Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSEEVEKINLDDY---AATGEGATAISYTHKTRDTIAKLYHPGFEADCAKKDFLTSCTAFALGVPTPKPIRLVTDGERFGAEYELIRN-KRSFSRIIS-----EEPGRLQELSLIFAEMAKKLHSTKADTSKLVSTKEKFRRFYLEKAVVPDFYKQKALAFINTVPNTPTCLHGDLQISNVITDGKRTLWIDMGDFGY-------------GDPGWDLGMLWSMTNRMDEQKAD------LVFHM--------NKEKLLAHWNIFFPAYLGTTDPQKIAEATKRILPFAAVKIPYMFYIAKHFTLPDEAYPYIAKLFG----- 1XQZ Chain:A ((32-308)) --EPLE----SQYQVGPLLGSGGFGSVYSGIRVSD-------NLP--VAIK---------HVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDS---FVLIL-ERP----EPVQDLFDFITERGALQ----EEL--ARSFFWQVLEAVRHCHNCGVL-HRDIKDENILIDLNRGE-LKLIDFGSGALLKDTVYTDFDGTRVY-SPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEEIIR-GQVFFRQRV----SSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETAEIHLHSLS

General information: TITO was launched using: RESULT: Template: 1XQZ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1174 18425 15.69 78.07 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : 15.69 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.236

(partial model without unconserved sides chains): PDB file : Tito_1XQZ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1xqz-query.scw PDB file : Tito_Scwrl_1XQZ.pdb: