@TOME V3
(Feb 2022)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
3D Alignment Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
3D Alignment Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
PDB Ligands
Affinity Score
Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
Sequence Alignment
Tab of Complexes
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : CYBP_HUMAN: (2020-01-31 )
MASEELQKDLEEVKVLLEKATRKRVRDALTAEKSKIETEIKNKMQQKSQKKAELLDNEKPAAVVAPITTGYTVKISNYGWDQSDKFVKIYITLTGVHQVPTENVQVHFTERSFDLLVKNLNGKSYSMIVNNLLKPISVEGSSKKVKTDTVLILCRKKVENTRWDYLTQVEKECKEKEKPSYDTETDPSEGLMNVLKKIYEDGDDDMKRTINKAWVESREKQAKGDTEF
Atome Classification :
(20 SA)
--------------------------------------------------------.........10......----...20........30........40........50........----------------60-...--.....70......--..80.-.......90.....-----...100.....----..110...--------.....120.------------.......130.......140---.....-.-.150.....--.-.160.....--------..170.......180.......190..--------.....200..---.....210.......220......
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
--------------------------------------------------------M
A
S
E
E
L
Q
K
D
L
-
E
E
V
K
V
L
----
L
E
K
A
T
R
K
R
V
R
D
A
L
T
A
E
K
S
K
I
E
T
E
I
K
N
K
M
Q
Q
K
S
Q
K
K
A
E
L
LDNEK----------------P
A
-
A
V
V
--
A
P
ITT
G
Y
T
V
K
I
SN--YGWDQ-SD
K
F
V
K
I
Y
I
T
L
TGV-----HQVPTE
N
V
Q
V
H
----
F
TER-
S
F
D
--------
L
L
V
K
NL-NG------------
K
S
Y
S
M
I
V
N
NLLK
P
I
SVEGSS---K
K
V
KT-
D
-
T
V
L
I
L
C
R
K
K
--V-ENT
R
W
D
Y
L
T
--------
Q
V
E
K
E
C
K
EKEKPSYDTETD
P
S
E
G
L
M
N
V
--------
L
K
K
I
YEDG
D
D
---
D
M
K
R
T
I
N
K
A
W
V
E
S
R
E
K
QAKGDTEF
1
PsiBlast_PDB
90.72
96%
-126
- C6 -
-
1X5M
-
CYBP_HUMAN
A:
[6-125]
-----------------------------------------------------------------------------------------------------------------------------------------
S
-
G
V
V
--
A
P
I
T
T
G
Y
T
V
K
I
S
N
--
Y
G
W
D
Q
-
S
D
K
F
V
K
I
Y
I
T
L
T
G
V
-----
H
Q
V
P
T
E
N
V
Q
V
H
----
F
T
E
R
-
S
F
D
--------
L
L
V
K
N
L
-
N
G
------------
K
S
Y
S
M
I
V
N
N
L
L
K
P
I
S
V
E
G
S
S
---
K
K
V
K
T
-
D
-
T
V
L
I
L
C
R
K
K
--
V
-
E
N
T
R
W
D
Y
L
T
--------
Q
V
E
K
E
C
K
E
K
S
G
P
S
-----------------------------------------------------------
15
HHSearch
84.53
100%
-133
- C6 -
-
1X5M
-
CYBP_HUMAN
A:
[14-118]
----------------------------------------------------------------------------------------------------------------------------------------------------
T
G
Y
T
V
K
I
S
N
--
Y
G
W
D
Q
-
S
D
K
F
V
K
I
Y
I
T
L
T
G
V
-----
H
Q
V
P
T
E
N
V
Q
V
H
----
F
T
E
R
-
S
F
D
--------
L
L
V
K
N
L
-
N
G
------------
K
S
Y
S
M
I
V
N
N
L
L
K
P
I
S
V
E
G
S
S
---
K
K
V
K
T
-
D
-
T
V
L
I
L
C
R
K
K
--
V
-
E
N
T
R
W
D
Y
L
T
--------
Q
V
E
K
E
C
------------------------------------------------------------------
47
Fugue
59.52
22%
63
- C2 -
-
4TXD
-
?
A:
[21-369]
KRDVLAELGLGDLRPYLRSIGDKDRIFPKAHRIEVVFLVRAANYLLLRTEGAGTIN
M
T
T
L
E
Y
S
G
G
A
-
M
E
V
P
V
I
QPQK
L
M
A
V
T
R
R
Q
M
L
Q
L
L
R
E
Y
R
D
S
L
D
E
V
S
K
R
W
L
V
Q
E
V
I
G
K
A
K
D
L
G
F
K
K
VSEEWNCTIQGMDGFC
P
H
-
C
T
I
FG
A
A
L
T
E
Q
H
N
E
K
F
G
G
LS
I
G
I
K
T
-
R
V
R
F
D
P
A
F
A
T
Q
R
R
I
TPETH
N
K
V
T
E
G
H
L
S
M
T
GQAL
F
S
E
V
-
H
V
E
PGTVFIGR
A
E
L
V
D
L
-
T
E
------------
P
E
L
V
A
T
L
Y
S
L
A
T
L
R
E
L
G
G
R
S
GIY
G
T
V
R
V
-
E
-
I
L
G
V
K
A
G
K
Y
--
A
-
S
T
T
A
Y
D
L
A
A
ENAGKGYE
E
V
K
K
N
L
K
E
R
L
E
K
L
G
F
T
P
V
D
N
S
K
L
L
A
A
V
DHKDPNGL
F
K
D
L
W
R
S
S
I
D
---
F
A
E
K
M
V
--
K
W
V
E
E
L
----
K
G
G
G
--
36
Fugue
59.03
31%
-121
- C6 -
-
1RL1
-
SGT1_HUMAN
A:
[138-229]
---------------------------------------------------------------------------------------------------------------------------------------------------------
S
K
I
K
--
Y
D
W
Y
Q
-
T
E
S
Q
V
V
I
T
L
M
I
K
N
V
--------
Q
K
N
D
V
N
V
E
----
F
S
E
K
-
E
L
S
--------
A
L
V
K
L
P
-
S
G
------------
E
D
Y
N
L
K
L
E
-
L
L
H
P
I
I
P
E
Q
S
T
---
F
K
V
L
S
-
T
-
K
I
E
I
K
L
K
K
P
----
E
A
V
R
W
E
K
L
E
--------
G
Q
G
---------------------------------------------------------------------
5
PsiBlast_PDB
57.04
33%
-146
- C6 -
-
1RL1
-
SGT1_HUMAN
A:
[142-225]
---------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
D
W
Y
Q
-
T
E
S
Q
V
V
I
T
L
M
I
K
N
V
-----
Q
K
---
N
D
V
N
V
E
----
F
S
E
K
-
E
L
S
--------
A
L
V
K
L
P
-
S
G
------------
E
D
Y
N
L
K
L
-
E
L
L
H
P
I
I
P
E
Q
S
T
---
F
K
V
L
S
-
T
-
K
I
E
I
K
L
-
K
K
--
P
-
E
A
V
R
W
E
K
L
---------------------------------------------------------------------------------
28
HHSearch
56.97
29%
-121
- C6 -
-
1RL1
-
SGT1_HUMAN
A:
[138-229]
---------------------------------------------------------------------------------------------------------------------------------------------------------
S
K
I
K
--
Y
D
W
Y
Q
-
T
E
S
Q
V
V
I
T
L
M
I
K
N
V
-----
Q
---
K
N
D
V
N
V
E
----
F
S
E
K
-
E
L
S
--------
A
L
V
K
L
P
-
S
G
------------
E
D
Y
N
L
K
L
E
-
L
L
H
P
I
I
P
E
Q
S
T
---
F
K
V
L
S
-
T
-
K
I
E
I
K
L
K
K
P
--
E
--
A
V
R
W
E
K
L
E
--------
G
Q
G
---------------------------------------------------------------------
29
HHSearch
53.48
19%
-93
- C6 -
-
1WFI
-
A:
[6-102]
---------------------------------------------------------------------------------------------------------------------------------------------------------
S
G
P
N
--
Y
R
W
T
Q
-
T
L
A
E
L
D
L
A
V
P
F
R
V
S
-----
F
R
L
K
G
K
D
V
V
V
D
----
I
Q
R
R
-
H
L
R
--------
V
G
L
K
G
----------------
Q
P
P
V
V
D
G
E
-
L
Y
N
E
V
K
V
E
E
S
S
---
W
L
I
E
D
-
G
K
V
V
T
V
H
L
E
K
I
--
N
-
K
M
E
W
W
N
R
L
V
--------
T
S
D
P
E
I
------------------------------------------------------------------
21
HHSearch
53.23
17%
-175
- C6 -
-
2XCM
-
D:
[3-91]
-----------------------------------------------------------------------------------------------------------------------------------------------------------
Y
R
--
H
E
Y
Y
Q
-
K
P
E
E
V
V
V
T
V
F
A
K
G
I
-----
P
---
K
Q
N
V
N
I
D
----
F
G
E
Q
-
I
L
S
--------
V
V
I
E
V
P
-
G
E
------------
D
A
Y
Y
L
Q
P
R
-
L
F
G
K
I
I
P
D
K
C
K
---
Y
E
V
L
S
-
T
-
K
I
E
I
C
L
A
K
A
--
D
--
I
I
T
W
A
S
L
E
--------
H
G
----------------------------------------------------------------------
37
Fugue
52.73
15%
-77
* C6 *
-
1EJF
-
TEBP_HUMAN
A:
[1-110]
--------------------------------------------------------------------------------------------------------------------------------------------------------
M
Q
P
A
S
--
A
K
W
Y
D
-
R
R
D
Y
V
F
I
E
F
C
V
E
D
S
-----
K
-----
D
V
N
V
N
----
F
E
K
S
-
K
L
T
--------
F
S
C
L
G
G
-
S
D
------------
N
F
K
H
L
N
E
I
D
L
F
H
C
I
D
P
N
D
S
K
---
H
K
R
T
D
-
R
-
S
I
L
C
C
L
R
K
G
--
E
-
S
G
Q
S
W
P
R
L
T
--------
K
E
R
A
K
-
L
N
W
L
S
V
D
F
N
N
W
K
D
W
E
---------------------------------------------------
17
HHSearch
51.80
17%
-167
- C6 -
-
2JKI
-
SGT1A_ARATH
S:
[2-89]
-----------------------------------------------------------------------------------------------------------------------------------------------------------
Y
R
--
H
E
Y
Y
Q
-
K
P
E
E
V
V
V
T
V
F
A
K
G
I
-----
P
---
K
Q
N
V
N
I
D
----
F
G
E
Q
-
I
L
S
--------
V
V
I
E
V
P
-
G
E
------------
D
A
Y
Y
L
Q
P
R
-
L
F
G
K
I
I
P
D
K
C
K
---
Y
E
V
L
S
-
T
-
K
I
E
I
C
L
A
K
A
--
D
--
I
I
T
W
A
S
L
E
--------
H
-----------------------------------------------------------------------
34
Fugue
51.41
18%
-75
- C6 -
-
2CR0
-
A:
[1-121]
-----------------------------------------------------------------------------------------------------------------------
G
----------------
S
S
-
G
S
S
--
G
K
P
N
L
G
N
G
A
D
L
P
N
--
Y
R
W
T
Q
-
T
L
A
E
L
D
L
A
V
P
F
R
V
S
-----
F
R
L
K
G
K
D
V
V
V
D
----
I
Q
R
R
-
H
L
R
--------
V
G
L
K
G
-----------------
Q
P
P
V
V
D
G
E
L
Y
N
E
V
K
V
E
E
S
S
---
W
L
I
E
D
G
K
-
V
V
T
V
H
L
E
K
I
--
N
-
K
M
E
W
W
N
R
L
V
--------
T
S
D
P
E
I
N
T
K
S
G
P
S
S
G
---------------------------------------------------------
31
HHSearch
50.59
17%
-55
- C6 -
-
1EJF
-
TEBP_HUMAN
B:
[3-96]
----------------------------------------------------------------------------------------------------------------------------------------------------------
P
A
S
--
A
K
W
Y
D
-
R
R
D
Y
V
F
I
E
F
C
V
E
D
S
----------
K
D
V
N
V
N
----
F
E
K
S
-
K
L
T
--------
F
S
C
L
G
G
S
D
N
------------
F
K
H
L
N
E
I
D
-
L
F
H
C
I
D
P
N
D
S
K
---
H
K
R
T
D
-
R
-
S
I
L
C
C
L
R
K
G
--
E
-
S
G
Q
S
W
P
R
L
T
--------
K
E
R
A
K
L
------------------------------------------------------------------
40
Fugue
49.99
19%
-39
- C3 -
-
5M1M
-
MAT_INCAA
A:
[2-155]
---------------------------------------------------------
A
H
E
I
L
I
A
E
T
-
E
A
F
L
K
N
----
V
A
P
E
T
R
T
A
I
I
S
A
I
T
G
G
------------
K
S
A
C
K
S
A
A
K
L
I
K
N
E
H
----------------
L
P
-
L
-----------------------
M
-
S
G
E
A
T
T
M
H
I
V
M
R
C
L
-----
Y
P
--------------
E
I
K
-
P
W
K
--------
K
A
S
D
M
L
-
N
K
------------
A
T
S
S
------
L
K
K
S
E
G
R
D
I
R
---
K
Q
M
K
A
-
A
-
G
D
F
L
G
V
E
S
M
--
M
-
K
M
R
A
F
R
-------------------------------
D
D
Q
I
M
E
M
--------
V
E
E
V
Y
D
H
P
D
D
YTP
D
I
R
I
G
T
I
T
A
W
L
R
C
K
N
K
K
S
------
25
HHSearch
49.49
19%
-109
- C6 -
-
3QOR
-
NUDC_HUMAN
A:
[14-111]
--------------------------------------------------------------------------------------------------------------------------------------------------------
A
D
L
P
N
--
Y
R
W
T
Q
-
T
L
S
E
L
D
L
A
V
P
F
C
V
N
-----
F
R
L
K
G
K
D
M
V
V
D
----
I
Q
R
R
-
H
L
R
--------
V
G
L
K
----
G
------------
Q
P
A
I
I
D
G
E
-
L
Y
N
E
V
K
V
E
E
S
S
---
W
L
I
A
D
-
G
A
V
V
T
V
H
L
E
K
I
--
N
-
K
M
E
W
W
S
R
L
V
--------
S
S
D
P
E
I
------------------------------------------------------------------
46
Fugue
49.47
13%
45
- C4 -
-
5TGQ
1
?
A:
[1-226]
--------------------------------------------------------
M
N
F
K
K
Y
E
E
N
L
V
A
S
I
E
E
V
----
I
Q
R
I
I
D
D
K
H
R
-
P
N
I
I
G
K
T
R
V
G
A
E
V
S
D
Y
L
E
D
E
F
V
K
Y
I
S
S
G
K
S
S
S
----------------
L
Y
D
A
Q
G
--
A
P
K
E
K
T
K
N
P
W
D
A
R
--
C
K
F
K
F
-
M
D
R
E
E
E
I
W
I
D
F
K
A
F
-----
K
I
T
N
M
D
S
N
P
D
I
----
G
T
P
N
-
K
I
V
--------
K
F
I
H
E
---
G
------------
N
F
Y
L
V
F
V
L
V
Y
Y
E
S
K
Q
D
G
V
E
F
---
V
K
Y
N
N
-
D
-
Y
K
K
V
Y
L
L
K
D
--
V
N
E
S
F
R
I
N
P
K
P
--------
Q
M
Q
--
V
N
I
A
A
E
P
T
Y
R
T
R
E
E
F
I
H
F
F
V
K
K
--------
W
K
E
S
F
E
R
Q
I
K
---
S
L
E
K
K
E
I
M
L
K
D
L
E
D
K
L
K
N
S
N
D
N
S
I
14
HHSearch
49.36
16%
-150
- C6 -
-
2O30
1
?
