@TOME V3
(Feb 2022)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
3D Alignment Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
3D Alignment Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
PDB Ligands
Affinity Score
Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
Sequence Alignment
Tab of Complexes
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : ARGL1_HUMAN: (2020-01-31 )
MGRSRSRSSSRSKHTKSSKHNKKRSRSRSRSRDKERVRKRSKSRESKRNRRRESRSRSRSTNTAVSRRERDRERASSPPDRIDIFGRTVSKRSSLDEKQKREEEEKKAEFERQRKIRQQEIEEKLIEEETARRVEELVAKRVEEELEKRKDEIEREVLRRVEEAKRIMEKQLLEELERQRQAELAAQKAREEEERAKREELERILEENNRKIAEAQAKLAEEQLRIVEEQRKIHEERMKLEQERQRQQKEEQKIILGKGKSRPKLSFSLKTQD
Atome Classification :
(20 SA)
.........10........20........30........40........50.-.......60........70........80........90........100.....-..110.......120....-----...130-.......140-----.......150....--.....160.......170........180..-----------------.....190-----....-------------------.....200......-------.210.-.------.....220......-.230...-----....240.......250...-....260.......270.
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MGRSRSRSSSRSKHTKSSKH
N
K
K
R
S
RSRSRSR
D
K
E
R
V
R
K
R
SK
S
R
E
S
K
R
N
R
R
R
-
E
S
RSRSRSTN
T
A
V
S
R
R
E
R
D
R
E
RASSPPD
R
I
D
I
F
G
R
T
V
S
KRSS
L
D
E
K
Q
K
R
E
E
E
E
K
K
-
A
E
F
E
R
Q
R
K
I
R
Q
Q
E
I
E
E
K
L
I
-----
E
E
E
T
A
R
-
R
V
E
E
L
V
A
K
R
V
-----
E
E
E
L
E
K
R
K
--
D
E
I
E
--
R
E
V
L
R
R
V
E
E
A
K
R
I
M
E
K
-
Q
L
L
E
E
L
E
R
Q
R
Q
A
E
L
-----------------
A
A
Q
K
A
R
-------
E
E
E
E
-------------------
R
A
K
R
E
E
L
E
R
I
L
E
EN-------N
R
K
I
A
-
E
------
A
Q
A
K
L
A
E
E
Q
L
R
I
V
E
-
E
Q
R
K
I
H
E
-----
E
R
M
K
L
E
Q
E
R
Q
R
Q
Q
K
E
EQ
K
I
I
-LGKGKSR
P
K
L
S
F
S
L
KTQD
24
Fugue
58.87
23%
94
- C2 -
-
5SZH
-
A:
[1-148]
---------------------------------------------------------------------------------------------------------
G
H
M
-
K
Q
E
E
L
K
R
L
Y
K
A
Q
A
I
Q
R
Q
L
E
-----
E
V
E
E
R
Q
-
R
A
S
E
I
Q
G
V
R
L
-----
E
K
A
L
R
G
E
Q
--
D
------
E
A
Q
L
L
Q
E
W
F
K
L
V
L
E
K
-
N
K
L
M
R
Y
E
S
E
L
L
I
M
A
-----------------
Q
E
L
E
L
E
-------
D
H
Q
S
-------------------
R
L
E
Q
K
L
R
E
K
M
L
K
E
E
-------
S
Q
K
-----------
D
E
K
D
L
N
E
E
Q
E
V
F
T
-
E
L
M
Q
V
I
E
-----
Q
R
D
K
L
V
D
S
L
E
E
Q
R
I
R
E
K
A
E
D
-------------------
23
Fugue
56.11
16%
98
- C2 -
-
5MQF
-
SPF27_HUMAN
K:
[13-225]
---------------------
V
D
A
L
P
Y
F
D
Q
G
Y
E
A
P
G
V
R
E
A
A
A
A
L
V
E
E
E
T
R
R
---------------
Y
R
P
T
K
N
Y
L
S
Y
L
T
A
P
D
Y
-----------
S
A
F
E
T
D
I
M
R
N
E
F
E
R
L
-
A
A
--------
R
Q
P
I
A
W
Q
E
C
-----
V
N
N
S
M
A
-
Q
L
E
H
Q
A
V
R
I
E
-----
N
L
E
L
M
S
Q
H
--
G
C
------------
N
A
W
K
V
Y
N
E
-
N
L
V
H
M
I
E
H
A
-
Q
K
E
L
-----------------
Q
K
L
R
K
H
-------
I
Q
D
L
-------------------
N
W
Q
R
K
N
M
Q
L
T
A
G
S
K
-------
L
R
E
M
E
-
S
------
N
W
V
S
L
V
S
K
N
Y
E
I
E
R
-
T
I
V
Q
L
E
N
-----
E
I
Y
Q
I
K
Q
Q
H
G
E
A
N
K
E
N
I
R
Q
D
-
F
-----------------
13
PsiBlast_PDB
55.51
22%
158
- C2 -
-
4GNK
-
PLCB3_HUMAN
B:
[78-872]
-----------------------------------------
K
L
R
S
R
Q
E
R
D
L
R
-
E
L
R
K
K
H
Q
R
K
A
V
T
L
T
R
R
L
L
D
G
L
A
Q
A
Q
A
E
G
R
C
R
L
R
P
G
A
L
G
G
A
A
D
V
E
D
T
K
E
G
E
D
E
A
K
R
Y
Q
E
F
Q
N
R
Q
V
Q
S
L
L
E
L
R
E
A
Q
V
-----
D
A
E
A
Q
R
-
R
L
E
H
L
N
I
R
Q
A
-----
L
Q
R
L
R
E
V
V
--
L
D
A
N
--
T
T
Q
F
K
R
L
K
E
M
N
E
R
E
K
K
-
E
L
Q
K
I
L
D
R
K
R
H
N
S
I
-----------------
S
E
A
K
M
R
-------
D
K
H
K
---------------------
K
E
A
E
L
T
E
I
---
N
-------
R
R
H
I
T
-
E
------
S
V
N
S
I
R
----
R
L
E
E
-
A
Q
K
Q
R
H
D
-----
R
L
V
A
G
Q
Q
Q
V
L
Q
Q
L
A
E
E
E
P
K
L
-
L
A
Q
---------------
18
PsiBlast_PDB
54.03
21%
168
- C2 -
-
6BK8
-
PRP22_YEAST
P:
[514-1135]
----------------------------------------------
K
R
N
T
E
S
V
E
D
R
G
R
S
N
D
A
H
T
S
R
N
M
K
N
K
I
K
R
R
A
L
T
S
P
E
R
W
E
I
R
Q
L
I
A
S
G
A
A
S
I
D
D
---------
Y
-
P
E
L
K
D
E
I
P
I
N
T
S
Y
L
T
A
K
R
D
-----
D
G
S
I
V
N
-
G
N
T
E
K
V
D
S
K
L
-----
E
E
Q
Q
R
D
E
T
--
D
E
I
D
--
V
E
L
--
N
T
D
D
G
P
K
F
L
K
D
-
Q
Q
V
K
G
A
K
K
Y
E
M
P
K
I
TKVPRGFMNRSAINGSN
A
I
R
D
H
R
-------
E
E
K
L
-------------------
R
K
K
R
E
I
E
Q
Q
I
R
K
Q
Q
SFDDPTK
N
K
K
D
S
-
R
------
N
E
I
Q
M
L
K
N
Q
L
I
V
T
E
W
E
K
N
R
M
N
E
SISYG
K
R
T
S
L
P
I
S
A
Q
R
Q
---------------------------
26
Fugue
52.42
24%
24
- C2 -
-
4WHE
1
PSPA_ECOLI
A:
[3-142]
--------------------------------------------------------------------------------------------------------------
I
F
S
R
F
A
D
I
V
N
A
N
I
N
A
L
L
--------
E
D
P
Q
-
K
L
V
R
L
M
I
Q
E
M
-----
E
D
T
L
V
E
V
R
--
S
T
S
A
--
R
A
L
A
E
K
K
Q
L
T
R
R
I
-
E
Q
-
A
S
A
R
E
V
E
W
Q
E
K
A
E
L
-----------------
A
L
L
K
----------------------------------
E
R
E
D
L
A
R
A
A
L
I
E
-------
K
Q
K
L
T
-
D
------
L
I
K
S
L
E
H
E
V
T
L
V
D
D
-
T
L
A
R
M
K
K
-----
E
I
G
E
L
E
N
K
L
S
E
T
R
A
R
Q
Q
A
L
M
-
L
R
----------------
17
PsiBlast_PDB
50.78
21%
168
- C2 -
-
6EXN
-
PRP22_YEAST
V:
[514-1099]
----------------------------------------------
K
R
N
T
E
S
V
E
D
R
G
R
S
N
D
A
H
T
S
R
N
M
K
N
K
I
K
R
R
A
L
T
S
P
E
R
W
E
I
R
Q
L
I
A
S
G
A
A
S
I
D
D
---------
Y
-
P
E
L
K
D
E
I
P
I
N
T
S
Y
L
T
A
K
R
D
-----
D
G
S
I
V
N
-
G
N
T
E
K
V
D
S
K
L
-----
E
E
Q
Q
R
D
E
T
--
D
E
I
D
--
V
E
L
--
N
T
D
D
G
P
K
F
L
K
D
-
Q
Q
V
K
G
A
K
K
Y
E
M
P
K
I
TKVPRGFMNRSAINGSN
A
I
R
D
H
R
-------
E
E
K
L
-------------------
R
K
K
R
E
I
E
Q
Q
I
R
K
Q
Q
SFDDPTK
N
K
K
D
S
-
R
------
N
E
I
Q
M
L
K
N
Q
L
I
V
T
E
W
E
K
N
R
M
N
E
SISYG
K
R
T
S
L
P
I
S
A
Q
R
Q
---------------------------
16
PsiBlast_PDB
50.61
21%
171
- C2 -
-
5MQ0
-
PRP22_YEAST
V:
[514-1124]
----------------------------------------------
K
R
N
T
E
S
V
E
D
R
G
R
S
N
D
A
H
T
S
R
N
M
K
N
K
I
K
R
R
A
L
T
S
P
E
R
W
E
I
R
Q
L
I
A
S
G
A
A
S
I
D
D
---------
Y
-
P
E
L
K
D
E
I
P
I
N
T
S
Y
L
T
A
K
R
D
-----
D
G
S
I
V
N
-
G
N
T
E
K
V
D
S
K
L
-----
E
E
Q
Q
R
D
E
T
--
D
E
I
D
--
V
E
L
--
N
T
D
D
G
P
K
F
L
K
D
-
Q
Q
V
K
G
A
K
K
Y
E
M
P
K
I
TKVPRGFMNRSAINGSN
A
I
R
D
H
R
-------
E
E
K
L
-------------------
R
K
K
R
E
I
E
Q
Q
I
R
K
Q
Q
SFDDPTK
N
K
K
D
S
-
R
------
N
E
I
Q
M
L
K
N
Q
L
I
V
T
E
W
E
K
N
R
M
N
E
SISYG
K
R
T
S
L
P
I
S
A
Q
R
Q
---------------------------
12
PsiBlast_PDB
50.22
28%
206
- C2 -
-
5YFP
-
SEC3_YEAST
A:
[643-1332]
------------------------------------------
S
A
P
T
E
R
T
R
R
S
-
E
T
E
S
V
N
P
V
S
T
P
A
S
V
E
Y
H
A
G
M
K
S
L
N
K
A
P
Y
S
S
N
S
T
L
N
E
V
N
K
R
Y
E
L
E
Q
Q
Q
Q
Q
E
E
A
E
L
R
-
R
L
E
E
Q
K
R
L
Q
L
Q
K
E
N
E
M
K
R
L
-----
E
E
E
-----------
R
R
I
-----
K
Q
E
E
R
K
R
Q
--
M
E
L
E
--
H
Q
R
Q
L
E
E
E
E
R
K
R
Q
M
E
-------
L
E
A
K
K
Q
M
E
L
-----------------
K
R
Q
R
Q
F
-------
E
E
E
Q
-------------------
R
L
K
K
E
R
E
L
L
E
I
Q
R
K
-------
Q
R
E
Q
E
-
T
------
A
E
R
L
K
K
E
E
Q
E
A
L
A
K
-
K
E
E
E
E
K
S
-----
K
R
N
K
V
D
N
E
S
Y
T
Q
E
--------------------------
37
Fugue
44.47
24%
-186
- C2 -
-
2YF2
9
?
