Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEVEDVRLGAELERLTEGATWCPVWHLQRPLSPTTATAAPPLPSSTYLKMAPAGTLAADVAVMQLLKSCDVPAPHVLHYAQGGEGQADFLLISALAGV-HGATAEALSRPEALVRSFAGGLQSLHGQHSTALLRSAEDLGAKFDRRVAVRVARVERRLRVG--EVPGHAERLEAILAHVAKPPPNVESDLVFTHGDYCLPNVIFQILNNQAGETEAELRVVGFVDLGSAGVADRYVDLASAVWSLRFNGLEKHVPAFLQCYTARSELSGHKITINQDKLDWYINMFTLT 3DXQ Chain:B ((25-250)) -----------------------RLGGL-TNLVFRA-G------DLCLRIP---NRANEAVAAREAAKAGVS-PEVLHVDP----ATGVMVTRYIAGAQTMSPEKFK-TRPGSPARAGEAFRKLHG-SGAVFPF-----RFE----LFAMIDDYLKVLSTKNVTLPAGYHDVVREAGGVRSALAAHPLPLAACHCDPLCENFLDT--G----------ERMWIVDWEYSGMNDPLWDLGDLSVEGK--FNANQDEELMRAYFG---GEAR--PAERGRVVIYKAMCD--

General information: TITO was launched using: RESULT: Template: 3DXQ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 972 -49708 -51.14 -231.20 target 2D structure prediction score : 0.62 Monomeric hydrophicity matching model chain B : 0.66 3D Compatibility (PKB) : -51.14 2D Compatibility (Sec. Struct. Predict.) : 0.62 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.285

(partial model without unconserved sides chains): PDB file : Tito_3DXQ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3dxq-query.scw PDB file : Tito_Scwrl_3DXQ.pdb: