@TOME V3
(Feb 2022)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
3D Alignment Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
3D Alignment Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
PDB Ligands
Affinity Score
Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
Sequence Alignment
Tab of Complexes
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PSD11_HUMAN: (2020-02-02 )
MAAAAVVEFQRAQSLLSTDREASIDILHSIVKRDIQENDEEAVQVKEQSILELGSLLAKTGQAAELGGLLKYVRPFLNSISKAKAARLVRSLLDLFLDMEAATGQEVELCLECIEWAKSEKRTFLRQALEARLVSLYFDTKRYQEALHLGSQLLRELKKMDDKALLVEVQLLESKTYHALSNLPKARAALTSARTTANAIYCPPKLQATLDMQSGIIHAAEEKDWKTAYSYFYEAFEGYDSIDSPKAITSLKYMLLCKIMLNTPEDVQALVSGKLALRYAGRQTEALKCVAQASKNRSLADFEKALTDYRAELRDDPIISTHLAKLYDNLLEQNLIRVIEPFSRVQIEHISSLIKLSKADVERKLSQMILDKKFHGILDQGEGVLIIFDEPPVDKTYEAALETIQNMSKVVDSLYNKAKKLT
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200...-....210.......220........230.......240..----.....250.......260.......270.......280........290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MA
A
A
A
V
V
E
F
Q
R
A
Q
S
L
L
STDR
E
A
S
I
D
I
L
H
S
I
V
K
R
D
I
QEN
D
E
E
A
V
Q
V
K
E
Q
S
I
L
E
L
G
S
L
L
A
KTG
Q
A
A
E
L
G
G
L
L
K
Y
V
R
P
F
L
N
S
I
S
K
A
K
A
A
R
L
V
R
S
L
L
D
L
F
L
DMEAAT
G
Q
E
V
E
L
C
L
E
C
I
E
W
A
K
S
E
K
R
T
F
L
R
Q
A
L
E
A
R
L
V
S
L
Y
FD
T
K
R
Y
Q
E
A
L
H
L
G
S
Q
L
L
R
E
L
K
KMDD
K
A
L
L
V
E
V
Q
LLESK
T
Y
H
A
L
S
NL
P
K
A
R
A
A
L
TSARTTA
N
A
I
YCPPK-L
Q
A
T
L
DMQSG
I
I
H
AAE-EK
D
W
K
T
A
Y
S
Y
F
Y
E
A
F
EGYDSIDS----
P
K
A
I
T
S
L
K
Y
M
L
L
C
K
I
MLNT
P
E
D
V
Q
A
L
VSG
K
L
A
L
R
YA-GR
Q
T
E
A
L
K
C
V
A
Q
ASKNR
S
L
A
D
F
E
K
A
L
T
D
Y
R
A
E
LRDDP
I
I
S
T
H
L
A
K
L
Y
D
N
L
L
E
Q
N
L
I
R
V
IE
P
F
S
R
V
Q
I
E
H
I
S
S
L
I
K
L
S
K
A
D
V
E
R
K
L
S
Q
M
I
L
D
K
K
F
H
G
I
LDQGE
G
V
L
I
I
FDEPPV
D
K
T
Y
E
A
A
L
E
T
I
Q
N
M
S
K
V
V
D
S
L
Y
N
K
A
KKLT
7
PsiBlast_PDB
93.06
100%
-108
- C3 -
-
5LN3
-
PSD11_HUMAN
Q:
[1-422]
M
A
A
A
A
V
V
E
F
Q
R
A
Q
S
L
L
S
T
D
R
E
A
S
I
D
I
L
H
S
I
V
K
R
D
I
Q
E
N
D
E
E
A
V
Q
V
K
E
Q
S
I
L
E
L
G
S
L
L
A
K
T
G
Q
A
A
E
L
G
G
L
L
K
Y
V
R
P
F
L
N
S
I
S
K
A
K
A
A
R
L
V
R
S
L
L
D
L
F
L
D
M
E
A
A
T
G
Q
E
V
E
L
C
L
E
C
I
E
W
A
K
S
E
K
R
T
F
L
R
Q
A
L
E
A
R
L
V
S
L
Y
F
D
T
K
R
Y
Q
E
A
L
H
L
G
S
Q
L
L
R
E
L
K
K
M
D
D
K
A
L
L
V
E
V
Q
L
L
E
S
K
T
Y
H
A
L
S
N
L
P
K
A
R
A
A
L
T
S
A
R
T
T
A
N
A
I
Y
C
P
P
K
-
L
Q
A
T
L
D
M
Q
S
G
I
I
H
A
A
E
-
E
K
D
W
K
T
A
Y
S
Y
F
Y
E
A
F
E
G
Y
D
S
I
D
S
----
P
K
A
I
T
S
L
K
Y
M
L
L
C
K
I
M
L
N
T
P
E
D
V
Q
A
L
V
S
G
K
L
A
L
R
Y
A
-
G
R
Q
T
E
A
L
K
C
V
A
Q
A
S
K
N
R
S
L
A
D
F
E
K
A
L
T
D
Y
R
A
E
L
R
D
D
P
I
I
S
T
H
L
A
K
L
Y
D
N
L
L
E
Q
N
L
I
R
V
I
E
P
F
S
R
V
Q
I
E
H
I
S
S
L
I
K
L
S
K
A
D
V
E
R
K
L
S
Q
M
I
L
D
K
K
F
H
G
I
L
D
Q
G
E
G
V
L
I
I
F
D
E
P
P
V
D
K
T
Y
E
A
A
L
E
T
I
Q
N
M
S
K
V
V
D
S
L
Y
N
K
A
K
K
L
T
11
PsiBlast_PDB
90.28
100%
-101
- C3 -
-
6EPF
-
PSD11_RAT
Q:
[1-422]
M
A
A
A
A
V
V
E
F
Q
R
A
Q
S
L
L
S
T
D
R
E
A
S
I
D
I
L
H
S
I
V
K
R
D
I
Q
E
N
D
E
E
A
V
Q
V
K
E
Q
S
I
L
E
L
G
S
L
L
A
K
T
G
Q
A
A
E
L
G
G
L
L
K
Y
V
R
P
F
L
N
S
I
S
K
A
K
A
A
R
L
V
R
S
L
L
D
L
F
L
D
M
E
A
A
T
G
Q
E
V
E
L
C
L
E
C
I
E
W
A
K
S
E
K
R
T
F
L
R
Q
A
L
E
A
R
L
V
S
L
Y
F
D
T
K
R
Y
Q
E
A
L
H
L
G
S
Q
L
L
R
E
L
K
K
M
D
D
K
A
L
L
V
E
V
Q
L
L
E
S
K
T
Y
H
A
L
S
N
L
P
K
A
R
A
A
L
T
S
A
R
T
T
A
N
A
I
Y
C
P
P
K
-
L
Q
A
T
L
D
M
Q
S
G
I
I
H
A
A
E
-
E
K
D
W
K
T
A
Y
S
Y
F
Y
E
A
F
E
G
Y
D
S
I
D
S
----
P
K
A
I
T
S
L
K
Y
M
L
L
C
K
I
M
L
N
T
P
E
D
V
Q
A
L
V
S
G
K
L
A
L
R
Y
A
-
G
R
Q
T
E
A
L
K
C
V
A
Q
A
S
K
N
R
S
L
A
D
F
E
K
A
L
T
D
Y
R
A
E
L
R
D
D
P
I
I
S
T
H
L
A
K
L
Y
D
N
L
L
E
Q
N
L
I
R
V
I
E
P
F
S
R
V
Q
I
E
H
I
S
S
L
I
K
L
S
K
A
D
V
E
R
K
L
S
Q
M
I
L
D
K
K
F
H
G
I
L
D
Q
G
E
G
V
L
I
I
F
D
E
P
P
V
D
K
T
Y
E
A
A
L
E
T
I
Q
N
M
S
K
V
V
D
S
L
Y
N
K
A
K
K
L
T
2
PsiBlast_PDB
89.28
100%
-103
- C3 -
-
5L4K
-
PSD11_HUMAN
Q:
[1-422]
M
A
A
A
A
V
V
E
F
Q
R
A
Q
S
L
L
S
T
D
R
E
A
S
I
D
I
L
H
S
I
V
K
R
D
I
Q
E
N
D
E
E
A
V
Q
V
K
E
Q
S
I
L
E
L
G
S
L
L
A
K
T
G
Q
A
A
E
L
G
G
L
L
K
Y
V
R
P
F
L
N
S
I
S
K
A
K
A
A
R
L
V
R
S
L
L
D
L
F
L
D
M
E
A
A
T
G
Q
E
V
E
L
C
L
E
C
I
E
W
A
K
S
E
K
R
T
F
L
R
Q
A
L
E
A
R
L
V
S
L
Y
F
D
T
K
R
Y
Q
E
A
L
H
L
G
S
Q
L
L
R
E
L
K
K
M
D
D
K
A
L
L
V
E
V
Q
L
L
E
S
K
T
Y
H
A
L
S
N
L
P
K
A
R
A
A
L
T
S
A
R
T
T
A
N
A
I
Y
C
P
P
K
-
L
Q
A
T
L
D
M
Q
S
G
I
I
H
A
A
E
-
E
K
D
W
K
T
A
Y
S
Y
F
Y
E
A
F
E
G
Y
D
S
I
D
S
----
P
K
A
I
T
S
L
K
Y
M
L
L
C
K
I
M
L
N
T
P
E
D
V
Q
A
L
V
S
G
K
L
A
L
R
Y
A
-
G
R
Q
T
E
A
L
K
C
V
A
Q
A
S
K
N
R
S
L
A
D
F
E
K
A
L
T
D
Y
R
A
E
L
R
D
D
P
I
I
S
T
H
L
A
K
L
Y
D
N
L
L
E
Q
N
L
I
R
V
I
E
P
F
S
R
V
Q
I
E
H
I
S
S
L
I
K
L
S
K
A
D
V
E
R
K
L
S
Q
M
I
L
D
K
K
F
H
G
I
L
D
Q
G
E
G
V
L
I
I
F
D
E
P
P
V
D
K
T
Y
E
A
A
L
E
T
I
Q
N
M
S
K
V
V
D
S
L
Y
N
K
A
K
K
L
T
8
PsiBlast_PDB
88.40
100%
-95
- C3 -
-
6EPC
-
PSD11_RAT
Q:
[1-422]
M
A
A
A
A
V
V
E
F
Q
R
A
Q
S
L
L
S
T
D
R
E
A
S
I
D
I
L
H
S
I
V
K
R
D
I
Q
E
N
D
E
E
A
V
Q
V
K
E
Q
S
I
L
E
L
G
S
L
L
A
K
T
G
Q
A
A
E
L
G
G
L
L
K
Y
V
R
P
F
L
N
S
I
S
K
A
K
A
A
R
L
V
R
S
L
L
D
L
F
L
D
M
E
A
A
T
G
Q
E
V
E
L
C
L
E
C
I
E
W
A
K
S
E
K
R
T
F
L
R
Q
A
L
E
A
R
L
V
S
L
Y
F
D
T
K
R
Y
Q
E
A
L
H
L
G
S
Q
L
L
R
E
L
K
K
M
D
D
K
A
L
L
V
E
V
Q
L
L
E
S
K
T
Y
H
A
L
S
N
L
P
K
A
R
A
A
L
T
S
A
R
T
T
A
N
A
I
Y
C
P
P
K
-
L
Q
A
T
L
D
M
Q
S
G
I
I
H
A
A
E
-
E
K
D
W
K
T
A
Y
S
Y
F
Y
E
A
F
E
G
Y
D
S
I
D
S
----
P
K
A
I
T
S
L
K
Y
M
L
L
C
K
I
M
L
N
T
P
E
D
V
Q
A
L
V
S
G
K
L
A
L
R
Y
A
-
G
R
Q
T
E
A
L
K
C
V
A
Q
A
S
K
N
R
S
L
A
D
F
E
K
A
L
T
D
Y
R
A
E
L
R
D
D
P
I
I
S
T
H
L
A
K
L
Y
D
N
L
L
E
Q
N
L
I
R
V
I
E
P
F
S
R
V
Q
I
E
H
I
S
S
L
I
K
L
S
K
A
D
V
E
R
K
L
S
Q
M
I
L
D
K
K
F
H
G
I
L
D
Q
G
E
G
V
L
I
I
F
D
E
P
P
V
D
K
T
Y
E
A
A
L
E
T
I
Q
N
M
S
K
V
V
D
S
L
Y
N
K
A
K
K
L
T
1
PsiBlast_PDB
88.06
100%
-86
- C3 -
-
5GJQ
-
PSD11_HUMAN
Q:
[2-422]
-
A
A
A
A
V
V
E
F
Q
R
A
Q
S
L
L
S
T
D
R
E
A
S
I
D
I
L
H
S
I
V
K
R
D
I
Q
E
N
D
E
E
A
V
Q
V
K
E
Q
S
I
L
E
L
G
S
L
L
A
K
T
G
Q
A
A
E
L
G
G
L
L
K
Y
V
R
P
F
L
N
S
I
S
K
A
K
A
A
R
L
V
R
S
L
L
D
L
F
L
D
M
E
A
A
T
G
Q
E
V
E
L
C
L
E
C
I
E
W
A
K
S
E
K
R
T
F
L
R
Q
A
L
E
A
R
L
V
S
L
Y
F
D
T
K
R
Y
Q
E
A
L
H
L
G
S
Q
L
L
R
E
L
K
K
M
D
D
K
A
L
L
V
E
V
Q
L
L
E
S
K
T
Y
H
A
L
S
N
L
P
K
A
R
A
A
L
T
S
A
R
T
T
A
N
A
I
Y
C
P
P
K
-
L
Q
A
T
L
D
M
Q
S
G
I
I
H
A
A
E
-
E
K
D
W
K
T
A
Y
S
Y
F
Y
E
A
F
E
G
Y
D
S
I
D
S
----
P
K
A
I
T
S
L
K
Y
M
L
L
C
K
I
M
L
N
T
P
E
D
V
Q
A
L
V
S
G
K
L
A
L
R
Y
A
-
G
R
Q
T
E
A
L
K
C
V
A
Q
A
S
K
N
R
S
L
A
D
F
E
K
A
L
T
D
Y
R
A
E
L
R
D
D
P
I
I
S
T
H
L
A
K
L
Y
D
N
L
L
E
Q
N
L
I
R
V
I
E
P
F
S
R
V
Q
I
E
H
I
S
S
L
I
K
L
S
K
A
D
V
E
R
K
L
S
Q
M
I
L
D
K
K
F
H
G
I
L
D
Q
G
E
G
V
L
I
I
F
D
E
P
P
V
D
K
T
Y
E
A
A
L
E
T
I
Q
N
M
S
K
V
V
D
S
L
Y
N
K
A
K
K
L
T
14
PsiBlast_PDB
86.45
100%
-121
- C3 -
-
5VHH
-
PSD11_HUMAN
X:
[1-385]
-------------------------------------
N
D
E
E
A
V
Q
V
K
E
Q
S
I
L
E
L
G
S
L
L
A
K
T
G
Q
A
A
E
L
G
G
L
L
K
Y
V
R
P
F
L
N
S
I
S
K
A
K
A
A
R
L
V
R
S
L
L
D
L
F
L
D
M
E
A
A
T
G
Q
E
V
E
L
C
L
E
C
I
E
W
A
K
S
E
K
R
T
F
L
R
Q
A
L
E
A
R
L
V
S
L
Y
F
D
T
K
R
Y
Q
E
A
L
H
L
G
S
Q
L
L
R
E
L
K
K
M
D
D
K
A
L
L
V
E
V
Q
L
L
E
S
K
T
Y
H
A
L
S
N
L
P
K
A
R
A
A
L
T
S
A
R
T
T
A
N
A
I
Y
C
P
P
K
-
L
Q
A
T
L
D
M
Q
S
G
I
I
H
A
A
E
-
E
K
D
W
K
T
A
Y
S
Y
F
Y
E
A
F
E
G
Y
D
S
I
D
S
----
P
K
A
I
T
S
L
K
Y
M
L
L
C
K
I
M
L
N
T
P
E
D
V
Q
A
L
V
S
G
K
L
A
L
R
Y
A
-
G
R
Q
T
E
A
L
K
C
V
A
Q
A
S
K
N
R
S
L
A
D
F
E
K
A
L
T
D
Y
R
A
E
L
R
D
D
P
I
I
S
T
H
L
A
K
L
Y
D
N
L
L
E
Q
N
L
I
R
V
I
E
P
F
S
R
V
Q
I
E
H
I
S
S
L
I
K
L
S
K
A
D
V
E
R
K
L
S
Q
M
I
L
D
K
K
F
H
G
I
L
D
Q
G
E
G
V
L
I
I
F
D
E
P
P
V
D
K
T
Y
E
A
A
L
E
T
I
Q
N
M
S
K
V
V
D
S
L
Y
N
K
A
K
K
L
T
13
PsiBlast_PDB
86.44
100%
-123
- C3 -
-
5VHF
-
PSD11_HUMAN
X:
[1-385]
-------------------------------------
N
D
E
E
A
V
Q
V
K
E
Q
S
I
L
E
L
G
S
L
L
A
K
T
G
Q
A
A
E
L
G
G
L
L
K
Y
V
R
P
F
L
N
S
I
S
K
A
K
A
A
R
L
V
R
S
L
L
D
L
F
L
D
M
E
A
A
T
G
Q
E
V
E
L
C
L
E
C
I
E
W
A
K
S
E
K
R
T
F
L
R
Q
A
L
E
A
R
L
V
S
L
Y
F
D
T
K
R
Y
Q
E
A
L
H
L
G
S
Q
L
L
R
E
L
K
K
M
D
D
K
A
L
L
V
E
V
Q
L
L
E
S
K
T
Y
H
A
L
S
N
L
P
K
A
R
A
A
L
T
S
A
R
T
T
A
N
A
I
Y
C
P
P
K
-
L
Q
A
T
L
D
M
Q
S
G
I
I
H
A
A
E
-
E
K
D
W
K
T
A
Y
S
Y
F
Y
E
A
F
E
G
Y
D
S
I
D
S
----
P
K
A
I
T
S
L
K
Y
M
L
L
C
K
I
M
L
N
T
P
E
D
V
Q
A
L
V
S
G
K
L
A
L
R
Y
A
-
G
R
Q
T
E
A
L
K
C
V
A
Q
A
S
K
N
R
S
L
A
D
F
E
K
A
L
T
D
Y
R
A
E
L
R
D
D
P
I
I
S
T
H
L
A
K
L
Y
D
N
L
L
E
Q
N
L
I
R
V
I
E
P
F
S
R
V
Q
I
E
H
I
S
S
L
I
K
L
S
K
A
D
V
E
R
K
L
S
Q
M
I
L
D
K
K
F
H
G
I
L
D
Q
G
E
G
V
L
I
I
F
D
E
P
P
V
D
K
T
Y
E
A
A
L
E
T
I
Q
N
M
S
K
V
V
D
S
L
Y
N
K
A
K
K
L
T
12
PsiBlast_PDB
86.34
100%
-118
- C3 -
-
5VGZ
-
PSD11_HUMAN
X:
[1-385]
-------------------------------------
N
D
E
E
A
V
Q
V
K
E
Q
S
I
L
E
L
G
S
L
L
A
K
T
G
Q
A
A
E
L
G
G
L
L
K
Y
V
R
P
F
L
N
S
I
S
K
A
K
A
A
R
L
V
R
S
L
L
D
L
F
L
D
M
E
A
A
T
G
Q
E
V
E
L
C
L
E
C
I
E
W
A
K
S
E
K
R
T
F
L
R
Q
A
L
E
A
R
L
V
S
L
Y
F
D
T
K
R
Y
Q
E
A
L
H
L
G
S
Q
L
L
R
E
L
K
K
M
D
D
K
A
L
L
V
E
V
Q
L
L
E
S
K
T
Y
H
A
L
S
N
L
P
K
A
R
A
A
L
T
S
A
R
T
T
A
N
A
I
Y
C
P
P
K
-
L
Q
A
T
L
D
M
Q
S
G
I
I
H
A
A
E
-
E
K
D
W
K
T
A
Y
S
Y
F
Y
E
A
F
E
G
Y
D
S
I
D
S
----
P
K
A
I
T
S
L
K
Y
M
L
L
C
K
I
M
L
N
T
P
E
D
V
Q
A
L
V
S
G
K
L
A
L
R
Y
A
-
G
R
Q
T
E
A
L
K
C
V
A
Q
A
S
K
N
R
S
L
A
D
F
E
K
A
L
T
D
Y
R
A
E
L
R
D
D
P
I
I
S
T
H
L
A
K
L
Y
D
N
L
L
E
Q
N
L
I
R
V
I
E
P
F
S
R
V
Q
I
E
H
I
S
S
L
I
K
L
S
K
A
D
V
E
R
K
L
S
Q
M
I
L
D
K
K
F
H
G
I
L
D
Q
G
E
G
V
L
I
I
F
D
E
P
P
V
D
K
T
Y
E
A
A
L
E
T
I
Q
N
M
S
K
V
V
D
S
L
Y
N
K
A
K
K
L
T
9
PsiBlast_PDB
86.25
100%
-83
- C3 -
-
6EPD
-
PSD11_RAT
Q:
[1-422]
M
A
A
A
A
V
V
E
F
Q
R
A
Q
S
L
L
S
T
D
R
E
A
S
I
D
I
L
H
S
I
V
K
R
D
I
Q
E
N
D
E
E
A
V
Q
V
K
E
Q
S
I
L
E
L
G
S
L
L
A
K
T
G
Q
A
A
E
L
G
G
L
L
K
Y
V
R
P
F
L
N
S
I
S
K
A
K
A
A
R
L
V
R
S
L
L
D
L
F
L
D
M
E
A
A
T
G
Q
E
V
E
L
C
L
E
C
I
E
W
A
K
S
E
K
R
T
F
L
R
Q
A
L
E
A
R
L
V
S
L
Y
F
D
T
K
R
Y
Q
E
A
L
H
L
G
S
Q
L
L
R
E
L
K
K
M
D
D
K
A
L
L
V
E
V
Q
L
L
E
S
K
T
Y
H
A
L
S
N
L
P
K
A
R
A
A
L
T
S
A
R
T
T
A
N
A
I
Y
C
P
P
K
-
L
Q
A
T
L
D
M
Q
S
G
I
I
H
A
A
E
-
E
K
D
W
K
T
A
Y
S
Y
F
Y
E
A
F
E
G
Y
D
S
I
D
S
----
P
K
A
I
T
S
L
K
Y
M
L
L
C
K
I
M
L
N
T
P
E
D
V
Q
A
L
V
S
G
K
L
A
L
R
Y
A
-
G
R
Q
T
E
A
L
K
C
V
A
Q
A
S
K
N
R
S
L
A
D
F
E
K
A
L
T
D
Y
R
A
E
L
R
D
D
P
I
I
S
T
H
L
A
K
L
Y
D
N
L
L
E
Q
N
L
I
R
V
I
E
P
F
S
R
V
Q
I
E
H
I
S
S
L
I
K
L
S
K
A
D
V
E
R
K
L
S
Q
M
I
L
D
K
K
F
H
G
I
L
D
Q
G
E
G
V
L
I
I
F
D
E
P
P
V
D
K
T
Y
E
A
A
L
E
T
I
Q
N
M
S
K
V
V
D
S
L
Y
N
K
A
K
K
L
T
15
PsiBlast_PDB
85.31
100%
-121
- C3 -
-
5VHI
-
PSD11_HUMAN
X:
[1-385]
-------------------------------------
N
D
E
E
A
V
Q
V
K
E
Q
S
I
L
E
L
G
S
L
L
A
K
T
G
Q
A
A
E
L
G
G
L
L
K
Y
V
R
P
F
L
N
S
I
S
K
A
K
A
A
R
L
V
R
S
L
L
D
L
F
L
D
M
E
A
A
T
G
Q
E
V
E
L
C
L
E
C
I
E
W
A
K
S
E
K
R
T
F
L
R
Q
A
L
E
A
R
L
V
S
L
Y
F
D
T
K
R
Y
Q
E
A
L
H
L
G
S
Q
L
L
R
E
L
K
K
M
D
D
K
A
L
L
V
E
V
Q
L
L
E
S
K
T
Y
H
A
L
S
N
L
P
K
A
R
A
A
L
T
S
A
R
T
T
A
N
A
I
Y
C
P
P
K
-
L
Q
A
T
L
D
M
Q
S
G
I
I
H
A
A
E
-
E
K
D
W
K
T
A
Y
S
Y
F
Y
E
A
F
E
G
Y
D
S
I
D
S
----
P
K
A
I
T
S
L
K
Y
M
L
L
C
K
I
M
L
N
T
P
E
D
V
Q
A
L
V
S
G
K
L
A
L
R
Y
A
-
G
R
Q
T
E
A
L
K
C
V
A
Q
A
S
K
N
R
S
L
A
D
F
E
K
A
L
T
D
Y
R
A
E
L
R
D
D
P
I
I
S
T
H
L
A
K
L
Y
D
N
L
L
E
Q
N
L
I
R
V
I
E
P
F
S
R
V
Q
I
E
H
I
S
S
L
I
K
L
S
K
A
D
V
E
R
K
L
S
Q
M
I
L
D
K
K
F
H
G
I
L
D
Q
G
E
G
V
L
I
I
F
D
E
P
P
V
D
K
T
Y
E
A
A
L
E
T
I
Q
N
M
S
K
V
V
D
S
L
Y
N
K
A
K
K
L
T
10
PsiBlast_PDB
83.42
100%
-76
- C3 -
-
6EPE
-
PSD11_RAT
Q:
[1-422]
M
A
A
A
A
V
V
E
F
Q
R
A
Q
S
L
L
S
T
D
R
E
A
S
I
D
I
L
H
S
I
V
K
R
D
I
Q
E
N
D
E
E
A
V
Q
V
K
E
Q
S
I
L
E
L
G
S
L
L
A
K
T
G
Q
A
A
E
L
G
G
L
L
K
Y
V
R
P
F
L
N
S
I
S
K
A
K
A
A
R
L
V
R
S
L
L
D
L
F
L
D
M
E
A
A
T
G
Q
E
V
E
L
C
L
E
C
I
E
W
A
K
S
E
K
R
T
F
L
R
Q
A
L
E
A
R
L
V
S
L
Y
F
D
T
K
R
Y
Q
E
A
L
H
L
G
S
Q
L
L
R
E
L
K
K
M
D
D
K
A
L
L
V
E
V
Q
L
L
E
S
K
T
Y
H
A
L
S
N
L
P
K
A
R
A
A
L
T
S
A
R
T
T
A
N
A
I
Y
C
P
P
K
-
L
Q
A
T
L
D
M
Q
S
G
I
I
H
A
A
E
-
E
K
D
W
K
T
A
Y
S
Y
F
Y
E
A
F
E
G
Y
D
S
I
D
S
----
P
K
A
I
T
S
L
K
Y
M
L
L
C
K
I
M
L
N
T
P
E
D
V
Q
A
L
V
S
G
K
L
A
L
R
Y
A
-
G
R
Q
T
E
A
L
K
C
V
A
Q
A
S
K
N
R
S
L
A
D
F
E
K
A
L
T
D
Y
R
A
E
L
R
D
D
P
I
I
S
T
H
L
A
K
L
Y
D
N
L
L
E
Q
N
L
I
R
V
I
E
P
F
S
R
V
Q
I
E
H
I
S
S
L
I
K
L
S
K
A
D
V
E
R
K
L
S
Q
M
I
L
D
K
K
F
H
G
I
L
D
Q
G
E
G
V
L
I
I
F
D
E
P
P
V
D
K
T
Y
E
A
A
L
E
T
I
Q
N
M
S
K
V
V
D
S
L
Y
N
K
A
K
K
L
T
19
PsiBlast_PDB
80.96
70%
-137
- C3 -
-
3TXM
-
PSD11_DROME
A:
[10-362]
-------------------------------------
N
D
E
E
R
I
R
I
K
E
Q
G
I
L
Q
Q
G
E
L
Y
K
Q
E
G
K
A
K
E
L
A
D
L
I
K
V
T
R
P
F
L
S
S
I
S
K
A
K
A
A
K
L
V
R
S
L
V
D
M
F
L
D
M
D
A
G
T
G
I
E
V
Q
L
C
K
D
C
I
E
W
A
K
Q
E
K
R
T
F
L
R
Q
S
L
E
A
R
L
I
A
L
Y
F
D
T
A
L
Y
T
E
A
L
A
L
G
A
Q
L
L
R
E
L
K
K
L
D
D
K
N
L
L
V
E
V
Q
L
L
E
S
K
T
Y
H
A
L
S
N
L
P
K
A
R
A
A
L
T
S
A
R
T
T
A
N
A
I
Y
C
P
P
K
-
V
Q
G
A
L
D
L
Q
S
G
I
L
H
A
A
D
-
E
R
D
F
K
T
A
F
S
Y
F
Y
E
A
F
E
G
F
D
S
V
D
S
----
V
K
A
L
T
S
L
K
Y
M
L
L
C
K
I
M
L
G
Q
S
D
D
V
N
Q
L
V
S
G
K
L
A
I
T
Y
S
-
G
R
D
I
D
A
M
K
S
V
A
E
A
S
H
K
R
S
L
A
D
F
Q
A
A
L
K
E
Y
K
K
E
L
A
E
D
V
I
V
Q
A
H
L
G
T
L
Y
D
T
M
L
E
Q
N
L
C
R
I
I
E
P
Y
S
R
V
Q
V
A
H
V
A
E
S
I
Q
L
P
M
P
Q
V
E
K
K
L
S
Q
M
I
L
D
K
K
F
S
G
I
L
D
Q
G
E
G
V
L
I
V
F
E
E
--------------------------------
21
Fugue
80.83
70%
-135
- C3 -
-
3TXN
2
PSD11_DROME
A:
[10-362]
-------------------------------------
N
D
E
E
R
I
R
I
K
E
Q
G
I
L
Q
Q
G
E
L
Y
K
Q
E
G
K
A
K
E
L
A
D
L
I
K
V
T
R
P
F
L
S
S
I
S
K
A
K
A
A
K
L
V
R
S
L
V
D
M
F
L
D
M
D
A
G
T
G
I
E
V
Q
L
C
K
D
C
I
E
W
A
K
Q
E
K
R
T
F
L
R
Q
S
L
E
A
R
L
I
A
L
Y
F
D
T
A
L
Y
T
E
A
L
A
L
G
A
Q
L
L
R
E
L
K
K
L
D
D
K
N
L
L
V
E
V
Q
L
L
E
S
K
T
Y
H
A
L
S
N
L
P
K
A
R
A
A
L
T
S
A
R
T
T
A
N
A
I
Y
C
P
P
K
-
V
Q
G
A
L
D
L
Q
S
G
I
L
H
A
A
D
-
E
R
D
F
K
T
A
F
S
Y
F
Y
E
A
F
E
G
F
D
S
V
D
S
----
V
K
A
L
T
S
L
K
Y
M
L
L
C
K
I
M
L
G
Q
S
D
D
V
N
Q
L
V
S
G
K
L
A
I
T
Y
S
-
G
R
D
I
D
A
M
K
S
V
A
E
A
S
H
K
R
S
L
A
D
F
Q
A
A
L
K
E
Y
K
K
E
L
A
E
D
V
I
V
Q
A
H
L
G
T
L
Y
D
T
M
L
E
Q
N
L
C
R
I
I
E
P
Y
S
R
V
Q
V
A
H
V
A
E
S
I
Q
L
P
M
P
Q
V
E
K
K
L
S
Q
M
I
L
D
K
K
F
S
G
I
L
D
Q
G
E
G
V
L
I
V
F
E
E
--------------------------------
20
PsiBlast_PDB
80.83
70%
-135
- C3 -
-
3TXN
2
PSD11_DROME
A:
[10-362]
-------------------------------------
N
D
E
E
R
I
R
I
K
E
Q
G
I
L
Q
Q
G
E
L
Y
K
Q
E
G
K
A
K
E
L
A
D
L
I
K
V
T
R
P
F
L
S
S
I
S
K
A
K
A
A
K
L
V
R
S
L
V
D
M
F
L
D
M
D
A
G
T
G
I
E
V
Q
L
C
K
D
C
I
E
W
A
K
Q
E
K
R
T
F
L
R
Q
S
L
E
A
R
L
I
A
L
Y
F
D
T
A
L
Y
T
E
A
L
A
L
G
A
Q
L
L
R
E
L
K
K
L
D
D
K
N
L
L
V
E
V
Q
L
L
E
S
K
T
Y
H
A
L
S
N
L
P
K
A
R
A
A
L
T
S
A
R
T
T
A
N
A
I
Y
C
P
P
K
-
V
Q
G
A
L
D
L
Q
S
G
I
L
H
A
A
D
-
E
R
D
F
K
T
A
F
S
Y
F
Y
E
A
F
E
G
F
D
S
V
D
S
----
V
K
A
L
T
S
L
K
Y
M
L
L
C
K
I
M
L
G
Q
S
D
D
V
N
Q
L
V
S
G
K
L
A
I
T
Y
S
-
G
R
D
I
D
A
M
K
S
V
A
E
A
S
H
K
R
S
L
A
D
F
Q
A
A
L
K
E
Y
K
K
E
L
A
E
D
V
I
V
Q
A
H
L
G
T
L
Y
D
T
M
L
E
Q
N
L
C
R
I
I
E
P
Y
S
R
V
Q
V
A
H
V
A
E
S
I
Q
L
P
M
P
Q
V
E
K
K
L
S
Q
M
I
L
D
K
K
F
S
G
I
L
D
Q
G
E
G
V
L
I
V
F
E
E
--------------------------------
38
HHSearch
70.37
69%
-44
- C3 -
-
3TXN
2
PSD11_DROME
A:
[16-362]
