Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MADRFIGSAVAVPASLDWLRATETGRIWLDKLPVLLETACEHFGLSE--IGSPFSGGNVSLVVPARHDGEDVVLKLQFPD----HECRHEAEALWRWNG-KG--AVRLLKHA------------PELGALLLERCRPGQFLADDT-ETDRIGVVAGLLRLLTIPAGD-PFTR-LNDEAARWRDSLD---H---NWMAA-GKPCEQYLVDAA----RKALQDLCLEKEAEEVLLHQDLHGHNILSSER---DTWLAIDPK-PLAGDPAFALSPIVRSFEFGH-SKAEARYRLDRLSEELEL---DRERARYWTIGQTMAWAFSSSYAERHFETVRWLLAEN 6EF6 Chain:A ((31-320)) -----------------------------------AQQALTHYDVSDNASLRLL-NLSENATYLVEDGEHQSILRVHRQDYHQPHEIESELDWLAALRTDSDVTVPTVVPARDGRRVVTVDPADVPRHVVHFEMV-GGAEPDEESLTLDDFQTLGRITASLHEHSQRWTRPAGFGRFSWDWEHCLGDTPRWGRWQDAEGVGASETALLTRAQDLLHRKLEEYGS-GPDRYGLIHADLRLANLLVDSSTPQRTITVIDFDDCGFGWYFYDFGTAVSFIEHDPRLGEWQESWVAGYRSRRELPAADEAMLPSFVFLRRLLLLAWMGS---------------

General information: TITO was launched using: RESULT: Template: 6EF6.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1058 5002 4.73 20.50 target 2D structure prediction score : 0.62 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : 4.73 2D Compatibility (Sec. Struct. Predict.) : 0.62 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.338

(partial model without unconserved sides chains): PDB file : Tito_6EF6.pdb: (Unconserved sides chains are recalculated) : Sequence: align-6ef6-query.scw PDB file : Tito_Scwrl_6EF6.pdb: