Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence EQARYHGQCVVEIYNSQNQRADILHSQIWMR--------ETLP-DYTLHPLSRYAVLVDGDCNARAEYGIAPPGNTFRGCTAYE 6GHD Chain:B ((23-74)) --------KFVRLRNKSNEDQSMGNWQIKRQNGDDPLLTYRFPPKFTLKAGQVVTIWAAG------------------------

General information: TITO was launched using: RESULT: Template: 6GHD.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 92 -6008 -65.30 -139.71 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain B : 0.67 3D Compatibility (PKB) : -65.30 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.230

(partial model without unconserved sides chains): PDB file : Tito_6GHD.pdb: (Unconserved sides chains are recalculated) : Sequence: align-6ghd-query.scw PDB file : Tito_Scwrl_6GHD.pdb: