
D
L
G
S
G
G
N
V
D
A
C
V
I
T
A
-
G
G
-
A
K
L
Q
R
A
L
S
T
P
T
E
P
V
Q
R
A
G
R
Y
R
F
A
P
G
T
T
P
V
L
T
R
E
V
R
P
L
---------------
9
PsiBlast_PDB
88.61
58%
-122
- C4 -
-
5M32
-
PSB7_HUMAN
H:
[1-221]
-----------------------------------------
T
T
I
A
G
V
V
Y
K
D
G
I
V
L
G
A
D
T
R
A
T
E
G
M
V
V
A
D
K
N
C
S
K
I
H
F
I
S
P
N
I
Y
C
C
G
A
G
T
A
A
D
T
D
M
T
T
Q
L
I
S
S
N
L
E
L
H
S
L
-
S
T
G
R
L
-----
P
R
V
V
T
A
N
R
M
L
K
Q
M
L
F
R
Y
Q
---
G
-
Y
I
G
A
A
L
V
L
G
G
V
D
V
T
G
----
P
H
L
Y
S
I
Y
P
H
G
S
T
D
K
-
L
P
Y
V
T
M
G
S
G
S
L
A
A
M
A
V
F
E
D
K
F
--
R
P
D
M
E
E
E
E
A
K
N
L
V
S
E
A
I
A
A
G
I
F
N
D
L
G
S
G
S
N
I
D
L
C
V
I
S
K
-
N
K
-
L
D
F
L
R
P
Y
T
V
P
N
K
K
G
T
R
L
G
R
Y
R
C
E
K
G
T
T
A
V
L
T
E
K
I
T
P
L
E
I
-------------
10
PsiBlast_PDB
79.39
58%
0
- C- -
-
5L4G
-
8:
[A3-M43]
-------
P
V
G
G
F
S
F
D
N
C
R
R
N
A
V
L
E
A
D
F
A
KR
G
Y
K
L
P
K
V
R
K
T
G
T
T
I
A
G
V
V
Y
K
D
G
I
V
L
G
A
D
T
R
A
T
E
G
M
V
V
-
D
K
N
C
S
K
I
H
F
I
S
P
N
I
Y
C
C
G
A
G
T
A
A
D
T
D
M
T
T
Q
L
I
S
S
N
L
E
L
H
S
L
-
S
T
G
R
L
-----
P
R
V
V
T
A
N
R
M
L
K
Q
M
L
F
R
Y
Q
---
G
-
Y
I
G
A
A
L
V
L
G
G
V
D
V
T
G
----
P
H
L
Y
S
I
Y
P
H
G
S
T
D
K
-
L
P
Y
V
T
M
G
S
G
S
L
A
A
M
A
V
F
E
D
K
F
--
R
P
D
M
E
E
E
E
A
K
N
L
V
S
E
A
I
A
A
G
I
F
N
D
L
---------------------
R
P
Y
T
V
P
N
K
K
G
-
R
L
G
R
Y
------
T
A
V
L
T
E
K
I
T
P
L
E
I
E
V
L
E
E
T
V
Q
T
M
D
--
23
HHSearch
73.83
58%
0
- C- -
-
5LE5
-
PSB7_HUMAN
H:
[1-220]
-----------------------------------------
T
T
I
A
G
V
V
Y
K
D
G
I
V
L
G
A
D
T
R
A
T
E
G
M
V
V
A
D
K
N
C
S
K
I
H
F
I
S
P
N
I
Y
C
C
G
A
G
T
A
A
D
T
D
M
T
T
Q
L
I
S
S
N
L
E
L
H
S
L
-
S
T
G
R
L
-----
P
R
V
V
T
A
N
R
M
L
K
Q
M
L
F
R
Y
Q
---
G
-
Y
I
G
A
A
L
V
L
G
G
V
D
V
T
G
----
P
H
L
Y
S
I
Y
P
H
G
S
T
D
K
-
L
P
Y
V
T
M
G
S
G
S
L
A
A
M
A
V
F
E
D
K
F
--
R
P
D
M
E
E
E
E
A
K
N
L
V
S
E
A
I
A
A
G
I
F
N
D
L
G
S
G
S
N
I
D
L
C
V
I
S
K
-
N
K
-
L
D
F
L
R
P
Y
T
V
P
N
K
K
G
T
R
L
G
R
Y
R
C
E
K
G
T
T
A
V
L
T
E
K
I
T
P
L
E
--------------
20
PsiBlast_PDB
73.48
58%
0
- C- -
-
6HUB
-
?
H:
[1-219]
-----------------------------------------
T
T
I
A
G
V
V
Y
K
D
G
I
V
L
G
A
D
T
R
A
T
E
G
M
V
V
A
D
K
N
C
S
K
I
H
F
I
S
P
N
I
Y
C
C
G
A
G
T
A
A
D
T
D
M
T
T
Q
L
I
S
S
N
L
E
L
H
S
L
-
S
T
G
R
L
-----
P
R
V
V
T
A
N
R
M
L
K
Q
M
L
F
R
Y
Q
---
G
-
Y
I
G
A
A
L
V
L
G
G
V
D
V
T
G
----
P
H
L
Y
S
I
Y
P
H
G
S
T
D
K
-
L
P
Y
V
T
M
G
S
G
S
L
A
A
M
A
V
F
E
D
K
F
--
R
P
D
M
E
E
E
E
A
K
N
L
V
S
E
A
I
A
A
G
I
F
N
D
L
G
S
G
G
N
I
D
L
C
V
I
S
K
-
N
K
-
L
D
F
L
R
P
Y
T
V
P
N
K
K
G
T
R
L
G
R
Y
R
C
E
K
G
T
T
A
V
L
T
E
K
I
T
P
L
---------------
19
PsiBlast_PDB
73.48
58%
0
- C- -
-
6HTR
-
?
H:
[1-219]
-----------------------------------------
T
T
I
A
G
V
V
Y
K
D
G
I
V
L
G
A
D
T
R
A
T
E
G
M
V
V
A
D
K
N
C
S
K
I
H
F
I
S
P
N
I
Y
C
C
G
A
G
T
A
A
D
T
D
M
T
T
Q
L
I
S
S
N
L
E
L
H
S
L
-
S
T
G
R
L
-----
P
R
V
V
T
A
N
R
M
L
K
Q
M
L
F
R
Y
Q
---
G
-
Y
I
G
A
A
L
V
L
G
G
V
D
V
T
G
----
P
H
L
Y
S
I
Y
P
H
G
S
T
D
K
-
L
P
Y
V
T
M
G
S
G
S
L
A
A
M
A
V
F
E
D
K
F
--
R
P
D
M
E
E
E
E
A
K
N
L
V
S
E
A
I
A
A
G
I
F
N
D
L
G
S
G
G
N
I
D
L
C
V
I
S
K
-
N
K
-
L
D
F
L
R
P
Y
T
V
P
N
K
K
G
T
R
L
G
R
Y
R
C
E
K
G
T
T
A
V
L
T
E
K
I
T
P
L
---------------
18
PsiBlast_PDB
73.48
58%
0
- C- -
-
6HTP
-
?
H:
[1-219]
-----------------------------------------
T
T
I
A
G
V
V
Y
K
D
G
I
V
L
G
A
D
T
R
A
T
E
G
M
V
V
A
D
K
N
C
S
K
I
H
F
I
S
P
N
I
Y
C
C
G
A
G
T
A
A
D
T
D
M
T
T
Q
L
I
S
S
N
L
E
L
H
S
L
-
S
T
G
R
L
-----
P
R
V
V
T
A
N
R
M
L
K
Q
M
L
F
R
Y
Q
---
G
-
Y
I
G
A
A
L
V
L
G
G
V
D
V
T
G
----
P
H
L
Y
S
I
Y
P
H
G
S
T
D
K
-
L
P
Y
V
T
M
G
S
G
S
L
A
A
M
A
V
F
E
D
K
F
--
R
P
D
M
E
E
E
E
A
K
N
L
V
S
E
A
I
A
A
G
I
F
N
D
L
G
S
G
G
N
I
D
L
C
V
I
S
K
-
N
K
-
L
D
F
L
R
P
Y
T
V
P
N
K
K
G
T
R
L
G
R
Y
R
C
E
K
G
T
T
A
V
L
T
E
K
I
T
P
L
---------------
17
PsiBlast_PDB
73.48
58%
0
- C- -
-
6HTD
-
?
H:
[1-219]
-----------------------------------------
T
T
I
A
G
V
V
Y
K
D
G
I
V
L
G
A
D
T
R
A
T
E
G
M
V
V
A
D
K
N
C
S
K
I
H
F
I
S
P
N
I
Y
C
C
G
A
G
T
A
A
D
T
D
M
T
T
Q
L
I
S
S
N
L
E
L
H
S
L
-
S
T
G
R
L
-----
P
R
V
V
T
A
N
R
M
L
K
Q
M
L
F
R
Y
Q
---
G
-
Y
I
G
A
A
L
V
L
G
G
V
D
V
T
G
----
P
H
L
Y
S
I
Y
P
H
G
S
T
D
K
-
L
P
Y
V
T
M
G
S
G
S
L
A
A
M
A
V
F
E
D
K
F
--
R
P
D
M
E
E
E
E
A
K
N
L
V
S
E
A
I
A
A
G
I
F
N
D
L
G
S
G
G
N
I
D
L
C
V
I
S
K
-
N
K
-
L
D
F
L
R
P
Y
T
V
P
N
K
K
G
T
R
L
G
R
Y
R
C
E
K
G
T
T
A
V
L
T
E
K
I
T
P
L
---------------
16
PsiBlast_PDB
73.48
58%
0
- C- -
-
6HTC
-
?
H:
[1-219]
-----------------------------------------
T
T
I
A
G
V
V
Y
K
D
G
I
V
L
G
A
D
T
R
A
T
E
G
M
V
V
A
D
K
N
C
S
K
I
H
F
I
S
P
N
I
Y
C
C
G
A
G
T
A
A
D
T
D
M
T
T
Q
L
I
S
S
N
L
E
L
H
S
L
-
S
T
G
R
L
-----
P
R
V
V
T
A
N
R
M
L
K
Q
M
L
F
R
Y
Q
---
G
-
Y
I
G
A
A
L
V
L
G
G
V
D
V
T
G
----
P
H
L
Y
S
I
Y
P
H
G
S
T
D
K
-
L
P
Y
V
T
M
G
S
G
S
L
A
A
M
A
V
F
E
D
K
F
--
R
P
D
M
E
E
E
E
A
K
N
L
V
S
E
A
I
A
A
G
I
F
N
D
L
G
S
G
G
N
I
D
L
C
V
I
S
K
-
N
K
-
L
D
F
L
R
P
Y
T
V
P
N
K
K
G
T
R
L
G
R
Y
R
C
E
K
G
T
T
A
V
L
T
E
K
I
T
P
L
---------------
15
PsiBlast_PDB
73.48
58%
0
- C- -
-
6HTB
-
?
H:
[1-219]
-----------------------------------------
T
T
I
A
G
V
V
Y
K
D
G
I
V
L
G
A
D
T
R
A
T
E
G
M
V
V
A
D
K
N
C
S
K
I
H
F
I
S
P
N
I
Y
C
C
G
A
G
T
A
A
D
T
D
M
T
T
Q
L
I
S
S
N
L
E
L
H
S
L
-
S
T
G
R
L
-----
P
R
V
V
T
A
N
R
M
L
K
Q
M
L
F
R
Y
Q
---
G
-
Y
I
G
A
A
L
V
L
G
G
V
D
V
T
G
----
P
H
L
Y
S
I
Y
P
H
G
S
T
D
K
-
L
P
Y
V
T
M
G
S
G
S
L
A
A
M
A
V
F
E
D
K
F
--
R
P
D
M
E
E
E
E
A
K
N
L
V
S
E
A
I
A
A
G
I
F
N
D
L
G
S
G
G
N
I
D
L
C
V
I
S
K
-
N
K
-
L
D
F
L
R
P
Y
T
V
P
N
K
K
G
T
R
L
G
R
Y
R
C
E
K
G
T
T
A
V
L
T
E
K
I
T
P
L
---------------
35
HHSearch
69.60
27%
-78
- C4 -
-
1YAR
-
PSB_THEAC
M:
[9-196]
-----------------------------------------
T
T
T
V
G
I
T
L
K
D
A
V
I
M
A
T
E
R
R
V
T
M
E
N
F
I
M
H
K
N
G
K
K
L
F
Q
I
D
T
Y
T
G
M
T
I
A
G
L
V
G
D
A
Q
V
L
V
R
Y
M
K
A
E
L
E
L
Y
R
L
-
Q
R
R
V
N
-----
M
P
I
E
A
V
A
T
L
L
S
N
M
L
N
Q
V
K
Y--
M
-
P
Y
M
V
Q
L
L
V
G
G
I
D
T
-
A
----
P
H
V
F
S
I
D
A
A
G
G
S
V
E
-
D
I
Y
A
S
T
G
S
G
S
P
F
V
Y
G
V
L
E
S
Q
Y
--
S
E
K
M
T
V
D
E
G
V
D
L
V
I
R
A
I
S
A
A
K
Q
R
D
S
A
S
G
G
M
I
D
V
A
V
I
T
R
K
D
G
-
Y
V
Q
L
P
-----------------------------------------------
42
HHSearch
68.69
27%
-83
- C4 -
-
5VFR
-
PSB5_HUMAN
R:
[1-187]
-----------------------------------------
T
T
T
L
A
F
K
F
R
H
G
V
I
V
A
A
D
S
R
A
T
A
G
A
Y
I
A
S
Q
T
V
K
K
V
I
E
I
N
P
Y
L
L
G
T
M
A
G
G
A
A
D
C
S
F
W
E
R
L
L
A
R
Q
C
R
I
Y
E
L
-
R
N
K
E
R
-----
I
S
V
A
A
A
S
K
L
L
A
N
M
V
Y
Q
Y
K
---
G
M
G
L
S
M
G
T
M
I
C
G
W
D
K
R
G
----
P
G
L
Y
Y
V
D
S
E
G
N
R
I
S
-
G
A
T
F
S
V
G
S
G
S
V
Y
A
Y
G
V
M
D
R
G
Y
--
S
Y
D
L
E
V
E
Q
A
Y
D
L
A
R
R
A
I
Y
Q
A
T
Y
R
D
A
Y
S
G
G
A
V
N
L
Y
H
V
R
E
-
D
G
-
W
I
R
V
------------------------------------------------
24
HHSearch
67.79
48%
0
- C- -
-
5FG9
-
PSB2_YEAST
H:
[1-230]
-------------------------------------
T
S
V
G
T
T
I
V
G
V
K
F
N
N
G
V
V
I
A
A
D
T
R
S
T
Q
G
P
I
V
A
D
K
N
C
A
K
L
H
R
I
S
P
K
I
W
C
A
G
A
G
T
A
A
D
T
E
A
V
T
Q
L
I
G
S
N
I
E
L
H
S
L
-
Y
T
S
R
E
-----
P
R
V
V
S
A
L
Q
M
L
K
Q
H
L
F
K
Y
Q
---
G
-
H
I
G
A
Y
L
I
V
A
G
V
D
P
T
G
----
S
H
L
