@TOME V3
(Feb 2022)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
3D Alignment Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
3D Alignment Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
PDB Ligands
Affinity Score
Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
Sequence Alignment
Tab of Complexes
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : FRIL_HUMAN: (2020-02-01 )
MSSQIRQNYSTDVEAAVNSLVNLYLQASYTYLSLGFYFDRDDVALEGVSHFFRELAEEKREGYERLLKMQNQRGGRALFQDIKKPAEDEWGKTPDAMKAAMALEKKLNQALLDLHALGSARTDPHLCDFLETHFLDEEVKLIKKMGDHLTNLHRLGGPEAGLGEYLFERLTLKHD
Atome Classification :
(21 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130-.......140.......150.......160.......170...
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MS
S
Q
I
R
Q
NYS
T
D
V
E
A
A
V
N
S
L
V
N
L
Y
L
Q
A
S
Y
T
Y
L
S
L
G
F
Y
FDR
D
D
V
A
L
E
G
V
S
H
F
F
R
E
L
A
E
E
K
R
E
G
Y
E
R
L
L
K
M
QNQRG
G
R
A
L
F
Q
D
I
KKPAEDEWGK
T
P
D
A
M
K
A
A
M
A
L
E
K
K
L
N
Q
A
L
L
D
L
H
A
LGSARTD
P
H
L
C
D
F
L
E
T
-HF
L
D
E
E
V
K
L
I
K
K
M
G
D
H
L
T
N
L
H
RLGGPE
A
G
L
G
E
Y
L
F
E
R
LTLKHD
3
PsiBlast_PDB
100.00
100%
0
- C- -
-
2FG8
-
FRIL_HUMAN
A:
[1-174]
-
S
S
Q
I
R
Q
N
Y
S
T
D
V
E
A
A
V
N
S
L
V
N
L
Y
L
Q
A
S
Y
T
Y
L
S
L
G
F
Y
F
D
R
D
D
V
A
L
E
G
V
S
H
F
F
R
E
L
A
E
E
K
R
E
G
Y
E
R
L
L
K
M
Q
N
Q
R
G
G
R
A
L
F
Q
D
I
K
K
P
A
E
D
E
W
G
K
T
P
D
A
M
K
A
A
M
A
L
E
K
K
L
N
Q
A
L
L
D
L
H
A
L
G
S
A
R
T
D
P
H
L
C
D
F
L
E
T
-
H
F
L
D
E
E
V
K
L
I
K
K
M
G
D
H
L
T
N
L
H
R
L
G
G
P
E
A
G
L
G
E
Y
L
F
E
R
L
T
L
K
H
D
4
PsiBlast_PDB
95.78
100%
-93
- C3 -
-
2FFX
-
FRIL_HUMAN
J:
[1-173]
-
S
S
Q
I
R
Q
N
Y
S
T
D
V
E
A
A
V
N
S
L
V
N
L
Y
L
Q
A
S
Y
T
Y
L
S
L
G
F
Y
F
D
R
D
D
V
A
L
E
G
V
S
H
F
F
R
E
L
A
E
E
K
R
E
G
Y
E
R
L
L
K
M
Q
N
Q
R
G
G
R
A
L
F
Q
D
I
K
K
P
A
E
D
E
W
G
K
T
P
D
A
M
K
A
A
M
A
L
E
K
K
L
N
Q
A
L
L
D
L
H
A
L
G
S
A
R
T
D
P
H
L
C
D
F
L
E
T
-
H
F
L
D
E
E
V
K
L
I
K
K
M
G
D
H
L
T
N
L
H
R
L
G
G
P
E
A
G
L
G
E
Y
L
F
E
R
L
T
L
K
H
-
1
PsiBlast_PDB
95.60
100%
-92
- C3 -
-
5LG8
1
FRIL_HUMAN
A:
[3-175]
--
S
Q
I
R
Q
N
Y
S
T
D
V
E
A
A
V
N
S
L
V
N
L
Y
L
Q
A
S
Y
T
Y
L
S
L
G
F
Y
F
D
R
D
D
V
A
L
E
G
V
S
H
F
F
R
E
L
A
E
E
K
R
E
G
Y
E
R
L
L
K
M
Q
N
Q
R
G
G
R
A
L
F
Q
D
I
K
K
P
A
E
D
E
W
G
K
T
P
D
A
M
K
A
A
M
A
L
E
K
K
L
N
Q
A
L
L
D
L
H
A
L
G
S
A
R
T
D
P
H
L
C
D
F
L
E
T
-
H
F
L
D
E
E
V
K
L
I
K
K
M
G
D
H
L
T
N
L
H
R
L
G
G
P
E
A
G
L
G
E
Y
L
F
E
R
L
T
L
K
H
D
2
PsiBlast_PDB
94.68
100%
-98
- C3 -
-
2FG4
-
FRIL_HUMAN
A:
[1-171]
-
S
S
Q
I
R
Q
N
Y
S
T
D
V
E
A
A
V
N
S
L
V
N
L
Y
L
Q
A
S
Y
T
Y
L
S
L
G
F
Y
F
D
R
D
D
V
A
L
E
G
V
S
H
F
F
R
E
L
A
E
E
K
R
E
G
Y
E
R
L
L
K
M
Q
N
Q
R
G
G
R
A
L
F
Q
D
I
K
K
P
A
E
D
E
W
G
K
T
P
D
A
M
K
A
A
M
A
L
E
K
K
L
N
Q
A
L
L
D
L
H
A
L
G
S
A
R
T
D
P
H
L
C
D
F
L
E
T
-
H
F
L
D
E
E
V
K
L
I
K
K
M
G
D
H
L
T
N
L
H
R
L
G
G
P
E
A
G
L
G
E
Y
L
F
E
R
L
T
L
---
14
PsiBlast_PDB
92.37
87%
-104
- C3 -
-
2V2N
3
FRIL_HORSE
A:
[1-171]
-
S
S
Q
I
R
Q
N
Y
S
T
E
V
E
A
A
V
N
R
L
V
N
L
Y
L
R
A
S
Y
T
Y
L
S
L
G
F
Y
F
D
R
D
D
V
A
L
E
G
V
C
H
F
F
R
E
L
A
E
E
K
M
E
G
A
E
R
L
L
K
M
Q
N
Q
R
G
G
R
A
L
F
Q
D
L
Q
K
P
S
Q
D
E
W
G
T
T
P
D
A
M
K
A
A
I
V
L
E
K
S
L
N
Q
A
L
L
D
L
H
A
L
G
S
A
Q
A
D
P
H
L
C
D
F
L
E
S
-
H
F
L
D
E
E
V
K
L
I
K
K
M
G
D
H
L
T
N
I
Q
R
L
V
G
S
Q
A
G
L
G
E
Y
L
F
E
R
L
T
L
---
13
PsiBlast_PDB
92.37
87%
-97
- C3 -
-
3H7G
4
FRIL_HORSE
A:
[2-174]
--
S
Q
I
R
Q
N
Y
S
T
E
V
E
A
A
V
N
R
L
V
N
L
Y
L
R
A
S
Y
T
Y
L
S
L
G
F
Y
F
D
R
D
D
V
A
L
E
G
V
C
H
F
F
R
E
L
A
E
E
K
R
E
G
A
E
R
L
L
K
M
Q
N
Q
R
G
G
-
A
L
F
Q
D
L
Q
K
P
S
Q
D
E
W
G
T
T
P
D
A
M
K
A
A
I
V
L
E
K
S
L
N
Q
A
L
L
D
L
H
A
L
G
S
A
Q
A
D
P
H
L
C
D
F
L
E
S
-
H
F
L
D
E
E
V
K
L
I
K
K
M
G
D
H
L
T
N
I
Q
R
L
V
G
S
Q
A
G
L
G
E
Y
L
F
E
R
L
T
L
K
H
D
11
PsiBlast_PDB
92.31
87%
-100
- C3 -
-
1DAT
-
FRIL_HORSE
A:
[1-174]
-
S
S
Q
I
R
Q
N
Y
S
T
E
V
E
A
A
V
N
R
L
V
N
L
Y
L
R
A
S
Y
T
Y
L
S
L
G
F
Y
F
D
R
D
D
V
A
L
E
G
V
C
H
F
F
R
E
L
A
E
E
K
R
E
G
A
E
R
L
L
K
M
Q
N
Q
R
G
G
R
A
L
F
Q
D
L
Q
K
P
S
Q
D
E
W
G
T
T
P
D
A
M
K
A
A
I
V
L
E
K
S
L
N
Q
A
L
L
D
L
H
A
L
G
S
A
Q
A
D
P
H
L
C
D
F
L
E
S
-
H
F
L
D
E
E
V
K
L
I
K
K
M
G
D
H
L
T
N
I
Q
R
L
V
G
S
Q
A
G
L
G
E
Y
L
F
E
R
L
T
L
K
H
D
16
PsiBlast_PDB
91.85
87%
-105
- C3 -
-
2V2S
2
FRIL_HORSE
A:
[1-171]
-
S
S
Q
I
R
Q
N
Y
S
T
E
V
E
A
A
V
N
R
L
V
N
L
Y
L
R
A
S
Y
T
Y
L
S
L
G
F
Y
F
D
R
D
D
V
A
L
E
G
V
C
H
F
F
R
E
L
A
E
E
K
M
E
G
A
E
R
L
L
K
M
Q
N
Q
R
G
G
R
A
L
F
Q
D
L
Q
K
P
S
Q
D
E
W
G
T
T
P
D
A
M
K
A
A
I
V
L
E
K
S
L
N
Q
A
L
L
D
L
H
A
L
G
S
A
Q
A
D
P
H
L
C
D
F
L
E
S
-
H
F
L
D
E
E
V
K
L
I
K
K
M
G
D
H
L
T
N
I
Q
R
L
V
G
S
Q
A
G
L
G
E
Y
L
F
E
R
L
T
L
---
8
PsiBlast_PDB
91.83
88%
-104
- C3 -
-
2V2J
5
FRIL_HORSE
A:
[3-172]
--
S
Q
I
R
Q
N
Y
S
T
E
V
E
A
A
V
N
R
L
V
N
L
Y
L
R
A
S
Y
T
Y
L
S
L
G
F
Y
F
D
R
D
D
V
A
L
E
G
V
C
H
F
F
R
E
L
A
E
E
K
R
E
G
A
E
R
L
L
K
M
Q
N
Q
R
G
G
R
A
L
F
Q
D
L
Q
K
P
S
Q
D
E
W
G
T
T
P
D
A
M
K
A
A
I
V
L
E
K
S
L
N
Q
A
L
L
D
L
H
A
L
G
S
A
Q
A
D
P
H
L
C
D
F
L
E
S
-
H
F
L
D
E
E
V
K
L
I
K
K
M
G
D
H
L
T
N
I
Q
R
L
V
G
S
Q
A
G
L
G
E
Y
L
F
E
R
L
T
L
---
12
PsiBlast_PDB
91.63
87%
-102
- C3 -
-
2Z5P
3
FRIL_HORSE
A:
[1-171]
-
S
S
Q
I
R
Q
N
Y
S
T
E
V
E
A
A
V
N
R
L
V
N
L
Y
L
R
A
S
Y
T
Y
L
S
L
G
F
Y
F
D
R
D
D
V
A
L
E
G
V
C
H
F
F
R
E
L
A
E
E
K
R
E
G
A
E
R
L
L
K
M
Q
N
Q
R
G
G
R
A
L
F
Q
D
L
Q
K
P
S
Q
D
E
W
G
T
T
P
D
A
M
K
A
A
I
V
L
E
K
S
L
N
Q
A
L
L
D
L
H
A
L
G
S
A
Q
A
D
P
H
L
C
D
F
L
E
S
-
H
F
L
D
E
E
V
K
L
I
K
K
M
G
D
H
L
T
N
I
Q
R
L
V
G
S
Q
A
G
L
G
E
Y
L
F
E
R
L
T
L
---
19
PsiBlast_PDB
91.54
87%
-102
- C3 -
-
3FI6
-
FRIL_HORSE
A:
[2-173]
--
S
Q
I
R
Q
N
Y
S
T
E
V
E
A
A
V
N
R
L
V
N
L
Y
L
R
A
S
Y
T
Y
L
S
L
G
F
Y
F
D
R
D
D
V
A
L
E
G
V
C
A
F
F
R
E
L
A
E
E
K
R
E
G
A
E
R
L
L
K
M
Q
N
Q
R
G
G
R
A
L
F
Q
D
L
Q
K
P
S
Q
D
E
W
G
T
T
P
D
A
M
K
A
A
I
V
L
E
K
S
L
N
Q
A
L
L
D
L
H
A
L
G
S
A
Q
A
D
P
H
L
C
D
F
L
E
S
-
H
F
L
D
E
E
V
K
L
I
K
K
M
G
D
H
L
T
N
I
Q
R
L
V
G
S
Q
A
G
L
G
E
Y
L
F
E
R
L
T
L
K
H
-
7
PsiBlast_PDB
91.53
88%
-106
- C3 -
-
2V2I
1
FRIL_HORSE
A:
[3-172]
--
S
Q
I
R
Q
N
Y
S
T
E
V
E
A
A
V
N
R
L
V
N
L
Y
L
R
A
S
Y
T
Y
L
S
L
G
F
Y
F
D
R
D
D
V
A
L
E
G
V
C
H
F
F
R
E
L
A
E
E
K
R
E
G
A
E
R
L
L
K
M
Q
N
Q
R
G
G
R
A
L
F
Q
D
L
Q
K
P
S
Q
D
E
W
G
T
T
P
D
A
M
K
A
A
I
V
L
E
K
S
L
N
Q
A
L
L
D
L
H
A
L
G
S
A
Q
A
D
P
H
L
C
D
F
L
E
S
-
H
F
L
D
E
E
V
K
L
I
K
K
M
G
D
H
L
T
N
I
Q
R
L
V
G
S
Q
A
G
L
G
E
Y
L
F
E
R
L
T
L
---
18
PsiBlast_PDB
91.30
87%
-102
- C3 -
-
2ZG8
10
FRIL_HORSE
X:
[1-173]
-
S
S
Q
I
R
Q
N
Y
S
T
E
V
E
A
A
V
N
R
L
V
N
L
Y
L
R
A
S
Y
T
Y
L
S
L
G
F
Y
F
D
R
D
D
V
A
L
E
G
V
C
A
F
F
R
E
L
A
E
E
K
R
E
G
A
E
R
L
L
K
M
Q
N
Q
R
G
G
R
A
L
F
Q
D
L
Q
K
P
S
Q
D
E
W
G
T
T
P
D
A
M
K
A
A
I
V
L
E
K
S
L
N
Q
A
L
L
D
L
H
A
L
G
S
A
Q
A
D
P
H
L
C
D
F
L
E
S
-
H
F
L
D
E
E
V
K
L
I
K
K
M
G
D
H
L
T
N
I
Q
R
L
V
G
S
Q
A
G
L
G
E
Y
L
F
E
R
L
T
L
K
H
-
15
PsiBlast_PDB
91.29
87%
-104
- C3 -
-
2V2O
1
FRIL_HORSE
A:
[1-171]
-
S
S
Q
I
R
Q
N
Y
S
T
E
V
E
A
A
V
N
R
L
V
N
L
Y
L
R
A
S
Y
T
Y
L
S
L
G
F
Y
F
D
R
D
D
V
A
L
E
G
V
C
H
F
F
R
E
L
A
E
E
K
M
E
G
A
E
R
L
L
K
M
Q
N
Q
R
G
G
R
A
L
F
Q
D
L
Q
K
P
S
Q
D
E
W
G
T
T
P
D
A
M
K
A
A
I
V
L
E
K
S
L
N
Q
A
L
L
D
L
H
A
L
G
S
A
Q
A
D
P
H
L
C
D
F
L
E
S
-
H
F
L
D
E
E
V
K
L
I
K
K
M
G
D
H
L
T
N
I
Q
R
L
V
G
S
Q
A
G
L
G
E
Y
L
F
E
R
L
T
L
---
20
PsiBlast_PDB
91.15
87%
-100
- C3 -
-
3O7R
5
FRIL_HORSE
A:
[1-173]
-
S
S
Q
I
R
Q
N
Y
S
T
E
V
E
A
A
V
N
R
L
V
N
L
Y
L
R
A
S
Y
T
Y
L
S
L
G
F
Y
F
D
R
D
D
V
A
L
E
G
V
C
A
F
F
R
E
L
A
E
E
K
R
E
G
A
E
R
L
L
K
M
Q
N
Q
R
G
G
R
A
L
F
Q
D
L
Q
K
P
S
Q
D
E
W
G
T
T
P
D
A
M
K
A
A
I
V
L
E
K
S
L
N
Q
A
L
L
D
L
H
A
L
G
S
A
Q
A
D
P
H
L
C
D
F
L
E
S
-
H
F
L
D
E
E
V
K
L
I
K
K
M
G
D
H
L
T
N
I
Q
R
L
V
G
S
Q
A
G
L
G
E
Y
L
F
E
R
L
T
L
K
H
-
10
PsiBlast_PDB
91.11
87%
-107
- C3 -
-
1AEW
-
FRIL_HORSE
A:
[2-171]
--
S
Q
I
R
Q
N
Y
S
T
E
V
E
A
A
V
N
R
L
V
N
L
Y
L
R
A
S
Y
T
Y
L
S
L
G
F
Y
F
D
R
D
D
V
A
L
E
G
V
C
H
F
F
R
E
L
A
E
E
K
R
E
G
A
E
R
L
L
K
M
Q
N
Q
R
G
G
R
A
L
F
Q
D
L
Q
K
P
S
Q
D
E
W
G
T
T
P
D
A
M
K
A
A
I
V
L
E
K
S
L
N
Q
A
L
L
D
L
H
A
L
G
S
A
Q
A
D
P
H
L
C
D
F
L
E
S
-
H
F
L
D
E
E
V
K
L
I
K
K
M
G
D
H
L
T
N
I
Q
R
L
V
G
S
Q
A
G
L
G
E
Y
L
F
E
R
L
T
L
---
9
PsiBlast_PDB
91.10
87%
-106
- C3 -
-
2G4H
-
FRIL_HORSE
A:
[2-171]
--
S
Q
I
R
Q
N
Y
S
T
E
V
E
A
A
V
N
R
L
V
N
L
Y
L
R
A
S
Y
T
Y
L
S
L
G
F
Y
F
D
R
D
D
V
A
L
E
G
V
C
H
F
F
R
E
L
A
E
E
K
R
E
G
A
E
R
L
L
K
M
Q
N
Q
R
G
G
R
A
L
F
Q
D
L
Q
K
P
S
Q
D
E
W
G
T
T
P
D
A
M
K
A
A
I
V
L
E
K
S
L
N
Q
A
L
L
D
L
H
A
L
G
S
A
Q
A
D
P
H
L
C
D
F
L
E
S
-
H
F
L
D
E
E
V
K
L
I
K
K
M
G
D
H
L
T
N
I
Q
R
L
V
G
S
Q
A
G
L
G
E
Y
L
F
E
R
L
T
L
---
6
PsiBlast_PDB
90.72
88%
-100
- C3 -
-
2ZA6
-
FRIL_HORSE
A:
[2-172]
-
S
S
Q
I
R
Q
N
Y
S
T
E
V
E
A
A
V
N
R
L
V
N
L
Y
L
R
A
S
Y
T
Y
L
S
L
G
F
Y
F
D
R
D
D
V
A
L
E
G
V
C
H
F
F
R
E
L
A
E
E
K
R
E
G
A
E
R
L
L
K
M
Q
N
Q
R
G
G
R
A
L
F
Q
D
L
Q
K
P
S
Q
D
E
W
G
T
T
P
D
A
M
K
A
A
I
V
L
E
K
S
L
N
Q
A
L
L
D
L
H
A
L
G
S
A
Q
A
D
P
H
L
C
D
F
L
E
S
-
H
F
L
D
E
E
V
K
L
I
K
K
M
G
D
H
L
T
N
I
Q
R
L
V
G
S
Q
A
G
L
G
E
Y
L
F
E
R
L
T
L
---
17
PsiBlast_PDB
90.45
87%
-101
- C3 -
-
3AF9
8
FRIL_HORSE
X:
[2-172]
--
S
Q
I
R
Q
N
Y
S
T
E
V
E
A
A
V
N
R
L
V
N
L
Y
L
R
A
S
Y
T
Y
L
S
L
G
F
Y
F
D
R
D
D
V
A
L
E
G
V
A
H
F
F
R
E
L
A
E
E
K
R
E
G
A
E
R
L
L
K
M
Q
N
Q
R
G
G
R
A
L
F
Q
D
L
Q
K
P
S
Q
D
E
W
G
T
T
L
D
A
M
K
A
A
I
V
L
E
K
S
L
N
Q
A
L
L
D
L
H
A
L
G
S
A
Q
A
D
P
H
L
C
D
F
L
E
S
-
H
F
L
D
E
E
V
K
L
I
K
K
M
G
D
H
L
T
N
I
Q
R
L
V
G
S
Q
A
G
L
G
E
Y
L
F
E
R
L
T
L
K
--
47
HHSearch
90.00
86%
-70
- C3 -
-
3NOZ
15
FRIL_HORSE
X:
[1-174]
-
S
S
Q
I
R
Q
N
Y
S
T
E
V
E
A
A
V
N
R
L
V
N
L
Y
L
R
A
S
Y
T
Y
L
S
L
G
F
Y
F
D
R
D
D
V
A
L
C
G
V
C
H
F
F
H
E
L
A
E
E
K
R
E
G
A
E
R
L
L
K
M
Q
N
Q
R
G
G
R
A
L
F
Q
D
L
Q
K
P
S
Q
D
E
W
G
T
T
L
D
A
M
K
A
A
I
V
L
E
K
S
L
N
Q
A
L
L
D
L
H
A
L
G
S
A
Q
A
D
P
H
L
C
D
F
L
-
E
S
H
F
L
D
E
E
V
K
L
I
K
K
M
G
D
H
L
T
N
I
Q
R
L
V
G
S
Q
A
G
L
G
E
Y
L
F
E
R
L
T
L
K
H
D
41
HHSearch
88.73
85%
-85
- C3 -
-
2V2P
2
FRIL_HORSE
A:
[2-171]
--
S
Q
I
R
Q
N
Y
S
T
E
V
E
A
A
V
N
R
L
V
N
L
Y
L
R
A
S
Y
T
Y
L
S
L
G
F
Y
F
D
R
D
D
V
A
L
E
G
V
C
H
F
F
R
Q
L
A
Q
Q
K
M
Q
G
A
E
R
L
L
K
M
Q
N
Q
R
G
G
R
A
L
F
Q
D
L
Q
K
P
S
Q
D
E
W
G
T
T
P
D
A
M
K
A
A
I
V
L
E
K
S
L
N
Q
A
L
L
D
L
H
A
L
G
S
A
Q
A
D
P
H
L
C
D
F
L
-
E
S
H
F
L
D
E
E
V
K
L
I
K
K
M
G
D
H
L
T
N
I
Q
R
L
V
G
S
Q
A
G
L
G
E
Y
L
F
E
R
L
T
L
---