A:
[7-63]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
D
V
C
G
E
V
A
-------
Y
I
Q
S
V
-
V
------
S
D
C
H
V
P
T
E
D
V
K
T
L
L
-
E
I
R
K
L
F
L
-----
E
I
Q
K
L
K
V
E
L
Q
G
L
S
K
E
F
L
E
H
I
-
L
H
----------------
14
PsiBlast_PDB
44.29
25%
169
- C2 -
-
6FML
-
?
J:
[291-724]
------------------------------------------------------------------------------------------------------
E
D
R
E
R
I
-
V
Q
Y
P
Y
T
E
E
V
V
V
Q
K
T
E
E
E
L
A
RIAER
K
K
E
S
G
R
-
R
L
Q
E
Q
A
A
K
M
R
-----
L
E
R
L
M
K
K
E
--
Q
E
L
E
YY
K
D
I
Q
R
R
M
Q
G
E
S
K
K
E
I
K
-
R
L
L
D
E
A
E
L
K
D
E
A
A
L
------------------
E
R
V
I
R
-------
D
L
E
R
-------------------
S
I
K
R
A
R
Q
K
D
L
G
E
P
E
-------
E
E
E
V
P
-
D
FSLLDV
P
D
D
Q
L
D
E
A
G
L
R
Q
K
R
-
Q
Q
R
------------------------------------------------
15
PsiBlast_PDB
43.74
26%
182
- C2 -
-
6FHS
1
?
J:
[75-764]
------------------------------------------------------------------------------------------------------
E
D
R
E
R
I
-
V
Q
Y
P
Y
T
E
E
V
V
V
Q
K
T
E
E
E
L
A
RIAER
K
K
E
S
G
R
-
R
L
Q
E
Q
A
A
K
M
R
-----
L
E
R
L
M
K
K
E
--
Q
E
L
E
YY
K
D
I
Q
R
R
M
Q
G
E
S
K
K
E
I
K
-
R
L
L
D
E
A
E
L
K
D
E
A
A
L
ERVIRDLER--------
S
I
K
R
A
R
QKDLGEP
E
E
E
E
VPDFSLLDVPDDQLDEAGL
R
Q
K
R
Q
--
Q
R
L
L
K
S
N
-------
W
E
A
R
Q
-
R
------
A
K
A
E
K
E
A
E
K
A
R
L
A
E
-
E
A
R
-
L
D
E
-----
E
R
R
K
N
D
L
E
G
W
L
E
E
K
R
Q
L
R
L
A
K
L
N
Q
L
K
E
R
E
R
L
K
A
D
-----
5
PsiBlast_PDB
43.52
28%
-69
- C2 -
-
4K7K
-
CUSC_ECOLI
A:
[120-188]
---------------------------------------------------------------------------------------------------------------
F
G
R
L
K
N
M
S
E
A
E
R
Q
N
Y
L
A
-----
T
E
E
A
Q
R
-
A
V
H
I
L
L
V
S
N
V
AQSYF
N
Q
Q
L
A
Y
A
Q
--
L
Q
I
A
--
E
E
T
L
R
N
Y
Q
Q
S
Y
A
F
V
E
K
-
Q
L
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
43.04
23%
110
- C2 -
-
6MZM
-
TAF4_HUMAN
D:
[839-943]
-----------------------------------------------------------------------------------------
V
S
Y
V
S
H
A
T
Q
Q
R
L
Q
N
L
V
E
K
I
-
S
E
T
A
Q
Q
K
N
F
S
Y
K
D
--
D
D
R
Y
-----
E
Q
A
S
D
V
-
R
A
Q
L
K
F
F
E
Q
L
-----
D
Q
I
E
K
Q
R
K
--
D
E
Q
E
--
R
E
I
L
M
R
A
A
K
-------L
R
L
K
Q
K
A
K
E
M
Q
Q
Q
E
L
-----------------
A
Q
M
R
Q
R
-------
D
--------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
42.90
28%
-73
- C2 -
-
4K34
-
CUSC_ECOLI
A:
[120-188]
---------------------------------------------------------------------------------------------------------------
F
G
R
L
K
N
M
S
E
A
E
R
Q
N
Y
L
A
-----
T
E
E
A
Q
R
-
A
V
H
I
L
L
V
S
N
V
AQSYF
N
Q
Q
L
A
Y
A
Q
--
L
Q
I
A
--
E
E
T
L
R
N
Y
Q
Q
S
Y
A
F
V
E
K
-
Q
L
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
Fugue
41.52
25%
-127
- C2 -
-
5TOH
-
VP35_MABVM
A:
[1-52]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
D
I
-------
I
W
D
Q
-------------------
L
I
V
K
R
T
L
A
D
L
L
I
P
I
-------
N
R
Q
I
S
-
D
------
I
Q
S
T
L
S
E
V
T
T
R
V
H
E
-
I
E
R
Q
L
H
E
-----
I
T
P
V
-----------------------------------
33
Fugue
38.81
17%
11
- C2 -
-
2JEE
-
ZAPB_ECOLI
A:
[3-80]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
S
L
-
E
V
F
E
K
L
E
A
K
V
Q
Q
A
I
-----------------
D
T
I
T
L
L
-------
Q
M
E
I
-------------------
E
E
L
K
E
K
-
N
N
S
L
S
Q
E
-------
V
Q
N
A
Q
-
H
------
Q
R
E
E
L
E
R
E
N
N
H
L
K
E
-
Q
Q
N
G
W
Q
E
-----
R
L
Q
A
L
L
G
R
M
E
E
----------------------------
36
Fugue
38.48
18%
36
- C2 -
-
5J0H
-
?
A:
[7-78]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
Y
E
L
R
R
A
L
E
E
L
E
-----------------
K
A
L
R
E
L
-------
K
K
S
L
-------------------
D
E
L
E
R
S
L
E
E
L
E
K
N
P
-------
S
E
D
A
L
-
V
------
E
N
N
R
L
N
V
E
N
N
K
I
I
V
-
E
V
L
R
I
I
A
-----
E
V
L
K
I
N
A
K
S
------------------------------
4
PsiBlast_PDB
36.04
28%
76
- C2 -
-
3PIK
1
CUSC_ECOLI
A:
[120-188]
---------------------------------------------------------------------------------------------------------------
F
G
R
L
K
N
M
S
E
A
E
R
Q
N
Y
L
A
-----
T
E
E
A
Q
R
-
A
V
H
I
L
L
V
S
N
V
AQSYF
N
Q
Q
L
A
Y
A
Q
--
L
Q
I
A
--
E
E
T
L
R
N
Y
Q
Q
S
Y
A
F
V
E
K
-
Q
L
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
35.79
28%
88
- C2 -
-
4K7R
1
CUSC_ECOLI
A:
[120-188]
---------------------------------------------------------------------------------------------------------------
F
G
R
L
K
N
M
S
E
A
E
R
Q
N
Y
L
A
-----
T
E
E
A
Q
R
-
A
V
H
I
L
L
V
S
N
V
AQSYF
N
Q
Q
L
A
Y
A
Q
--
L
Q
I
A
--
E
E
T
L
R
N
Y
Q
Q
S
Y
A
F
V
E
K
-
Q
L
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
Fugue
35.78
18%
104
- C2 -
-
5IR0
-
?
A:
[1-127]
------------------------------------------------------------------------------------------------------------------------------------------
G
M
Y
T
N
T
I
I
K
T
E
I
-----
D
E
K
V
I
K
A
F
KL
D
A
L
T
--
R
S
K
L
F
F
K
L
T
T
K
L
A
V
P
F
-
H
L
D
Q
E
T
F
E
E
T
Q
L
I
L
-----------------
F
G
S
I
V
E
-------
D
G
E
A
-------------------
L
A
T
P
E
A
I
N
K
W
F
E
Y
N
-------
D
V
N
-
P
M
D
------
L
F
V
W
L
V
D
E
N
L
V
T
L
F
-
K
G
-------------------------------------------------