@TOME V3
(Feb 2022)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
3D Alignment Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
3D Alignment Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
PDB Ligands
Affinity Score
Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
Sequence Alignment
Tab of Complexes
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : ADRM1_HUMAN: (2020-01-31 )
MTTSGALFPSLVPGSRGASNKYLVEFRAGKMSLKGTTVTPDKRKGLVYIQQTDDSLIHFCWKDRTSGNVEDDLIIFPDDCEFKRVPQCPSGRVYVLKFKAGSKRLFFWMQEPKTDQDEEHCRKVNEYLNNPPMPGALGASGSSGHELSALGGEGGLQSLLGNMSHSQLMQLIGPAGLGGLGGLGALTGPGLASLLGSSGPPGSSSSSSSRSQSAAVTPSSTTSSTRATPAPSAPAAASATSPSPAPSSGNGASTAASPTQPIQLSDLQSILATMNVPAGPAGGQQVDLASVLTPEIMAPILANADVQERLLPYLPSGESLPQTADEIQNTLTSPQFQQALGMFSAALASGQLGPLMCQFGLPAEAVEAANKGDVEAFAKAMQNNAKPEQKEGDTKDKKDEEEDMSLD
Atome Classification :
(20 SA)
.........10........20........30.....--...40........50....---....60.......----.70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.....---..330.......340.......350.......360.......370.......380.......390.......400.....
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MTTSGALFPSLVPGSRGASN
K
Y
L
V
E
F
RAG
K
M
S
LKGT--TVTPDKRK
G
L
V
Y
I
QQTDD
S
---
L
I
H
F
C
WKDRTSGN----VED
D
L
I
I
FPDDCEFKRVPQCPSG
R
V
Y
V
L
K
FKAGS
K
R
L
F
F
W
M
QEPKTD
Q
D
E
E
H
C
R
K
V
N
E
Y
LNNPPMPGALGASGSSGH
E
L
SALGGEG
G
L
Q
S
L
L
GNM
S
H
S
Q
L
M
Q
L
IGPAGLGGLGGLGALTG
P
G
L
A
S
L
LGSSGPPGSSSSSSSRSQSAAVTPSSTTSSTRATPAPSAPAAASATSPSPAPSSGNGASTAASPTQ
P
I
Q
L
S
D
L
Q
S
I
L
A
T
MNVPAGPAGG
Q
Q
V
D
L
A
S
VL
T
P
E
I
M
A
P
I
LAN
A
D
V
Q
E
R
L
L
PYLPSGESLPQ
T
A
D
E
I
---
Q
N
TLT
S
P
Q
F
Q
Q
A
L
G
M
F
S
A
A
L
ASGQLG
P
L
M
C
QFGL
P
A
E
A
V
EAANKG
D
V
E
A
F
A
K
A
M
QNNAKPEQKEGDTKDKKDEEEDMSLD
21
Fugue
96.77
100%
-108
- C1 -
-
2KR0
-
ADRM1_HUMAN
A:
[1-407]
M
T
T
S
G
A
L
F
P
S
L
V
P
G
S
R
G
A
S
N
K
Y
L
V
E
F
R
A
G
K
M
S
L
K
G
T
--
T
V
T
P
D
K
R
K
G
L
V
Y
I
Q
Q
T
D
D
S
---
L
I
H
F
C
W
K
D
R
T
S
G
N
----
V
E
D
D
L
I
I
F
P
D
D
C
E
F
K
R
V
P
Q
C
P
S
G
R
V
Y
V
L
K
F
K
A
G
S
K
R
L
F
F
W
M
Q
E
P
K
T
D
Q
D
E
E
H
C
R
K
V
N
E
Y
L
N
N
P
P
M
P
G
A
L
G
A
S
G
S
S
G
H
E
L
S
A
L
G
G
E
G
G
L
Q
S
L
L
G
N
M
S
H
S
Q
L
M
Q
L
I
G
P
A
G
L
G
G
L
G
G
L
G
A
L
T
G
P
G
L
A
S
L
L
G
S
S
G
P
P
G
S
S
S
S
S
S
S
R
S
Q
S
A
A
V
T
P
S
S
T
T
S
S
T
R
A
T
P
A
P
S
A
P
A
A
A
S
A
T
S
P
S
P
A
P
S
S
G
N
G
A
S
T
A
A
S
P
T
Q
P
I
Q
L
S
D
L
Q
S
I
L
A
T
M
N
V
P
A
G
P
A
G
G
Q
Q
V
D
L
A
S
V
L
T
P
E
I
M
A
P
I
L
A
N
A
D
V
Q
E
R
L
L
P
Y
L
P
S
G
E
S
L
P
Q
T
A
D
E
I
---
Q
N
T
L
T
S
P
Q
F
Q
Q
A
L
G
M
F
S
A
A
L
A
S
G
Q
L
G
P
L
M
C
Q
F
G
L
P
A
E
A
V
E
A
A
N
K
G
D
V
E
A
F
A
K
A
M
Q
N
N
A
K
P
E
Q
K
E
G
D
T
K
D
K
K
D
E
E
E
D
M
S
L
D
1
PsiBlast_PDB
96.35
100%
-108
- C1 -
-
2KR0
-
ADRM1_HUMAN
A:
[1-407]
M
T
T
S
G
A
L
F
P
S
L
V
P
G
S
R
G
A
S
N
K
Y
L
V
E
F
R
A
G
K
M
S
L
K
G
T
--
T
V
T
P
D
K
R
K
G
L
V
Y
I
Q
Q
T
D
D
S
---
L
I
H
F
C
W
K
D
R
T
S
G
N
----
V
E
D
D
L
I
I
F
P
D
D
C
E
F
K
R
V
P
Q
C
P
S
G
R
V
Y
V
L
K
F
K
A
G
S
K
R
L
F
F
W
M
Q
E
P
K
T
D
Q
D
E
E
H
C
R
K
V
N
E
Y
L
N
N
P
P
M
P
G
A
L
G
A
S
G
S
S
G
H
E
L
S
A
L
G
G
E
G
G
L
Q
S
L
L
G
N
M
S
H
S
Q
L
M
Q
L
I
G
P
A
G
L
G
G
L
G
G
L
G
A
L
T
G
P
G
L
A
S
L
L
G
S
S
G
P
P
G
S
S
S
S
S
S
S
R
S
Q
S
A
A
V
T
P
S
S
T
T
S
S
T
R
A
T
P
A
P
S
A
P
A
A
A
S
A
T
S
P
S
P
A
P
S
S
G
N
G
A
S
T
A
A
S
P
T
Q
P
I
Q
L
S
D
L
Q
S
I
L
A
T
M
N
V
P
A
G
P
A
G
G
Q
Q
V
D
L
A
S
V
L
T
P
E
I
M
A
P
I
L
A
N
A
D
V
Q
E
R
L
L
P
Y
L
P
S
G
E
S
L
P
Q
T
A
D
E
I
---
Q
N
T
L
T
S
P
Q
F
Q
Q
A
L
G
M
F
S
A
A
L
A
S
G
Q
L
G
P
L
M
C
Q
F
G
L
P
A
E
A
V
E
A
A
N
K
G
D
V
E
A
F
A
K
A
M
Q
N
N
A
K
P
E
Q
K
E
G
D
T
K
D
K
K
D
E
E
E
D
M
S
L
D
23
Fugue
52.74
100%
-151
* C1 *
-
2KQZ
-
ADRM1_HUMAN
A:
[253-407]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
T
A
A
S
P
T
Q
P
I
Q
L
S
D
L
Q
S
I
L
A
T
M
N
V
P
A
G
P
A
G
G
Q
Q
V
D
L
A
S
V
L
T
P
E
I
M
A
P
I
L
A
N
A
D
V
Q
E
R
L
L
P
Y
L
P
S
G
E
S
L
P
Q
T
A
D
E
I
---
Q
N
T
L
T
S
P
Q
F
Q
Q
A
L
G
M
F
S
A
A
L
A
S
G
Q
L
G
P
L
M
C
Q
F
G
L
P
A
E
A
V
E
A
A
N
K
G
D
V
E
A
F
A
K
A
M
Q
N
N
A
K
P
E
Q
K
E
G
D
T
K
D
K
K
D
E
E
E
D
M
S
L
D
6
PsiBlast_PDB
52.74
100%
-151
- C1 -
-
2KQZ
-
ADRM1_HUMAN
A:
[253-407]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
T
A
A
S
P
T
Q
P
I
Q
L
S
D
L
Q
S
I
L
A
T
M
N
V
P
A
G
P
A
G
G
Q
Q
V
D
L
A
S
V
L
T
P
E
I
M
A
P
I
L
A
N
A
D
V
Q
E
R
L
L
P
Y
L
P
S
G
E
S
L
P
Q
T
A
D
E
I
---
Q
N
T
L
T
S
P
Q
F
Q
Q
A
L
G
M
F
S
A
A
L
A
S
G
Q
L
G
P
L
M
C
Q
F
G
L
P
A
E
A
V
E
A
A
N
K
G
D
V
E
A
F
A
K
A
M
Q
N
N
A
K
P
E
Q
K
E
G
D
T
K
D
K
K
D
E
E
E
D
M
S
L
D
9
PsiBlast_PDB
49.91
99%
-131
- C1 -
-
2MKZ
-
A:
[3-141]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
I
L
A
T
M
N
V
P
A
G
P
A
G
G
Q
Q
V
D
L
A
S
V
L
T
P
E
I
M
A
P
I
L
A
N
A
D
V
Q
E
R
L
L
P
Y
L
P
S
G
E
S
L
P
Q
T
A
D
E
I
---
Q
N
T
L
T
S
P
Q
F
Q
Q
A
L
G
M
F
S
A
A
L
A
S
G
Q
L
G
P
L
M
C
Q
F
G
L
P
A
E
A
V
E
A
A
N
K
G
D
V
E
A
F
A
K
A
M
Q
N
N
A
K
P
E
Q
K
E
G
D
T
K
D
K
K
D
E
E
E
D
M
S
L
D
7
PsiBlast_PDB
48.36
99%
-113
- C1 -
-
2L5V
-
ADRM1_HUMAN
A:
[259-407]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
Q
P
I
Q
L
S
D
L
Q
S
I
L
A
T
M
N
V
P
A
G
P
A
G
G
Q
Q
V
D
L
A
S
V
L
T
P
E
I
M
A
P
I
L
A
N
A
D
V
Q
E
R
L
L
P
Y
L
P
S
G
E
S
L
P
Q
T
A
D
E
I
---
Q
N
T
L
T
S
P
Q
F
Q
Q
A
L
G
M
F
S
A
A
L
A
S
G
Q
L
G
P
L
M
C
Q
F
G
L
P
A
E
A
V
E
A
A
N
K
G
D
V
E
A
F
A
K
A
M
Q
N
N
A
K
P
E
Q
K
E
G
D
T
K
D
K
K
D
E
E
E
D
M
S
L
D
37
HHSearch
47.12
100%
-145
- C1 -
-
5V1Y
-
ADRM1_HUMAN (first)
A:
[2-114]
------------------
S
N
K
Y
L
V
E
F
R
A
G
K
M
S
L
K
G
T
--
T
V
T
P
D
K
R
K
G
L
V
Y
I
Q
Q
T
D
D
S
---
L
I
H
F
C
W
K
D
R
T
S
G
N
----
V
E
D
D
L
I
I
F
P
D
D
C
E
F
K
R
V
P
Q
C
P
S
G
R
V
Y
V
L
K
F
K
A
G
S
K
R
L
F
F
W
M
Q
E
P
K
T
D
Q
D
E
E
H
C
R
K
V
N
E
Y
L
N
N
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
47.12
100%
-145
- C1 -
-
5V1Y
-
ADRM1_HUMAN (first)
A:
[2-114]
------------------
S
N
K
Y
L
V
E
F
R
A
G
K
M
S
L
K
G
T
--
T
V
T
P
D
K
R
K
G
L
V
Y
I
Q
Q
T
D
D
S
---
L
I
H
F
C
W
K
D
R
T
S
G
N
----
V
E
D
D
L
I
I
F
P
D
D
C
E
F
K
R
V
P
Q
C
P
S
G
R
V
Y
V
L
K
F
K
A
G
S
K
R
L
F
F
W
M
Q
E
P
K
T
D
Q
D
E
E
H
C
R
K
V
N
E
Y
L
N
N
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
46.60
100%
-128
- C1 -
-
5YMY
-
?
C:
[19-132]
------------------
S
N
K
Y
L
V
E
F
R
A
G
K
M
S
L
K
G
T
--
T
V
T
P
D
K
R
K
G
L
V
Y
I
Q
Q
T
D
D
S
---
L
I
H
F
C
W
K
D
R
T
S
G
N
----
V
E
D
D
L
I
I
F
P
D
D
C
E
F
K
R
V
P
Q
C
P
S
G
R
V
Y
V
L
K
F
K
A
G
S
K
R
L
F
F
W
M
Q
E
P
K
T
D
Q
D
E
E
H
C
R
K
V
N
E
Y
L
N
N
P
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
Fugue
46.49
98%
-142
- C1 -
-
2R2Y
-
ADRM1_MOUSE
A:
[22-130]
---------------------
Y
L
V
E
F
R
A
G
K
M
S
L
K
G
T
--
T
V
T
P
D
K
R
K
G
L
V
Y
I
Q
Q
T
D
D
S
---
L
I
H
F
C
W
K
D
R
T
S
G
T
----
V
E
D
D
L
I
I
F
P
D
D
C
E
F
K
R
V
P
Q
C
P
S
G
R
V
Y
V
L
K
F
K
A
G
S
K
R
L
F
F
W
M
Q
E
P
K
T
D
Q
D
E
E
H
C
R
K
V
N
E
C
L
N
N
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
46.47
96%
-142
- C1 -
-
2R2Y
-
ADRM1_MOUSE
A:
[22-130]
---------------------
Y
L
V
E
F
R
A
G
K
M
S
L
K
G
T
--
T
V
T
P
D
K
R
K
G
L
V
Y
I
Q
Q
T
D
D
S
---
L
I
H
F
C
W
K
D
R
T
S
G
T
----
V
E
D
D
L
I
I
F
P
D
D
C
E
F
K
R
V
P
Q
C
P
S
G
R
V
Y
V
L
K
F
K
A
G
S
K
R
L
F
F
W
M
Q
E
P
K
T
D
Q
D
E
E
H
C
R
K
V
N
E
C
L
N
N
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
45.96
100%
-140
- C1 -
-
5IRS
2
ADRM1_HUMAN
A:
[20-129]
--------------------
K
Y
L
V
E
F
R
A
G
K
M
S
L
K
G
T
--
T
V
T
P
D
K
R
K
G
L
V
Y
I
Q
Q
T
D
D
S
---
L
I
H
F
C
W
K
D
R
T
S
G
N
----
V
E
D
D
L
I
I
F
P
D
D
C
E
F
K
R
V
P
Q
C
P
S
G
R
V
Y
V
L
K
F
K
A
G
S
K
R
L
F
F
W
M
Q
E
P
K
T
D
Q
D
E
E
H
C
R
K
V
N
E
Y
L
N
N
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
45.95
100%
-140
- C1 -
-
2NBV
-
ADRM1_HUMAN
A:
[21-130]
--------------------
K
Y
L
V
E
F
R
A
G
K
M
S
L
K
G
T
--
T
V
T
P
D
K
R
K
G
L
V
Y
I
Q
Q
T
D
D
S
---
L
I
H
F
C
W
K
D
R
T
S
G
N
----
V
E
D
D
L
I
I
F
P
D
D
C
E
F
K
R
V
P
Q
C
P
S
G
R
V
Y
V
L
K
F
K
A
G
S
K
R
L
F
F
W
M
Q
E
P
K
T
D
Q
D
E
E
H
C
R
K
V
N
E
Y
L
N
N
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
45.85
100%
-137
- C1 -
-
5V1Z
-
ADRM1_HUMAN
A:
[3-114]
-------------------
N
K
Y
L
V
E
F
R
A
G
K
M
S
L
K
G
T
--
T
V
T
P
D
K
R
K
G
L
V
Y
I
Q
Q
T
D
D
S
---
L
I
H
F
C
W
K
D
R
T
S
G
N
----
V
E
D
D
L
I
I
F
P
D
D
C
E
F
K
R
V
P
Q
C
P
S
G
R
V
Y
V
L
K
F
K
A
G
S
K
R
L
F
F
W
M
Q
E
P
K
T
D
Q
D
E
E
H
C
R
K
V
N
E
Y
L
N
N
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
45.78
100%
-119
- C1 -
-
6CO4
-
ADRM1_HUMAN
A:
[24-136]
-------------------
N
K
Y
L
V
E
F
R
A
G
K
M
S
L
K
G
T
--
T
V
T
P
D
K
R
K
G
L
V
Y
I
Q
Q
T
D
D
S
---
L
I
H
F
C
W
K
D
R
T
S
G
N
----
V
E
D
D
L
I
I
F
P
D
D
C
E
F
K
R
V
P
Q
C
P
S
G
R
V
Y
V
L
K
F
K
A
G
S
K
R
L
F
F
W
M
Q
E
P
K
T
D
Q
D
E
E
H
C
R
K
V
N
E
Y
L
N
N
P
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
44.66
98%
-131
- C1 -
-
2Z59
-
ADRM1_MOUSE
A:
[22-130]
---------------------
Y
L
V
E
F
R
A
G
K
M
S
L
K
G
T
--
T
V
T
P
D
K
R
K
G
L
V
Y
I
Q
Q
T
D
D
S
---
L
I
H
F
C
W
K
D
R
T
S
G
T
----
V
E
D
D
L
I
I
F
P
D
D
C
E
F
K
R
V
P
Q
C
P
S
G
R
V
Y
V
L
K
F
K
A
G
S
K
R
L
F
F
W
M
Q
E
P
K
T
D
Q
D
E
E
H
C
R
K
V
N
E
C
L
N
N
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
Fugue
23.12
20%
-174
- C1 -
-
1SPF
-
?
?:
[1-35]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
R
I
P
C
C
P
-----
V
N
L
K
R
L
L
V
V
V
V
V
V
V
L
V
V
V
V
I
V
G
A
L
L
M
G
L
-------------------------------------------------------------------------------------------------
24
Fugue
22.21
25%
50
- C1 -
-
2Z4D
-
RPN13_YEAST
A:
[6-101]
---------------------
T
V
I
K
F
R
A
G
V
C
E
Y
N
E
D
SR
L
C
T
P
I
P
V
Q
G
E
I
E
I
K
P
N
E
E
E
ELG
F
W
D
F
E
W
R
P
T
E
K
P
V
GREL
D
P
I
S
L
I
L
I
P
G
E
T
M
W
V
P
I
K
S
S
K
S
G
R
I
F
A
L
V
F
S
-
S
N
E
R
Y
F
F
W
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
41
HHSearch
21.41
21%
-15
- C1 -
-
6HGC
-
?
C:
[13-96]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
T
N
L
R
A
L
L
N
K
Q
T
F
S
L
L
P
P
--
L
Y
Q
Y
N
L
I
Q
L
L
P
S
V
D
R
E
A
S
E
-
E
A
I
RLS
A
S
C
L
N
N
E
F
F
A
R
A
C
L
E
W
R
E
R
L
S
E
G
E
F
T
P
-----------------------------------------------------
16
PsiBlast_PDB
18.58
100%
-
- C1 -
-
4WLQ
-
ADRM1_HUMAN
B:
[286-384]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
D
L
A
S
V
L
T
P
E
I
M
A
P
I
L
A
N
A
D
V
Q
E
R
L
L
P
Y
L
P
S
G
E
S
L
P
Q
T
A
D
E
I
---
Q
N
T
L
T
S
P
Q
F
Q
Q
A
L
G
M
F
S
A
A
L
A
S
G
Q
L
G
P
L
M
C
Q
F
G
L
P
A
E
A
V
E
A
A
N
K
G
D
V
E
A
F
A
K
A
M
Q
N
N
-----------------------