Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSAAEMGMAETADLRTRLAPLFPGREISLRSAAAPVASPLHRAVASACVLAQPDGADPLFLKLAHPDMQDDLLDTDGAAARLAARAGVAPALVLARPGLLGFAYLALPWRYARTGDLQPPATLAAVLAAKKRLH-EGDNLGRRFCPFTRIAQLQAQAEAAQVPLPAETAPLLRQAALIQQALIASGMDLRFCHNHAAASNIMLNGSQMMLVDFDIGGDNDPWYDVGALLNEVCDFDAPRRAAIE--AYAGRCDEALFARCRLYGAVDDLMWGLWGFTR-AVTAPRDGIEFWKYGTWRLFQARTTMTMRDFELWLRTV 3DXQ Chain:A ((103-297)) -----------------------------------------------------------------------------------------------------------------------PGSPARAGEAFRKLHGSGAVFPFRFELFAMIDDYLKVLS--NVTLPAGYHDVVREAGGVRSALAAHPLPLAACHCDPLCENFLDTGERMWIVDWEYSGMNDPLWDLGDLSVE-GKFNANQDEELMRAYFGGEARPAERGRVVIYKAMCDLLWTLWGLIQLANDNPVD--DFRAYADGRFARCKALMETPEFSRHLAAV

General information: TITO was launched using: RESULT: Template: 3DXQ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 798 -43271 -54.22 -228.95 target 2D structure prediction score : 0.72 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : -54.22 2D Compatibility (Sec. Struct. Predict.) : 0.72 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.268

(partial model without unconserved sides chains): PDB file : Tito_3DXQ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3dxq-query.scw PDB file : Tito_Scwrl_3DXQ.pdb: