@TOME V3
(Feb 2022)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
3D Alignment Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
3D Alignment Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
PDB Ligands
Affinity Score
Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
Sequence Alignment
Tab of Complexes
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : F120A_HUMAN: (2020-02-01 )
MGVQGFQDYIEKHCPSAVVPVELQKLARGSLVGGGRQRPPQTPLRLLVDADNCLHRLYGGFYTDWVSGGQWNHMLGYLAALAKACFGGNIELFVFFNGALEKARLHEWVKRQGNERQTAQQIVSHVQNKGTPPPKVWFLPPVCMAHCIRLALIRFHVKVAQSIEDHHQEVIGFCRENGFHGLVAYDSDYALCNIPYYFSAHALKLSRNGKSLTTSQYLMHEVAKQLDLNPNRFPIFAALLGNHILPDEDLASFHWSLLGPEHPLASLKVRAHQLVLPPCDVVIKAVADYVRNIQDTSDLDAIAKDVFQHSQSRTDDKVIRFKRAIGYYSATSKPMSFHPPHYLAARPGPFGMPGMVPPHVPPQMLNIPQTSLQAKPVAPQVPSPGGAPGQGPYPYSLSEPAPLTLDTSGKNLTEQNSYSNIPHEGKHTPLYERSSPINPAQSGSPNHVDSAYFPGSSTSSSSDNDEGSGGATNHISGNKIGWEKTGSHSEPQARGDPGDQTKAEGSSTASSGSQLAEGKGSQMGTVQPIPCLLSMPTRNHMDITTPPLPPVAPEVLRVAEHRHKKGLMYPYIFHVLTKGEIKIAVSIEDEANKDLPPAALLYRPVRQYVYGVLFSLAESRKKTERLAFRKNRLPPEFSPVIIKEWAAYKGKSPQTPELVEALAFREWTCPNLKRLWLGKAVEDKNRRMRAFLACMRSDTPAMLNPANVPTHLMVLCCVLRYMVQWPGARILRRQELDAFLAQALSPKLYEPDQLQELKIENLDPRGIQLSALFMSGVDMALFANDACGQPIPWEHCCPWMYFDGKLFQSKLLKASREKTPLIDLCDGQADQAAKVEKMRQSVLEGLSFSRQSHTLPFPPPPALPFYPASAYPRHFGPVPPSQGRGRGFAGVCGFGGPYGETVATGPYRAFRVAAASGHCGAFSGSDSSRTSKSQGGVQPIPSQGGKLEIAGTVVGHWAGSRRGRGGRGPFPLQVVSVGGPARGRPRGVISTPVIRTFGRGGRYYGRGYKNQAAIQGRPPYAASAEEVAKELKSKSGESKSSAMSSDGSLAENGVMAEEKPAPQMNGSTGDARAPSHSESALNNDSKTCNTNPHLNALSTDSACRREAALEAAVLNKEE
Atome Classification :
(20 SA)
---.........10........20.------.......30........40...---.....50........60.------.-----..------.-...70.--.......80........90.-....----------....100.........110.......120.......130----.-----.-----.---.---..-.-.140.----......150.......160.-......170....----...180.......190......------.-200..---.--...--.--210--.........220...-....--.-.230----.......240-...----.....250.......260.......270.......280.......290..----....--.300.......310.......320.......330.......340.......350..---...-----..360.......370.......380.......390.......400.......410.......420.......430.......-440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650.......660.......670.......680.......690.......700.......710.......720.......730.......740.......750.....--..760.......770.......780.......790.......800.......810.......820.......830.......840.......850.......860.......870.......880.......890.......900.....-..910.......920.......930.......940.......--950.......960.......970.......980.......990.......1000......1010......1020......1030......1040......1050......1060......1070......1080..-....1090......1100......1110.....
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
---MG
V
Q
G
F
Q
D
Y
I
E
K
HCPSAV
V
P
V
E
------
L
Q
K
LARGSLVGGGRQRPPQTP
L
---
R
L
L
V
D
A
D
N
C
L
H
R
L
Y
GGF
Y
------
T
-----DW------V-SGGQ
W
N
--
H
M
L
G
Y
L
A
A
L
A
K
A
C
FGG
N
I
-
E
-
L
F
V
F
----------FNGA
L
--
E
K
A
R
L
H
E
W
V
K
RQGN
E
R
Q
T
A
Q
Q
I
V
S
H
V
QNKG-T----P-----P-----
P
---
K
---
V
W
-
F
-L
P
P
V
C
----
M
A
H
C
I
R
L
A
L
I
R
F
H
V
K
V
A
Q
S
I
-
E
D
H
H
Q
E
V
I
G
F
C
R
E----NGF
H
G
L
V
A
YDSDY
A
L
CNI
P
Y
YF------S-
A
H
A
L
K
---L--SRN--G--K----SL
T
T
S
Q
Y
L
M
H
--
E
V
A
-
K
QLD--L-NPNR----
F
P
I
F
A
A
L
LG--NHI----LP
D
E
D
L
A
S
F
H
W
S
LLGPEHP
L
A
S
L
K
V
R
A
H
Q
LVLP
P
C
D
V
V
I
K
A
V
A
D
Y
V
R
NIQ----DT
S
D
--
L
D
A
I
A
K
D
V
F
Q
H
SQSRTD
D
K
V
I
R
F
K
R
A
IGYYSATSKPMSFHPPHYLAARPGPFGMPG---MVP-----PHV
P
P
Q
MLNIPQTSLQAKPVAPQVPSPGGAPGQGPYPYSLSEPA
P
L
T
LDTSGKNLTEQNSYSNIPHEGKHTPLYERSSPINP-AQSGSPNHVDSAYFPGSSTSSSSDNDEGSGGATNHISGNKIGWEKTGSHSEPQARGDPGDQTKAEGSSTASSGSQLAEGKGSQMGTVQPI
P
C
L
LSMPTRNHMDITTPPLPPV
A
P
E
V
L
R
V
A
E
H
R
H
KKGL
M
Y
P
Y
I
F
H
V
LTKG
E
I
K
I
A
V
S
IEDEANKDLP
P
A
A
L
L
Y
R
P
V
R
Q
Y
V
Y
G
V
L
F
S
L
A
E
S
R
K
K
T
E
R
L
A
F
R
KNRLPPEF
S
P
V
I
I
K
E
W
A
AYKGKSPQ
T
P
E
L
V
E
A
L
A
F
REWTC
P
N
L
K
R
L
W
LGKAVED
K
N
R
R
M
R
A
F
L
A
C
M
RSDTPAMLNPANV
P
T
H
L
M
V
L
C
C
V
L
R
Y
M
V
QWP
G
A
R
I
L
R
R
Q
E
L
D
A
F
L
A
Q
ALSPKLYE
P
D
Q
L
Q
E
L
--KIENLDPRG
I
Q
L
S
A
L
F
MSGV
D
M
A
L
F
ANDACGQPI
P
W
E
HCC
P
W
M
YFD
G
K
L
F
Q
S
K
L
L
K
ASREKT
P
L
I
D
LCDGQ
A
D
Q
A
A
K
V
E
K
M
R
Q
S
V
L
E
G
LSFSRQSHTLPFPPPPALPFYPASAYPRHFGPVPPSQGRGRGFAGVCGFGGPYGETVATGP
Y
-
R
A
F
R
V
A
AASGHCGAFSGSDSSRTSKSQGGVQPIPSQG
G
K
L
E
I
--
A
G
T
V
V
G
HWAGSRRGRGGRGP
F
P
L
Q
V
V
SVGGPARGRPRGVIS
T
P
V
I
R
TFGRGGRYYGRGYKNQAAIQGRPPYAA
S
A
E
E
V
A
K
E
L
K
SKSGESKSSAMSSDGSLAENGVMAEEKPAPQMNGSTGDARAPSHSESALNNDS-KTCNTNPH
L
N
ALS
T
D
S
A
C
R
R
E
A
A
L
E
A
A
VLNKEE
43
Fugue
80.91
21%
43
- C4 -
-
5K6L
9
?
A:
[5-798]
KVI
L
D
W
N
E
Y
I
E
A
A
R
S
V
V
S
E
G
C
V
L
L
E
NNGTLP
L
E
K
G
A
V
V
S
I
F
G
-------------------------
R
I
Q
T
H
Y
Y
------
K
-----
S
G
------
T
G
S
G
G
M
V
N
VT
H
V
V
G
V
P
E
G
L
K
L
S
---
E
H
V
-
T
-
V
--------------
N
E
E
L
--
E
N
I
-
Y
K
E
W
E
E
E
N
P
F
D
E
G
L
G
W
---------
G
-
T
----
E
-----
P
--------------
W
-
S
-
Q
P
------------
E
M
E
L
T
D
E
I
V
S
N
A
S
A
K
-
S
D
--
V
A
I
V
I
I
G
R
T
----
A
G
------
E
D
K
D
F
S
D
V
A
G
A
Y
K
L
------
S
-
E
T
E
E
D
---
M
--
L
R
R
--
V
--
R
----
K
H
F
D
K
M
V
V
L
L
--
N
V
G
-
S
L
M
D
--
L
--------------------------------------------
N
V
I
S
E
I
N
P
D
A
L
M
V
I
W
Q
G
G
M
I
G
G
L
G
T
A
D
V
L
T
G
K
V
----
N
P
S
G
KL
T
D
T
I
A
Y
E
I
N
D
Y
P
S
T
E
N
F
G
D
P
V
R
D
Y
Y
A
E
D
I
Y
V
G
Y
R
Y
F
E
T
F
E
K
S
K
V
R
Y
----
P
F
G
Y
G
I
SYT
E
F
E
-----
H
T
V
G
E
F
T
A
D
I
N
S
R
T
F
T
A
S
C
---
T
V
K
N
T
G
S
V
A
G
K
D
V
A
Q
F
Y
V
S
A
P
Q
----
G
K
L
G
K
P
-------------
E
K
V
L
V
A
F
K
K
T
G
I
L
N
P
G
K
E
E
K
I
T
V
T
V
P
F
D
R
F
-------
A
S
F
D
D
T
G
V
T
G
A
E
S
C
F
V
L
------------------
E
A
G
E
Y
T
V
Y
E
G
K
N
V
R
E
S
Y
K
E
----------------
G
S
F
T
L
E
E
N
I
V
T
E
K
L
S
K
A
L
A
P
-
M
E
S
F
K
R
M
K
A
S
E
N
S
D
G
--------
T
L
S
V
K
Y
E
D
V
P
V
S
D
V
D
E
K
K
R
R
L
D
N
M
P
V
E
I
P
Q
D
F
T
A
R
Y
S
-
L
K
D
V
L
S
G
S
V
D
M
E
K
F
I
---
A
R
L
S
D
D
D
L
A
C
I
V
R
G
E
G
--
M
G
S
S
L
V
T
A
G
T
--
A
A
A
F
G
--------------
G
V
S
E
Y
L
R
K
M
D
I
P
A
V
C
C
D
-
D
G
P
S
G
M
R
L
D
S
G
A
T
A
F
-----------
S
M
P
N
G
T
M
L
A
S
T
-----
F
N
P
D
V
I
E
R
M
Y
G
F
T
S
L
E
M
I
YN
K
V
E
C
L
L
G
P
G
M
N
I
H
R
N
P
L
N
G
R
N
F
E
Y
F
S
E
D
--------------
P
Y
L
N
G
T
I
A
-
S
A
M
L
K
G
L
H
K
------------------------------------------------
Y
G
S
D
G
V
A
K
H
F
C
C
N
N
Q
E
L
G
R
Q
A
C
D
S
V
V
-------
S
Q
R
A
L
R
E
I
Y
L
K
G
F
E
I
A
V
K
E
G
G
C
K
A
F
M
T
T
Y
A
Q
V
N
G
M
W
T
A
G
N
Y
D
L
N
T
R
I
L
R
D
E
W
GF
K
G
I
V
M
T
D
W
W
A
Q
V
N
D
R
G
G
E
P
T
---------------------------------------
K
N
N
T
A
A
M
V
R
--------------------------------
A
Q
N
D
L
Y
M
V
T
A
N
A
A
M
--
N
S
A
N
D
N
T
L
S
Q
L
S
E
G
K
L
N
R
A
E
L
Q
R
C
A
M
N
I
C
E
Y
A
M
N
T
-
M
A
M
K
R
L
C
R
N
D
I
K
V
E
I
A
G
R
41
Fugue
59.73
19%
-101
- C4 -
-
4Q0W
-
?
A:
[1-362]
-------
G
V
H
S
F
W
D
I
A
G
P
T
A
-
R
P
V
R
------
L
E
S
L
E
D
K
------------------
R
M
A
V
D
A
S
I
W
I
Y
Q
F
L
K
A
V
R
------
D
-----
Q
---------
N
A
V
K
N
S
--
H
I
T
G
F
F
R
R
I
C
K
L
L
Y
F
G
I
R
-
P
-
V
F
V
F
----------
D
G
G
-----
V
P
V
L
K
R
E
T
I
R
Q
R
K
E
R
R
Q
G
K
R
-----
E
D
E
V
-
T
--------------------------------
M
D
----
M
I
K
E
V
Q
E
L
L
S
R
F
G
I
P
Y
I
T
A
P
-
M
E
A
E
A
Q
C
A
E
L
L
Q
L
----
N
L
V
D
G
I
I
T
D
D
S
D
V
F
L
F
G
G
T
K
I
Y
------
K
-
N
--
M
F
---
H
--
E
K
N
------------
Y
V
E
F
Y
D
A
E
--
S
I
L
-
K
L
L
G
--
L
-
D
R
K
N
----
M
I
E
L
A
Q
L
L
G
--
S
D
-------------
Y
T
N
G
L
K
G
M
G
-
P
V
S
S
I
E
V
I
A
E
F
G
N
L
K
N
F
K
D
W
Y
N
N
G
Q
F
D
K
R
K
Q
E
----
T
E
N
K
--
F
E
K
D
L
R
K
K
L
V
N
N
E
I
I
L
D
D
D
---
F
P
S
V
M
V
Y
D
A
Y
M
R
P
E
V
D
H
D
T
T
P
F
V
W
G
V
P
D
L
D
M
L
R
S
---
F
M
K
TQLGW
P
H
E
K
S
D
E
I
L
I
P
L
I
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
HHSearch
53.39
14%
-78
- C4 -
-
5V07
-
EXO1_HUMAN
Z:
[2-228]
----
G
I
Q
G
L
L
Q
F
I
K
E
A
S
----
E
P
I
H
------
V
R
K
Y
---------------
K
G
Q
---
V
V
A
V
D
T
Y
C
W
L
H
K
G
A
I
A
C
A
------
E
-----
K
L
------
A
-
K
G
E
P
T
D
--
R
Y
V
G
F
C
M
K
F
V
N
M
L
L
S
H
G