A:
[5-89]
-----------------------------------------------------------------------------------------------------------------------------------------------------------
A
K
--
Y
T
W
D
Q
-
E
L
N
E
I
N
I
Q
F
P
V
T
----------
D
S
S
A
I
K
I
R
----
M
V
G
K
-
K
I
C
--------
V
K
N
Q
G
-----------------
E
I
V
I
D
G
E
-
L
L
H
E
V
D
V
S
S
L
W
---
W
V
I
N
G
-
D
-
V
V
D
V
N
V
T
K
K
--
R
--
N
E
W
W
D
S
L
L
--------
V
-----------------------------------------------------------------------
16
HHSearch
48.66
18%
-2
- C6 -
-
1WH0
-
A:
[15-124]
------------------------------------------------------------------------------------------------------------------------------------------------------
V
N
L
A
F
V
K
--
N
D
S
Y
E
K
G
P
D
S
V
V
V
H
V
Y
V
K
E
I
-----
C
---
R
D
T
S
R
V
L
----
F
R
E
Q
-
D
F
T
--------
L
I
F
Q
T
R
-
D
G
NFLRLHPGCGPH
T
T
F
R
W
Q
V
K
-
L
R
N
L
I
E
P
E
Q
C
T
---
F
C
F
T
A
-
S
-
R
I
D
I
C
L
R
K
R
--
Q
--
S
Q
R
W
G
G
L
E
--------
A
P
A
A
R
-------------------------------------------------------------------
22
HHSearch
47.66
20%
-72
- C6 -
-
1WGV
-
A:
[15-115]
------------------------------------------------------------------------------------------------------------------------------------------------------
N
G
A
V
R
E
N
--
Y
T
W
S
Q
-
D
Y
T
D
L
E
V
R
V
P
V
P
K
H
-----
V
-
V
K
G
K
Q
V
S
V
A
----
L
S
S
S
-
S
I
R
--------
V
A
M
L
E
E
-
N
G
------------
E
R
V
L
M
E
G
K
-
L
T
H
K
I
N
T
E
S
S
L
---
W
S
L
E
P
-
G
K
C
V
L
V
N
L
S
K
V
--
G
--
E
Y
W
W
N
A
I
L
--------
E
G
E
E
P
I
------------------------------------------------------------------
19
HHSearch
45.87
16%
-143
- C6 -
-
2RH0
1
NUDC2_MOUSE
B:
[9-106]
------------------------------------------------------------------------------------------------------------------------------------------------------
V
P
C
G
T
P
W
--
G
Q
W
Y
Q
-
T
L
E
E
V
F
I
E
V
Q
V
P
P
G
-------
T
R
A
Q
D
I
Q
C
G
----
L
Q
S
R
-
H
V
A
--------
L
A
V
G
G
-----------------
R
E
I
L
K
G
K
-
L
F
D
S
T
I
A
D
E
G
T
---
W
T
L
E
D
-
R
K
M
V
R
I
V
L
T
K
T
KR
D
-
A
A
N
C
W
T
S
L
L
--------
E
S
E
Y
A
-------------------------------------------------------------------
48
Fugue
44.73
19%
43
- C5 -
-
3PDD
-
?
A:
[1-190]
----------------------------------------------------------------------
M
V
T
----
I
D
S
P
V
A
G
E
R
F
E
A
--
G
K
D
I
N
I
S
A
T
V
K
S
K
---
T
P
V
S
K
V
E
F
Y
N
G
D
T
----------------
L
I
-
S
S
D
--
T
--
T
A
P
Y
T
A
K
I
T
G
--
A
A
V
G
A
-
Y
N
L
K
A
V
A
V
L
S
D
G
R
R
-----
I
E
S
P
V
T
P
V
L
V
K
----
V
I
V
K
P
T
V
K
--------
L
T
A
P
K
S
-
N
V
------------
V
A
Y
G
----
N
E
F
L
K
I
T
A
T
A
S
D
---
S
D
G
K
------------------
I
S
R
V
D
F
L
V
--------
D
G
E
V
I
G
S
D
R
E
A
P
-
Y
E
Y
E
W
K
A
V
E
G
N
H
E
I
--------
S
V
I
A
Y
D
D
D
D
A
---
A
S
T
P
D
S
V
K
I
F
V
K
Q
A
R
L
E
H
H
H
H
H
H
-