Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAAPAQSEQMRRLAGLLGVKLDPFSTGGESLTFGITGTELLVTIPTEP-GEQDVQRQAELTRRVADRISIPVPEIVRVVAEAEAVVVR-----RLPGVPLIAVPTPQRAALTRSVALA-VGTVLAELHTWDRDGYADLAPVDEYSPEEWRAETAELVSDLTPLLTTDQR-------DDVRRFLGRPAPRPAGRHVLSHNDLGIEHILV--SPDAVTGVIDWNDAAITDPAYDFGLLLRD---LGPEALRTALARYAHQIGGDPELLERASYYAVCALLEDLAFGHETGRVEYVAKSLHGWRWTFQAAG 6CD7 Chain:A ((32-297)) --------------------------GNDCIAYEIN-RDFIFKFPKHSRGSTNLFNEVNILKRIHNKLPLPIPEVVFTGMPSETYQMSFAGFTKIKGVPLTPLLLNNLPKQSQNQAAKDLARFLSELHSINISGFKSNLVLD------FREKINEDNKKIKKLLSRELKGPQMKKVDDFYRDILENEIYFKYYPCLIHNDFSSDHILFDTEKNTICGIIDFGDAAISDPDNDFISLMEDDEEYGMEFVSKILNHYKHK--DIPTVLEKYRMKEKYWSFEKIIYGKEYGYMDWYEEGLNEIR-------

General information: TITO was launched using: RESULT: Template: 6CD7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1081 -5539 -5.12 -22.43 target 2D structure prediction score : 0.70 Monomeric hydrophicity matching model chain A : 0.72 3D Compatibility (PKB) : -5.12 2D Compatibility (Sec. Struct. Predict.) : 0.70 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.349

(partial model without unconserved sides chains): PDB file : Tito_6CD7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-6cd7-query.scw PDB file : Tito_Scwrl_6CD7.pdb: