Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKNIPNFNSFVKVEPIHKGWSGDKKYYVEAENGERFLLRVSDISK--YKEKESEFEIMKKMSATGMKMSLPISFGVCENEKSVYQLLTWCDGV-EAKEALYNLSDEEQYIFGQKAAKILRQIETIDYKPASEE-WVISYQERVKYYIELYRKCGYTFDGDEMVISYLQTGLQHIGERPTALMHNDFQTDNMVISPDGELYIIDFQMCGIADPYHVLTGVGVSAMYSIPFAKGQIEEYFGRNVPEDFWEKYNHYMLAEMLYSFTVGVNMEEERENTLHMFDDEVERIKNNGSHIPKWYQKKI 4R78 Chain:A ((37-278)) -------EEVLSVEQL-GGMTNQ-NYLAKTT-NKQYIVKFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDI-----EAGIKVNEYIESAITLDSTS-------IKTKFDKIAPILQTIHTSAK-ELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAV-FSLEKRLA-DLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTSQEEETFLSHYESD-QTPVSHEKIAIYKILQDTIWSLWTVYK---------------------------------

General information: TITO was launched using: RESULT: Template: 4R78.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1067 14590 13.67 61.30 target 2D structure prediction score : 0.62 Monomeric hydrophicity matching model chain A : 0.67 3D Compatibility (PKB) : 13.67 2D Compatibility (Sec. Struct. Predict.) : 0.62 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.305

(partial model without unconserved sides chains): PDB file : Tito_4R78.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4r78-query.scw PDB file : Tito_Scwrl_4R78.pdb: