@TOME V3
(Feb 2022)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
3D Alignment Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
3D Alignment Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
PDB Ligands
Affinity Score
Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
Sequence Alignment
Tab of Complexes
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : GAL3B_HUMAN: (2020-02-01 )
MAAVRALVASRLAAASAFTSLSPGGRTPSQRAALHLSVPRPAARVALVLSGCGVYDGTEIHEASAILVHLSRGGAEVQIFAPDVPQMHVIDHTKGQPSEGESRNVLTESARIARGKITDLANLSAANHDAAIFPGGFGAAKNLSTFAVDGKDCKVNKEVERVLKEFHQAGKPIGLCCIAPVLAAKVLRGVEVTVGHEQEEGGKWPYAGTAEAIKALGAKHCVKEVVEAHVDQKNKVVTTPAFMCETALHYIHDGIGAMVRKVLELTGK
Atome Classification :
(20 SA)
.........10........20........30........40........50...---------..---------...60........70........80........90.-....-.-.-.100-........110.--.-.....120.------.-----.....130.......140...-....150.......160.....-..170.......180.---.------..--.------.-.---190.......200---------.---------.......210.......-220-.......230.......240.......250.......260......
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
M
A
A
V
R
A
L
V
A
S
R
L
A
A
A
S
A
FTSLSPGGRTPSQ
R
A
A
L
H
LSVPRPA
A
R
V
A
L
V
L
SGCGV---------YD---------GTEIHEA
S
A
I
L
V
H
LSRGG
A
E
V
Q
I
FAPDVP
Q
M
H
V
I
DH-TKGQ-P-S-EGE--SRNV
L
T
E
SARIA--R-GKITDLANL------S-----AANHD
A
A
IFPGGFGAAKN
L
S
T
-
F
A
VDGKDCKV
N
K
E
V
E
R
V
L
K
E
F
H
-QAGK
P
I
G
L
C
C
I
A
P
V
L
A
---
A
------
K
V
--L------R-G---
V
E
V
T
VGHEQEEG----------G---------KWPYA
G
T
A
E
A
I
K
A
L
G
A
K
-
H
C
V
-
K
E
V
V
E
A
H
VDQKN
K
V
VT
T
P
A
F
M
C
E
T
A
L
H
Y
I
H
D
G
I
G
A
M
V
R
K
V
L
E
LTGK
3
PsiBlast_PDB
92.17
44%
-84
- C4 -
-
1VHQ
-
ELBB_ECOLI
A:
[8-220]
-------------------------------------------
K
I
G
V
I
L
S
G
C
G
V
---------
Y
D
---------
G
S
E
I
H
E
A
V
L
T
L
L
A
I
S
R
S
G
A
Q
A
V
C
F
A
P
D
K
Q
Q
V
D
V
I
N
H
-
L
T
G
E
---
A
-
M
T
E
--
T
R
N
V
L
I
E
A
A
R
I
T
--
R
-
G
E
I
R
P
L
A
Q
A
------
D
-----
A
A
E
L
D
A
L
I
V
P
G
G
F
G
A
A
K
N
L
S
N
-
F
A
S
L
G
S
E
C
T
V
D
R
E
L
K
A
L
A
Q
A
M
H
-
Q
A
G
K
P
L
G
F
M
C
I
A
P
A
M
L
---
P
------
K
I
--
F
------
D
F
P
---
L
R
L
T
I
G
T
D
I
D
----------------------------
T
A
E
V
L
E
E
M
G
A
E
-
H
V
P
-
C
P
V
D
D
I
V
V
D
E
D
N
K
I
V
T
T
P
A
Y
M
L
A
Q
N
I
A
E
A
A
S
G
I
D
K
L
V
S
R
V
L
V
L
---
1
PsiBlast_PDB
91.00
44%
-84
- C4 -
-
5LIR
2
?
A:
[26-238]
-------------------------------------------
K
I
G
V
V
L
S
G
C
G
V
---------
Y
D
---------
G
T
E
I
H
E
A
V
L
T
L
L
A
I
A
R
S
G
A
Q
A
V
C
F
A
P
D
K
P
Q
A
D
V
I
N
H
-
L
T
G
E
---
A
-
M
A
E
--
T
R
N
V
L
I
E
A
A
R
I
T
--
R
-
G
D
I
R
P
L
S
Q
A
------
Q
-----
P
E
E
L
D
A
L
I
V
P
G
G
F
G
A
A
K
N
L
S
N
-
F
A
S
Q
G
S
E
C
R
V
D
S
D
V
V
A
L
A
K
A
M
H
-
Q
S
G
K
P
L
G
F
I
C
I
A
P
A
M
L
---
P
------
K
I
--
F
------
D
F
P
---
L
R
L
T
I
G
T
D
I
D
----------------------------
T
A
E
V
L
E
E
M
G
A
E
-
H
V
P
-
C
P
V
D
D
I
V
V
D
E
D
N
K
V
V
T
T
P
A
Y
M
L
A
Q
D
I
A
Q
A
A
S
G
I
D
K
L
V
S
R
V
L
V
L
---
2
PsiBlast_PDB
90.06
44%
-81
- C4 -
-
1OY1
-
ELBB_ECOLI
A:
[6-218]
-------------------------------------------
K
I
G
V
I
L
S
G
C
G
V
---------
Y
D
---------
G
S
E
I
H
E
A
V
L
T
L
L
A
I
S
R
S
G
A
Q
A
V
C
F
A
P
D
K
Q
Q
V
D
V
I
N
H
-
L
T
G
E
---
A
-
M
T
E
--
T
R
N
V
L
I
E
A
A
R
I
T
--
R
-
G
E
I
R
P
L
A
Q
A
------
D
-----
A
A
E
L
D
A
L
I
V
P
G
G
F
G
A
A
K
N
L
S
N
-
F
A
S
L
G
S
E
C
T
V
D
R
E
L
K
A
L
A
Q
A
M
H
-
Q
A
G
K
P
L
G
F
M
C
I
A
P
A
M
L
---
P
------
K
I
--
F
------
D
F
P
---
L
R
L
T
I
G
T
D
I
D
----------------------------
T
A
E
V
L
E
E
M
G
A
E
-
H
V
P
-
C
P
V
D
D
I
V
V
D
E
D
N
K
I
V
T
T
P
A
Y
M
L
A
Q
N
I
A
E
A
A
S
G
I
D
K
L
V
S
R
V
L
V
L
---
32
HHSearch
88.96
46%
-64
- C4 -
-
1VHQ
-
ELBB_ECOLI
B:
[6-221]
-----------------------------------------
M
K
K
I
G
V
I
L
S
G
C
G
V
---------
Y
D
---------
G
S
E
I
H
E
A
V
L
T
L
L
A
I
S
R
S
G
A
Q
A
V
C
F
A
P
D
K
Q
Q
V
D
V
I
N
H
-
L
T
G
E
-
A
-
M
-
T
-
E
--
T
R
N
V
L
I
E
A
A
R
I
T
--
R
-
G
E
I
R
P
L
A
Q
A
------
D
-----
A
A
E
L
D
A
L
I
V
P
G
G
F
G
A
A
K
N
L
S
N
-
F
A
S
L
G
S
E
C
T
V
D
R
E
L
K
A
L
A
Q
A
M
H
-
Q
A
G
K
P
L
G
F
M
C
I
A
P
A
M
L
PK-
I
------
F
---
D
------
F
-
P
---
L
R
L
T
I
G
T
D
I
D
-------------------------
T
---
A
E
V
L
E
E
M
G
A
E
-
H
V
P
-
C
P
V
D
D
I
V
V
D
E
D
N
K
I
V
T
T
P
A
Y
M
L
A
Q
N
I
A
E
A
A
S
G
I
D
K
L
V
S
R
V
L
V
L
A
--
4
PsiBlast_PDB
77.90
34%
-70
- C4 -
-
3L3B
-
?
A:
[3-211]
------------------------------------------
L
N
S
A
V
I
L
A
G
C
G
H
---------
M
D
---------
G
S
E
I
R
E
A
V
L
V
M
L
E
L
D
R
H
N
V
N
F
K
C
F
A
P
N
K
N
Q
K
Q
V
V
D
H
-
K
K
-
K
-
E
-
S
-
V
G
E
--
V
R
N
I
L
V
E
S
A
R
I
A
--
R
-
G
S
V
Y
D
I
E
Q
I
------
R
-----
V
E
E
F
D
M
L
V
I
P
G
G
Y
G
V
A
K
N
F
S
N
L
F
D
E
D
--
N
D
Y
I
L
P
E
F
K
N
A
V
R
E
F
Y
-
N
A
K
K
P
I
G
A
V
C
I
S
P
A
V
V
---
V
------
A
L
--
L
------
K
-
D
IAK
V
K
V
T
I
G
-
E
---------------------------------
L
I
D
K
M
G
G
V
-
H
V
D
-
C
P
T
I
K
S
V
K
D
D
V
N
R
I
F
S
C
S
A
Y
M
R
N
D
S
L
Y
N
V
Y
L
G
I
Q
D
M
I
---------
14
HHSearch
77.61
33%
-68
- C4 -
-
3L3B
-
?
B:
[2-219]
-----------------------------------------
A
L
N
S
A
V
I
L
A
G
C
G
H
---------
M
D
---------
G
S
E
I
R
E
A
V
L
V
M
L
E
L
D
R
H
N
V
N
F
K
C
F
A
P
N
K
N
Q
K
Q
V
V
D
H
-
K
K
K
E
-
S
-
V
--
G
E
--
V
R
N
I
L
V
E
S
A
R
I
A
--
R
-
G
S
V
Y
D
I
E
Q
I
------
R
-----
V
E
E
F
D
M
L
V
I
P
G
G
Y
G
V
A
K
N
F
S
N
-
L
F
D
----
D
Y
I
L
P
E
F
K
N
A
V
R
E
F
Y
-
N
A
K
K
P
I
G
A
V
C
I
S
P
A
V
V
VAL
L
------
K
D
--
I
------
A
-
K
---
V
K
V
T
I
G
E
D
S
------------------------------
N
G
L
I
D
K
M
G
G
V
-
H
V
D
-
C
P
T
I
K
S
V
K
D
D
V
N
R
I
F
S
C
S
A
Y
M
R
N
D
S
L
Y
N
V
Y
L
G
I
Q
D
M
I
S
S
M
V
N
Y
L
K
-
34
Fugue
71.75
45%
-34
- C4 -
-
1OY1
-
ELBB_ECOLI
A:
[5-224]
------------------------------------------
K
K
I
G
V
I
L
S
G
C
G
V
---------
Y
D
---------
G
S
E
I
H
E
A
V
L
T
L
L
A
I
S
R
S
G
A
Q
A
V
C
F
A
P
D
K
Q
Q
V
D
V
I
N
H
-
L
T
G
E
-
A
-
T
-
E
----
T
R
N
V
L
I
E
A
A
R
I
T
--
R
-
G
E
I
R
P
L
A
Q
A
------
D
-----
A
A
E
L
D
A
L
I
V
P
G
G
F
G
A
A
K
N
L
S
N
-
F
A
S
L
G
S
E
C
T
V
D
R
E
L
K
A
L
A
Q
-
A
H
-
Q
A
G
K
P
L
G
F
C
-
I
A
P
A
L
P
---
K
------
I
F
--
D
------
F
-
P
---
L
R
L
T
I
G
T
D
-----------------------------
I
D
T
A
E
V
L
E
E
G
A
E
-
H
V
P
-
C
P
V
D
D
I
V
V
D
E
D
N
K
I
V
T
T
P
A
Y
L
A
Q
N
-
I
A
E
A
A
S
G
I
D
K
L
V
S
R
V
L
V
L
A
E
L
29
HHSearch
62.38
21%
-64
- C4 -
-
4OFW
-
DJ1D_ARATH
A:
[190-383]
----------------------------------
G
G
K
I
T
G
A
N
K
R
I
L
F
L
C
G
--------------
D
---------
Y
M
E
D
Y
E
V
K
V
P
F
Q
S
L
Q
A
L
G
C
Q
V
D
A
V
C
P
E
K
K
A
G
E
-
R
C
P
-
T
A
I
H
-
D
-
F
-
E
G
---
D
Q
T
Y
S
E
-
K
P
G
H
T
--
F
-
A
L
T
T
N
F
D
D
L
------
V
-----
S
S
S
Y
D
A
L
V
I
P
G
G
R
A
P
E
Y
-
L
-----------
A
L
N
E
H
V
L
N
I
V
K
E
F
M
-
N
S
E
K
P
V
A
S
I
C
H
G
Q
Q
I
L
AA-
A
------
G
V
--
L
------
K
-
G
---
R
K
C
T
A
Y
P
A
V
K
------------------------------
L
N
V
V
L
G
G
G
T
-
W
L
E
-
P
D
P
I
D
R
C
F
-
T
D
G
N
L
V
T
G
A
A
W
P
----------
G
H
P
E
F
V
S
Q
L
M
A
L
L
G
-
21
HHSearch
61.46
20%
-57
- C4 -
-
4OGG
-
DJ1D_ARATH
A:
[191-383]
-----------------------------------
G
K
I
T
G
A
N
K
R
I
L
F
L
C
G
--------------
D
---------
Y
M
E
D
Y
E
V
K
V
P
F
Q
S
L
Q
A
L
G
C
Q
V
D
A
V
C
P
E
K
K
A
G
D
-
R
C
P
-
T
A
I
H
-
D
-
F
---
E
--
G
D
Q
T
Y
S
E
K
P
G
H
T
--
F
-
A
L
T
T
N
F
D
D
L
------
V
-----
S
S
S
Y
D
A
L
V
I
P
G
G
R
A
P
E
Y
-
L
-----------
A
L
N
E
H
V
L
N
I
V
K
E
F
M
-
N
S
E
K
P
V
A
S
I
-
H
G
Q
Q
I
L
AA-
A
------
G
V
--
L
------
K
-
G
---
R
K
C
T
A
Y
P
A
V
K
------------------------------
L
N
V
V
L
G
G
G
T
-
W
L
E
-
P
D
P
I
D
R
C
F
T
-
D
G
N
L
V
T
G
A
A
W
P
----------
G
H
P
E
F
V
S
Q
L
M
A
L
L
G
-
25
HHSearch
55.59
23%
-14
- C4 -
-
1OI4
-
YHBO_ECOLI
A:
[18-192]
------------------------------------
K
K
A
G
L
S
K
K
I
A
V
L
I
T
--------------
D
---------
E
F
E
D
S
E
F
T
S
P
A
D
E
F
R
K
A
G
H
E
V
I
T
I
E
K
Q
A
G
K
T
--
V
K
G
K
K
G
E
A
-
S
-
V
-
T
---------------------
I
D
K
S
I
D
E
V
------
T
-----
P
A
E
F
D
A
L
L
L
P
G
G
H
S
P
D
Y
-
L
-----------
R
G
D
N
R
F
V
T
F
T
R
D
F
V
-
N
S
G
K
P
V
F
A
I
C
H
G
P
Q
L
L
IS-
A
------
D
V
--
I
------
R
-
G
---
R
K
L
T
A
V
K
P
I
------------------------------
I
I
D
V
K
N
A
G
A
E
-
F
Y
D
-
Q
---
E
V
V
V
D
-
K
D
Q
L
V
T
S
R
T
P
D
----------
D
L
P
A
F
N
R
E
A
L
R
L
L
G
-
20
HHSearch
54.74
16%
-9
- C4 -
-
1N57
-
HCHA_ECOLI
A:
[45-277]
--------------------------------------
Y
R
G
K
H
K
I
L
V
I
A
A
D
E
R
Y
---------
L
P
TDNGKLFST
G
N
H
P
I
E
T
L
L
P
L
Y
H
L
H
A
A
G
F
E
F
E
V
A
T
I
S
G
L
M
T
K
--
F
E
-
Y
W
A
M
-
P
-
H
K
D
E
K
--
V
M
P
F
F
E
Q
H
-
K
S
L
--
F
-
R
N
P
K
K
L
A
D
V
------
V
ASLNA
D
S
E
Y
A
A
I
F
V
P
G
G
H
G
A
L
I
G
L
-----------
P
E
S
Q
D
V
A
A
A
L
Q
W
A
I
-
K
N
D
R
F
V
I
S
L
C
H
G
P
A
A
F
LA-
L
RHGD--
N
P
--
L
------
N
-
G
---
Y
S
I
C
A
F
P
D
A
A
D
K
QTPEIGYMP-
G
---------
H
L
T
W
Y
F
-
G
E
E
L
K
K
M
G
M
N
-
I
I
N
-
D
-
D
I
T
G
R
V
H
K
D
R
K
L
L
T
G
D
S
P
F
----------
A
A
N
A
L
G
K
L
A
A
Q
E
M
--
24
HHSearch
54.37
15%
-10
- C4 -
-
1ONS
-
HCHA_ECOLI
A:
[44-277]
--------------------------------------
Y
R
G
K
H
K
I
L
V
I
A
A
D
E
R
Y
---------
L
P
TDNGKLFST
G
N
H
P
I
E
T
L
L
P
L
Y
H
L
H
A
A
G
F
E
F
E
V
A
T
I
S
G
L
M
T
K
-
F
E
Y
--
W
A
M
-
P
H
K
-
D
E
K
--
V
M
P
F
F
E
Q
H
-
K
S
L
--
F
-
R
N
P
K
K
L
A
D
V
------
V
ASLNA
D
S
E
Y
A
A
I
F
V
P
G
G
H
G
A
L
I
G
L
-----------
P
E
S
Q
D
V
A
A
A
L
Q
W
A
I
-
K
N
D
R
F
V
I
S
L
C
H
G
P
A
A
F
LA-
L
RHGD--
N
P
--
L
------
N
-
G
---
Y
S
I
C
A
F
P
D
A
A
D
K
----------
Q
TPEIGYMPG
H
L
T
W
Y
F
-
G
E
E
L
K
K
M
G
M
N
-
I
I
N
-
D
-
D
I
T
G
R
V
H
K
D
R
K
L
L
T
G
D
S
P
F
----------
A
A
N
A
L
G
K
L
A
A
Q
E
M
L
-
33
HHSearch
54.33
17%
-58
* C4 *
-
4HCJ
1
?
A:
[5-174]
---------------------------------------
G
K
T
N
N
I
L
Y
V
M
S
G
-------------
Q
---------
N
F
Q
D
E
E
Y
F
E
S
K
K
I
F
E
S
A
G
Y
K
T
K
V
S
S
T
F
I
G
T
A
---
Q
G
-
K
L
G
G
-
M
-
T
-
N
---------------------
I
D
L
L
F
S
E
V
------
D
-----
A
V
E
F
D
A
V
V
F
V
G
G
I
G
C
I
T
-
L
-----------
W
D
D
W
R
T
Q
G
L
A
K
L
F
L
-
D
N
Q
K
I
V
A
G
I
G
S
G
V
V
I
M
AN-
A
------
K
I
--
L
------
E
-
E
---
I
N
V
T
C
L
S
A
D
------------------------------
E
S
H
V
R
H
G
N
A
N
-
I
M
S
-
E
---
N
V
V
V
--
S
G
N
I
V
T
A
N
G
P
T
----------
S
S
K
D
F
A
N
A
V
V
G
V
L
N
-
39
Fugue
54.06
27%
-58
- C4 -
-
4QYT
3
DJ1_SCHPO
A:
[5-194]
------------------------------------------
V
K
V
C
L
F
V
A
--------------
D
---------
G
T
D
E
I
E
F
S
A
P
W
G
I
F
K
R
A
E
I
P
I
D
S
V
Y
V
G
E
N
K
D
R
L
V
K
-------------
M
--
S
R
D
V
-
E
M
Y
A
N
R
S
--
Y
-
K
E
I
P
S
A
D
D
F
------
A
-----
K
Q
-
Y
D
I
A
I
I
P
G
G
G
L
G
A
K
T
L
S
T
-----------
T
P
F
V
Q
Q
V
V
K
E
F
Y
K
K
P
N
K
W
I
G
M
--
I
A
G
T
L
T
---
A
------
K
T
SG
L
------
P
-
N
---
K
Q
I
T
-
G
H
-----------------------------
P
S
V
R
G
Q
L
E
E
G
G
Y
K
Y
L
D
Q
-
P
V
V
L
E
E
N
L
I
T
S
Q
G
P
G
T
A
M
L
F
G
L
K
L
L
E
Q
V
A
S
K
D
K
Y
N
A
V
Y
K
S
L
S
M
P
--
31
HHSearch
53.69
20%
-61
- C4 -
-
1G2I
-
DEGLY_PYRHO
B:
[1-166]
------------------------------------------
M
K
V
L
F
L
T
A
--------------
N
---------
E
F
E
D
V
E
L
I
Y
P
Y
H
R
L
K
E
E
G
H
E
V
Y
I
A
S
F
E
R
G
T
I
---
T
G
-
K
H
G
Y
-
S
-
V
-
K
---------------------
V
D
L
T
F
D
K
V
------
N
-----
P
E
E
F
D
A
L
V
L
P
G
G
R
A
P
E
R
-
V
-----------
R
L
N
E
K
A
V
S
I
A
R
K
M
F
-
S
E
G
K
P
V
A
S
I
C
H
G
P
Q
I
L
IS-
A
------
G
V
--
L
------
R
-
G
---
R
K
G
T
S
Y
P
G
I
K
------------------------------
D
D
M
I
N
A
G
V
E
-
W
V
D
----
A
E
V
V
V
--
D
G
N
W
V
S
S
R
V
P
A
----------
D
L
Y
A
W
M
R
E
F
V
K
L
L
K
-
30
HHSearch
53.26
20%
-63
- C4 -
-
6F2F
2
DEGLY_PYRHO
C:
[1-166]
------------------------------------------
M
K
V
L
F
L
T
A
--------------
N
---------
E
F
E
D
V
E
L
I
Y
P
Y
H
R
L
K
E
E
G
H
E
V
Y
I
A
S
F
E
R
G
T
I
---
T
G
-
K
H
G
Y
-
S
-
V
-
K
---------------------
V
D
L
T
F
D
K
V
------
N
-----
P
E
E
F
D
A
L
V
L
P
G
G
R
A
P
E
R
-
V
-----------
R
L
N
E
K
A
V
S
I
A
R
K
M
F
-
S
E
G
K
P
V
A
S
I
C
H
G
P
Q
I
L
IS-
A
------
G
V
--
L
------
R
-
G
---
R
K
G
T
S
Y
P
G
I
K
------------------------------
D
D
M
I
N
A
G
V
E
-
W
V
D
----
A
E
V
V
V
--
D
G
N
W
V
S
S
R
V
P
A
----------
D
L
Y
A
W
M
R
E
F
V
K
L
L
K
-
18
HHSearch
52.42
15%
0
- C4 -
-
4I4N
-
?
F:
[47-280]
--------------------------------------
Q
G
G
R
W
K
I
L
V
V
G
A
D
E
R
Y
LMMDNGTFF
S
T
---------
G
N
H
P
V
E
T
L
L
P
M
Y
H
L
D
K
A
G
F
S
F
D
I
A
T
L
S
G
N
P
V
K
-
F
E
W
-
W
A
M
P
-
R
-
E
-
D
Q
E
--
V
N
G
L
Y
S
K
-
Y
Q
S
S
--
F
-
R
Q
P
L
K
L
S
D
V
IETALG
E
-----
D
S
D
Y
I
G
V
F
I
P
G
G
H
G
A
L
M
G
L
-----------
P
D
S
Q
E
V
K
A
V
L
Q
W
A
M
-
K
Q
N
K
F
I
I
S
L
A
H
G
P
A
A
F
LA-
V
GDD---
P
L
--
F
------
A
-
G
---
Y
K
I
V
A
F
P
D
E
M
D
A
QT--------
P
SIGYMPG--
H
L
T
W
K
F
-
G
E
Q
L
Q
A
I
G
F
E
-
L
L
N
-
T
G
I
S
G
Q
V
F
-
Q
D
R
K
M
L
T
G
D
S
P
L
----------
A
G
N
A
L
G
Q
L
A
A
K
A
L
L
-
23
HHSearch
48.41
15%
5
- C4 -
-
3N7T
1
?
A:
[7-242]
--------------------------------------
P
L
P
R
K
A
L
L
A
I
T
S
A
H
P
P
---------
F
W
PDGKRT---
G
L
F
F
S
E
A
L
H
P
F
N
E
L
T
A
A
G
F
E
V
D
V
A
S
E
T
G
T
F
G
--
W
D
E
-
H
S
L
T
Q
E
-
Y
-
L
S
K
ED
E
K
V
L
H
S
E
H
N
H
F
M
EK
M
N
K
Q
V
F
K
A
G
D
L
------
A
-----
P
H
D
Y
G
L
M
F
V
C
G
G
H
G
A
L
Y
D
F
-----------
P
H
A
K
H
L
Q
N
I
A
Q
D
I
Y
-
K
R
G
G
V
I
G
A
V
C
H
G
P
A
M
L
PG-
I
HDENGD
S
V
--
I
------
K
-
D
---
K
T
V
T
G
F
T
T
K
G
E
I
----------
M
IKVIDKMRE
D
H
L
H
T
I
-
A
D
M
A
Q
T
A
N
A
E
-
Y
V
P
P
E
D
P
W
D
D
F
C
K
V
D
G
R
I
V
T
G
A
N
P
Q
----------
S
A
T
N
T
A
R
D
T
I
K
V
Y
E
-
16
HHSearch
47.28
14%
14
- C4 -
-
5XR2
-
HCHA_STAA8
G:
[50-285]
---------------------------------------
D
G
K
W
K
V
L
M
I
A
A
E
E
R
Y
VLLENGKMF
S
T
---------
G
N
H
P
V
E
M
L
L
P
L
H
H
L
M
E
A
G
F
D
V
D
V
A
T
L
S
G
Y
P
V
K
-
L
E
L
-
W
A
M
P
-
T
-
E
-
D
E
A
--
V
I
S
T
Y
N
K
L
-
K
E
K
--
L
-
K
Q
P
K
K
L
A
D
V
IKNELG
P
-----
D
S
D
Y
L
S
V
F
I
P
G
G
H
A
A
V
V
G
I
-----------
S
E
S
E
D
V
Q
Q
T
L
D
W
A
L
-
D
N
D
R
F
I
V
T
L
C
H
G
P
A
A
L
LS-
A
------
G
L
--
N
REKSPL
E
-
G
---
Y
S
V
C
V
F
P
D
S
L
D
E
GANIEIGYLP
G
---------
R
L
K
W
L
V
-
A
D
L
L
T
K
Q
G
L
K
-
V
V
N
-
D
-
D
M
T
G
R
T
L
K
D
R
K
L
L
T
G
D
S
P
L
----------
A
S
N
E
L
G
K
L
A
V
N
E
M
--
15
HHSearch
46.76
14%
13
- C4 -
-
5XR2
-
HCHA_STAA8
F:
[50-285]
---------------------------------------
D
G
K
W
K
V
L
M
I
A
A
E
E
R
Y
VLLENGKMF
S
T
---------
G
N
H
P
V
E
M
L
L
P
L
H
H
L
M
E
A
G
F
D
V
D
V
A
T
L
S
G
Y
P
V
K
-
L
E
L
-
W
A
M
P
-
T
-
E
-
D
E
A
--
V
I
S
T
Y
N
K
L
-
K
E
K
--
L
-
K
Q
P
K
K
L
A
D
V
IKNELG
P
-----
D
S
D
Y
L
S
V
F
I
P
G
G
H
A
A
V
V
G
I
-----------
S
E
S
E
D
V
Q
Q
T
L
D
W
A
L
-
D
N
D
R
F
I
V
T
L
C
H
G
P
A
A
L
LS-
A
------
G
L
--
N
REKSPL
E
-
G
---
Y
S
V
C
V
F
P
D
S
L
D
E
GANIEIGYLP
G
---------
R
L
K
W
L
V
-
A
D
L
L
T
K
Q
G
L
K
-
V
V
N
-
D
-
D
M
T
G
R
T
L
K
D
R
K
L
L
T
G
D
S
P
L
----------
A
S
N
E
L
G
K
L
A
V
N
E
M
--