F
S
I
H
A
H
G
S
T
D
V
-
G
Y
Y
L
S
L
G
S
G
S
L
A
A
M
A
V
L
E
S
H
W
--
K
Q
D
L
T
K
E
E
A
I
K
L
A
S
D
A
I
Q
A
G
I
W
N
D
L
G
S
G
S
N
V
D
V
C
V
M
E
I
-
G
K
D
A
E
Y
L
R
N
Y
L
T
P
N
V
R
E
E
K
Q
K
S
Y
K
F
P
R
G
T
T
A
V
L
K
E
S
I
V
N
I
C
-
D
I
Q
E
E
--------
25
HHSearch
66.57
48%
0
- C- -
-
4R17
-
PSB2_YEAST
H:
[1-226]
-----------------------------------------
T
T
I
V
G
V
K
F
N
N
G
V
V
I
A
A
D
T
R
S
T
Q
G
P
I
V
A
D
K
N
C
A
K
L
H
R
I
S
P
K
I
W
C
A
G
A
G
T
A
A
D
T
E
A
V
T
Q
L
I
G
S
N
I
E
L
H
S
L
-
Y
T
S
R
E
-----
P
R
V
V
S
A
L
Q
M
L
K
Q
H
L
F
K
Y
Q
---
G
-
H
I
G
A
Y
L
I
V
A
G
V
D
P
T
G
----
S
H
L
F
S
I
H
A
H
G
S
T
D
V
-
G
Y
Y
L
S
L
G
S
G
S
L
A
A
M
A
V
L
E
S
H
W
--
K
Q
D
L
T
K
E
E
A
I
K
L
A
S
D
A
I
Q
A
G
I
W
N
D
L
G
S
G
S
N
V
D
V
C
V
M
E
I
-
G
K
D
A
E
Y
L
R
N
Y
L
T
P
N
V
R
E
E
K
Q
K
S
Y
K
F
P
R
G
T
T
A
V
L
K
E
S
I
V
N
I
C
-
D
I
Q
E
E
--------
33
HHSearch
65.46
19%
-40
- C4 -
-
5VFR
-
PSB4_HUMAN
T:
[3-210]
-----------------------------------
N
P
M
V
T
G
T
S
V
L
G
V
K
F
E
G
G
V
V
I
A
A
D
M
L
G
S
Y
G
S
L
A
R
F
R
N
I
S
R
I
M
R
V
N
N
S
T
M
L
G
A
S
G
D
Y
A
D
F
Q
Y
L
K
Q
V
L
G
Q
M
V
I
D
E
E
L
L
G
D
G
H
S
-----
Y
S
P
R
A
I
H
S
W
L
T
R
A
M
Y
S
R
R
SKM
N
-
P
L
W
N
T
M
V
I
G
G
Y
A
D
G
E
----
S
F
L
G
Y
V
D
M
L
G
V
A
Y
E
-
A
P
S
L
A
T
G
Y
G
A
Y
L
A
Q
P
L
L
R
E
V
L
EK
Q
P
V
L
S
Q
T
E
A
R
D
L
V
E
R
C
M
R
V
L
Y
Y
R
D
A
R
S
Y
N
R
F
Q
I
A
T
V
T
E
-
K
G
-
V
E
I
E
G
P
L
S
T
E
T
N
W
D
--------------------------------------
48
Fugue
64.90
19%
-52
- C4 -
-
1Q5Q
-
PSA1_RHOER
A:
[9-235]
-
A
E
Q
I
M
R
D
R
S
E
L
A
R
K
G
I
A
R
---------------------
G
R
S
V
V
V
L
T
F
R
D
G
V
L
F
V
A
E
N
P
S
T
A
L
--------
H
K
V
S
E
L
Y
D
R
L
G
F
A
A
V
G
K
Y
N
E
F
E
N
L
R
R
A
G
I
V
H
A
D
M
R
G
Y
-
S
Y
D
R
R
DVTGR
S
L
A
N
A
Y
A
Q
T
L
G
T
I
F
T
E
Q
P
---
K
-
P
Y
E
V
E
I
C
V
A
E
V
G
R
V
G
SPKA
P
Q
L
Y
R
I
T
Y
D
G
S
I
V
D
E
Q
H
F
V
V
M
G
G
T
T
E
P
I
A
T
A
M
R
E
S
Y
--
R
A
D
L
D
L
E
A
A
V
G
I
A
V
N
A
L
R
Q
G
G
V
----
D
V
A
S
L
E
V
A
V
L
D
Q
-
S
R
-
P
R
-----------------------------
R
A
F
R
R
I
A
G
T
A
L
E
Q
L
V
P
A
E
---