@TOME V3
(Feb 2022)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
3D Alignment Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
3D Alignment Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
PDB Ligands
Affinity Score
Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
Sequence Alignment
Tab of Complexes
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : ECHD1_HUMAN: (2020-02-01 )
MALKQEMAKSLLKTASLSGRTKLLHQTGLSLYSTSHGFYEEEVKKTLQQFPGGSIDLQKEDNGIGILTLNNPSRMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSLGTPEDGMAVCMFMQNTLTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGALKLDSKNALNIGMVEEVLQSSDETKSLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNERDLLGTVWGGPANLEAIAKKGKFNK
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70.-.......80........90........100.....-.-.-110.......120....--.----------.----.130.......140.......150.......160.......170...-....180....--...190.......200...-....210.......220.......230......-.240......--.250.......260......------.270.......280.......290.......300.....
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MA
L
K
Q
E
M
A
K
S
L
L
K
T
ASLSG
R
T
K
L
L
H
QTGL
S
L
YSTSHG
F
Y
E
E
E
V
K
K
T
L
Q
QFPGGS
I
D
L
Q
KEDN
G
I
G
I
L
TLNNP-SR
M
N
A
F
S
G
V
M
M
L
Q
L
L
E
K
V
I
E
LENWTEGK
G
L
I
V
RGA-K-N-TFSSGS
D
L
N
A
V
K
SLGTP--E----------
D
----
G
M
A
V
C
M
F
M
Q
N
T
L
T
R
F
M
RL
P
L
I
S
V
A
L
V
Q
GWALGGGA
E
F
T
T
A
C
D
F
R
LMT-
P
E
S
K
I
R
F
V
H
K
E--MGIIPSWG
G
T
T
R
L
V
E
I
IG
S
-
R
Q
A
L
K
V
L
S
G
A
LKLDSKNAL
N
I
G
M
V
E
E
V
L
QSSDE-TK
S
L
E
E
A
Q
E
W
--
L
K
Q
F
IQG
P
P
E
V
I
R
A
L
K
K
S
VC------SG
R
E
L
Y
L
E
E
A
L
QN
E
R
D
L
L
G
TVWGGP
A
N
L
E
A
I
A
KKGKFNK
53
HHSearch
87.79
26%
-18
- C4 -
-
2ZQQ
-
AUHM_HUMAN
D:
[85-333]
-----------------------------------------------------------
E
N
R
G
I
V
V
L
G
I
N
R
A
-
Y
G
K
N
S
L
S
K
N
L
I
K
M
L
S
K
A
V
D
A
L
K
S
D
K
K
V
R
T
I
I
I
R
S
E
-
V
P
G
-
I
F
C
A
G
A
D
L
K
E
R
A
K
M
S
S
S
-------------
E
----
V
G
P
F
V
S
K
I
R
A
V
I
N
D
I
A
N
L
P
V
P
T
I
A
A
I
D
G
L
A
L
G
G
G
L
E
L
A
L
A
C
D
I
R
V
A
A
-
S
S
A
K
M
G
L
V
E
T
K
--
L
A
I
I
P
G
G
G
G
T
Q
R
L
P
R
A
I
G
M
-
S
L
A
K
E
L
I
F
S
A
R
V
L
D
G
K
E
A
K
A
V
G
L
I
S
H
V
L
E
Q
N
Q
E
G
D
A
A
Y
R
K
A
L
D
L
--
A
R
E
F
L
P
Q
G
P
V
A
M
R
V
A
K
L
A
I
N
------
Q
G
M
E
V
D
L
V
T
G
L
A
I
E
E
A
C
Y
A
Q
T
I
P
T
K
D
R
L
E
G
L
L
A
F
K
E
K
R
P
54
HHSearch
87.53
24%
-27
- C4 -
-
3GKB
2
?
B:
[15-261]
-----------------------------------------------------------
S
E
H
G
V
A
R
I
I
L
D
N
P
-
P
-
V
N
V
I
G
A
T
M
M
R
E
L
R
T
V
L
T
T
L
A
D
D
S
S
V
R
V
I
V
F
S
S
A
-
D
P
E
-
F
F
L
A
H
V
D
M
R
I
G
E
K
M
D
A
L
--
Q
ELAA------
S
----
A
P
A
D
V
N
V
F
Q
A
V
G
E
L
I
R
H
Q
P
Q
V
T
I
V
K
L
A
G
K
A
R
G
G
G
A
E
F
V
A
A
A
D
M
A
F
A
A
A
E
T
A
G
L
G
Q
I
E
A
L
--
M
G
I
I
P
G
G
G
G
T
Q
Y
L
R
G
R
V
G
R
-
N
R
A
L
E
V
V
L
T
A
D
L
F
D
A
E
T
A
A
S
Y
G
W
I
N
R
A
L
P
A
D
E
----
L
D
E
Y
V
D
R
V
--
A
R
N
I
A
A
L
P
D
G
V
I
E
A
A
K
R
S
L
P
------
A
D
---
D
L
K
E
G
L
L
G
E
N
D
A
W
A
A
T
F
S
L
P
A
A
Q
Q
L
I
S
G
G
L
K
D
G
A
7
PsiBlast_PDB
87.46
27%
-91
- C4 -
-
3Q0G
1
ECHA8_MYCTU
A:
[7-235]
--------------------------------------------------------
L
V
E
R
D
Q
R
V
G
I
I
T
L
N
R
P
-
Q
A
L
N
A
L
N
S
Q
V
M
N
E
V
T
S
A
A
T
E
L
D
D
D
P
D
I
G
A
I
I
I
T
G
S
-
A
-
K
-
A
F
A
A
G
A
D
I
K
E
---
L
-
T
F
--
A
----------
D
----
A
F
T
A
D
F
F
A
T
W
G
K
L
A
A
V
R
T
P
--
T
I
A
A
V
A
G
Y
A
L
G
G
G
C
E
L
A
M
M
C
D
V
L
I
A
A
-
D
T
A
K
F
G
Q
P
E
I
K
--
L
G
V
L
P
G
M
G
G
S
Q
R
L
T
R
A
I
G
K
-
A
K
A
M
D
L
I
L
T
G
R
T
M
D
A
A
E
A
E
R
S
G
L
V
S
R
V
V
P
A
D
D
----
L
L
T
E
A
R
A
T
--
A
T
T
I
S
Q
M
S
A
S
A
A
R
M
A
K
E
A
V
N
------
R
A
F
E
S
S
L
S
E
G
L
L
Y
E
R
R
L
F
H
S
A
F
A
----------------
14
PsiBlast_PDB
87.26
24%
-98
- C4 -
-
3PEA
1
?
A:
[8-248]
------------------------------------------------------
L
S
V
R
V
E
D
H
-
I
A
V
A
T
L
N
H
--
A
P
A
N
A
M
S
S
Q
V
M
H
D
V
T
E
L
I
D
Q
V
E
K
D
D
N
I
R
V
V
V
I
H
G
E
-
G
-
R
-
F
F
S
A
G
A
D
I
K
E
F
T
S
V
T
E
A
--
K
----------
Q
----
A
T
E
L
A
Q
L
G
Q
V
T
F
E
R
V
E
K
C
S
K
P
V
I
A
A
I
H
G
A
A
L
G
G
G
L
E
F
A
M
S
C
H
M
R
F
A
T
-
E
S
A
K
L
G
L
P
E
L
T
--
L
G
L
I
P
G
F
A
G
T
Q
R
L
P
R
Y
V
G
K
-
A
K
A
C
E
M
M
L
T
S
T
P
I
T
G
A
E
A
L
K
W
G
L
V
N
G
V
F
A
---
E
-
E
T
F
L
D
D
T
L
K
V
--
A
K
Q
I
A
G
K
S
P
A
T
A
R
A
V
L
E
L
L
Q
------
T
T
K
S
S
H
Y
Y
E
G
V
Q
R
E
A
Q
I
F
G
E
V
F
T
S
E
D
G
R
E
G
V
A
-------
4
PsiBlast_PDB
86.98
27%
-90
- C4 -
-
3H81
3
ECHA8_MYCTU
A:
[28-256]
--------------------------------------------------------
L
V
E
R
D
Q
R
V
G
I
I
T
L
N
R
P
-
Q
A
L
N
A
L
N
S
Q
V
M
N
E
V
T
S
A
A
T
E
L
D
D
D
P
D
I
G
A
I
I
I
T
G
S
-
A
-
K
-
A
F
A
A
G
A
D
I
K
E
M
A
D
L
-
T
F
--
A
----------
D
----
A
F
T
A
D
F
F
A
T
W
G
K
L
A
A
V
R
T
P
--
T
I
A
A
V
A
G
Y
A
L
G
G
G
C
E
L
A
M
M
C
D
V
L
I
A
A
-
D
T
A
K
F
G
Q
P
E
I
K
--
L
G
V
L
P
G
M
G
G
S
Q
R
L
T
R
A
I
G
K
-
A
K
A
M
D
L
I
L
T
G
R
T
M
D
A
A
E
A
E
R
S
G
L
V
S
R
V
V
P
A
D
D
----
L
L
T
E
A
R
A
T
--
A
T
T
I
S
Q
M
S
A
S
A
A
R
M
A
K
E
A
V
N
------
R
A
F
E
S
S
L
S
E
G
L
L
Y
E
R
R
L
F
H
S
A
F
A
----------------
25
Fugue
86.64
23%
-15
- C4 -
-
1WDK
3
FADB_PSEFR
A:
[1-715]
M
I
Y
E
G
K
-----------------------------------------------
A
I
T
V
T
A
L
E
S
G
I
V
E
L
K
F
D
L
K
G
E
S
V
N
K
F
N
R
L
T
L
N
E
L
R
Q
A
V
D
A
I
K
A
D
A
S
V
K
G
V
I
V
S
S
G
-
K
-
D
-
V
F
I
V
G
A
D
I
T
E
F
V
E
N
F
K
L
PD
A
----------
E
----
L
I
A
G
N
L
E
A
N
K
I
F
S
D
F
E
D
L
N
V
P
T
V
A
A
I
N
G
I
A
L
G
G
G
L
E
M
C
L
A
A
D
F
R
V
M
A
-
D
S
A
K
I
G
L
P
E
V
K
--
L
G
I
Y
P
G
F
G
G
T
V
R
L
P
R
L
I
G
V
-
D
N
A
V
E
W
I
A
S
G
K
E
N
R
A
E
D
A
L
K
V
S
A
V
D
A
V
V
---
T
A
-
D
K
L
G
A
A
A
L
D
L
--
I
K
R
A
I
S
G
E
L
D
Y
K
A
K
R
Q
P
K
L
E
KLKLNA
I
E
Q
M
M
A
F
E
T
A
K
G
F
V
A
G
Q
A
G
P
N
Y
P
A
P
V
E
A
I
K
T
I
Q
K
A
A
N
F
G
52
HHSearch
86.46
24%
-94
- C4 -
-
2QQ3
2
?
L:
[11-252]
-----------------------------------------------------------
Q
E
G
A
V
G
I
I
E
L
A
R
P
-
D
V
L
N
A
L
S
R
Q
M
V
A
E
I
V
A
A
V
E
A
F
D
R
N
E
K
V
R
V
I
V
L
T
G
R
-
G
-
R
-
A
F
A
A
G
A
D
I
Q
E
M
A
K
D
D
P
I
------------------
R
L
E
W
-
L
N
Q
F
A
D
W
D
R
L
S
I
V
K
T
P
M
I
A
A
V
N
G
L
A
L
G
G
G
F
E
L
A
L
S
C
D
L
I
V
A
S
-
S
A
A
E
F
G
F
P
E
V
N
--
L
G
V
M
P
G
A
G
G
T
Q
R
L
T
K
L
I
G
P
-
K
R
A
L
E
W
L
W
T
G
A
R
M
S
A
K
E
A
E
Q
L
G
I
V
N
R
V
V
S
P
E
L
----
L
M
E
E
T
M
R
L
--
A
G
R
L
A
E
Q
P
P
L
A
L
R
L
I
K
E
A
V
Q
------
K
A
V
D
Y
P
L
Y
E
G
M
Q
F
E
R
K
N
F
Y
L
L
F
A
S
E
D
Q
K
E
G
M
A
A
F
L
E
K
R
K
46
HHSearch
86.43
21%
-46
- C4 -
-
1DCI
4
ECH1_RAT
B:
[5-266]
------------------------------------------------------
I
Q
V
T
S
A
Q
K
H
V
L
H
V
Q
L
N
R
P
-
E
K
R
N
A
M
N
R
A
F
W
R
E
L
V
E
C
F
Q
K
I
S
K
D
S
D
C
R
A
V
V
V
S
G
A
-
G
-
K
-
M
F
T
S
G
I
D
L
M
D
M
A
S
D
I
L
Q
--
P
PGDDVARIAW
Y
----
L
R
D
L
I
S
R
Y
Q
K
T
F
T
V
I
E
K
C
P
K
P
V
I
A
A
I
H
G
G
C
I
G
G
G
V
D
L
I
S
A
C
D
I
R
Y
C
T
-
Q
D
A
F
F
Q
V
K
E
V
D
--
V
G
L
A
A
D
V
G
T
L
Q
R
L
P
K
V
I
G
N
R
S
L
V
N
E
L
T
F
T
A
R
K
M
M
A
D
E
A
L
D
S
G
L
V
S
R
V
F
P
D
K
D
V
---
M
L
N
A
A
F
A
L
--
A
A
D
I
S
S
K
S
P
V
A
V
Q
G
S
K
I
N
L
I
------
Y
S
R
D
H
S
V
D
E
S
L
D
Y
M
A
T
W
N
M
S
M
L
Q
T
Q
D
I
I
K
S
V
Q
A
A
M
E
K
K
D
55
HHSearch
86.16
24%
-88
* C4 *
-
2PBP
-
?
A:
[11-252]
-----------------------------------------------------------
Q
E
G
A
V
G
I
I
E
L
A
R
P
-
D
V
L
N
A
L
S
R
Q
M
V
A
E
I
V
A
A
V
E
A
F
D
R
N
E
K
V
R
V
I
V
L
T
G
R
-
G
-
R
-
A
F
A
A
G
A
D
I
Q
E
M
A
K
D
D
P
I
------------------
R
L
E
W
-
L
N
Q
F
A
D
W
D
R
L
S
I
V
K
T
P
M
I
A
A
V
N
G
L
A
L
G
G
G
F
E
L
A
L
S
C
D
L
I
V
A
S
-
S
A
A
E
F
G
F
P
E
V
N
--
L
G
V
M
P
G
A
G
G
T
Q
R
L
T
K
L
I
G
P
-
K
R
A
L
E
W
L
W
T
G
A
R
M
S
A
K
E
A
E
Q
L
G
I
V
N
R
V
V
S
P
E
L
----
L
M
E
E
T
M
R
L
--
A
G
R
L
A
E
Q
P
P
L
A
L
R
L
I
K
E
A
V
Q
------
K
A
V
D
Y
P
L
Y
E
G
M
Q
F
E
R
K
N
F
Y
L
L
F
A
S
E
D
Q
K
E
G
M
A
A
F
L
E
K
R
K
5
PsiBlast_PDB
85.99
27%
-90
- C4 -
-
3Q0J
-
ECHA8_MYCTU
A:
[8-236]
--------------------------------------------------------
L
V
E
R
D
Q
R
V
G
I
I
T
L
N
R
P
-
Q
A
L
N
A
L
N
S
Q
V
M
N
E
V
T
S
A
A
T
E
L
D
D
D
P
D
I
G
A
I
I
I
T
G
S
-
A
-
K
-
A
F
A
A
G
A
D
I
K
E
M
A
D
L
-
T
F
--
A
----------
D
----
A
F
T
A
D
F
F
A
T
W
G
K
L
A
A
V
R
T
P
--
T
I
A
A
V
A
G
Y
A
L
G
G
G
C
E
L
A
M
M
C
D
V
L
I
A
A
-
D
T
A
K
F
G
Q
P
E
I
K
--
L
G
V
L
P
G
M
G
G
S
Q
R
L
T
R
A
I
G
K
-
A
K
A
M
D
L
I
L
T
G
R
T
M
D
A
A
E
A
E
R
S
G
L
V
S
R
V
V
P
A
D
D
----
L
L
T
E
A
R
A
T
--
A
T
T
I
S
Q
M
S
A
S
A
A
R
M
A
K
E
A
V
N
------
R
A
F
E
S
S
L
S
E
G
L
L
Y
E
R
R
L
F
H
S
A
F
A
----------------
40
HHSearch
85.93
18%
-58
- C4 -
-
1NZY
2
CBADH_PSEUC
A:
[9-257]
-----------------------------------------------------------
V
E
D
G
V
A
E
I
T
I
K
L
P
-
R
H
R
N
A
L
S
V
K
A
M
Q
E
V
T
D
A
L
N
R
A
E
E
D
D
S
V
G
A
V
M
I
T
G
A
-
E
-
D
-
A
F
C
A
G
F
Y
L
R
E
I
P
L
D
K
G
V
--
A
----------
G
VRDH
F
R
I
A
A
L
W
W
H
Q
M
I
H
K
I
I
R
V
K
R
P
V
L
A
A
I
N
G
V
A
A
G
G
G
L
G
I
S
L
A
S
D
M
A
I
C
A
-
D
S
A
K
F
V
C
A
W
H
T
--
I
G
I
G
N
D
T
A
T
S
Y
S
L
A
R
I
V
G
M
-
R
R
A
M
E
L
M
L
T
N
R
T
L
Y
P
E
E
A
K
D
W
G
L
V
S
R
V
Y
P
K
D
E
----
F
R
E
V
A
W
K
V
--
A
R
E
L
A
A
A
P
T
H
L
Q
V
M
A
K
E
R
F
H
------
A
G
W
M
Q
P
V
E
E
C
T
E
F
E
I
Q
N
V
I
A
S
V
T
H
P
H
F
M
P
C
L
T
R
F
L
D
G
H
R
15
PsiBlast_PDB
85.40
25%
-95
- C4 -
-
4DI1
-
?
A:
[31-248]
------------------------------------------------------------
D
Q
G
L
A
T
L
V
V
S
R
P
-
P
-
T
N
A
M
T
R
Q
V
Y
R
E
I
V
A
A
A
D
E
L
G
R
R
D
D
I
G
A
V
V
L
F
G
G
-
H
-
E
-
I
F
S
A
G
D
D
M
P
E
L
R
T
L
N
A
P
--
E
----------
A
----
D
T
A
A
R
V
R
L
E
-
A
I
D
A
V
A
A
I
P
K
P
T
V
A
A
V
T
G
Y
A
L
G
A
G
L
T
L
A
L
A
A
D
W
R
V
S
G
-
D
N
V
K
F
G
A
T
E
I
L
--
A
G
L
I
P
G
G
G
G
M
G
R
L
T
R
V
V
G
S
-
S
R
A
K
E
L
V
F
S
G
R
F
F
D
A
E
E
A
L
A
L
G
L
I
D
D
M
V
A
P
D
D
V
-
Y
D
S
---
A
V
A
W
--
A
R
R
Y
L
E
C
P
P
R
A
L
A
A
A
K
A
V
I
N
------
D
V
F
E
L
E
A
T
E
R
A
A
A
E
R
------------------------
1
PsiBlast_PDB
83.97
27%
-28
- C4 -
-
5Z7R
-
CRT_CLOAB
A:
[5-237]
-----------------------------------------------------
N
V
I
L
E
K
E
G
K
-
V
A
V
V
T
I
N
R
P
-
K
A
L
N
A
L
N
S
D
T
L
K
E
M
D
Y
V
I
G
E
I
E
N
D
S
E
V
L
A
V
I
L
T
G
A
G
E
-
K
-
S
F
V
A
G
A
D
I
S
E
M
K
E
M
N
T
I
--
E
---------------
G
R
K
F
G
I
L
G
N
K
V
F
R
R
L
E
L
L
E
K
P
V
I
A
A
V
N
G
F
A
L
G
G
G
C
E
I
A
M
S
C
D
I
R
I
A
S
---
S
N
A
R
F
G
Q
P
E
VG
L
G
I
T
P
G
F
G
G
T
Q
R
L
S
R
L
V
G
M
-
G
M
A
K
Q
L
I
F
T
A
Q
N
I
K
A
D
E
A
L
R
I
G
L
V
N
K
V
V
E
P
S
E
----
L
M
N
T
A
K
E
I
--
A
N
K
I
V
S
N
A
P
V
A
V
K
L
S
K
Q
A
I
N
------
R
G
M
Q
C
D
I
D
T
A
L
A
F
E
S
E
A
F
G
E
C
F
-----------------
19
PsiBlast_PDB
82.70
22%
-68
- C4 -
-
4JYL
-
?
A:
[35-262]
-----------------------------------------------------------------
L
I
V
L
S
R
P
-
E
K
L
N
A
I
N
L
E
M
L
A
D
L
A
D
Q
F
S
K
A
E
K
-
E
D
T
R
V
I
V
I
T
G
Y
-
G
-
K
-
N
F
S
A
G
A
D
I
N
M
L
A
S
F
-
D
P
--
A
----------
S
----
A
Y
S
F
R
L
K
M
N
S
I
A
Q
R
I
R
K
S
D
K
P
V
I
A
L
L
K
G
Y
S
M
G
G
G
L
E
L
A
E
S
A
D
I
R
I
A
M
-
S
D
A
V
I
G
Q
P
E
S
S
--
I
G
I
N
A
G
A
G
G
N
V
I
L
P
K
L
V
G
R
-
G
S
A
A
Y
L
A
M
S
G
K
K
L
N
A
Q
E
A
M
A
L
G
L
V
D
E
V
V
D
---------
D
E
A
K
A
W
KI
I
D
D
I
C
K
K
P
K
K
T
L
Q
F
I
K
R
A
I
N
------
S
S
Y
D
M
G
L
E
S
A
M
D
Q
E
A
L
Y
F
S
L
L
F
T
D
P
E
V
L
D
A
L
S
K
------
9
PsiBlast_PDB
82.54
26%
-35
- C4 -
-
5JBX
1
?
A:
[15-230]
---------------------------------------------------------------
I
E
I
W
T
I
D
G
E
-
S
R
R
N
A
I
S
R
A
M
L
K
E
L
G
E
L
V
T
R
V
S
S
S
R
D
V
R
A
V
V
I
T
G
A
-
G
-
D
K
A
F
C
A
G
A
D
L
K
E
R
A
T
M
A
E
D
--
E
----------
V
-----
R
A
F
L
D
G
L
R
R
T
F
R
A
I
E
K
S
D
C
V
F
I
A
A
I
N
G
A
A
L
G
G
G
T
E
L
A
L
A
C
D
L
R
V
A
A
-
P
A
A
E
L
G
L
T
E
V
K
--
L
G
I
I
P
G
G
G
G
T
Q
R
L
A
R
L
V
G
P
-
G
R
A
K
D
L
I
L
T
A
R
R
I
N
A
A
E
A
F
S
V
G
L
A
N
R
L
---
A
P
E
-
G
H
L
L
A
V
A
Y
G
L
--
A
E
S
V
V
E
N
A
P
I
A
V
A
T
A
K
H
A
I
D
------
E
G
T
G
L
E
L
D
D
A
L
A
L
E
-------------------------
51
HHSearch
81.94
21%
-97
- C4 -
-
3FDU
-
?
C:
[11-241]
-----------------------------------------------------------
L
E
G
G
V
L
T
L
A
I
N
R
P
-
E
A
K
N
A
L
Y
G
E
L
Y
L
W
I
A
K
A
L
D
E
A
D
Q
N
K
D
V
R
V
V
V
L
R
G
A
-
E
-
H
-
D
F
T
A
G
N
D
M
K
---------------------------
P
A
G
Q
V
P
P
F
V
L
L
K
S
A
A
R
L
S
K
P
L
I
I
A
V
K
G
V
A
I
G
I
G
V
T
I
L
L
Q
A
D
L
V
F
A
D
-
N
T
A
L
F
Q
I
P
F
V
S
--
L
G
L
S
P
E
G
G
A
S
Q
L
L
V
K
Q
A
G
Y
-
H
K
A
A
E
L
L
F
T
A
K
K
F
N
A
E
T
A
L
Q
A
G
L
V
N
E
I
V
E
D
------
A
Y
A
T
A
Q
A
T
--
A
Q
H
L
T
A
L
P
L
A
S
L
K
Q
T
K
A
L
M
K
------
H
D
L
D
-
Q
I
I
E
C
I
D
H
E
A
E
I
F
M
Q
R
V
Q
S
P
E
M
------------
37
HHSearch
81.65
23%
-15
- C4 -
-
4ZU2
-
?
B:
[13-259]
-----------------------------------------------------------
P
I
E
G
V
L
R
I
T
L
N
R
P
-
Q
S
R
N
A
M
S
L
A
M
V
G
E
L
R
A
V
L
A
A
V
R
D
D
R
S
V
R
A
L
V
L
R
G
A
-
D
-
G
-
H
F
C
A
G
G
D
I
K
D
M
A
G
A
R
A
A
--
G
AE--------
A
----
Y
R
T
L
N
R
A
F
G
S
L
L
E
E
A
Q
A
A
P
Q
L
L
V
A
L
V
E
G
A
V
L
G
G
G
F
G
L
A
C
V
S
D
V
A
I
A
A
-
A
D
A
Q
F
G
L
P
E
T
S
--
L
G
I
L
P
A
Q
I
-
A
P
F
V
V
R
R
I
G
L
-
T
Q
A
R
R
L
A
L
T
A
A
R
F
D
G
R
E
A
L
R
L
G
L
V
H
F
C
E
A
D
A
D
A
---
L
E
Q
R
L
E
E
T
--
L
E
Q
L
R
R
C
A
P
N
A
N
A
A
T
K
A
L
L
L
------
A
S
E
S
G
E
L
G
A
L
L
D
D
A
A
R
Q
F
A
E
A
V
G
G
A
E
G
S
E
G
T
L
A
F
V
Q
K
R
K
6
PsiBlast_PDB
81.04
27%
-89
- C4 -
-
3PZK
-
ECHA8_MYCTU
A:
[7-235]
--------------------------------------------------------
L
V
E
R
D
Q
R
V
G
I
I
T
L
N
R
P
-
Q
A
L
N
A
L
N
S
Q
V
M
N
E
V
T
S
A
A
T
E
L
D
D
D
P
D
I
G
A
I
I
I
T
G
S
-
A
-
K
-
A
F
A
A
G
A
D
I
K
---------------------------
F
T
A
D
F
F
A
T
W
G
K
L
A
A
V
R
T
P
--
T
I
A
A
V
A
G
Y
A
L
G
G
G
C
E
L
A
M
M
C
D
V
L
I
A
A
-
D
T
A
K
F
G
Q
P
E
I
K
--
L
G
V
L
P
G
M
G
G
S
Q
R
L
T
R
A
I
G
K
-
A
K
A
M
D
L
I
L
T
G
R
T
M
D
A
A
E
A
E
R
S
G
L
V
S
R
V
V
P
A
D
D
----
L
L
T
E
A
R
A
T
--
A
T
T
I
S
Q
M
S
A
S
A
A
R
M
A
K
E
A
V
N
------
R
A
F
E
S
S
L
S
E
G
L
L
Y
E
R
R
L
F
H
S
A
F
A
----------------
8
PsiBlast_PDB
81.03
26%
-38
- C4 -
-
5JBW
-
?
A:
[14-229]
---------------------------------------------------------------
I
E
I
W
T
I
D
G
E
-
S
R
R
N
A
I
S
R
A
M
L
K
E
L
G
E
L
V
T
R
V
S
S
S
R
D
V
R
A
V
V
I
T
G
A
-
G
-
D
K
A
F
C
A
G
A
D
L
K
E
R
A
T
M
A
E
D
--
E
----------
V
-----
R
A
F
L
D
G
L
R
R
T
F
R
A
I
E
K
S
D
C
V
F
I
A
A
I
N
G
A
A
L
G
G
G
T
E
L
A
L
A
C
D
L
R
V
A
A
-
P
A
A
E
L
G
L
T
E
V
K
--
L
G
I
I
P
G
G
G
G
T
Q
R
L
A
R
L
V
G
P
-
G
R
A
K
D
L
I
L
T
A
R
R
I
N
A
A
E
A
F
S
V
G
L
A
N
R
L
---
A
P
E
-
G
H
L
L
A
V
A
Y
G
L
--
A
E
S
V
V
E
N
A
P
I
A
V
A
T
A
K
H
A
I
D
------
E
G
T
G
L
E
L
D
D
A
L
A
L
E
-------------------------
44
HHSearch
80.51
18%
-72
- C4 -
-
2VX2
-
ECHD3_HUMAN
D:
[45-295]
---------------------------------------------------
P
R
P
T
S
A
R
-
Q
L
D
G
I
R
N
I
V
L
S
N
P
-
K
K
R
N
T
L
S
L
A
M
L
K
S
L
Q
S
D
I
L
H
D
A
D
S
N
D
L
K
V
I
I
I
S
A
E
-
G
-
P
-
V
F
S
S
G
H
D
L
K
E
L
T
E
E
Q
G
R
--
D
----------
Y
----
H
A
E
V
F
Q
T
C
S
K
V
M
M
H
I
R
N
H
P
V
P
V
I
A
M
V
N
G
L
A
T
A
A
G
C
Q
L
V
A
S
C
D
I
A
V
A
S
-
D
K
S
S
F
A
T
P
G
V
N
--
V
G
L
F
C
S
T
P
G
-
V
A
L
A
R
A
V
P
R
-
K
V
A
L
E
M
L
F
T
G
E
P
I
S
A
Q
E
A
L
L
H
G
L
L
S
K
V
V
P
E
A
E
----
L
Q
E
E
T
M
R
I
--
A
R
K
I
A
S
L
S
R
P
V
V
S
L
G
K
A
T
F
Y
------
K
Q
L
P
Q
D
L
G
T
A
Y
Y
L
T
S
Q
A
M
V
D
N
L
A
L
R
D
G
Q
E
G
I
T
A
F
L
Q
K
R
K