I
-
K
-
P
I
L
V
----------
F
D
G
C
T
--
L
P
S
K
K
E
V
E
R
S
R
R
E
R
R
Q
A
N
L
L
K
G
K
Q
L
L
R
E
G
K
-
V
----
S
-----
E
AREC-
F
---
T
---
R
S
-
I
N
I
T
H
A
M
-----
A
H
K
V
I
K
A
A
R
S
Q
G
V
D
C
L
V
A
P
-
Y
E
A
D
A
Q
L
A
Y
L
N
K
A
----
G
I
V
Q
A
I
I
T
E
D
S
A
L
L
A
F
G
C
K
K
V
I
L-----
K
-
M
D
Q
----------
F
--
G
--
N
-------
G
L
E
I
D
Q
A
RL
G
M
C
-
R
Q
L
G
DV
F
-
T
E
E
K
----
F
R
Y
M
C
I
L
S
G
--
C
D
Y
----
L
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
53.02
14%
-58
- C4 -
-
5KSE
-
FEN1_HUMAN
A:
[1-235]
----
G
I
Q
G
L
A
K
L
I
A
D
V
A
P
S
A
I
R
E
N
D
------
I
K
S
Y
F
---------------
G
R
---
K
V
A
I
D
A
S
M
S
I
Y
Q
F
L
I
A
V
R
QGGDV-
L
-----
Q
N
------
E
-
E
G
E
T
T
S
--
H
L
M
G
M
F
Y
R
T
I
R
M
M
-
E
N
G
I
-
K
-
P
V
Y
V
----------
F
D
G
K
P
--
P
Q
L
K
S
G
E
L
A
K
A
S
E
R
R
A
E
A
E
K
Q
L
Q
Q
A
Q
A
A
G
A
-
E
----
Q
EVEKF
T
-----
K
---
R
---
L
V
-
K
-
V
T
K
Q
H
-----
N
D
E
C
K
H
L
L
S
L
M
G
I
P
Y
L
D
A
P
-
S
E
A
E
A
S
C
A
A
L
V
K
A
----
G
K
V
Y
A
A
A
T
E
D
M
D
C
L
T
F
G
S
P
V
L
M
------
R
H
L
T
A
---------
S
E
--
A
--
K
----
K
L
P
I
Q
E
F
H
L
S
--
R
I
L
-
Q
E
L
G
--
L
-
N
Q
E
Q
----
F
V
D
L
C
I
L
L
G
--
S
D
Y
----
C
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
52.43
15%
-125
- C4 -
-
5ZOD
-
?
A:
[2-236]
----
G
I
Q
G
L
A
K
L
I
A
D
V
A
P
S
A
I
R
E
N
D
------
I
K
S
Y
F
---------------
G
R
---
K
V
A
I
D
A
S
M
-------------------------------------
S
--
H
L
M
G
M
F
Y
R
T
I
R
M
M
-
E
N
G
I
-
K
-
P
V
Y
V
----------
F
D
G
K
P
--
P
Q
---------------------------------------------------------------------
N
D
E
C
K
H
L
L
S
L
M
G
I
P
Y
L
D
A
P
-
S
E
A
E
A
S
C
A
A
L
V
K
A
----
G
K
V
Y
A
A
A
T
E
D
M
D
C
L
T
F
G
S
P
V
L
M
R-----
H
-
L
T
A
---------
S
E
--
A
--
K
----
K
L
P
I
Q
E
F
H
L
S
--
R
I
L
-
Q
E
L
G
--
L
-
N
Q
E
Q
----
F
V
D
L
C
I
L
L
G
--
S
D
Y
----
C
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
HHSearch
52.37
16%
-123
* C4 *
-
4Q0Z
-
RAD2_YEAST
A:
[1-246]
----
G
V
H
S
F
W
D
I
A
G
P
T
A
----
R
P
V
R
------
L
E
S
L
E
---------------
D
K
---
R
M
A
V
D
A
S
I
W
I
Y
Q
F
L
K
A
V
R
------
D
-----
Q
E
------
G
-
N
A
V
K
N
S
--
H
I
-
T
G
F
F
R
R
I
C
K
L
L
Y
F
G
I
-
R
-
P
V
F
V
----------
F
D
G
G
V
--
P
V
L
K
R
E
T
I
R
Q
R
K
E
R
R
Q
G
K
R
E
S
A
K
---------------------------------
S
D
-
E
-
V
T
M
D
M
-----
I
K
E
V
Q
E
L
L
S
R
F
G
I
P
Y
I
T
A
P
-
M
E
A
E
A
Q
C
A
E
L
L
Q
L
----
N
L
V
D
G
I
I
T
D
D
S
D
V
F
L
F
G
G
T
K
I
Y
------
K
N
M
F
H
----------------
E
----
K
N
Y
V
E
F
Y
D
A
E
--
S
I
L
-
K
L
L
G
--
L
-
D
R
K
N
----
M
I
E
L
A
Q
L
L
G
--
S
D
Y
----
T
N
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
HHSearch
51.90
17%
-124
- C4 -
-
4Q0W
-
?
A:
[1-246]
----
G
V
H
S
F
W
D
I
A
G
P
T
A
----
R
P
V
R
------
L
E
S
L
E
---------------
D
K
---
R
M
A
V
D
A
S
I
W
I
Y
Q
F
L
K
A
V
R
------
D
-----
Q
---------
N
A
V
K
N
S
--
H
I
T
G
F
F
-
R
R
I
C
K
L
L
Y
F
G
I
-
R
-
P
V
F
V
----------
F
D
G
G
V
--
P
V
L
K
R
E
T
I
R
Q
R
K
E
R
R
Q
G
K
R
E
-------------------------------------
D
-
E
-
V
T
M
D
M
-----
I
K
E
V
Q
E
L
L
S
R
F
G
I
P
Y
I
T
A
P
-
M
E
A
E
A
Q
C
A
E
L
L
Q
L
----
N
L
V
D
G
I
I
T
D
D
S
D
V
F
L
F
G
G
T
K
I
Y
------
K
N
M
F
H
----------------
E
----
K
N
Y
V
E
F
Y
D
A
E
--
S
I
L
-
K
L
L
G
--
L
-
D
R
K
N
----
M
I
E
L
A
Q
L
L
G
--
S
D
Y
----
T
N
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
HHSearch
51.76
14%
-76
- C4 -
-
3QEA
-
EXO1_HUMAN
Z:
[2-228]
----
G
I
Q
G
L
L
Q
F
I
K
E
A
S
----
E
P
I
H
------
V
R
K
Y
---------------
K
G
Q
---
V
V
A
V
D
T
Y
C
W
L
H
K
G
A
I
A
C
A
------
E
-----
K
L
------
A
-
K
G
E
P
T
D
--
R
Y
V
G
F
C
M
K
F
V
N
M
L
L
S
H
G
I
-
K
-
P
I
L
V
----------
F
D
G
C
T
--
L
P
S
K
K
E
V
E
R
S
R
R
E
R
R
Q
A
N
L
L
K
G
K
Q
L
L
R
E
G
K
-
V
----
S
E----
A
REC--
F
---
T
---
R
S
-
I
N
I
T
H
A
M
-----
A
H
K
V
I
K
A
A
R
S
Q
G
V
D
C
L
V
A
P
-
Y
E
A
D
A
Q
L
A
Y
L
N
K
A
----
G
I
V
Q
A
I
I
T
E
D
S
D
L
L
A
F
G
C
K
K
V
I
L-----
K
-
M
D
Q
----------
F
--
G
--
N
----
G
---
L
E
I
D
Q
A
RL
G
M
C
-
R
Q
L
G
DV
F
-
T
E
E
K
----
F
R
Y
M
C
I
L
S
G
--
C
D
Y
----
L
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
HHSearch
51.69
16%
-125
- C4 -
-
5CO8
-
?
A:
[1-258]
----
G
I
K
G
I
Y
K
E
I
G
S
G
-----
E
R
I
S
------
L
C
K
L
A
I
D
H
L
E
------
Q
H
N
R
P
L
---
R
L
A
I
D
M
A
I
W
Q
F
Q
I
Q
A
A
------------------------
R
G
G
S
N
P
--
A
I
R
T
L
F
Y
R
F
V
R
-
L
L
S
L
G
I
-
H
-
P
I
F
V
----------
F
D
G
P
N
--
K
P
--------------------------------------------------
N
----
G
-
V
----------
S
T
A
M
A
K
R
L
I
R
L
F
G
F
T
A
H
D
A
P
-
G
E
A
E
A
E
C
A
Y
L
E
Q
Q
----
G
I
V
D
A
V
L
S
E
D
V
D
T
I
M
F
G
S
R
V
T
L
R-----
D
-
W
S
S
-
E
--------
G
--
G
--
P
----
P
T
H
V
T
L
H
D
A
K
--
K
I
A
E
G
P
S
G
--
L
-
D
R
E
G
----
M
V
L
V
A
L
M
S
G
--
G
D
Y
----
L
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
HHSearch
51.33
16%
-120
- C4 -
-
5CO8
-
?
C:
[1-254]
----
G
I
K
G
I
Y
K
E
I
G
S
G
-----
E
R
I
S
------
L
C
K
L
A
I
D
H
L
E
------
Q
H
N
R
P
L
---
R
L
A
I
D
M
A
I
W
Q
F
Q
I
Q
A
A
------------------------
R
G
G
S
N
P
--
A
I
R
T
L
F
Y
R
F
V
R
-
L
L
S
L
G
I
-
H
-
P
I
F
V
----------
F
D
G
P
N
--
K
P
--------------------------------------------------
N
---
G
--
V
----------
S
T
A
M
A
K
R
L
I
R
L
F
G
F
T
A
H
D
A
P
-
G
E
A
E
A
E
C
A
Y
L
E
Q
Q
----
G
I
V
D
A
V
L
S
E
D
V
D
T
I
M
F
G
S
R
V
T
L
R-----
D
-
W
S
S
-
E
--------
G
--
G
--
P
----
P
T
H
V
T
L
H
D
A
K
--
K
I
A
E
G
P
S
G
--
L
-
D
R
E
G
----
M
V
L
V
A
L
M
S
G
--
G
D
Y
----
L
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
HHSearch
49.45
17%
-9
- C4 -
-
1B43
-
FEN_PYRFU
A:
[1-238]
----
G
V
-
P
I
G
E
I
I
P
R
------
K
E
I
E
------
L
E
N
L
Y
---------------
G
K
---
K
I
A
I
D
A
L
N
A
I
Y
Q
F
L
S
T
I
R
QKDGTP
L
-----
M
D
------
S
-
K
G
R
I
T
S
--
H
L
S
G
L
F
Y
R
T
I
N
-
L
M
E
A
G
I
-
K
-
P
V
Y
V
----------
F
D
G
E
P
--
P
E
F
K
K
K
E
L
E
K
R
R
E
A
R
E
E
A
E
E
K
W
R
E
A
L
E
K
G
E
-
I
----
E
-----
E
ARKYA
Q
---
R
---
A
T
-
R
-
V
N
E
M
L
-----
I
E
D
A
K
K
L
L
E
L
M
G
I
P
I
V
Q
A
P
-
S
E
G
E
A
Q
A
A
Y
M
A
A
K
----
G
S
V
Y
A
S
A
S
Q
D
Y
D
S
L
L
F
G
A
P
R
L
V
------
R
N
L
T
I
-
T
---
G
--
K
R
K
LP
G
--
K
NVYV
E
I
K
P
E
L
I
I
L
E
--
E
V
L
-
K
E
L
K
--
L
-
T
R
E
K
----
L
I
E
L
A
I
L
V
G
--
T
D
Y
----
N
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
42
Fugue
48.97
14%
17
- C4 -
-
1B43
-
FEN_PYRFU
A:
[1-339]
----------------------
G
V
P
------
I
G
E
I
I
P
-------
R
K
E
I
E
L
E
N
L
YGK
K
I
A
I
D
A
L
N
A
I
Y
Q
F
L
S
T
I
R
------
Q
-----
K
D
GTPLMD
S
-
K
G
R
I
T
S
--
H
L
S
G
L
F
Y
R
T
I
N
L
M
E
A
G
I
K
-
P
-
V
Y
V
F
DGEPPEFKKK
E
L
E
K
R
--
R
E
A
R
E
E
A
E
-----------
E
K
W
R
E
A
L
E
K
G
E
-
I
----
E
-----
E
-----
A
---
R
---
K
Y
-
A
-
Q
R
A
T
R
VNEM
L
I
E
D
A
K
K
L
L
E
L
M
G
I
P
I
V
Q
A
P
-
S
E
G
E
A
Q
A
A
Y
M
A
A
K
----
G
S
V
Y
A
S
A
S
Q
D
Y
D
S
L
L
F
G
A
P
R
L
V
RNLTIT
G
-
K
R
K
L
P
---
G
--
K
N
V
--
Y
--
V
----
E
I
K
P
E
L
I
I
L
E
--
E
V
L
-
K
E
L
K
--
L
-
T
R
E
K
----
L
I
E
L
A
I
L
V
G
--
T
D
Y
NPGG
I
K
G
I
G
L
K
K
A
L
E
I
V
R
H
S
K
D
P
L
A
K
F
Q
K
Q
S
D
V
D
L
Y
A
I
K
E
F
F
L
N
P
P
V
T
D
N
Y
N
L
V
WRDP
D
E
E
G
--
I
L
K
F
L
C
D
E
H
D
F
S
E
E
R
V
K
N
G
L
E
R
L
K
K
A
I
K
S
G
K
Q
S
T
L
E
S
W
F
K
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
HHSearch
48.77
17%
-53
- C4 -
-
4WA8
-
FEN_METKA
A:
[8-244]
---
M
G
L
A
E
L
R
E
L
I
E
P
E
------
E
T
D
------
L
R
A
L
A
---------------
G
R
---
E
I
A
I
D
A
F
N
A
L
Y
Q
F
L
T
T
I
M
------
K
DGRPL
M
D
------
S
-
R
G
R
I
T
S
--
H
L
N
G
L
L
Y
R
T
-
V
N
L
V
E
E
G
I
-
K
-
P
V
Y
V
----------
F
D
G
E
P
--
P
D
L
K
---------------------------------------------------------
L
D
E
S
L
-----
V
E
D
A
K
R
L
L
D
L
M
G
I
P
W
V
Q
A
P
-
S
E
G
E
A
Q
C
A
Y
M
A
R
C
----
G
D
V
W
A
T
G
S
Q
D
Y
D
S
L
L
F
G
S
P
R
L
V
------
R
N
I
T
I
V
G
KRK
H
--
P
H
T
--
G
EI
I
----
E
V
K
P
E
I
M
R
L
E
--
D
V
L
-
D
Q
L
G
--
L
E
S
R
E
Q
----
L
V
D
L
A
I
L
L
G
--
T
D
Y
----
N
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
46.71
15%
-45
- C4 -
-
1A76
-
FEN_METJA
A:
[2-227]
----
G
V
-
Q
F
G
D
F
I
P
K
N
------
I
I
S
------
F
E
D
L
---------------
K
G
K
---
K
V
A
I
D
G
M
N
A
L
Y
Q
F
L
T
S
I
R
LRDGSP
L
-----
R
N
------
R
-
K
G
E
I
T
S
--
A
Y
N
G
V
F
Y
K
T
I
-
H
L
L
E
N
D
I
-
T
-
P
I
W
V
----------
F
D
G
E
P
--
P
K
L
K
E
K
T
R
K
V
R
R
E
M
K
E
K
A
E
L
K
M
K
E
A
I
K
K
E
D
F
E
EAAK
Y
-----
A
-----
K
---
R
---
V
S
-
Y
-
L
T
P
K
M
-----
V
E
N
C
K
Y
L
L
S
L
M
G
I
P
Y
V
E
A
P
-
S
E
G
E
A
Q
A
S
Y
M
A
K
K
----
G
D
V
W
A
V
V
S
Q
D
Y
D
A
L
L
Y
G
A
P
R
V
V
------
R
N
L
T
T
----------
T
----------
K
E
M
P
E
L
I
E
L
N
--
E
V
L
-
E
D
L
R
--
I
-
S
L
D
D
----
L
I
D
I
A
I
F
M
G
--
T
D
Y
----
N
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
HHSearch
46.58
16%
-24
- C4 -
-
3ORY
-
?
A:
[11-253]
---
M
G
V
-
D
L
K
D
I
I
P
G
E
A
K
T
V
I
--
E
D
------
L
R
I
L
---------------
H
G
K
---
I
I
V
I
D
G
Y
N
A
L
Y
Q
F
L
A
A
I
R
QPDGTP
L
-----
M
D
------
N
-
N
G
R
I
T
S
--
H
L
S
G
L
F
Y
R
T
I
N
-
I
V
E
A
G
I
-
K
-
P
V
Y
V
----------
F
D
G
K
P
--
P
E
L
K
A
R
E
I
E
R
R
K
A
V
K
E
E
A
A
K
K
Y
E
E
A
V
Q
-
S
G
-
D
----
L
-----
E
LA---
R
---
R
YAM
M
S
A
K
-
L
T
E
E
M
-----
V
R
D
A
K
S
L
L
D
A
M
G
I
P
W
V
Q
A
P
-
A
E
G
E
A
Q
A
A
Y
I
V
K
K
----
G
D
A
Y
A
S
A
S
Q
D
Y
D
S
L
L
F
G
S
P
K
L
V
------
R
N
L
T
I
S
G
RRK
L
PR
K
N
E
--
Y
--
V
----
E
V
K
P
E
L
I
E
L
D
--
K
L
L
-
V
Q
L
G
--
I
-
T
L
E
N
----
L
I
D
I
G
I
L
L
G
--
T
D
Y
----
N
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
HHSearch
46.50
14%
-23
- C4 -
-
1RXW
-
FEN_ARCFU
A:
[3-242]
-----
A
-
D
I
G
D
L
F
E
R
------
E
E
V
E
------
L
E
Y
F
S
---------------
G
K
---
K
I
A
V
D
A
F
N
T
L
Y
Q
F
I
S
I
I
R
QPDGTP
L
-----
K
D
------
S
-
Q
G
R
I
T
S
--
H
L
S
-
G
I
L
Y
R
V
S
N
M
V
E
V
G
I
-
R
-
P
V
F
V
----------
F
D
G
E
P
--
P
E
F
K
K
A
E
I
E
E
R
K
K
R
R
A
E
A
E
E
M
W
I
A
A
L
Q
A
G
D
-
K
----
D
-----
A
-----
K
KYA
Q
---
A
A
-
G
-
R
V
D
E
Y
----
I
V
D
S
A
K
T
L
L
S
Y
M
G
I
P
F
V
D
A
P
-
S
E
G
E
A
Q
A
A
Y
M
A
A
K
----
G
D
V
E
Y
T
G
S
Q
D
Y
D
S
L
L
F
G
S
P
R
L
A
------
R
N
L
A
I
---------------------
D
V
K
P
E
I
I
I
L
E
--
S
N
L
-
K
R
L
G
--
L
-
T
R
E
Q
----
L
I
D
I
A
I
L
V
G
--
T
D
Y
----
N
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
38
HHSearch
43.52
16%
-66
- C4 -
-
3ZDB
-
XNI_ECOLI
A:
[3-180]
---------------------------------------------------
V
H
---
L
L
I
V
D
A
L
N
L
I
R
R
I
H
A
V
-------------------------
Q
G
S
P
C
---
V
E
T
C
Q
H
A
L
D
Q
L
I
M
H
S
Q
P
T
H
-
A
V
A
V
----------
F
D
D
--S-
S
G
W
R
H
Q
R
L
P
D
Y
K
---------------
A
G
R
-
P
----
P
-----
M
-----
P
---
E
---
E
----
L
-
H
D
E
-----
M
P
A
L
R
A
A
F
E
Q
R
G
V
P
C
W
S
T
S
G
N
E
A
D
D
L
A
A
T
L
A
V
K
VTQA
G
H
Q
A
T
I
V
S
T
D
K
G
Y
C
Q
L
L
S
P
T
L
R
------
I
-
R
D
----------------------
Y
F
Q
K
R
W
L
D
A
P
--
F
I
D
-
K
E
F
G
--
V
-
Q
P
Q
Q
----
L
P
D
Y
W
G
L
A
G
IS
S
S
K
----
V
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
39
HHSearch
43.24
16%
-72
- C4 -
-
3ZD9
-
XNI_ECOLI
A:
[3-180]
---------------------------------------------------
V
H
---
L
L
I
V
D
A
L
N
L
I
R
R
I
H
A
V
-------------------------
Q
G
S
P
C
---
V
E
T
C
Q
H
A
L
D
Q
L
I
M
H
S
Q
P
T
H
-
A
V
A
V
----------
F
D
D
E
N
RS
S
G
W
R
H
Q
R
L
P
D
Y
K
---------------
A
G
R
-
P
----
P
-----
M
-----
P
---
E
---
E
----
L
-
H
D
E
-----
M
P
A
L
R
A
A
F
E
Q
R
G
V
P
C
W
S
T
S
G
N
E
A
D
D
L
A
A
T
L
A
V
K
VTQA
G
H
Q
A
T
I
V
S
T
D
K
G
Y
C
Q
L
L
S
P
T
L
R
------
I
-
R
D
----------------------
Y
F
Q
K
R
W
L
D
A
P
--
F
I
D
-
K
E
F
G
--
V
-
Q
P
Q
Q
----
L
P
D
Y
W
G
L
A
G
IS
S
S
K
----
V
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
HHSearch
41.27
18%
-24
- C4 -
-
6C36
-
?
A:
[3-211]
---------------------------------------------------
A
P
---
I
L
L
L
D
G
A
S
M
W
F
R
S
Y
F
G
V
P
------
S
SI---
K
A
------
P
-
D
G
R
P
V
N
--
A
V
R
G
F
I
D
A
I
S
T
L
V
T
R
E
K
P
-
R
R
L
V
V
C
----------
R
D
D
D
W
--
R
P
Q
W
R
V
D
L
I
P
S
Y
K
A
H
R
V
A
E
P
E
P
D
G
V
-
P
D
I
E
-----------------------------
E
-
V
P
D
D
L
TP--
Q
V
N
M
I
L
E
L
L
D
A
F
G
I
P
T
A
G
A
A
G
F
E
A
D
D
V
L
G
T
L
S
A
R
EE--
R
D
P
V
V
V
V
S
G
D
R
D
L
L
Q
L
V
R
D
E
P
A
------
P
Q
V
R
V
L
Y
---
L
--
G
R
------
G
----
L
A
K
A
T
K
W
G
P
A
--
E
V
A
-
E
Q
Y
G
--
V
-
P
L
D
R
AGTA
Y
A
E
L
A
L
L
R
G
DP
S
N
G
----
L
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
HHSearch
40.53
13%
-45
- C4 -
-
2IZO
-
FEN_SACS2
A:
[18-254]
---------------------------------------------------
G
K
---
R
V
S
I
D
G
Y
N
A
L
Y
Q
F
L
A
A
I
R
QPP---
L
-----
M
D
------
S
-
Q
G
R
V
T
S
--
H
L
S
G
L
F
Y
R
T
I
N
I
L
-
E
E
G
V
-
I
-
P
I
Y
V
----------
F
D
G
------------------------------------------------------------------
S
N
I
M
-----
V
E
E
S
K
K
L
L
R
A
M
G
I
P
I
V
Q
A
P
-
S
E
G
E
A
E
A
A
Y
L
N
K
L
----
G
L
S
W
A
A
A
S
Q
D
Y
D
A
I
L
F
G
A
K
R
L
V
------
R
-
N
L
T
I
-------------Y-
V
----
E
I
K
P
E
L
I
E
T
E
--
I
L
L
-
K
K
L
G
--
I
-
T
R
E
Q
----
L
I
D
I
G
I
L
I
G
--
T
D
Y
----
N
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------