-------------------------------------------
R
I
K
E
Q
G
I
L
Q
Q
G
E
L
Y
K
Q
E
G
K
A
K
E
L
A
D
L
I
K
V
T
R
P
F
L
S
S
I
S
K
A
K
A
A
K
L
V
R
S
L
V
D
M
F
L
D
M
D
A
G
T
G
I
E
V
Q
L
C
K
D
C
I
E
W
A
K
Q
E
K
R
T
F
L
R
Q
S
L
E
A
R
L
I
A
L
Y
F
D
T
A
L
Y
T
E
A
L
A
L
G
A
Q
L
L
R
E
L
K
K
L
D
D
K
N
L
L
V
E
V
Q
L
L
E
S
K
T
Y
H
A
L
S
N
L
P
K
A
R
A
A
L
T
S
A
R
T
T
A
N
A
I
Y
C
P
P
K
-
V
Q
G
A
L
D
L
Q
S
G
I
L
H
A
-
A
D
E
R
D
F
K
T
A
F
S
Y
F
Y
E
A
F
E
G
F
D
S
V
D
S
----
V
K
A
L
T
S
L
K
Y
M
L
L
C
K
I
M
L
G
Q
S
D
D
V
N
Q
L
-
V
S
G
K
L
A
I
T
Y
S
G
R
D
I
D
A
M
K
S
V
A
E
A
S
H
K
R
S
L
A
D
F
Q
A
A
L
K
E
Y
K
K
E
L
A
E
D
V
I
V
Q
A
H
L
G
T
L
Y
D
T
M
L
E
Q
N
L
C
R
I
I
E
P
Y
S
R
V
Q
V
A
H
V
A
E
S
I
Q
L
P
M
P
Q
V
E
K
K
L
S
Q
M
I
L
D
K
K
F
S
G
I
L
D
Q
G
E
G
V
L
I
V
F
E
E
--------------------------------
16
PsiBlast_PDB
64.49
100%
-112
- C3 -
-
5VHS
-
PSD11_HUMAN
X:
[106-385]
----------------------------------------------------------------------------------------------------------------------------------------------
Y
Q
E
A
L
H
L
G
S
Q
L
L
R
E
L
K
K
M
D
D
K
A
L
L
V
E
V
Q
L
L
E
S
K
T
Y
H
A
L
S
N
L
P
K
A
R
A
A
L
T
S
A
R
T
T
A
N
A
I
Y
C
P
P
K
-
L
Q
A
T
L
D
M
Q
S
G
I
I
H
A
A
E
-
E
K
D
W
K
T
A
Y
S
Y
F
Y
E
A
F
E
G
Y
D
S
I
D
S
----
P
K
A
I
T
S
L
K
Y
M
L
L
C
K
I
M
L
N
T
P
E
D
V
Q
A
L
V
S
G
K
L
A
L
R
Y
A
-
G
R
Q
T
E
A
L
K
C
V
A
Q
A
S
K
N
R
S
L
A
D
F
E
K
A
L
T
D
Y
R
A
E
L
R
D
D
P
I
I
S
T
H
L
A
K
L
Y
D
N
L
L
E
Q
N
L
I
R
V
I
E
P
F
S
R
V
Q
I
E
H
I
S
S
L
I
K
L
S
K
A
D
V
E
R
K
L
S
Q
M
I
L
D
K
K
F
H
G
I
L
D
Q
G
E
G
V
L
I
I
F
D
E
P
P
V
D
K
T
Y
E
A
A
L
E
T
I
Q
N
M
S
K
V
V
D
S
L
Y
N
K
A
K
K
L
T
22
Fugue
62.60
23%
-108
- C3 -
-
4D10
-
CSN2_HUMAN
B:
[34-447]
--
V
D
L
E
N
Q
Y
Y
N
S
K
A
L
K
E
D
D
P
K
A
A
L
S
S
F
Q
K
V
L
E
L
E
-
G
E
K
G
E
W
G
F
K
A
L
K
Q
M
I
K
I
N
F
K
L
T
N
F
P
E
M
M
N
R
Y
K
Q
L
L
T
Y
I
R
S
---
A
V
T
R
N
Y
S
E
K
S
I
N
S
I
L
D
-
Y
I
S
T
S
K
Q
M
D
L
L
Q
E
F
Y
E
T
T
L
E
A
L
K
D
A
K
N
D
R
L
W
F
K
T
N
T
K
L
G
K
L
Y
L
E
R
E
E
Y
G
K
L
Q
K
I
L
R
Q
L
H
Q
S
C
Q
T
Q
-----
L
L
E
I
Y
A
L
E
I
Q
M
Y
T
A
Q
K
N
N
K
K
L
K
A
L
Y
E
Q
S
L
H
I
K
S
A
I
P
-
H
P
L
-
I
M
G
V
I
R
E
C
G
G
K
M
H
L
R
E
-
G
-
E
F
E
K
A
H
T
D
F
F
E
A
F
K
N
Y
D
E
S
G
S
----
P
R
R
T
T
C
L
K
Y
L
V
L
A
N
M
L
M
K
S
G
--
I
N
P
F
D
S
Q
E
A
K
P
Y
K
N
-
D
P
E
I
L
A
M
T
N
L
V
S
A
Y
Q
N
N
D
I
T
E
F
E
K
I
L
K
T
N
H
S
N
I
M
D
D
P
F
I
R
E
H
I
E
E
L
L
R
N
I
R
T
Q
V
L
I
K
L
I
K
P
Y
T
R
I
H
I
P
F
I
S
K
E
L
N
I
D
V
A
D
V
E
S
L
L
V
Q
C
I
L
D
N
T
I
H
G
R
I
D
Q
V
N
Q
L
L
E
L
D
H
Q
K
R
G
G
A
R
Y
T
A
L
