@TOME V3
(Feb 2022)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
3D Alignment Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
3D Alignment Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
PDB Ligands
Affinity Score
Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
Sequence Alignment
Tab of Complexes
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : CFDP1_HUMAN: (2020-01-31 )
MEEFDSEDFSTSEEDEDYVPSGGEYSEDDVNELVKEDEVDGEEQTQKTQGKKRKAQSIPARKRRQGGLSLEEEEEEDANSESEGSSSEEEDDAAEQEKGIGSEDARKKKEDELWASFLNDVGPKSKVPPSTQVKKGEETEETSSSKLLVKAEELEKPKETEKVKITKVFDFAGEEVRVTKEVDATSKEAKSFFKQNEKEKPQANVPSALPSLPAGSGLKRSSGMSSLLGKIGAKKQKMSTLEKSKLDWESFKEEEGIGEELAIHNRGKEGYIERKAFLDRVDHRQFEIERDLRLSKMKP
Atome Classification :
(20 SA)
-----------........----.10........20........30----......------..40---------........50........60.....-...70-...-......-80........90-......----.---------.100..---..-...110.....--------..120....---...-------130.-.-....--.140-...----.....150--.......-----.160------------------.....---...170---------------.-.......180........190..-----------------...----..200.....--------.----------..210-.-......220..-..------------------------...230...--.-----...240.-...------..-.250.-----.....-.260..--.....----270----.--...---...---..280...--------....290-.......
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
-----------MEEFDSED----FSTSEEDEDYVPSGGEY
S
E
D
D
V
N
----
E
L
V
K
ED------EVD
G
---------
E
E
Q
T
Q
K
T
QGKKR
K
A
QSI
P
A
R
K
R
RQG-GLSL--E
E
E
-
E
EEDAN-SESEGSSSEEE
D
-
D
A
A
E
Q
E----K---------GIG
S
E
D
---
A
R
-
K
K
K
E
D
E
L
W
A
S
F
--------
L
N
DVGPKSK---VPP-------STQV-K-KGEE--TEE--TSS----S
K
L
L
V
K
A
---
E
E
LEKPK-----ET
E
-------------------
K
V
K
I
T
---
K
V
FD-F---------------A-GE
E
V
R
V
T
KE-VDA
T
S
K
E
A
K
S
F
F
K
-----------------QNE----KEKP-QANVP--------S----------ALPSL-P-AGSGLKRSS
G
M
-
S
S
------------------------
L
L
G
KIGA
K
K
--
Q
-----
K
M
S
T
L
E
K
-SKL------
D
W
-
E
S
F
K
E
-----EEGIG-EE
L
A
I
H--NRGKE----G------
Y
--
I
E
R
---
K
A
F
---
L
D
R
VDH
R
Q
--------
F
E
I
E
R
DL-RLSKMKP
27
Fugue
77.52
16%
154
* C7 *
-
5GAP
-
PRP3_YEAST
G:
[150-467]
-------------
L
L
D
L
S
K
----
F
K
I
Y
Y
D
N
N
H
G
Y
E
W
W
D
T
A
Y
L
D
E
K
G
----
E
L
M
E
K
Y
------
D
M
N
G
---------
T
S
P
A
E
E
K
L
A
E
D
I
D
E
V
D
D
D
D
D
D
E
H
P
S
-
I
R
Y
V
--
A
H
P
-
L
P
E
K
I
N
-
E
A
K
V
S
I
K
A
Y
L
T
Q
-
H
E
R
K
R
L
----
R
---------
R
N
R
R
K
M
---
A
R
-
E
A
R
E
I
K
I
K
L
G
L
--------
L
P
K
P
E
P
K
V
K
---
L
S
N
-------
M
M
S
V
-
F
-
E
N
D
Q
NI
T
D
P
--
T
A
W
----
E
K
V
V
K
D
Q
---
V
D
L
R
K
R
K
-----
H
L
E
-------------------
E
N
E
R
R
---
H
E
D
A
-
I
---------------
K
-
R
R
K
E
A
V
N
M
N
-
V
E
K
P
T
V
Y
H
C
K
V
F
Q
FKNL-------------
Q
N
P
----
K
I
R
F
-
K
L
K
M
N
--------
S
----------
K
E
L
S
L
-
K
--
G
L
C
L
R
I
R
D
D
G
-
P
G
------------------------
I
I
I
V
V
G
N
E
K
SC
K
-----
F
Y
E
N
L
V
M
-
K
R
I
------
K
W
N
E
D
F
E
L
-----
H
T
N
T
G
D
I
K
M
D
M
H
--
N
N
S
I
S
KTWE
G
------
Y
--
L
Q
D
CKF
K
G
W
---
F
M
K
V
C
N
D
Q
--------
D
S
L
L
R
T
L
-
G
Q
F
D
S
E
H
32
Fugue
72.33
17%
104
- C6 -
-
5CUY
1
?
A:
[18-409]
DLASAEVAGLP
V
S
A
L
H
G
T
N
----
I
S
T
G
R
G
S
E
A
D
V
A
E
P
I
Q
E
A
V
D
R
K
V
----
S
E
L
D
L
A
------
A
Y
D
K
---------
D
D
F
T
-
Q
P
M
I
K
K
I
M
S
R
L
F
S
A
F
D
V
T
H
L
-
G
-
Y
L
--
T
P
D
-
K
V
E
E
V
C
-
R
Y
L
G
R
N
M
S
D
G
D
V
-
K
A
M
K
A
E
----
I
---------
N
A
I
D
G
H
---
V
T
-
F
E
K
F
W
A
W
W
C
S
H
PVHSRTKC
F
S
M
V
S
A
D
F
S
---
M
P
Y
-------
H
Q
Q
Q
-
L
-
V
V
H
E
--
K
G
E
MY
T
P
S
----
Y
R
V
L
Y
F
F
---
R
D
L
E
T
G
R
-----
E
R
Q
VSPWHDIPLYVRDLVRTKP
E
A
T
P
M
---
N
R
Y
N
-
F
---------------
I
-
C
E
I
P
K
W
T
R
A
K
F
E
I
A
T
G
E
S
F
N
P
I
K
-----------------
Q
D
I
----
K
N
G
V
-
P
R
F
Y
K
HGDMMWNY
G
----------
A
F
P
Q
T
-
W
-
E
S
T
E
V
L
F
E
A
G
V
-
T
G
DNDPVDAVEIGMTQFKVGQVSAVK
V
L
G
V
L
G
M
I
D
--
E
GEMDW
K
V
V
C
I
S
H
-
S
D
P
ICHFLR
D
I
-
H
D
V
P
K
FLPGC
L
D
A
I
R
-
E
W
F
R
V
Y
--
K
I
C
Q
G
----
G
------
E
--
A
S
H
---
F
A
F
DGE
F
K
D
K
E
Y
A
M
--------
K
V
I
D
E
S
H
-
N
M
W
H
N
L
R
31
Fugue
64.53
19%
18
- C6 -
-
5TPI
-
?
A:
[7-211]
----------------
Q
G
L
----
F
S
L
G
S
------------------------------------------------------------
L
E
S
T
A
A
V
R
I
P
S
T
-
L
A
H
F
--
N
Q
R
-
Y
P
K
I
H
L
-
A
L
S
T
G
P
S
G
T
M
I
D
-
G
V
L
E
--------------------------------
G
A
L
S
A
A
F
--------
V
D
--
G
P
L
------------------
V
-
H
-
P
G
L
E
--
G
L
P
--
V
F
P
----
E
E
M
M
I
V
A
---
P
Y
G
H
A
P
-------------------------------
I
T
---
R
A
S
E
-
V
---------------
N
-
G
A
N
V
Y
A
F
R
A
-
N
C
S
Y
R
R
H
F
E
S
W
F
H
-----------------
A
D
R
ATPG
R
I
H
E
-
M
E
S
Y
H
--------
G
----------
M
L
A
C
V
-
I
-
A
G
A
G
L
A
L
I
P
---
R
S
------------------------
M
L
E
S
M
P
G
H
Q
--
Q
---------------
V
------
S
A
-
W
P
L
A
E
-----
E
W
R
W
L
-
T
T
W
L
V
W
--
R
R
G
A
K
----
T
---------
R
Q
L
---
E
A
F
---
I
A
L
L
N
E
D
R
--------
Q
T
V
V
S
P
---------
2
PsiBlast_PDB
54.56
19%
244
- C5 -
-
6HYP
1
MDN1_YEAST
A:
[753-2911]
-------------
E
E
D
A
G
E
----
T
E
T
A
L
D
E
E
E
----
G
A
E
E
D
V
D
M
T
N
----
D
E
G
K
E
D
------
E
E
N
G
---------
P
E
E
Q
A
M
S
D
E
E
E
L
K
Q
D
A
A
M
E
E
N
K
E
K
G
-
G
------
E
Q
-
N
T
E
G
L
D
-
G
V
E
E
K
A
D
T
E
D
I
D
Q
E
A
A
V
Q
Q
DSGS
K
---------
G
A
G
A
D
A
---
T
D
-
T
Q
E
Q
D
----------------
D
V
G
G
S
G
--------------
T
T
Q
N
-
T
-
Y
E
E
D
--
Q
E
D
--
V
T
K
----
N
N
-----------
E
E
S
R
-----
E
E
A
-------------------
T
A
A
L
K
---
Q
L
G
D
-
S
---------------
M
-
K
E
Y
H
R
R
R
Q
D
-
I
----
K
E
A
Q
T
N
G
E
-----------------
E
D
E
----
N
L
E
K
-
N
N
E
R
P
--------
D
----------
E
F
E
H
V
-
E
-
G
A
N
T
E
T
D
T
Q
A
L
-
G
S
------------------------------
A
T
Q
--
D
-----
Q
L
Q
T
I
D
------------------------------
E
D
M
A
I
D
--
D
D
R
E
E
----
Q
------
E
--
V
D
Q
---
K
E
L
---
V
E
D
A
D
D
E
K
--------
M
D
I
D
E
E
E
-
M
L
S
D
I
--
3
PsiBlast_PDB
54.28
19%
242
- C5 -
-
6I26
-
MDN1_YEAST
A:
[753-3804]
-------------
E
E
D
A
G
E
----
T
E
T
A
L
D
E
E
E
----
G
A
E
E
D
V
D
M
T
N
----
D
E
G
K
E
D
------
E
E
N
G
---------
P
E
E
Q
A
M
S
D
E
E
E
L
K
Q
D
A
A
M
E
E
N
K
E
K
G
-
G
------
E
Q
-
N
T
E
G
L
D
-
G
V
E
E
K
A
D
T
E
D
I
D
Q
E
A
A
V
Q
Q
DSGS
K
---------
G
A
G
A
D
A
---
T
D
-
T
Q
E
Q
D
----------------
D
V
G
G
S
G
--------------
T
T
Q
N
-
T
-
Y
E
E
D
--
Q
E
D
--
V
T
K
----
N
N
-----------
E
E
S
R
-----
E
E
A
-------------------
T
A
A
L
K
---
Q
L
G
D
-
S
---------------
M
-
K
E
Y
H
R
R
R
Q
D
-
I
----
K
E
A
Q
T
N
G
E
-----------------
E
D
E
----
N
L
E
K
-
N
N
E
R
P
--------
D
----------
E
F
E
H
V
-
E
-
G
A
N
T
E
T
D
T
Q
A
L
-
G
S
------------------------------
A
T
Q
--
D
-----
Q
L
Q
T
I
D
------------------------------
E
D
M
A
I
D
--
D
D
R
E
E
----
Q
------
E
--
V
D
Q
---
K
E
L
---
V
E
D
A
D
D
E
K
--------
M
D
I
D
E
E
E
-
M
L
S
D
I
--
36
Fugue
53.32
13%
-14
- C6 -
-
5FNP
1
YTFE_ECOLI
A:
[2-220]
--------------------------------------
A
Y
R
D
Q
P
L
G
----
E
L
A
L
S
--------
I
P
R
-----------------------
A
S
A
L
F
R
K
Y
D
M
D
-
Y
A
A
G
--
G
K
Q
-
T
L
A
R
A
A
-
A
R
K
E
L
D
V
E
V
I
E
A
-
E
L
A
K
L
A
----
E
---------
Q
P
I
E
K
D
---
W
R
-
S
A
P
L
A
E
I
I
D
H
I
--------
I
V
R
Y
---------------------------
H
D
--
R
H
R
--
E
Q
L
----
P
E
L
I
L
Q
A
---
T
K
V
E
R
V
H
-----
A
D
K
-------------------
P
S
V
P
K
---
G
---------------------------
L
T
K
Y
-
L
T
M
L
H
E
E
L
S
S
H
M
M
-----------------
K
E
E
----
Q
I
---------------------------
L
F
P
M
I
-
K
-
Q
G
M
G
S
Q
A
M
G
P
I
-
S
V
------------------------
M
E
S
E
H
D
E
A
G
--
E
-----
L
L
E
V
I
K
H
-
T
---------------------
T
N
N
V
T
-
P
P
P
E
A
C
--
T
T
W
K
A
----
M
------
Y
--
N
G
I
---
N
E
L
---
I
D
D
L
-
M
D
H
--------
I
S
L
E
N
N
V
-
L
F
P
R
A
L
A
28
Fugue
51.24
15%
74
- C6 -
-
5J1G
1
?
A:
[5-232]
----------------------------------------
Q
E
E
S
R
C
----
Q
R
C
I
S
E
------
L
K
D
I
---------
R
L
Q
L
E
A
C
E
T
R
T
V
H
R
L
R
L
P
L
D
K
E
P
A
R
-
E
C
A
Q
--
R
I
A
-
E
Q
Q
K
A
Q
-
A
E
V
E
G
L
G
K
G
V
A
R
-
L
S
A
E
A
E
----
K
---------
V
L
------------------------------------------------------------
A
L
--
P
E
P
--
S
P
A
----
A
P
T
L
R
S
E
---
L
E
L
T
L
G
K
-----
L
E
Q
-------------------
V
R
S
L
S
---
A
I
Y
L
--------------------
E
K
L
K
T
I
S
L
-
V
I
R
G
T
Q
G
A
E
E
V
L
R
-----------------
A
H
E
----
E
Q
L
K
-
E
A
Q
----------------------------------
A
V
P
A
T
L
-
P
E
------------------------
L
E
A
T
K
A
S
L
K
--
K
-----
L
R
A
Q
A
E
A
-
Q
Q
P
------
T
F
-
D
A
L
R
D
-----
E
L
R
G
A
-
Q
E
V
G
E
R
--
L
Q
Q
R
H
----
G
------
E
RD
V
E
V
---
E
R
W
---
R
E
R
V
A
Q
L
L
--------
E
R
W
Q
A
V
L
-
A
Q
T
D
V
R
Q
35
Fugue
50.27
16%
-
- C6 -
-
3EB8
-
VIRA_SHIFL
A:
[53-399]
-----------
A
E
K
H
S
E
K
K
LMDS
F
S
P
S
L
S
Q
D
---
K
M
D
G
E
F
A
H
A
N
I
D
GISI
R
L
C
L
N
K
GICSVF
Y
L
D
G
---------
D
K
I
Q
S
T
Q
L
S
S
K
E
Y
N
N
L
L
S
S
L
P
P
K
Q
F
-
N
L
G
K
VH
T
I
T
-
A
P
V
S
G
N
-
F
K
T
H
K
P
A
P
E
V
I
E
-
T
A
I
N
C
C
----
T
---------
S
I
I
P
N
D
---
D
Y
-
F
H
V
K
D
T
D
F
N
S
V
--------
W
H
D
I
Y
R
D
I
R
---
A
S
D
SN-----
S
T
K
I
-
Y
F
N
N
I
E
--
I
P
L
--
K
L
I
----
A
D
L
I
N
E
L
GIN
E
F
I
D
S
K
K
-----
E
L
Q
-------------------
M
L
S
Y
N
---
Q
V
N
K
-
I
---------------
I
-
N
S
N
F
P
Q
Q
D
L
-
C
F
Q
T
E
K
L
L
F
T
S
L
F
-----------------
Q
D
-----------------------
P
----------
A
F
I
S
A
-
L
-
T
S
A
F
W
Q
S
L
H
I
T
-
S
S
------------------------
S
V
E
H
I
Y
A
Q
I
--
M
-----
S
E
N
I
E
N
R
-
L
N
F
----------------------
M
P
-
E
Q
R
V
I
N
--
N
C
G
H
I
----
I
------
K
--
I
N
A
---
V
-----------
R
A
--------
Y
E
V
S
S
S
I
-
L
P
S
H
I
T
C
4
PsiBlast_PDB
49.43
19%
233
- C5 -
-
6I27
-
MDN1_YEAST
A:
[847-3803]
-------------
E
E
D
A
G
E
----
T
E
T
A
L
D
E
E
E
----
G
A
E
E
D
V
D
M
T
N
----
D
E
G
K
E
D
------
E
E
N
G
---------
P
E
E
Q
A
M
S
D
E
E
E
L
K
Q
D
A
A
M
E
E
N
K
E
K
G
-
G
------
E
Q
-
N
T
E
G
L
D
-
G
V
E
E
K
A
D
T
E
D
I
D
Q
E
A
A
V
Q
Q
DSGS
K
---------
G
A
G
A
D
A
---
T
D
-
T
Q
E
Q
D
----------------
D
V
G
G
S
G
--------------
T
T
Q
N
-
T
-
Y
E
E
D
--
Q
E
D
--
V
T
K
----
N
N
-----------
E
E
S
R
-----
E
E
A
-------------------
T
A
A
L
K
---
Q
L
G
D
-
S
---------------
M
-
K
E
Y
H
R
R
R
Q
D
-
I
----
K
E
A
Q
T
N
G
E
-----------------
E
D
E
----
N
L
E
K
-
N
N
E
R
P
--------
D
----------
E
F
E
H
V
-
E
-
G
A
N
T
E
T
D
T
Q
A
L
-
G
S
------------------------------
A
T
Q
--
D
-----
Q
L
Q
T
I
D
------------------------------
E
D
M
A
I
D
--
D
D
R
E
E
----
Q
------
E
--
V
D
Q
---
K
E
L
---
V
E
D
A
D
D
E
K
--------
M
D
I
D
E
E
E
-
M
L
S
D
I
--
40
Fugue
46.40
14%
101
- C3 -
-
4DNH
2
?
A:
[2-387]
--------------
L
V
S
I
D
----
L
P
I
E
G
R
L
A
R
Y
D
L
T
G
R
P
V
P
F
N
S
R
D
----
A
K
A
F
S
R
------
V
A
F
A
AAHVVADPL
A
D
N
D
P
W
L
A
P
A
I
D
W
E
R
T
L
A
F
R
H
R
L
W
D
L
G
L
G
V
--
A
E
S
M
D
T
A
Q
R
G
M
G
L
G
W
P
E
A
R
E
L
I
R
-
R
S
L
A
E
A
----
R
GRPDALIAC
G
A
G
T
D
H
LAP
G
P
-
D
V
S
I
D
D
I
L
A
A
Y
--------
E
S
Q
I
E
A
I
E
A
---
E
G
G
-------
R
I
I
L
M
A
-
S
R
A
L
--
A
A
A
--
A
K
G
----
P
E
D
Y
I
R
V
---
Y
D
R
V
L
S
Q
-----
V
K
E
-------------------
P
V
I
I
H
---
W
L
G
E
M
F
DPALEGYWGNADHMA
A
M
K
T
C
L
D
V
L
E
A
-
H
A
A
K
V
D
G
I
K
I
S
L
L
-----------------
S
K
E
----
K
E
I
V
M
R
R
Q
L
P
--------
K
GVRMYTGDDF
N
Y
A
E
L
-
I
-
A
G
D
E
E
G
H
S
D
A
L
L
G
I
------------------------
F
D
A
I
A
P
V
A
S
--
A
-----
A
L
E
A
L
G
S
-
G
--------
R
N
-
G
E
F
F
E
-----
L
L
E
P
T
-
V
P
L
S
R
H
IF
K
A
P
T
R
----
F
------
Y
--
K
T
G
---
V
V
F
---
L
A
Y
L
N
G
L
Q
DHFVMIGG
Q
Q
S
A
R
S
L
V
H
L
A
E
L
F
R
33
Fugue
44.74
10%
-1
- C6 -
-
2OCC
-
COX3_BOVIN
C:
[1-261]
-----------
M
T
H
Q
T
H
A
Y
----
H
M
V
N
P
S
P
W
P
L
T
G
A
L
S
A
L
L
M
T
S
G
L
----
T
M
W
F
H
F
-----------------------
N
S
M
-----
T
L
L
M
I
G
L
T
T
N
M
L
T
-
M
Y
Q
W
--
W
R
D
-
V
I
R
E
S
T
-
F
Q
G
H
H
T
P
A
V
Q
K
G
-
L
R
Y
G
M
I
----
L
---------
F
I
I
S
E
V
---
L
F
F
T
G
F
F
W
A
F
Y
H
S
S
--------
L
A
P
T
-
P
E
L
G
-------------
G
C
-
W
-
P
-
P
T
G
I
--
H
P
L
--
N
P
L
----
E
V
P
L
L
N
T
---
S
V
L
L
A
S
G
-----
V
S
I
-------------------
T
W
A
H
H
---
S
L
M
------------------
E
-
G
D
R
K
H
M
L
Q
A
-
L
F
I
T
I
T
L
G
V
Y
F
T
L
-----------------
L
Q
A
----
S
E
Y
Y
-
E
A
--
P
--------
F
----------
T
I
-
S
D
G
V
-
Y
G
S
T
F
F
V
A
T
G
F
-
H
G
------------------------
L
H
V
I
I
G
S
T
F
--
L
-----
I
V
C
F
F
R
Q
-
L
K
F
------
H
F
-
T
S
-----------------------
N
H
H
F
----
G
------
F
--
E
A
G
---
A
W
Y
---
W
H
F
V
D
V
V
W
--------
L
F
L
Y
V
S
I
-
Y
W
W
G
S
--
5
PsiBlast_PDB
44.04
22%
213
- C5 -
-
6FML
-
?
G:
[964-1619]
------------------------------------------
D
E
A
L
----
Q
E
V
R
E
Q
------
E
L
W
A
---------
E
K
E
R
K
K
D
M
Q
R
K
R
R
R
E
K
S
M
A
A
T
L
E
Q
Q
-
A
A
A
L
--
Q
K
---------------
A
S
Q
A
E
D
-
E
A
E
R
L
K
----
Y
---------
I
R
E
A
E
R
---
A
N
-
K
K
V
Q
Q
T
K
Y
I
L
Q
--------
K
G
I
K
G
P
A
R
N
---
L
P
P
IEPNLEG
G
T
M
A
-
T
-
F
S
A
E
--
N
M
E
--
P
G
K
----
V
K
G
K
G
R
G
---
G
R
L
K
K
S
K
EQKQA
E
K
E
-------------------
Q
A
E
L
A
---
Q
A
A
I
-
D
---------------
A
-
G
E
E
P
P
S
K
E
E
-
T
K
I
R
I
K
L
S
K
A
--
K
-----------------
A
S
A
----
K
E
E
A
-
E
K
D
K
E
--------
N
----------
K
E
P
K
Q
-
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------
42
Fugue
42.06
16%
62
- C2 -
-
1HDM
-
DMA_HUMAN
A:
[13-196]
----------------------------------------------------------------------------
L
Q
N
H
T
F
L
H
-
T
V
Y
C
Q
D
G
S
P
S
V
G
L
S
E
-
A
Y
D
E
--
D
Q
L
-
F
F
F
D
F
S
-
Q
N
T
R
V
P
R
L
P
E
F
A
-
D
W
A
Q
E
Q
----
G
---------
D
A
I
L
F
D
---
K
E
-
F
C
E
W
M
I
Q
Q
I
P
K
--------
L
D
G
K
I
P
V
S
R
---
G
F
P
-------
I
A
E
V
-
F
-
T
L
K
P
--
L
E
F
--
G
K
P
----
N
T
L
V
C
F
V
---
S
N
L
F
P
P
M
-----
L
T
V
-------------------
N
W
H
D
H
---
S
V
P
V
-
E
-----------------
G
F
G
P
T
F
V
S
A
-
V
D
G
L
S
F
Q
A
F
S
Y
L
N
FTPEPSDIFSCIVTHEP
D
R
Y
----
T
A
I
A
-
Y
W
V
P
R
--------
N
----------
A
L
P
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
39
Fugue
39.85
23%
-73
- C6 -
-
5TOH
-
VP35_MABVM
A:
[1-52]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
D
I
------
I
W
-
D
Q
L
I
V
-----
K
R
T
L
A
-
D
L
L
I
P
I
--
N
R
Q
I
S
---------------
D
I
---
Q
S
T
---
L
S
E
V
T
T
R
V
--------
H
E
I
E
R
Q
L
-
H
E
I
T
P
V
-
19
PsiBlast_PDB
37.90
21%
154
- C5 -
-
5H0R
-
?
F:
[380-1161]
-------------------------------------------------------------------------------------------------------
S
L
--
K
Q
K
-
Y
T
N
G
V
G
-
S
I
A
Q
S
Y
L
S
S
F
T
D
-
E
I
A
K
R
V
----
N
---------
G
I
------------
H
H
D
E
A
W
L
N
F
--------
L
T
T
S
S
P
G
R
K
---
L
T
E
-------
I
E
K
L
-
E
-
V
G
G
D
--
V
A
A
--
W
S
N
----
S
R
I
V
M
Q
A
---
V
F
A
R
E
Y
R
-----
T
P
E
-------------------
R
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
37.57
32%
-64
- C5 -
-
4U9R
1
?
A:
[21-65]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
A
----
T
E
K
L
-
R
L
D
I
P
--------
V
----------
L
L
P
G
L
-
P
-
D
S
S
D
P
C
V
E
R
L
L
-
S
E
------------------------
L
R
G
K
E
G
V
E
A
--
A
-----
H
I
K
T
------------------------------------------------------------------------------------------------------
29
Fugue
36.50
23%
20
- C7 -
-
1Z4H
-
TORI_ECOLI
A:
[1-66]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
-----
Q
H
E
L
Q
P
D
-
S
L
V
------
D
L
-
K
F
I
M
A
-----
D
T
G
F
G
-
K
T
F
-
I
Y
--
D
R
I
K
S
----
G
DLPKAK
V
--
I
H
G
---
R
A
R
---
W
L
Y
R
D
H
C
E
--------
F
K
N
K
L
L
S
-
R
A
N
G
---
30
Fugue
35.99
11%
74
- C6 -
-
1PJC
1
?
A:
[1-361]
-----------------------------------------------------------------------------------------------------------------------
M
E
I
G
V
P
K
E
I
K
N
-
Q
--
E
F
R
----
V
---------
G
L
S
P
S
S
---
V
R
-
T
L
V
E
A
G
H
T
V
F
I
--------
E
T
Q
A
G
I
G
A
G
---
F
A
D
-------
Q
D
Y
V
-
Q
-
A
G
A
Q
--
V
V
P
--
S
A
K
DAWS
R
E
M
V
V
K
------
V
K
E
P
L
-----
P
A
E
-------------------
Y
D
L
M
Q
KDQ
L
L
F
T
-
Y
---------------
L
-
H
-------------
L
A
A
A
R
E
L
T
E
-----------------
Q
L
M
----
R
V
G
L
-
T
A
I
A
Y
--------
E
----------
T
V
E
L
P
-
N
R
S
L
P
L
L
T
P
M
S
I
I
-
V
P
------------------------
W
T
A
T
Q
A
L
N
N
--
S
-----
T
L
P
Y
V
V
K
L
A
N
Q
------
G
L
-
K
A
L
E
T
-----
D
D
A
L
A
-
K
G
L
N
V
Q
--
A
V
G
T
E
----
H
------
R
--
L
V
H
---
P
A
V
---
Q
Q
V
F
P
D
L
A
-----------------------
6
PsiBlast_PDB
34.44
22%
188
* C8 *
-
6HRE
-
TAU_HUMAN
A:
[304-380]
-----------------------------------------------------------------------------------------------
R
K
D
Q
G
-
G
Y
T
M
--
H
Q
D
-
Q
E
G
D
T
D
-
A
G
L
K
E
S
P
L
Q
T
P
--
E
D
G
S
E
E
----
P
---------
G
S
E
T
S
D
---
A
K
-----------------------
E
G
A
P
G
K
QAA
A
Q
P
-------
H
T
E
I
-
P
-
E
G
-------------------------------------------------------------------------------------------------------
G
K
T
K
I
A
T
P
R
G
A
-----------------
A
P
P
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
33.90
22%
192
- C8 -
-
6NWQ
-
?
A:
[305-379]
------------------------------------------------------------------------------------------------
K
D
Q
G
-
G
Y
T
M
--
H
Q
D
-
Q
E
G
D
T
D
-
A
G
L
K
E
S
P
L
Q
T
P
--
E
D
G
S
E
E
----
P
---------
G
S
E
T
S
D
---
A
K
-----------------------
E
G
A
P
G
K
QAA
A
Q
P
-------
H
T
E
I
-
P
-
E
G
-------------------------------------------------------------------------------------------------------
G
K
T
K
I
A
T
P
R
G
A
-----------------
A
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------