@TOME V3
(Feb 2022)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
3D Alignment Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
3D Alignment Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
PDB Ligands
Affinity Score
Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
Sequence Alignment
Tab of Complexes
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : CD47_HUMAN: (2020-01-31 )
MWPLVAALLLGSACCGSAQLLFNKTKSVEFTFCNDTVVIPCFVTNMEAQNTTEVYVKWKFKGRDIYTFDGALNKSTVPTDFSSAKIEVSQLLKGDASLKMDKSDAVSHTGNYTCEVTELTREGETIIELKYRVVSWFSPNENILIVIFPIFAILLFWGQFGIKTLKYRSGGMDEKTIALLVAGLVITVIVIVGAILFVPGEYSLKNATGLGLIVTSTGILILLHYYVFSTAIGLTSFVIAILVIQVIAYILAVVGLSLCIAACIPMHGPLLISGLSILALAQLLGLVYMKFVASNQKTIQPPRKAVEEPLNAFKESKGMMNDE
Atome Classification :
(20 SA)
.........10........20........30........40........50........60.-------......-.-.70.-.......80.-.....-..90........100-........110.......120...-...-.130...-----....140.......150---.........160-.......170.......180.....----..190.......200.......210.......220.......230----.......240.......250---.......260.......270.......280.......290.......300-------.......310.......320.
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
M
W
P
L
V
A
A
L
L
LGSACCG
S
A
Q
L
L
FNKTK
S
V
E
F
T
FCND
T
V
V
I
P
C
F
VTNMEAQNT
T
E
V
Y
V
K
W
K
F-K-------G
R
D
I
Y
T
-F-DGAL-NKSTVPTDFS-S
A
K
I
E
-
V
S
Q
L
LKGDASLKMD--KSDAVSHTG
N
Y
T
C
E
V
TELTREG
E
T
-
I
I
E
-
L
K
Y
R
V
V
S
-----
W
FSPNE
N
I
L
I
V
I
F
P
I
-----
F
A
I
L
L
F
W
G
QFG
I
-
K
T
L
K
YRSGGMD
E
K
T
I
A
L
L
V
A
G
L
V
I
T
----
V
I
V
I
V
G
A
I
LFVPGEYSLKNATG
L
G
L
I
V
TST
G
I
L
I
L
L
H
Y
Y
V
F
S
T
A
I
----
G
L
T
S
F
V
I
A
I
L
V
I
Q
V
I
A
Y
I
L
A
---
V
V
G
L
S
L
C
I
A
A
C
IPMH
G
P
L
L
I
S
G
L
S
I
L
A
L
A
Q
L
L
G
L
V
Y
M
K
F
V
ASNQKTIQP
P
-------
R
K
A
V
E
E
P
L
N
A
F
K
E
SKGMMNDE
8
PsiBlast_PDB
94.02
99%
-122
- C3 -
-
4KJY
3
CD47_HUMAN
A:
[2-114]
-------------------
L
L
F
N
K
T
K
S
V
E
F
T
F
G
N
D
T
V
V
I
P
C
F
V
T
N
M
E
A
Q
N
T
T
E
V
Y
V
K
W
K
F
-
K
-------
G
R
D
I
Y
T
-
F
-
D
G
A
L
-
N
K
S
T
V
P
T
D
F
S
-
S
A
K
I
E
-
V
S
Q
L
L
K
G
D
A
S
L
K
M
D
--
K
S
D
A
V
S
H
T
G
N
Y
T
C
E
V
T
E
L
T
R
E
G
E
T
-
I
I
E
-
L
K
Y
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
93.08
94%
-130
- C3 -
-
2VSC
5
CD47_HUMAN
A:
[2-115]
-------------------
L
L
F
N
K
T
K
S
V
E
F
T
F
G
N
D
T
V
V
I
P
C
F
V
T
N
M
E
A
Q
N
T
T
E
V
Y
V
K
W
K
F
-
K
-------
G
R
D
I
Y
T
-
F
-
D
G
A
L
-
N
K
S
T
V
P
T
D
F
S
-
S
A
K
I
E
-
V
S
Q
L
L
K
G
D
A
S
L
K
M
D
--
K
S
D
A
V
S
H
T
G
N
Y
T
C
E
V
T
E
L
T
R
E
G
E
T
-
I
I
E
-
L
K
Y
R
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
92.96
98%
-110
- C3 -
-
5TZU
6
CD47_HUMAN
C:
[1-115]
------------------
Q
L
L
F
N
K
T
K
S
V
E
F
T
F
G
N
D
T
V
V
I
P
C
F
V
T
N
M
E
A
Q
N
T
T
E
V
Y
V
K
W
K
F
-
K
-------
G
R
D
I
Y
T
-
F
-
D
G
A
L
-
N
K
S
T
V
P
T
D
F
S
-
S
A
K
I
E
-
V
S
Q
L
L
K
G
D
A
S
L
K
M
D
--
K
S
D
A
V
S
H
T
G
N
Y
T
C
E
V
T
E
L
T
R
E
G
E
T
-
I
I
E
-
L
K
Y
R
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
41
Fugue
92.11
99%
-118
- C3 -
-
2JJS
3
CD47_HUMAN
C:
[2-116]
-------------------
L
L
F
N
K
T
K
S
V
E
F
T
F
G
N
D
T
V
V
I
P
C
F
V
T
N
M
E
A
Q
N
T
T
E
V
Y
V
K
W
K
F
-
K
-------
G
R
D
I
Y
T
-
F
-
D
G
A
L
-
N
K
S
T
V
P
T
D
F
S
-
S
A
K
I
E
-
V
S
Q
L
L
K
G
D
A
S
L
K
M
D
--
K
S
D
A
V
S
H
T
G
N
Y
T
C
E
V
T
E
L
T
R
E
G
E
T
-
I
I
E
-
L
K
Y
R
V
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
91.02
94%
-118
- C3 -
-
2JJS
3
CD47_HUMAN
C:
[2-116]
-------------------
L
L
F
N
K
T
K
S
V
E
F
T
F
G
N
D
T
V
V
I
P
C
F
V
T
N
M
E
A
Q
N
T
T
E
V
Y
V
K
W
K
F
-
K
-------
G
R
D
I
Y
T
-
F
-
D
G
A
L
-
N
K
S
T
V
P
T
D
F
S
-
S
A
K
I
E
-
V
S
Q
L
L
K
G
D
A
S
L
K
M
D
--
K
S
D
A
V
S
H
T
G
N
Y
T
C
E
V
T
E
L
T
R
E
G
E
T
-
I
I
E
-
L
K
Y
R
V
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
90.94
94%
-115
- C3 -
-
2JJT
3
CD47_HUMAN
C:
[2-115]
-------------------
L
L
F
N
K
T
K
S
V
E
F
T
F
G
N
D
T
V
V
I
P
C
F
V
T
N
M
E
A
Q
N
T
T
E
V
Y
V
K
W
K
F
-
K
-------
G
R
D
I
Y
T
-
F
-
D
G
A
L
-
N
K
S
T
V
P
T
D
F
S
-
S
A
K
I
E
-
V
S
Q
L
L
K
G
D
A
S
L
K
M
D
--
K
S
D
A
V
S
H
T
G
N
Y
T
C
E
V
T
E
L
T
R
E
G
E
T
-
I
I
E
-
L
K
Y
R
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
90.70
98%
-103
- C3 -
-
5TZ2
5
CD47_HUMAN
C:
[1-114]
------------------
Q
L
L
F
N
K
T
K
S
V
E
F
T
F
G
N
D
T
V
V
I
P
C
F
V
T
N
M
E
A
Q
N
T
T
E
V
Y
V
K
W
K
F
-
K
-------
G
R
D
I
Y
T
-
F
-
D
G
A
L
-
N
K
S
T
V
P
T
D
F
S
-
S
A
K
I
E
-
V
S
Q
L
L
K
G
D
A
S
L
K
M
D
--
K
S
D
A
V
S
H
T
G
N
Y
T
C
E
V
T
E
L
T
R
E
G
E
T
-
I
I
E
-
L
K
Y
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
89.06
98%
-105
- C3 -
-
5IWL
4
CD47_HUMAN
C:
[2-114]
-------------------
L
L
F
N
K
T
K
S
V
D
F
T
F
G
N
D
T
V
V
I
P
C
F
V
T
N
M
E
A
Q
N
T
T
E
V
Y
V
K
W
K
F
-
K
-------
G
R
D
I
Y
T
-
F
-
D
G
A
L
-
N
K
S
T
V
P
T
D
F
S
-
S
A
K
I
E
-
V
S
Q
L
L
K
G
D
A
S
L
K
M
D
--
K
S
D
A
V
S
H
T
G
N
Y
T
C
E
V
T
E
L
T
R
E
G
E
T
-
I
I
E
-
L
K
Y
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
88.97
98%
-126
- C3 -
-
5TZT
1
CD47_HUMAN
C:
[2-111]
-------------------
L
L
F
N
K
T
K
S
V
E
F
T
F
G
N
D
T
V
V
I
P
C
F
V
T
N
M
E
A
Q
N
T
T
E
V
Y
V
K
W
K
F
-
K
-------
G
R
D
I
Y
T
-
F
-
D
G
A
L
-
N
K
S
T
V
P
T
D
F
S
-
S
A
K
I
E
-
V
S
Q
L
L
K
G
D
A
S
L
K
M
D
--
K
S
D
A
V
S
H
T
G
N
Y
T
C
E
V
T
E
L
T
R
E
G
E
T
-
I
I
E
-
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
88.63
94%
-114
- C3 -
-
4CMM
4
CD47_HUMAN
B:
[2-120]
-------------------
L
L
F
N
K
T
K
S
V
E
F
T
F
G
N
D
T
V
V
I
P
C
F
V
T
N
M
E
A
Q
N
T
T
E
V
Y
V
K
W
K
F
-
K
-------
G
R
D
I
Y
T
-
F
-
D
G
A
L
-
N
K
S
T
V
P
T
D
F
S
-
S
A
K
I
E
-
V
S
Q
L
L
K
G
D
A
S
L
K
M
D
--
K
S
D
A
V
S
H
T
G
N
Y
T
C
E
V
T
E
L
T
R
E
G
E
T
-
I
I
E
-
L
K
Y
R
V
V
S
-----
W
S
T
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
56
Fugue
55.09
15%
-75
- C1 -
-
1SLQ
-
VP4_ROTRH
A:
[253-522]
------------------
D
I
V
V
S
K
T
S
L
W
K
E
M
Q
Y
N
R
D
I
T
I
R
F
K
F
A
S
S
I
V
K
S
G
G
L
G
Y
-----------------------------------
K
W
S
-
E
I
S
F
K
--------------------
P
A
N
Y
Q
Y
T
Y
T
R
D
G
E
E
V
T
A
H
T
T
C
-
S
V
N
G
M
N
D
F
N
F
N
-----
G
G
S
L
P
T
D
F
V
I
S
R
Y
E
V
IKENS
Y
V
Y
V
D
Y
W
D
D
S
Q
A
F
R
N
M
V
Y
-----------------
V
R
S
----
L
A
A
N
L
N
S
V
I
C
T
G
G
D
Y
S
F
A
L
P
V
G
Q
W
P
V
M
T
G
G
A
V
S
L
H
S
A
G
V
T
L
S
T
Q
F
TDFV
S
L
N
S
L
R
F
R
F
R
L
T
V
E
E
P
S
F
S
I
TRT
R
V
S
R
L
Y
G
L
P
A
A
N
P
N
N
G
K
---------
E
Y
Y
E
V
A
G
R
F
S
L
I
S
L
V
P
S
N
D
D
Y
Q
T
P
ITNSVTV
R
Q
D
L
E
R
Q
L
G
E
L
R
E
E
F
N
A
L
S
Q
E
45
Fugue
52.83
15%
-82
- C3 -
-
5J8O
1
PD1L1_HUMAN
A:
[1-122]
------------------
A
F
T
V
T
V
P
K
D
L
Y
V
V
E
Y
G
S
N
M
T
I
E
C
K
F
P
V
E
K
Q
L
D
L
A
A
L
I
V
Y
W
E
M
-
E
-------
D
K
N
I
I
Q
-
F
V
H
G
E
E
-
D
L
K
V
Q
H
S
S
Y
R
Q
R
A
R
L
L
-
K
D
Q
L
S
L
G
N
A
A
L
Q
I
T
--
D
V
K
-
L
Q
D
A
G
V
Y
R
C
M
I
S
Y
---
G
G
A
D
-
Y
K
R
-
I
T
V
K
V
N
A
-----
P
Y
A
A
A
L
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
52
Fugue
49.68
12%
-118
* C2 *
-
5HAM
-
?
A:
[6-265]
D
Y
W
Y
T
E
N
E
I
T
H
L
L
T
A
Q
L
D
E
K
K
F
S
V
Q
P
A
I
T
F
R
N
-----------
T
A
L
T
E
E
M
L
K
D
Y
T
A
K
G
E
E
-
K
-------
N
K
I
L
A
E
-
V
-
Q
E
T
I
-
K
I
A
N
L
I
P
D
K
E
-
E
R
A
L
M
-
L
G
D
A
K
K
R
E
E
I
L
K
L
S
--
D
A
E
R
E
K
L
K
N
D
L
L
R
G
G
E
A
Q
Q
Q
I
N
E
D
-
I
L
N
-
R
A
T
K
D
I
K
-----
D
N
G
K
E
----
A
A
V
I
P
I
-----
E
M
G
Y
G
H
W
T
V
L
V
A
-
K
Y
D
K
------
K
D
N
Q
I
I
L
T
F
N
D
S
L
G
N
----
S
I
N
Y
D
G
Q
K
L
P
K
L
I
D
K
T
L
G
N
L
P
N
K
P
I
I
I
D
E
------------
Q
T
K
Q
----
Q
T
D
Q
S
A
C
G
V
F
T
V
D
N
G
I
K
I
A
------------------------
K
G
Q
A
I
L
S
T
E
E
S
K
G
E
K
G
L
R
L
R
E
H
H
A
Q
I
L
T
D
----------------
A
M
F
K
Q
D
A
Q
W
I
R
Q
Q
47
Fugue
47.36
19%
-54
- C3 -
-
1Z9M
-
CADM3_HUMAN
A:
[38-141]
------------------
Q
D
D
S
Q
P
W
T
S
D
E
T
V
V
A
G
G
T
V
V
L
K
C
Q
V
K
D
H
E
D
S
S
-----
L
Q
W
S
N
-
P
-------
A
Q
Q
T
L
Y
-
F
-
G
E
K
R
-
A
L
R
--------
D
N
R
I
Q
-
L
V
T
S
T
P
H
E
L
S
I
S
I
S
--
N
V
A
-
L
A
D
E
G
E
Y
T
C
S
I
F
-----
T
M
P
-
V
R
T
-
A
K
S
L
V
T
V
-----
L
G
I
P
Q
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
43
Fugue
47.09
18%
28
- C3 -
-
1KAC
-
CXAR_HUMAN
B:
[23-146]
--------------------
G
I
T
T
P
E
E
M
I
E
K
A
K
G
E
T
A
Y
L
P
C
K
F
T
L
-
S
P
E
D
Q
G
P
L
D
I
E
W
L
I
-
S
PADNQKV
D
Q
V
I
I
L
-
Y
-
S
G
D
K
-
I
Y
D
D
Y
Y
P
D
L
K
G
R
V
H
F
T
-
S
N
D
L
K
S
G
D
A
S
I
N
V
T
--
N
L
Q
-
L
S
D
I
G
T
Y
Q
C
K
V
K
K
A
P
G
V
A
N
K
-
K
I
H
-
L
V
V
L
V
K
P
-----
S
G
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
45.24
32%
-27
- C3 -
-
5IMK
-
VSIG4_HUMAN
A:
[25-117]
------------------------------------
V
N
L
P
C
--
T
Y
D
P
L
Q
G
Y
T
Q
V
L
V
K
W
L
V
Q
R
-------
G
S
D
P
V
T
I
F
-
L
R
D
S
-
S
G
D
H
I
Q
Q
A
K
Y
-
Q
G
R
L
H
-
V
S
H
K
V
P
G
D
V
S
L
Q
L
S
TL
E
M
D
D
R
S
H
---
Y
T
C
E
V
T
W
Q
T
P
D
G
N
Q
-
V
V
R
-
D
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40
HHSearch
44.84
15%
-74
- C3 -
-
4Z18
-
PD1L1_HUMAN
A:
[10-102]
---------------------------
L
Y
V
V
E
Y
G
S
N
M
T
I
E
C
K
F
P
V
E
K
Q
L
D
L
A
A
L
I
V
Y
W
E
M
-
E
-------
D
K
N
I
I
Q
-
F
-
V
H
G
E
E
D
L
K
V
Q
H
S
S
Y
R
-
Q
R
A
R
L
L
K
D
Q
L
S
L
G
N
A
A
L
Q
I
T
--
D
V
K
L
Q
-
D
A
G
V
Y
R
C
M
I
S
Y
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
46
Fugue
44.83
14%
-70
- C3 -
-
1F97
-
JAM1_MOUSE
A:
[1-212]
------------------
K
G
S
V
Y
T
A
Q
S
D
V
Q
V
P
E
N
E
S
I
K
L
T
C
-----
T
Y
S
G
F
S
S
P
R
V
E
W
K
F
-
V
-------
Q
G
S
-----------
T
T
A
L
V
C
Y
N
S
Q
-
I
T
A
P
Y
-
A
D
R
V
T
F
S
S
S
G
I
T
F
S
--
S
V
T
-
R
K
D
N
G
E
Y
T
C
M
V
S
E
E
G
G
Q
N
Y
G
-
E
V
S
-
I
H
L
T
V
L
V
PPSKP
T
I
S
V
P
S
S
V
T
I
G
N
R
A
V
-----
L
T
C
S
E
H
D
G
S
P
P
S
-
E
Y
S
W
F
K
D
G
I
S
M
L
T
T
R
A
F
M
N
S
S
F
T
I
D
PKSG
D
L
I
F
D
P
V
T
A
F
D
S
G
E
Y
Y
C
Q
A
Q
N
G
Y
G
T
A
M
R
S
E
A
A
H
M
D
A
V
E
L
N
V
G
G
-----------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
44.21
31%
-32
- C3 -
-
2ICF
-
VSIG4_HUMAN
S:
[19-111]
------------------------------------
V
N
L
P
C
T
Y
D
P
L
--
Q
G
Y
T
Q
V
L
V
K
W
L
V
Q
R
-------
G
S
D
P
V
T
I
F
-
L
R
D
S
-
S
G
D
H
I
Q
Q
A
K
Y
-
Q
G
R
L
H
-
V
S
H
K
V
P
G
D
V
S
L
Q
L
S
TL
E
M
D
D
R
S
H
---
Y
T
C
E
V
T
W
Q
T
P
D
G
N
Q
-
V
V
R
-
D
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
49
Fugue
44.17
13%
-50
- C3 -
-
1BIH
-
HEMO_HYACE
A:
[5-98]
-----------------
K
Y
P
V
L
K
D
Q
P
A
E
V
L
F
R
E
N
N
P
T
V
L
E
C
I
I
E
G
----
N
D
Q
G
V
K
Y
S
W
K
K
-
D
-------
G
K
S
Y
-------
N
W
-
Q
E
H
N
A
A
L
R
K
D
-
E
G
S
L
V
-
F
L
R
P
Q
A
S
D
---------------
E
G
H
Y
Q
C
F
A
E
T
P
A
G
V
A
S
S
R
V
I
S
-
F
R
K
T
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------