D
K
W
T
N
Q
L
N
S
L
N
Q
A
V
V
S
K
L
A
---
40
HHSearch
61.20
43%
-15
- C3 -
-
3JCK
-
RPN6_YEAST
C:
[54-431]
---------------------------------------------
Q
E
T
S
I
L
E
L
G
Q
L
Y
V
T
M
G
A
K
D
K
L
R
E
F
I
P
H
S
T
E
Y
M
M
Q
F
A
K
S
K
T
V
K
V
L
K
T
L
I
E
K
F
E
Q
V
P
D
S
L
D
D
Q
I
F
V
C
E
K
S
I
E
F
A
K
R
E
K
R
V
F
L
K
H
S
L
S
I
K
L
A
T
L
H
Y
Q
K
K
Q
Y
K
D
S
L
A
L
I
N
D
L
L
R
E
F
K
K
L
D
D
K
P
S
L
V
D
V
H
L
L
E
S
K
V
Y
H
K
L
R
N
L
A
K
S
K
A
S
L
T
A
A
R
T
A
A
N
S
I
-
Y
C
P
T
Q
T
V
A
E
L
D
L
M
S
G
I
L
H
C
-
E
-
D
K
D
Y
K
T
A
F
S
Y
F
F
E
S
F
E
S
Y
H
N
L
T
T
HNSY
E
K
A
C
Q
V
L
K
Y
M
L
L
S
K
I
M
L
N
L
I
D
D
V
K
N
I
L
N
A
K
Y
T
K
E
T
Y
Q
S
R
G
I
D
A
M
K
A
V
A
E
A
Y
N
N
R
S
L
L
D
F
N
T
A
L
K
Q
Y
E
K
E
L
M
G
D
E
L
T
R
S
H
F
N
A
L
Y
D
T
L
L
E
S
N
L
C
K
I
I
E
P
F
E
C
V
E
I
S
H
I
S
K
I
I
G
L
D
T
Q
Q
V
E
G
K
L
S
Q
M
I
L
D
K
I
F
Y
G
V
L
D
Q
G
N
G
W
L
Y
V
Y
E
T
P
N
Q
D
A
T
Y
D
S
A
L
E
L
V
G
Q
L
N
K
V
V
D
Q
L
F
E
K
A
S
---
3
PsiBlast_PDB
58.95
100%
-
- C3 -
-
5T0G
-
PSD11_HUMAN
X:
[43-422]
------------------------------------------
V
Q
V
K
E
Q
S
I
L
E
L
G
S
L
L
A
K
T
G
Q
A
A
E
L
G
G
L
L
K
Y
V
R
P
F
L
N
S
I
S
K
A
K
A
A
R
L
V
R
S
L
L
D
L
F
L
D
M
E
A
A
T
G
Q
E
V
E
L
C
L
E
C
I
E
W
A
K
S
E
K
R
T
F
L
R
Q
A
L
E
A
R
L
V
S
L
Y
F
D
T
K
R
Y
Q
E
A
L
H
L
G
S
Q
L
L
R
E
L
K
K
M
D
D
K
A
L
L
V
E
V
Q
L
L
E
S
K
T
Y
H
A
L
S
N
L
P
K
A
R
A
A
L
T
S
A
R
T
T
A
N
A
I
Y
C
P
P
K
-
L
Q
A
T
L
D
M
Q
S
G
I
I
H
A
A
E
-
E
K
D
W
K
T
A
Y
S
Y
F
Y
E
A
F
E
G
Y
D
S
I
D
S
----
P
K
A
I
T
S
L
K
Y
M
L
L
C
K
I
M
L
N
T
P
E
D
V
Q
A
L
V
S
G
K
L
A
L
R
Y
A
-
G
R
Q
T
E
A
L
K
C
V
A
Q
A
S
K
N
R
S
L
A
D
F
E
K
A
L
T
D
Y
R
A
E
L
R
D
D
P
I
I
S
T
H
L
A
K
L
Y
D
N
L
L
E
Q
N
L
I
R
V
I
E
P
F
S
R
V
Q
I
E
H
I
S
S
L
I
K
L
S
K
A
D
V
E
R
K
L
S
Q
M
I
L
D
K
K
F
H
G
I
L
D
Q
G
E
G
V
L
I
I
F
D
E
P
P
V
D
K
T
Y
E
A
A
L
E
T
I
Q
N
M
S
K
V
V
D
S
L
Y
N
K
A
K
K
L
T
17
PsiBlast_PDB
55.45
100%
-108
- C3 -
-
5VFR
-
PSD11_HUMAN
X:
[182-422]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
L
P
K
A
R
A
A
L
T
S
A
R
T
T
A
N
A
I
Y
C
P
P
K
-
L
Q
A
T
L
D
M
Q
S
G
I
I
H
A
A
E
-
E
K
D
W
K
T
A
Y
S
Y
F
Y
E
A
F
E
G
Y
D
S
I
D
S
----
P
K
A
I
T
S
L
K
Y
M
L
L
C
K
I
M
L
N
T
P
E
D
V
Q
A
L
V
S
G
K
L
A
L
R
Y
A
-
G
R
Q
T
E
A
L
K
C
V
A
Q
A
S
K
N
R
S
L
A
D
F
E
K
A
L
T
D
Y
R
A
E
L
R
D
D
P
I
I
S
T
H
L
A
K
L
Y
D
N
L
L
E
Q
N
L
I
R
V
I
E
P
F
S
R
V
Q
I
E
H
I
S
S
L
I
K
L
S
K
A
D
V
E
R
K
L
S
Q
M
I
L
D
K
K
F
H
G
I
L
D
Q
G
E
G
V
L
I
I
F
D
E
P
P
V
D
K
T
Y
E
A
A
L
E
T
I
Q
N
M
S
K
V
V
D
S
L
Y
N
K
A
K
K
L
T